JP2015521627A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2015521627A5 JP2015521627A5 JP2015518628A JP2015518628A JP2015521627A5 JP 2015521627 A5 JP2015521627 A5 JP 2015521627A5 JP 2015518628 A JP2015518628 A JP 2015518628A JP 2015518628 A JP2015518628 A JP 2015518628A JP 2015521627 A5 JP2015521627 A5 JP 2015521627A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- sequence number
- referred
- sequence
- chain variable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261662910P | 2012-06-21 | 2012-06-21 | |
| US61/662,910 | 2012-06-21 | ||
| PCT/US2013/047190 WO2013192594A2 (en) | 2012-06-21 | 2013-06-21 | Antigen binding proteins that bind c-met |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018128712A Division JP2018184421A (ja) | 2012-06-21 | 2018-07-06 | c−Metに結合する抗原結合タンパク質 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015521627A JP2015521627A (ja) | 2015-07-30 |
| JP2015521627A5 true JP2015521627A5 (https=) | 2016-08-18 |
| JP6429771B2 JP6429771B2 (ja) | 2018-11-28 |
Family
ID=49769735
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015518628A Expired - Fee Related JP6429771B2 (ja) | 2012-06-21 | 2013-06-21 | c−Metに結合する抗原結合タンパク質 |
| JP2018128712A Withdrawn JP2018184421A (ja) | 2012-06-21 | 2018-07-06 | c−Metに結合する抗原結合タンパク質 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018128712A Withdrawn JP2018184421A (ja) | 2012-06-21 | 2018-07-06 | c−Metに結合する抗原結合タンパク質 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US10377827B2 (https=) |
| EP (1) | EP2863946A4 (https=) |
| JP (2) | JP6429771B2 (https=) |
| CN (2) | CN109503714A (https=) |
| CA (1) | CA2877573A1 (https=) |
| HK (1) | HK1208181A1 (https=) |
| WO (1) | WO2013192594A2 (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013192594A2 (en) | 2012-06-21 | 2013-12-27 | Sorrento Therapeutics Inc. | Antigen binding proteins that bind c-met |
| EA201791203A1 (ru) * | 2014-12-08 | 2018-04-30 | Сорренто Терапьютикс, Инк. | ЛЕКАРСТВЕННЫЙ КОНЪЮГАТ АНТИТЕЛА ПРОТИВ с-МЕТ |
| TWI782930B (zh) | 2016-11-16 | 2022-11-11 | 美商再生元醫藥公司 | 抗met抗體,結合met之雙特異性抗原結合分子及其使用方法 |
| AU2018205484B2 (en) | 2017-01-06 | 2024-11-21 | Sixal, Inc. | Therapeutic anti-lgE antibodies and methods and compositions thereof |
| SG11201907299XA (en) | 2017-02-08 | 2019-09-27 | Dragonfly Therapeutics Inc | Multi-specific binding proteins for activation of natural killer cells and therapeutic uses thereof to treat cancer |
| WO2018148447A1 (en) * | 2017-02-08 | 2018-08-16 | Adimab, Llc | Antibody heavy chain variable domains targeting the nkg2d receptor |
| IL268755B2 (en) | 2017-02-20 | 2025-12-01 | Dragonfly Therapeutics Inc | Proteins that bind her2, nkg2d, and cd16 |
| US20200129633A1 (en) | 2017-06-06 | 2020-04-30 | Jiangsu Hengrui Medicine Co., Ltd. | Pharmaceutical composition comprising c-met antibody-drug conjugate and use thereof |
| EA202091887A1 (ru) | 2018-02-08 | 2020-10-23 | Драгонфлай Терапьютикс, Инк. | Комбинированная терапия рака с применением мультиспецифических связывающих белков, которые активируют естественные клетки-киллеры |
| DK3749346T3 (da) | 2018-02-08 | 2024-09-09 | Dragonfly Therapeutics Inc | Antistof variable domænekombinationer rettet mod nkg2d-receptoren |
| WO2019164930A1 (en) | 2018-02-20 | 2019-08-29 | Dragonfly Therapeutics, Inc. | Multi-specific binding proteins that bind cd33, nkg2d, and cd16, and methods of use |
| EA202091888A1 (ru) | 2018-08-08 | 2020-10-23 | Драгонфлай Терапьютикс, Инк. | Вариабельные домены антител, нацеленные на рецептор nkg2d |
| US12378318B2 (en) | 2018-08-08 | 2025-08-05 | Dragonfly Therapeutics, Inc. | Proteins binding NKG2D, CD16 and a tumor-associated antigen |
| WO2020033630A1 (en) | 2018-08-08 | 2020-02-13 | Dragonfly Therapeutics, Inc. | Multi-specific binding proteins that bind bcma, nkg2d and cd16, and methods of use |
| MX2021005751A (es) * | 2018-11-16 | 2021-10-01 | Memorial Sloan Kettering Cancer Center | Anticuerpos contra mucina 16 y métodos de uso de los mismos. |
| EP3880700B1 (en) * | 2018-11-16 | 2025-12-17 | R.G.C.C. Holdings AG | C-met and tmx2 antibodies |
| US11896682B2 (en) | 2019-09-16 | 2024-02-13 | Regeneron Pharmaceuticals, Inc. | Radiolabeled MET binding proteins for immuno-PET imaging and methods of use thereof |
| MX2022013944A (es) | 2020-05-06 | 2022-11-30 | Dragonfly Therapeutics Inc | Proteinas que se unen al receptor activador de celulas asesinas naturales grupo 2 miembro d (nkg2d), cumulo de diferenciacion (cd16) y miembro a de la familia de dominios de lectina tipo c 12 (clec12a). |
| CN112592408B (zh) * | 2020-07-20 | 2021-08-17 | 北京鼎成肽源生物技术有限公司 | 一种靶向c-Met的单链抗体、嵌合抗原受体、重组载体、CAR-T细胞及应用 |
| EP4259180A4 (en) * | 2020-12-14 | 2024-11-20 | Vanderbilt University | HUMANIZED MONOCLONAL ANTIBODIES DIRECTED AGAINST IGE BINDING TO ALPHA-GAL (GALACTOSE-?-1,3-GALACTOSE) AND THEIR USES |
| JP2024508894A (ja) | 2021-03-03 | 2024-02-28 | ドラゴンフライ セラピューティクス, インコーポレイテッド | Nkg2d、cd16、及び腫瘍関連抗原に結合する多特異性結合タンパク質を使用して癌を治療する方法 |
Family Cites Families (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL154598B (nl) | 1970-11-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking. |
| US3901654A (en) | 1971-06-21 | 1975-08-26 | Biological Developments | Receptor assays of biologically active compounds employing biologically specific receptors |
| US3817827A (en) | 1972-03-30 | 1974-06-18 | Scott Paper Co | Soft absorbent fibrous webs containing elastomeric bonding material and formed by creping and embossing |
| US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| US4002531A (en) | 1976-01-22 | 1977-01-11 | Pierce Chemical Company | Modifying enzymes with polyethylene glycol and product produced thereby |
| US4098876A (en) | 1976-10-26 | 1978-07-04 | Corning Glass Works | Reverse sandwich immunoassay |
| JPS6023084B2 (ja) | 1979-07-11 | 1985-06-05 | 味の素株式会社 | 代用血液 |
| US4640835A (en) | 1981-10-30 | 1987-02-03 | Nippon Chemiphar Company, Ltd. | Plasminogen activator derivatives |
| US4496689A (en) | 1983-12-27 | 1985-01-29 | Miles Laboratories, Inc. | Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer |
| DE3675588D1 (de) | 1985-06-19 | 1990-12-20 | Ajinomoto Kk | Haemoglobin, das an ein poly(alkenylenoxid) gebunden ist. |
| US4791192A (en) | 1986-06-26 | 1988-12-13 | Takeda Chemical Industries, Ltd. | Chemically modified protein with polyethyleneglycol |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US6010902A (en) | 1988-04-04 | 2000-01-04 | Bristol-Meyers Squibb Company | Antibody heteroconjugates and bispecific antibodies for use in regulation of lymphocyte activity |
| US5766897A (en) | 1990-06-21 | 1998-06-16 | Incyte Pharmaceuticals, Inc. | Cysteine-pegylated proteins |
| GB9014932D0 (en) | 1990-07-05 | 1990-08-22 | Celltech Ltd | Recombinant dna product and method |
| JP3051145B2 (ja) | 1990-08-28 | 2000-06-12 | 住友製薬株式会社 | 新規なポリエチレングリコール誘導体修飾ペプチド |
| US5582996A (en) | 1990-12-04 | 1996-12-10 | The Wistar Institute Of Anatomy & Biology | Bifunctional antibodies and method of preparing same |
| DE4118120A1 (de) | 1991-06-03 | 1992-12-10 | Behringwerke Ag | Tetravalente bispezifische rezeptoren, ihre herstellung und verwendung |
| WO1994004679A1 (en) | 1991-06-14 | 1994-03-03 | Genentech, Inc. | Method for making humanized antibodies |
| US5281698A (en) | 1991-07-23 | 1994-01-25 | Cetus Oncology Corporation | Preparation of an activated polymer ester for protein conjugation |
| JPH05244982A (ja) | 1991-12-06 | 1993-09-24 | Sumitomo Chem Co Ltd | 擬人化b−b10 |
| AU673190B2 (en) | 1992-07-13 | 1996-10-31 | Bionebraska, Inc. | Method for modification of recombinant polypeptides |
| US5382657A (en) | 1992-08-26 | 1995-01-17 | Hoffmann-La Roche Inc. | Peg-interferon conjugates |
| ATE240394T1 (de) | 1992-10-23 | 2003-05-15 | Immunex Corp | Methoden zur herstellung löslicher, oligomerer proteine |
| US5446090A (en) | 1993-11-12 | 1995-08-29 | Shearwater Polymers, Inc. | Isolatable, water soluble, and hydrolytically stable active sulfones of poly(ethylene glycol) and related polymers for modification of surfaces and molecules |
| US5932462A (en) | 1995-01-10 | 1999-08-03 | Shearwater Polymers, Inc. | Multiarmed, monofunctional, polymer for coupling to molecules and surfaces |
| US5731168A (en) | 1995-03-01 | 1998-03-24 | Genentech, Inc. | Method for making heteromultimeric polypeptides |
| US5686292A (en) | 1995-06-02 | 1997-11-11 | Genentech, Inc. | Hepatocyte growth factor receptor antagonist antibodies and uses thereof |
| GB9722131D0 (en) | 1997-10-20 | 1997-12-17 | Medical Res Council | Method |
| EP1105427A2 (en) | 1998-08-17 | 2001-06-13 | Abgenix, Inc. | Generation of modified molecules with increased serum half-lives |
| GB9928787D0 (en) | 1999-12-03 | 2000-02-02 | Medical Res Council | Direct screening method |
| US7052686B2 (en) | 2000-09-29 | 2006-05-30 | Schering Corporation | Pegylated interleukin-10 |
| GB0025144D0 (en) | 2000-10-13 | 2000-11-29 | Medical Res Council | Concatenated nucleic acid sequences |
| WO2004072117A2 (en) | 2003-02-13 | 2004-08-26 | Pharmacia Corporation | Antibodies to c-met for the treatment of cancers |
| US20040202995A1 (en) | 2003-04-09 | 2004-10-14 | Domantis | Nucleic acids, proteins, and screening methods |
| HN2004000285A (es) * | 2003-08-04 | 2006-04-27 | Pfizer Prod Inc | ANTICUERPOS DIRIGIDOS A c-MET |
| EP1773885B1 (en) | 2004-08-05 | 2010-04-21 | Genentech, Inc. | Humanized anti-cmet antagonists |
| UA97096C2 (ru) * | 2005-08-31 | 2012-01-10 | Емджен Інк. | Выделенное антитело, которое специфически связывает рецептор-2 trail (tr-2) |
| PE20071101A1 (es) | 2005-08-31 | 2007-12-21 | Amgen Inc | Polipeptidos y anticuerpos |
| CA2638889C (en) * | 2006-02-06 | 2015-06-02 | Metheresis Translational Research S.A. | Anti-met monoclonal antibody, fragments and vectors thereof, for the treatment of tumors and corresponding products |
| EP2004693B1 (en) * | 2006-03-30 | 2012-06-06 | Novartis AG | Compositions and methods of use for antibodies of c-met |
| EP2975057A1 (en) * | 2006-07-10 | 2016-01-20 | Fujita Health University | Novel anti-cd73 antibody |
| EP2014681A1 (en) | 2007-07-12 | 2009-01-14 | Pierre Fabre Medicament | Novel antibodies inhibiting c-met dimerization, and uses thereof |
| PA8849001A1 (es) * | 2008-11-21 | 2010-06-28 | Lilly Co Eli | Anticuerpos de c-met |
| AR074439A1 (es) | 2008-12-02 | 2011-01-19 | Pf Medicament | Anticuerpo anti-cmet (receptor c-met) |
| US8545839B2 (en) * | 2008-12-02 | 2013-10-01 | Pierre Fabre Medicament | Anti-c-Met antibody |
| EP2287197A1 (en) * | 2009-08-21 | 2011-02-23 | Pierre Fabre Medicament | Anti-cMET antibody and its use for the detection and the diagnosis of cancer |
| EP3511342B1 (en) * | 2010-03-10 | 2024-01-17 | Genmab A/S | Monoclonal antibodies against c-met |
| KR20140019284A (ko) * | 2010-09-03 | 2014-02-14 | 아카데미아 시니카 | 항-C-Met 항체 및 이의 이용 방법들 |
| KR101865223B1 (ko) * | 2011-10-05 | 2018-06-08 | 삼성전자주식회사 | 항 c-Met 인간화 항체 및 그의 용도 |
| WO2013192594A2 (en) | 2012-06-21 | 2013-12-27 | Sorrento Therapeutics Inc. | Antigen binding proteins that bind c-met |
| HK1208236A1 (en) * | 2012-06-22 | 2016-02-26 | Sorrento Therapeutics, Inc. | Antigen binding proteins that bind ccr2 |
-
2013
- 2013-06-21 WO PCT/US2013/047190 patent/WO2013192594A2/en not_active Ceased
- 2013-06-21 HK HK15108908.7A patent/HK1208181A1/xx unknown
- 2013-06-21 CN CN201811232378.9A patent/CN109503714A/zh active Pending
- 2013-06-21 CA CA2877573A patent/CA2877573A1/en not_active Abandoned
- 2013-06-21 EP EP13806086.8A patent/EP2863946A4/en not_active Withdrawn
- 2013-06-21 US US13/924,492 patent/US10377827B2/en active Active
- 2013-06-21 JP JP2015518628A patent/JP6429771B2/ja not_active Expired - Fee Related
- 2013-06-21 CN CN201380043630.0A patent/CN105050618B/zh not_active Expired - Fee Related
-
2018
- 2018-07-06 JP JP2018128712A patent/JP2018184421A/ja not_active Withdrawn
-
2019
- 2019-06-25 US US16/451,511 patent/US11155628B2/en not_active Expired - Fee Related
-
2021
- 2021-09-22 US US17/482,140 patent/US20220002422A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2015521627A5 (https=) | ||
| JP2021054859A5 (https=) | ||
| JP2021102633A5 (https=) | ||
| JP2018510151A5 (https=) | ||
| JP2020063262A5 (https=) | ||
| JP2016537383A5 (https=) | ||
| JP2017504577A5 (https=) | ||
| HRP20220131T1 (hr) | Nova terapija s t-staničnim receptorima i imunološka terapija koja koristi iste | |
| JP2017531028A5 (https=) | ||
| RU2018133708A (ru) | Антитела, обладающие специфичностью к btla, и их использование | |
| BR112017009264A2 (pt) | proteína de ligação a epítopo ou um fragmento da mesma e imunoglobulina heterodimérica ou um fragmento da mesma | |
| HK1207398A1 (en) | Cd3 binding polypeptides | |
| JP2018504105A5 (https=) | ||
| JP2014530009A5 (https=) | ||
| JP2020533016A5 (https=) | ||
| JP2013515508A5 (https=) | ||
| FI3683235T3 (fi) | Anti-IL-33-vasta-aineita ja niiden käyttöjä | |
| JP2016536322A5 (https=) | ||
| JP2013527761A5 (https=) | ||
| WO2008053330A3 (en) | Monoclonal antibodies against the human anti-mullerian hormone type ii receptor (amhr-ii) | |
| EA201070539A1 (ru) | НОВЫЕ АНТИТЕЛА, СПЕЦИФИЧНЫЕ К β-АМИЛОИДНЫМ ПЕПТИДАМ, И ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ ДИАГНОСТИЧЕСКИХ ИЛИ ЛЕКАРСТВЕННЫХ СРЕДСТВ | |
| JP2018510865A5 (https=) | ||
| JP2021500376A5 (https=) | ||
| PH12022551231A1 (en) | Polypeptides comprising immunoglobulin single variable domains targeting tnfa and ox40l | |
| EA201790816A1 (ru) | Антитела, которые связываются с ccr6, и варианты применения указанных антител |