JP2021500376A5 - - Google Patents
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- JP2021500376A5 JP2021500376A5 JP2020523261A JP2020523261A JP2021500376A5 JP 2021500376 A5 JP2021500376 A5 JP 2021500376A5 JP 2020523261 A JP2020523261 A JP 2020523261A JP 2020523261 A JP2020523261 A JP 2020523261A JP 2021500376 A5 JP2021500376 A5 JP 2021500376A5
- Authority
- JP
- Japan
- Prior art keywords
- disease
- binder
- seq
- cancer
- directed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024006108A JP2024041975A (ja) | 2017-10-25 | 2024-01-18 | 特定のｄｐｐ３エピトープに指向され、そしてそれに結合するｄｐｐ３バインダー、ならびに酸化ストレスに関連する疾患／急性病態の予防または治療におけるその使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17198420 | 2017-10-25 | ||
| EP17198420.6 | 2017-10-25 | ||
| PCT/EP2018/079197 WO2019081595A2 (en) | 2017-10-25 | 2018-10-24 | DPP3 BINDER DIRECTED TO AND BINDING SPECIFIC DPP3 EPITOPES AND USE THEREOF IN THE PREVENTION OR TREATMENT OF OXIDATIVE STRESS ASSOCIATED DISEASES / CONDITIONS |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024006108A Division JP2024041975A (ja) | 2017-10-25 | 2024-01-18 | 特定のｄｐｐ３エピトープに指向され、そしてそれに結合するｄｐｐ３バインダー、ならびに酸化ストレスに関連する疾患／急性病態の予防または治療におけるその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021500376A JP2021500376A (ja) | 2021-01-07 |
| JP2021500376A5 true JP2021500376A5 (https=) | 2021-11-25 |
| JP7424972B2 JP7424972B2 (ja) | 2024-01-30 |
Family
ID=60186108
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020523261A Active JP7424972B2 (ja) | 2017-10-25 | 2018-10-24 | 特定のｄｐｐ３エピトープに指向され、そしてそれに結合するｄｐｐ３バインダー、ならびに酸化ストレスに関連する疾患／急性病態の予防または治療におけるその使用 |
| JP2024006108A Pending JP2024041975A (ja) | 2017-10-25 | 2024-01-18 | 特定のｄｐｐ３エピトープに指向され、そしてそれに結合するｄｐｐ３バインダー、ならびに酸化ストレスに関連する疾患／急性病態の予防または治療におけるその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024006108A Pending JP2024041975A (ja) | 2017-10-25 | 2024-01-18 | 特定のｄｐｐ３エピトープに指向され、そしてそれに結合するｄｐｐ３バインダー、ならびに酸化ストレスに関連する疾患／急性病態の予防または治療におけるその使用 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US11530276B2 (https=) |
| EP (2) | EP4527458A3 (https=) |
| JP (2) | JP7424972B2 (https=) |
| KR (2) | KR102835427B1 (https=) |
| CN (2) | CN111542548B (https=) |
| AU (2) | AU2018356441C1 (https=) |
| BR (1) | BR112020006563A2 (https=) |
| CA (1) | CA3080251A1 (https=) |
| IL (1) | IL274009B2 (https=) |
| MX (1) | MX2020004271A (https=) |
| MY (1) | MY202502A (https=) |
| SG (1) | SG11202002594PA (https=) |
| WO (1) | WO2019081595A2 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102835427B1 (ko) * | 2017-10-25 | 2025-07-21 | 4틴4 파마슈티컬스 게엠베하 | 특이적 dpp3-에피토프에 대하여 지시되고 이에 결합하는 dpp3 결합제 및 산화적 스트레스와 연관되는 질환 / 급성 병태의 예방 또는 치료에서의 그의 용도 |
| CN113557031A (zh) * | 2018-12-21 | 2021-10-26 | 4Teen4制药有限公司 | 使用血管紧张肽受体激动剂和/或其前体的治疗的疗法指导和/或疗法监测 |
| JP2022546061A (ja) * | 2019-08-30 | 2022-11-02 | ４ティーン４ ファーマシューティカルズ ゲゼルシャフト ミット ベシュレンクテル ハフツング | ショック症治療のための治療法の誘導および／または治療法の監視 |
| US20230193348A1 (en) * | 2020-02-27 | 2023-06-22 | 4TEEN4 Pharmaceuticals GmbH | Dpp3 for therapy guidance, monitoring and stratification of nt-adm antibodies in patients with shock |
| EP3922993A1 (en) | 2020-06-12 | 2021-12-15 | 4TEEN4 Pharmaceuticals GmbH | Dpp3 in patients infected with coronavirus |
| BR112022017277A2 (pt) * | 2020-03-16 | 2022-10-18 | 4TEEN4 Pharmaceuticals GmbH | Dpp3 em pacientes infectados com coronavírus |
| JP2025541138A (ja) | 2022-12-15 | 2025-12-18 | ４ティーン４ ファーマシューティカルズ ゲゼルシャフト ミット ベシュレンクテル ハフツング | 重篤な患者における肺機能の改善のためのｄｐｐ３阻害剤 |
| CN115804836A (zh) * | 2022-12-27 | 2023-03-17 | 中国人民解放军海军特色医学中心 | 一种中枢小分子蛋白dpp3在制备降压药物中的应用 |
| EP4687942A1 (en) | 2023-03-29 | 2026-02-11 | 4TEEN4 Pharmaceuticals GmbH | Dpp3 inhibitor for myocardial protection and prevention of myocardial injury in critically ill patients with blood pressure decline |
| WO2026046947A1 (en) | 2024-08-26 | 2026-03-05 | 4TEEN4 Pharmaceuticals GmbH | Anti-dpp3 antibody directed to and binding to dpp3 for the treatment of shock in extreme-critically ill patients |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5807715A (en) | 1984-08-27 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin |
| JPS6188884A (ja) | 1984-10-04 | 1986-05-07 | Sankyo Co Ltd | エンケフアリナ−ゼｂ阻害物質およびその製法 |
| AU634716B2 (en) | 1988-08-01 | 1993-03-04 | Ciba Corning Diagnostics Corp. | Method for detection of an analyte using acridinium esters and liposomes |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| DE69120146T2 (de) | 1990-01-12 | 1996-12-12 | Cell Genesys Inc | Erzeugung xenogener antikörper |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| DK0585287T3 (da) | 1990-07-10 | 2000-04-17 | Cambridge Antibody Tech | Fremgangsmåde til fremstilling af specifikke bindingsparelementer |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| WO1993012227A1 (en) | 1991-12-17 | 1993-06-24 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US6818418B1 (en) | 1998-12-10 | 2004-11-16 | Compound Therapeutics, Inc. | Protein scaffolds for antibody mimics and other binding proteins |
| WO2001016334A2 (en) | 1999-09-01 | 2001-03-08 | Incyte Genomics, Inc. | Human hydrolytic enzymes |
| AU2002323501C1 (en) | 2001-08-30 | 2010-04-29 | Biorexis Technology, Inc | Modified transferrin fusion proteins |
| ES2348230T3 (es) | 2002-06-07 | 2010-12-01 | Dyax Corp. | Prevención y reducción de la isquemia. |
| US20050164301A1 (en) | 2003-10-24 | 2005-07-28 | Avidia Research Institute | LDL receptor class A and EGF domain monomers and multimers |
| US20100028995A1 (en) | 2004-02-23 | 2010-02-04 | Anaphore, Inc. | Tetranectin Trimerizing Polypeptides |
| WO2005106486A2 (en) * | 2004-04-28 | 2005-11-10 | Bayer Healthcare Ag | Diagnostic and therapeutics for diseases associated with dipeptidyl-peptidase 3(dpp3) |
| AU2005287557B2 (en) | 2004-09-21 | 2011-10-13 | Biontech Ag | Use of microproteins as tryptase inhibitors |
| JP2006230318A (ja) | 2005-02-25 | 2006-09-07 | Maruishi Pharmaceutical Co Ltd | 関節リウマチの診断方法 |
| WO2007117444A2 (en) | 2006-03-31 | 2007-10-18 | Yinghe Hu | Protein detection by aptamers |
| US20080057590A1 (en) | 2006-06-07 | 2008-03-06 | Mickey Urdea | Markers associated with arteriovascular events and methods of use thereof |
| ES2373832T3 (es) | 2007-12-19 | 2012-02-09 | Affibody Ab | Polipéptido derivado de proteína a y capaz de unirse a pdgf. |
| BRPI0921469B1 (pt) | 2008-11-03 | 2022-01-18 | Molecular Partners Ag | Proteínas de ligação que inibem a interação com o receptor de vegf-a, composição farmacêutica |
| WO2010093872A2 (en) | 2009-02-13 | 2010-08-19 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Molecular-based method of cancer diagnosis and prognosis |
| DK2414542T3 (da) * | 2009-03-30 | 2017-11-27 | Tel Hashomer Medical Res Infrastructure & Services Ltd | Fremgangsmåder til forudsigelse af klinisk forløb for og behandling af multipel sklerose |
| MX2012002428A (es) | 2009-08-27 | 2012-09-12 | Covagen Ag | Compuestos de union il-17 y usos medicos de los mismos. |
| RU2553333C2 (ru) | 2009-12-14 | 2015-06-10 | Сцил Протеинс Гмбх | Способ идентификации гетеромультимерных модифицированных убиквитиновых белков со способностью связываться с лигандами |
| PL2580236T3 (pl) | 2010-06-08 | 2019-09-30 | Pieris Pharmaceuticals Gmbh | Muteiny lipokaliny łez wiążące IL-4 R alfa |
| MX2015009403A (es) | 2013-01-28 | 2017-07-04 | Nuevas Alternativas Naturales Thermafat S A P I De C V | Composiciones para tratamiento sistemico de condiciones patologicas resultantes de estres oxidativo y/o desequilibrio redox. |
| CN104946646B (zh) * | 2014-03-25 | 2020-03-31 | 中国医学科学院基础医学研究所 | 用于预防和/或治疗埃博拉病毒性出血热的小核酸分子、dna分子、蛋白及应用 |
| DE112017002105T5 (de) | 2016-04-21 | 2019-04-25 | Sphingotec Therapeutics Gmbh | Verfahren zur Bestimmung von DPP3 und therapeutische Verfahren |
| KR102835427B1 (ko) * | 2017-10-25 | 2025-07-21 | 4틴4 파마슈티컬스 게엠베하 | 특이적 dpp3-에피토프에 대하여 지시되고 이에 결합하는 dpp3 결합제 및 산화적 스트레스와 연관되는 질환 / 급성 병태의 예방 또는 치료에서의 그의 용도 |
-
2018
- 2018-10-24 KR KR1020207014841A patent/KR102835427B1/ko active Active
- 2018-10-24 EP EP25153152.1A patent/EP4527458A3/en active Pending
- 2018-10-24 IL IL274009A patent/IL274009B2/en unknown
- 2018-10-24 KR KR1020257023507A patent/KR20250111243A/ko active Pending
- 2018-10-24 EP EP18795970.5A patent/EP3700937A2/en active Pending
- 2018-10-24 MX MX2020004271A patent/MX2020004271A/es unknown
- 2018-10-24 US US16/758,881 patent/US11530276B2/en active Active
- 2018-10-24 CN CN201880069013.0A patent/CN111542548B/zh active Active
- 2018-10-24 WO PCT/EP2018/079197 patent/WO2019081595A2/en not_active Ceased
- 2018-10-24 CA CA3080251A patent/CA3080251A1/en active Pending
- 2018-10-24 AU AU2018356441A patent/AU2018356441C1/en active Active
- 2018-10-24 BR BR112020006563-3A patent/BR112020006563A2/pt unknown
- 2018-10-24 MY MYPI2020002078A patent/MY202502A/en unknown
- 2018-10-24 JP JP2020523261A patent/JP7424972B2/ja active Active
- 2018-10-24 SG SG11202002594PA patent/SG11202002594PA/en unknown
- 2018-10-24 CN CN202410933184.0A patent/CN118791621A/zh active Pending
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2022
- 2022-11-10 US US17/984,611 patent/US20230295344A1/en active Pending
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2024
- 2024-01-18 JP JP2024006108A patent/JP2024041975A/ja active Pending
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2025
- 2025-03-06 AU AU2025201656A patent/AU2025201656A1/en active Pending