JP2015520165A5 - - Google Patents

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Publication number
JP2015520165A5
JP2015520165A5 JP2015512903A JP2015512903A JP2015520165A5 JP 2015520165 A5 JP2015520165 A5 JP 2015520165A5 JP 2015512903 A JP2015512903 A JP 2015512903A JP 2015512903 A JP2015512903 A JP 2015512903A JP 2015520165 A5 JP2015520165 A5 JP 2015520165A5
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JP
Japan
Prior art keywords
salt
compound
formula
process according
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2015512903A
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English (en)
Japanese (ja)
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JP6196294B2 (ja
JP2015520165A (ja
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Priority claimed from PCT/US2013/041687 external-priority patent/WO2013173779A1/en
Publication of JP2015520165A publication Critical patent/JP2015520165A/ja
Publication of JP2015520165A5 publication Critical patent/JP2015520165A5/ja
Application granted granted Critical
Publication of JP6196294B2 publication Critical patent/JP6196294B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2015512903A 2012-05-17 2013-05-17 アミノ酸化合物を製造するためのプロセス Active JP6196294B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261648534P 2012-05-17 2012-05-17
US61/648,534 2012-05-17
PCT/US2013/041687 WO2013173779A1 (en) 2012-05-17 2013-05-17 Process for making amino acid compounds

Publications (3)

Publication Number Publication Date
JP2015520165A JP2015520165A (ja) 2015-07-16
JP2015520165A5 true JP2015520165A5 (enExample) 2016-06-30
JP6196294B2 JP6196294B2 (ja) 2017-09-13

Family

ID=48483247

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015512903A Active JP6196294B2 (ja) 2012-05-17 2013-05-17 アミノ酸化合物を製造するためのプロセス

Country Status (21)

Country Link
US (1) US9278917B2 (enExample)
EP (1) EP2850054B1 (enExample)
JP (1) JP6196294B2 (enExample)
KR (1) KR102074535B1 (enExample)
CN (1) CN104520263B (enExample)
AU (1) AU2013262516B2 (enExample)
BR (1) BR112014028585B1 (enExample)
CA (1) CA2873658C (enExample)
ES (1) ES2668477T3 (enExample)
HR (1) HRP20180948T1 (enExample)
IL (1) IL235630A (enExample)
MA (1) MA37751B1 (enExample)
MX (1) MX350443B (enExample)
MY (1) MY171538A (enExample)
NZ (1) NZ702939A (enExample)
PL (1) PL2850054T3 (enExample)
RU (1) RU2643146C2 (enExample)
SG (1) SG11201407625WA (enExample)
SI (1) SI2850054T1 (enExample)
TR (1) TR201807444T4 (enExample)
WO (1) WO2013173779A1 (enExample)

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Publication number Priority date Publication date Assignee Title
RS60417B9 (sr) 2012-05-17 2021-07-30 Genentech Inc Amorfni oblik aktivnog jedinjenja koje inhibira pirimidinil-ciklopentansko jedinjenje, smeše i njegove metode
ES2588878T3 (es) 2012-05-17 2016-11-07 Array Biopharma, Inc. Proceso para preparar compuestos de ciclopentilpirimidina hidroxilada
AU2013262505B2 (en) 2012-05-17 2017-09-21 Array Biopharma Inc. Process for making hydroxylated cyclopentylpyrimidine compounds
KR102123131B1 (ko) 2012-05-17 2020-06-15 제넨테크, 인크. 하이드록실화 사이클로펜타피리미딘 화합물 및 이의 염의 제조 방법
CN105899492B (zh) 2013-11-15 2021-08-24 豪夫迈·罗氏有限公司 用于制备嘧啶基环戊烷化合物的方法
MA51165A (fr) * 2014-09-26 2020-10-21 Hoffmann La Roche Procédés de préparation de composés de (cyclopentyl[d]pyrimidin-4-yl)pipérazine

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US4663327A (en) * 1984-05-23 1987-05-05 Bayer Aktiengesellschaft 1-heteroaryl-4-aryl-pyrazolin-5-ones
WO1995015684A1 (en) 1993-12-12 1995-06-15 Agrogene, Ltd. A novel method to protect plants from fungal infection
JP2001524079A (ja) 1997-04-07 2001-11-27 メルク エンド カンパニー インコーポレーテッド ガンの治療方法
US6201023B1 (en) 1997-06-10 2001-03-13 Agrogene Ltd. Methods and compositions to protect crops against plant parasitic nematodes
EP0982300A3 (en) 1998-07-29 2000-03-08 Societe Civile Bioprojet Non-imidazole alkylamines as histamine H3 - receptor ligands and their therapeutic applications
EP1158982A4 (en) 1999-03-03 2002-06-12 Merck & Co Inc Prenyl protein transferase inhibitors
AU7715300A (en) 1999-09-27 2001-04-30 Merck & Co., Inc. Method of preventing osteoporosis
PE20050630A1 (es) 2003-06-09 2005-09-22 Boehringer Ingelheim Int Compuestos heterociclicos como inhibidores del papiloma virus
FR2892416B1 (fr) * 2005-10-20 2008-06-27 Sanofi Aventis Sa Derives de 6-heteroarylpyridoindolone, leur preparation et leur application en therapeutique
US8927546B2 (en) 2006-02-28 2015-01-06 Dart Neuroscience (Cayman) Ltd. Therapeutic piperazines
US8063050B2 (en) 2006-07-06 2011-11-22 Array Biopharma Inc. Hydroxylated and methoxylated pyrimidyl cyclopentanes as AKT protein kinase inhibitors
UA95641C2 (xx) * 2006-07-06 2011-08-25 Эррей Биофарма Инк. Гідроксильовані піримідильні циклопентани як інгібітори акт протеїнкінази$гидроксилированные пиримидильные циклопентаны как ингибиторы акт протеинкиназы
US20100298289A1 (en) 2007-10-09 2010-11-25 Ucb Pharma, S.A. Heterobicyclic compounds as histamine h4-receptor antagonists
EP2419404B1 (en) 2009-04-15 2015-11-04 AbbVie Inc. Anti-viral compounds
CN102574852B (zh) 2009-10-23 2014-06-25 伊莱利利公司 Akt抑制剂
PT2592933T (pt) 2010-07-16 2017-05-23 Gaweco Anderson Inibidores de mif e suas utilizações
WO2012177925A1 (en) 2011-06-21 2012-12-27 The Board Institute, Inc. Akt inhibitors for treating cancer expressing a magi3 - akt3 fusion gene
ES2588878T3 (es) 2012-05-17 2016-11-07 Array Biopharma, Inc. Proceso para preparar compuestos de ciclopentilpirimidina hidroxilada
KR102123131B1 (ko) 2012-05-17 2020-06-15 제넨테크, 인크. 하이드록실화 사이클로펜타피리미딘 화합물 및 이의 염의 제조 방법
CA2889855A1 (en) 2012-11-01 2014-05-08 Robert S. Katz Methods for treating fibromyalgia
EP2956441A4 (en) 2013-02-18 2016-11-02 Scripps Research Inst MODULATORS OF VASOPRESSIN RECEPTORS WITH THERAPEUTIC POTENTIAL
US10131637B2 (en) 2013-03-15 2018-11-20 Shifa Biomedical Corporation Anti-PCSK9 compounds and methods for the treatment and/or prevention of cardiovascular diseases

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