PL2097453T3 - Przeciwciała monoklonalne przeciw ludzkiemu receptorowi hormonu anty-Mullerowskiego typu II (AMHR-II) - Google Patents

Przeciwciała monoklonalne przeciw ludzkiemu receptorowi hormonu anty-Mullerowskiego typu II (AMHR-II)

Info

Publication number
PL2097453T3
PL2097453T3 PL07848842T PL07848842T PL2097453T3 PL 2097453 T3 PL2097453 T3 PL 2097453T3 PL 07848842 T PL07848842 T PL 07848842T PL 07848842 T PL07848842 T PL 07848842T PL 2097453 T3 PL2097453 T3 PL 2097453T3
Authority
PL
Poland
Prior art keywords
amhr
receptor
monoclonal antibodies
human anti
antibodies against
Prior art date
Application number
PL07848842T
Other languages
English (en)
Inventor
Isabelle Teulon
André Pelegrin
Original Assignee
Inst Nat Sante Rech Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Nat Sante Rech Med filed Critical Inst Nat Sante Rech Med
Publication of PL2097453T3 publication Critical patent/PL2097453T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2869Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against hormone receptors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575Hormones
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Neurology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Reproductive Health (AREA)
  • Food Science & Technology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PL07848842T 2006-11-02 2007-10-31 Przeciwciała monoklonalne przeciw ludzkiemu receptorowi hormonu anty-Mullerowskiego typu II (AMHR-II) PL2097453T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06291703A EP1918304A1 (en) 2006-11-02 2006-11-02 Monoclonal antibodies against the human anti-müllerian hormone type II receptor (AMHR-II)
EP07848842A EP2097453B1 (en) 2006-11-02 2007-10-31 Monoclonal antibodies against the human anti-müllerian hormone type ii receptor (amhr-ii)
PCT/IB2007/003301 WO2008053330A2 (en) 2006-11-02 2007-10-31 Monoclonal antibodies against the human anti-mullerian hormone type ii receptor (amhr-ii)

Publications (1)

Publication Number Publication Date
PL2097453T3 true PL2097453T3 (pl) 2011-09-30

Family

ID=37763855

Family Applications (1)

Application Number Title Priority Date Filing Date
PL07848842T PL2097453T3 (pl) 2006-11-02 2007-10-31 Przeciwciała monoklonalne przeciw ludzkiemu receptorowi hormonu anty-Mullerowskiego typu II (AMHR-II)

Country Status (12)

Country Link
US (2) US8278423B2 (pl)
EP (2) EP1918304A1 (pl)
JP (3) JP2010508810A (pl)
KR (2) KR101686000B1 (pl)
CN (2) CN101573382B (pl)
AT (1) ATE502052T1 (pl)
CA (1) CA2667970C (pl)
DE (1) DE602007013282D1 (pl)
DK (1) DK2097453T3 (pl)
ES (1) ES2363732T3 (pl)
PL (1) PL2097453T3 (pl)
WO (1) WO2008053330A2 (pl)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1918304A1 (en) * 2006-11-02 2008-05-07 Institut National De La Sante Et De La Recherche Medicale (Inserm) Monoclonal antibodies against the human anti-müllerian hormone type II receptor (AMHR-II)
JP5565723B2 (ja) * 2009-04-07 2014-08-06 学校法人北里研究所 抗dcdモノクローナル抗体
WO2011045202A1 (en) * 2009-10-12 2011-04-21 INSERM (Institut National de la Santé et de la Recherche Médicale) Selective antagonist or agonist of amhrii for modulating fertility
FR2959994B1 (fr) * 2010-05-12 2012-08-24 Lfb Biotechnologies Nouveaux anticorps humanises 12g4 mutes et leurs fragments diriges contre le recepteur humain de l'hormone anti-mullerienne de type ii
WO2012166712A1 (en) * 2011-05-27 2012-12-06 Fox Chase Cancer Center Rationally-designed anti-mullerian inhibiting substance type ii receptor antibodies
FR2984750B1 (fr) * 2011-12-23 2014-01-10 Lfb Biotechnologies Nouvelles compositions pharmaceutiques comprenant un anticorps liant le recepteur humain de l'hormone anti-mullerienne de type ii
ITRM20130455A1 (it) * 2013-08-05 2015-02-06 Alfonso Baldi Ligandi dell'ormone anti-mulleriano
CN104865391B (zh) * 2015-05-06 2016-06-22 薛金锋 人抗苗勒激素的酶联免疫检测试剂
EP3331569A1 (en) 2015-08-07 2018-06-13 Gamamabs Pharma Antibodies, antibody drug conjugates and methods of use
ES2865378T3 (es) * 2015-09-02 2021-10-15 Cleveland Clinic Found Vacunas contra el cáncer de ovario
EP3464354B1 (en) * 2016-06-02 2021-07-28 Bloom Diagnostics AG Antibodies that bind to human anti-müllerian hormone (amh) and their uses
EP3490611A4 (en) * 2016-07-26 2020-04-15 Trustees Of Tufts College ANTIBODY-CONJUGATED NANOPARTICLES AND MEDICAL USES THEREOF
FR3060394B1 (fr) 2016-12-16 2019-05-24 Laboratoire Francais Du Fractionnement Et Des Biotechnologies Combinaison d'anticorps anti-cd303 et anti-amhrii
BR112019021472A8 (pt) * 2017-04-14 2023-05-02 Inst Curie Compostos de ligação ao amhrii para prevenção ou tratamento de cânceres
JP7289420B6 (ja) * 2017-04-14 2023-06-30 エクセリクシス, インク. 肺癌を予防又は処置する為のamhrii結合性化合物
CN110531077B (zh) * 2018-05-25 2023-07-07 荣昌生物制药(烟台)股份有限公司 间皮素免疫组化检测试剂盒
WO2020051275A1 (en) * 2018-09-05 2020-03-12 The Board Of Regents Of The University Of Texas System Monoclonal antibodies against endotrophin and the use thereof
WO2020186158A2 (en) * 2019-03-13 2020-09-17 Ulmert Hans David Staffan Prame binding molecules and uses thereof
EP3789401A1 (en) 2019-09-03 2021-03-10 Gamamabs Pharma Amhrii-binding antibody drug conjugates and their use thereof in the treatment of cancers
EP4034560A1 (en) * 2019-09-27 2022-08-03 INSERM (Institut National de la Santé et de la Recherche Médicale) Anti-müllerian inhibiting substance antibodies and uses thereof
EP3812008A1 (en) * 2019-10-23 2021-04-28 Gamamabs Pharma Amh-competitive antagonist antibody
EP4097143A1 (en) * 2020-01-31 2022-12-07 The Cleveland Clinic Foundation Anti-müllerian hormone receptor 2 antibodies and methods of use
CN112251444B (zh) * 2020-10-21 2023-05-16 恺佧生物科技(上海)有限公司 一种改造的amh基因序列及利用其制备amh的方法
CA3207359A1 (en) 2021-02-05 2022-08-11 Cecile Chartier-Courtaud Adjuvant therapy for cancer
CN113238057B (zh) * 2021-04-23 2022-10-14 迪瑞医疗科技股份有限公司 苗勒氏管抑制物受体化学发光免疫检测试剂盒及其制备方法
CN118591555A (zh) * 2021-10-08 2024-09-03 上海礼新医药研发有限公司 抗amhrii抗体

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2807767B1 (fr) * 2000-04-12 2005-01-14 Lab Francais Du Fractionnement Anticorps monoclonaux anti-d
JPWO2002078739A1 (ja) * 2001-03-29 2004-07-22 協和醗酵工業株式会社 ガングリオシドgd3に対する遺伝子組換え抗体を含む医薬
US7425328B2 (en) 2003-04-22 2008-09-16 Purdue Pharma L.P. Tissue factor antibodies and uses thereof
WO2005005615A2 (en) * 2003-07-08 2005-01-20 Fox Chase Cancer Center Anti-mullerian inhibiting substance type ii receptor (misiir) immunoconjugates to detect and treat cancer
EP1918304A1 (en) * 2006-11-02 2008-05-07 Institut National De La Sante Et De La Recherche Medicale (Inserm) Monoclonal antibodies against the human anti-müllerian hormone type II receptor (AMHR-II)
JP2013212800A (ja) * 2012-04-03 2013-10-17 Webasto Japan Kk サンルーフのウエザーストリップ構造及びウエザーストリップの取付方法

Also Published As

Publication number Publication date
KR20090101897A (ko) 2009-09-29
EP2097453A2 (en) 2009-09-09
US9458239B2 (en) 2016-10-04
WO2008053330A3 (en) 2008-10-23
CN101573382B (zh) 2013-08-21
JP2014076992A (ja) 2014-05-01
WO2008053330A2 (en) 2008-05-08
KR101686000B1 (ko) 2016-12-14
ES2363732T3 (es) 2011-08-12
CN101573382A (zh) 2009-11-04
US20130164300A1 (en) 2013-06-27
CN103396491A (zh) 2013-11-20
CA2667970C (en) 2016-10-04
US8278423B2 (en) 2012-10-02
JP2016102109A (ja) 2016-06-02
CA2667970A1 (en) 2008-05-08
JP5903717B2 (ja) 2016-04-13
DK2097453T3 (da) 2011-06-27
EP1918304A1 (en) 2008-05-07
ATE502052T1 (de) 2011-04-15
JP2010508810A (ja) 2010-03-25
KR20150036812A (ko) 2015-04-07
EP2097453B1 (en) 2011-03-16
US20100135996A1 (en) 2010-06-03
DE602007013282D1 (de) 2011-04-28

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