JP2015523072A5 - - Google Patents

Download PDF

Info

Publication number
JP2015523072A5
JP2015523072A5 JP2015520567A JP2015520567A JP2015523072A5 JP 2015523072 A5 JP2015523072 A5 JP 2015523072A5 JP 2015520567 A JP2015520567 A JP 2015520567A JP 2015520567 A JP2015520567 A JP 2015520567A JP 2015523072 A5 JP2015523072 A5 JP 2015523072A5
Authority
JP
Japan
Prior art keywords
composition
purified recombinant
seq
conversion
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2015520567A
Other languages
English (en)
Japanese (ja)
Other versions
JP6171007B2 (ja
JP2015523072A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2013/048561 external-priority patent/WO2014005014A2/en
Publication of JP2015523072A publication Critical patent/JP2015523072A/ja
Publication of JP2015523072A5 publication Critical patent/JP2015523072A5/ja
Application granted granted Critical
Publication of JP6171007B2 publication Critical patent/JP6171007B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2015520567A 2012-06-29 2013-06-28 組換えイズロン酸２スルファターゼの精製 Active JP6171007B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261666733P 2012-06-29 2012-06-29
US61/666,733 2012-06-29
PCT/US2013/048561 WO2014005014A2 (en) 2012-06-29 2013-06-28 Purification of iduronate-2-sulfatase

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016060910A Division JP6505629B2 (ja) 2012-06-29 2016-03-24 組換えイズロン酸２スルファターゼの精製

Publications (3)

Publication Number Publication Date
JP2015523072A JP2015523072A (ja) 2015-08-13
JP2015523072A5 true JP2015523072A5 (show.php) 2016-01-07
JP6171007B2 JP6171007B2 (ja) 2017-07-26

Family

ID=49778401

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2015520567A Active JP6171007B2 (ja) 2012-06-29 2013-06-28 組換えイズロン酸２スルファターゼの精製
JP2016060910A Active JP6505629B2 (ja) 2012-06-29 2016-03-24 組換えイズロン酸２スルファターゼの精製
JP2018067404A Withdrawn JP2018121645A (ja) 2012-06-29 2018-03-30 組換えイズロン酸２スルファターゼの精製
JP2020037811A Active JP7594365B2 (ja) 2012-06-29 2020-03-05 組換えイズロン酸２スルファターゼの精製

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2016060910A Active JP6505629B2 (ja) 2012-06-29 2016-03-24 組換えイズロン酸２スルファターゼの精製
JP2018067404A Withdrawn JP2018121645A (ja) 2012-06-29 2018-03-30 組換えイズロン酸２スルファターゼの精製
JP2020037811A Active JP7594365B2 (ja) 2012-06-29 2020-03-05 組換えイズロン酸２スルファターゼの精製

Country Status (39)

Country Link
US (7) US9051556B2 (show.php)
EP (2) EP2867245B1 (show.php)
JP (4) JP6171007B2 (show.php)
KR (5) KR101380740B1 (show.php)
CN (3) CN104583225A (show.php)
AR (1) AR091647A1 (show.php)
AU (3) AU2013282395C1 (show.php)
BR (1) BR112014032567B1 (show.php)
CA (2) CA2877517C (show.php)
CL (1) CL2014003567A1 (show.php)
CO (1) CO7240396A2 (show.php)
CR (1) CR20140588A (show.php)
CY (1) CY1121519T1 (show.php)
DK (1) DK2867245T3 (show.php)
DO (1) DOP2014000294A (show.php)
EA (2) EA202090044A1 (show.php)
ES (1) ES2689468T3 (show.php)
GT (1) GT201400303A (show.php)
HK (3) HK1209431A1 (show.php)
HR (1) HRP20181897T1 (show.php)
HU (1) HUE040769T2 (show.php)
IL (4) IL236315A (show.php)
LT (1) LT2867245T (show.php)
MX (3) MX336715B (show.php)
MY (3) MY192068A (show.php)
NZ (3) NZ733366A (show.php)
PE (1) PE20150720A1 (show.php)
PH (3) PH12014502871A1 (show.php)
PL (1) PL2867245T3 (show.php)
PT (1) PT2867245T (show.php)
RS (1) RS58005B1 (show.php)
SG (2) SG11201408761VA (show.php)
SI (1) SI2867245T1 (show.php)
SM (1) SMT201800612T1 (show.php)
TR (1) TR201815811T4 (show.php)
TW (2) TWI587869B (show.php)
UA (2) UA129561C2 (show.php)
WO (1) WO2014005014A2 (show.php)
ZA (2) ZA201409397B (show.php)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5901877B2 (ja) 2007-07-27 2016-04-13 アーメイゲン・テクノロジーズ・インコーポレイテッドＡｒｍａｇｅｎ Ｔｅｃｈｎｏｌｏｇｉｅｓ， Ｉｎｃ． 中枢神経系のα−Ｌ−イデュロニダーゼ活性を増加させるための方法および組成物
ES2725200T3 (es) 2009-10-09 2019-09-20 Armagen Inc Métodos y composiciones para aumentar la actividad de iduronato 2-sulfatasa en el SNC
US20160145589A1 (en) 2011-06-24 2016-05-26 Green Cross Corporation Composition and formulation comprising recombinant human iduronate-2-sulfatase and preparation method thereof
KR101158673B1 (ko) 2011-06-24 2012-07-03 주식회사 지씨바이오 재조합 인간 이듀로네이트-2-설파타아제를 포함하는 조성물, 제제 및 이의 제조방법
KR101380740B1 (ko) 2012-06-29 2014-04-11 쉐어 휴먼 제네텍 세러피스, 인코포레이티드 이듀로네이트-2-설파타제의 정제
US9150841B2 (en) 2012-06-29 2015-10-06 Shire Human Genetic Therapies, Inc. Cells for producing recombinant iduronate-2-sulfatase
CA3034589A1 (en) 2016-08-25 2018-03-01 Jcr Pharmaceuticals Co., Ltd. Method for producing antibody fusion protein
CN106282231B (zh) * 2016-09-06 2020-01-03 陕西慧康生物科技有限责任公司 粘多糖贮积症ii型动物模型的构建方法及应用
CN106428420B (zh) * 2016-10-17 2018-08-21 上海江南长兴造船有限责任公司 一种用于超大型集装箱船止裂钢舱口围的安装的方法
MA50746A (fr) 2017-10-02 2020-08-12 Denali Therapeutics Inc Protéines de fusion comprenant des enzymes d'enzymothérapie substitutive
WO2020033867A2 (en) 2018-08-10 2020-02-13 Alexion Pharmaceuticals, Inc. Methods of treating neurofibromatosis type 1 and related conditions with alkaline phosphatase
EP3898689A1 (en) * 2018-12-20 2021-10-27 Armagen, Inc. Purification of iduronate-2-sulfatase immunoglobulin fusion protein
CA3127228A1 (en) * 2019-01-30 2020-08-06 Amgen Inc. Aflibercept attributes and methods of characterizing and modifying thereof
JP7796645B2 (ja) 2019-12-09 2026-01-09 アレクシオン ファーマシューティカルズ， インコーポレイテッド アルカリホスファターゼポリペプチド及びその使用方法
KR20230088811A (ko) * 2020-10-23 2023-06-20 알렉시온 파마슈티칼스, 인코포레이티드 알칼리성 포스파타제의 제조 동안 총 시알산 함량(tsac)을 제어하는 방법
CA3173631A1 (en) 2021-02-12 2022-08-18 Walter C. Voegtli Alkaline phosphatase polypeptides and methods of use thereof

Family Cites Families (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK6488D0 (da) 1988-01-07 1988-01-07 Novo Industri As Enzymer
US5310646A (en) 1988-05-13 1994-05-10 Regents Of The University Of Minnesota Method for the detection of mucopolysaccharide storage diseases
US5932211A (en) * 1991-11-12 1999-08-03 Women's And Children's Hospital Glycosylation variants of iduronate 2-sulfatase
AU700369B2 (en) 1994-03-16 1999-01-07 Regents Of The University Of California, The Treating inflammation via the administration of specific sulfatase enzymes and/or sulfation inhibitor
US5863782A (en) 1995-04-19 1999-01-26 Women's And Children's Hospital Synthetic mammalian sulphamidase and genetic sequences encoding same
DE19527054A1 (de) 1995-07-26 1997-01-30 Behringwerke Ag Verfahren zur Charakterisierung der Glycosylierung von Glycoproteinen sowie zur in-vitro Bestimmung der Bioverfügbarkeit von Glycoproteinen
WO1998008934A1 (en) 1996-08-30 1998-03-05 Life Technologies, Inc. Serum-free mammalian cell culture medium, and uses thereof
US7368531B2 (en) 1997-03-07 2008-05-06 Human Genome Sciences, Inc. Human secreted proteins
US7083793B2 (en) 1999-02-26 2006-08-01 Millennium Pharmaceuticals, Inc. Tango 243 polypeptides and uses thereof
EP1179000A4 (en) 1999-02-26 2005-10-12 Millennium Pharm Inc DECISION PROTEINS AND THEIR USE
DE60032349T2 (de) 1999-04-26 2007-07-12 Genentech, Inc., South San Francisco Zellenzuchtverfahren für glycoproteine
JP2002017376A (ja) 1999-07-08 2002-01-22 Herikkusu Kenkyusho:Kk 分泌蛋白質、または膜蛋白質
AU7099200A (en) 1999-09-03 2001-04-10 Human Genome Sciences, Inc. 52 human secreted proteins
US6780627B1 (en) 2000-01-31 2004-08-24 Millennium Pharmaceuticals, Inc. 22438, 23553, 25278, and 26212 novel human sulfatases
AU2001238488A1 (en) 2000-02-17 2001-08-27 Incyte Genomics, Inc. Human kinases
EP1268541A1 (en) 2000-03-17 2003-01-02 Human Genome Sciences, Inc. 7 human ovarian and ovarian cancer associated proteins
JP2003530838A (ja) 2000-04-12 2003-10-21 ヒューマン ゲノム サイエンシズ インコーポレイテッド アルブミン融合タンパク質
US20030148920A1 (en) 2000-12-27 2003-08-07 Steven Rosen Sulfatases and methods of use thereof
WO2002098455A2 (en) 2001-06-07 2002-12-12 Hemebiotech A/S Production of recombinant human arylsulfatase a
AU2003265235A1 (en) 2002-04-26 2003-12-19 Genetech, Inc. Non-affinity purification of proteins
US6890736B1 (en) 2002-09-20 2005-05-10 Immunex Corporation Methods for producing proteins in cultured cells
JP4541157B2 (ja) 2002-12-23 2010-09-08 ブリストル−マイヤーズ スクイブ カンパニー タンパク質を製造するための哺乳類細胞培養法
JP4606712B2 (ja) * 2003-01-08 2011-01-05 マサチューセッツ インスティテュート オブ テクノロジー ２−ｏスルファターゼ組成物および関連の方法
SI2325302T1 (sl) 2003-02-11 2016-05-31 Shire Human Genetic Therapies, Inc. Celice, ki soizražajo sulfatazo in c-formilglicin generirajoči encim ter postopki in uporabe le-teh
US20050019914A1 (en) 2003-07-24 2005-01-27 Aventis Pharma Deutschland Gmbh Perfusion process for producing erythropoietin
JP4586027B2 (ja) 2004-01-30 2010-11-24 シャイア ファーマシューティカルズ アイルランド リミテッド 組換えアリールスルファターゼａの製造及び精製
WO2005113765A2 (en) 2004-05-06 2005-12-01 Biomarin Pharmaceutical Inc. Methods of activation of sulfatases and methods and compositions of using the same
EP2267024B1 (en) 2005-06-03 2012-05-09 Ares Trading S.A. Production of recombinant Il-18 binding protein
US20100190210A1 (en) 2006-03-20 2010-07-29 Medarex, Inc. Protein Purification
JP4458377B2 (ja) 2007-06-29 2010-04-28 キヤノン株式会社 プロセスカートリッジ及び電子写真画像形成装置
US20130195888A1 (en) 2007-11-30 2013-08-01 Abbvie Ultrafiltration and diafiltration formulation methods for protein processing
MX2010007846A (es) * 2008-01-18 2010-10-05 Biomarin Pharm Inc Fabricación de enzimas sulfatasa lisosomal humana altamente fosforilada, activa y usos de las mismas.
ES2725200T3 (es) 2009-10-09 2019-09-20 Armagen Inc Métodos y composiciones para aumentar la actividad de iduronato 2-sulfatasa en el SNC
JPWO2011108451A1 (ja) * 2010-03-01 2013-06-27 日本ケミカルリサーチ株式会社 遺伝子ノックアウト細胞を用いた組換え体リソソーム酵素の製造方法
NZ702801A (en) * 2010-06-25 2016-08-26 Shire Human Genetic Therapies Treatment of sanfilippo syndrome type b
PL2593131T3 (pl) 2010-06-25 2020-01-31 Shire Human Genetic Therapies, Inc. Sposoby i kompozycje do dostarczania sulfatazy-2-iduronianiu do oun
AR082319A1 (es) 2010-07-22 2012-11-28 Biomarin Pharm Inc Produccion de una n-acetilgalactosamina-6-sulfatasa humana activa altamente fosforilada y sus usos
WO2012042857A1 (ja) 2010-09-28 2012-04-05 共立製薬株式会社 粘膜アジュバント組成物
WO2012101671A1 (en) 2011-01-25 2012-08-02 Jcr Pharmaceuticals Co., Ltd. Method for production of human recombinant iduronate 2-sulfatase
KR20130114704A (ko) 2011-01-31 2013-10-17 휴렛-팩커드 디벨롭먼트 컴퍼니, 엘.피. 동적으로 튜닝 가능한 산란각을 갖는 산광기
KR101158673B1 (ko) 2011-06-24 2012-07-03 주식회사 지씨바이오 재조합 인간 이듀로네이트-2-설파타아제를 포함하는 조성물, 제제 및 이의 제조방법
US9150841B2 (en) 2012-06-29 2015-10-06 Shire Human Genetic Therapies, Inc. Cells for producing recombinant iduronate-2-sulfatase
KR101380740B1 (ko) * 2012-06-29 2014-04-11 쉐어 휴먼 제네텍 세러피스, 인코포레이티드 이듀로네이트-2-설파타제의 정제
US20140004097A1 (en) 2012-06-29 2014-01-02 Shire Human Genetic Therapies, Inc. Method of producing recombinant iduronate-2-sulfatase
KR20190062745A (ko) 2017-11-29 2019-06-07 주식회사 위니플 쇼핑몰 모바일앱 빌더

Similar Documents

Publication Publication Date Title
JP2015523072A5 (show.php)
AR091647A1 (es) Purificacion de iduronato-2-sulfatasa
TR201900128T4 (tr) Amino asit 1'de ve 3'te modifiye edilmiş siklosporin analoğu moleküller.
HRP20160490T4 (hr) Pripravak i oblik koji sadrže rekombinantnu humanu iduronat-2-sulfatazu te postupci njihove pripreme
WO2010147686A3 (en) Methods of purifying small modular immunopharmaceutical proteins
BR112013017884A2 (pt) varredura de microcolônia encapsulada com gel
BR112012033703A2 (pt) polipeptídeo tendo atividade beta-glicosidase e seus usos
JP2007175057A5 (show.php)
WO2010057203A3 (en) Hdl particles for delivery of nucleic acids
DK2343320T3 (da) Anti-gitr-antistoffer og anvendelser deraf
WO2011097381A3 (en) Engineered enzymes with methionine-gamma-lyase enzymes and pharmacological preparations therof
BR112015009201A2 (pt) composição compreendeendo um polipeptídeo recombinante, ácido nucleico codificando o mesmo, célula hospedeira, bem como métodos para produzir uma beta-glucosidase e para hidrolisar um substrato de biomassa lignocelulósica
RU2015112625A (ru) Пептид, применение пептида для лечения сердечно-сосудистых заболеваний, нуклеотидная последовательность, вектор экспрессии, хозяйская клетка, фармацевтическая композиция
JP2015533791A5 (show.php)
HRP20171694T1 (hr) Novi pripravci i postupci
WO2013016724A3 (en) Decarboxylase proteins with high keto-isovalerate decarboxylase activity
JP2014510101A5 (show.php)
BR112012033701A2 (pt) polipeptídeo tendo atividade de degradação de carbohidrato e seus usos
HRP20161009T1 (hr) Modificirani omci kao inhibitor komplementa
WO2011135222A3 (fr) Utilisation de peptides comme transporteurs destines a l'internalisation de molecules d'interet dans des cellules cibles
WO2012170392A3 (en) Shk-based pharmaceutical compositions and methods of manufacturing and using the same
BR112012008655A2 (pt) formulação detergente em dose distinta ou única.
WO2011156252A3 (en) Sulfation of wnt pathway proteins
WO2009108713A3 (en) Topical compositions and methods utilizing peptides containing lipid-modified cysteine-containing peptides
WO2010092109A3 (en) Nucleic acid molecule of a biosynthetic cluster encoding non ribosomal peptide synthases and uses thereof