IL235630A - Process for making amino acid compounds - Google Patents
Process for making amino acid compoundsInfo
- Publication number
- IL235630A IL235630A IL235630A IL23563014A IL235630A IL 235630 A IL235630 A IL 235630A IL 235630 A IL235630 A IL 235630A IL 23563014 A IL23563014 A IL 23563014A IL 235630 A IL235630 A IL 235630A
- Authority
- IL
- Israel
- Prior art keywords
- amino acid
- acid compounds
- making amino
- making
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C269/06—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups by reactions not involving the formation of carbamate groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/30—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and unsaturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C269/04—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups from amines with formation of carbamate groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/313—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of doubly bound oxygen containing functional groups, e.g. carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/30—Preparation of optical isomers
- C07C227/32—Preparation of optical isomers by stereospecific synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
- C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261648534P | 2012-05-17 | 2012-05-17 | |
| PCT/US2013/041687 WO2013173779A1 (en) | 2012-05-17 | 2013-05-17 | Process for making amino acid compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL235630A0 IL235630A0 (en) | 2015-02-01 |
| IL235630A true IL235630A (en) | 2017-03-30 |
Family
ID=48483247
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL235630A IL235630A (en) | 2012-05-17 | 2014-11-11 | Process for making amino acid compounds |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US9278917B2 (enExample) |
| EP (1) | EP2850054B1 (enExample) |
| JP (1) | JP6196294B2 (enExample) |
| KR (1) | KR102074535B1 (enExample) |
| CN (1) | CN104520263B (enExample) |
| AU (1) | AU2013262516B2 (enExample) |
| BR (1) | BR112014028585B1 (enExample) |
| CA (1) | CA2873658C (enExample) |
| ES (1) | ES2668477T3 (enExample) |
| HR (1) | HRP20180948T1 (enExample) |
| IL (1) | IL235630A (enExample) |
| MA (1) | MA37751B1 (enExample) |
| MX (1) | MX350443B (enExample) |
| MY (1) | MY171538A (enExample) |
| NZ (1) | NZ702939A (enExample) |
| PL (1) | PL2850054T3 (enExample) |
| RU (1) | RU2643146C2 (enExample) |
| SG (1) | SG11201407625WA (enExample) |
| SI (1) | SI2850054T1 (enExample) |
| TR (1) | TR201807444T4 (enExample) |
| WO (1) | WO2013173779A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9416110B2 (en) | 2012-05-17 | 2016-08-16 | Array Biopharma Inc. | Process for making hydroxylated cyclopentylpyrimidine compounds |
| MY170086A (en) | 2012-05-17 | 2019-07-04 | Genentech Inc | Amorphous form of an akt inhibiting pyrimidinyl - cyclopentane compound, compositions and methods thereof |
| CA2873653A1 (en) | 2012-05-17 | 2013-11-21 | Array Biopharma Inc. | Process for making hydroxylated cyclopentylpyrimidine compounds |
| SG11201407591PA (en) | 2012-05-17 | 2015-01-29 | Genentech Inc | Process of making hydroxylated cyclopentapyrimidine compounds and salts thereof |
| HRP20231100T1 (hr) | 2013-11-15 | 2023-12-22 | F. Hoffmann - La Roche Ag | Postupci za proizvodnju pirimidinilciklopentan spojeva |
| MX368298B (es) * | 2014-09-26 | 2019-09-27 | Hoffmann La Roche | Procesos para preparar compuestos de (ciclopentil [d]pirimidin-4-il)piperazina. |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4663327A (en) * | 1984-05-23 | 1987-05-05 | Bayer Aktiengesellschaft | 1-heteroaryl-4-aryl-pyrazolin-5-ones |
| EP0732874A4 (en) | 1993-12-12 | 1998-10-07 | Agrogene Ltd | METHOD FOR PROTECTING PLANTS FROM MUSHROOM INFECTION |
| JP2001524079A (ja) | 1997-04-07 | 2001-11-27 | メルク エンド カンパニー インコーポレーテッド | ガンの治療方法 |
| US6201023B1 (en) | 1997-06-10 | 2001-03-13 | Agrogene Ltd. | Methods and compositions to protect crops against plant parasitic nematodes |
| EP0982300A3 (en) | 1998-07-29 | 2000-03-08 | Societe Civile Bioprojet | Non-imidazole alkylamines as histamine H3 - receptor ligands and their therapeutic applications |
| JP2003524618A (ja) | 1999-03-03 | 2003-08-19 | メルク エンド カムパニー インコーポレーテッド | プレニル蛋白トランスフェラーゼ阻害剤 |
| AU7715300A (en) | 1999-09-27 | 2001-04-30 | Merck & Co., Inc. | Method of preventing osteoporosis |
| PE20050630A1 (es) | 2003-06-09 | 2005-09-22 | Boehringer Ingelheim Int | Compuestos heterociclicos como inhibidores del papiloma virus |
| FR2892416B1 (fr) * | 2005-10-20 | 2008-06-27 | Sanofi Aventis Sa | Derives de 6-heteroarylpyridoindolone, leur preparation et leur application en therapeutique |
| US8927546B2 (en) | 2006-02-28 | 2015-01-06 | Dart Neuroscience (Cayman) Ltd. | Therapeutic piperazines |
| US8063050B2 (en) | 2006-07-06 | 2011-11-22 | Array Biopharma Inc. | Hydroxylated and methoxylated pyrimidyl cyclopentanes as AKT protein kinase inhibitors |
| UA95641C2 (xx) | 2006-07-06 | 2011-08-25 | Эррей Биофарма Инк. | Гідроксильовані піримідильні циклопентани як інгібітори акт протеїнкінази$гидроксилированные пиримидильные циклопентаны как ингибиторы акт протеинкиназы |
| WO2009047255A1 (en) | 2007-10-09 | 2009-04-16 | Ucb Pharma, S.A. | Heterobicyclic compounds as histamine h4-receptor antagonists |
| RU2541571C2 (ru) | 2009-04-15 | 2015-02-20 | Эббви Инк. | Противовирусные соединения |
| EP2491032B1 (en) | 2009-10-23 | 2014-04-16 | Eli Lilly and Company | Akt inhibitors |
| WO2012009649A1 (en) | 2010-07-16 | 2012-01-19 | Anderson Gaweco | Mif inhibitors and their uses |
| WO2012177925A1 (en) | 2011-06-21 | 2012-12-27 | The Board Institute, Inc. | Akt inhibitors for treating cancer expressing a magi3 - akt3 fusion gene |
| CA2873653A1 (en) | 2012-05-17 | 2013-11-21 | Array Biopharma Inc. | Process for making hydroxylated cyclopentylpyrimidine compounds |
| SG11201407591PA (en) | 2012-05-17 | 2015-01-29 | Genentech Inc | Process of making hydroxylated cyclopentapyrimidine compounds and salts thereof |
| WO2014071194A2 (en) | 2012-11-01 | 2014-05-08 | Katz Robert S | Methods for treating fibromyalgia |
| CN105263910A (zh) | 2013-02-18 | 2016-01-20 | 斯克利普斯研究所 | 具有治疗潜力的血管加压素受体调节剂 |
| WO2014150395A1 (en) | 2013-03-15 | 2014-09-25 | Shifa Biomedical Corporation | Anti-pcsk9 compounds and methods for the treatment and/or prevention of cardiovascular diseases |
-
2013
- 2013-05-17 CN CN201380037572.0A patent/CN104520263B/zh active Active
- 2013-05-17 BR BR112014028585-3A patent/BR112014028585B1/pt active IP Right Grant
- 2013-05-17 MX MX2014013863A patent/MX350443B/es active IP Right Grant
- 2013-05-17 EP EP13724711.0A patent/EP2850054B1/en active Active
- 2013-05-17 WO PCT/US2013/041687 patent/WO2013173779A1/en not_active Ceased
- 2013-05-17 ES ES13724711.0T patent/ES2668477T3/es active Active
- 2013-05-17 PL PL13724711T patent/PL2850054T3/pl unknown
- 2013-05-17 NZ NZ702939A patent/NZ702939A/en not_active IP Right Cessation
- 2013-05-17 SI SI201331043T patent/SI2850054T1/en unknown
- 2013-05-17 RU RU2014150991A patent/RU2643146C2/ru active
- 2013-05-17 KR KR1020147035263A patent/KR102074535B1/ko active Active
- 2013-05-17 AU AU2013262516A patent/AU2013262516B2/en active Active
- 2013-05-17 US US14/401,095 patent/US9278917B2/en active Active
- 2013-05-17 MY MYPI2014703417A patent/MY171538A/en unknown
- 2013-05-17 TR TR2018/07444T patent/TR201807444T4/tr unknown
- 2013-05-17 MA MA37751A patent/MA37751B1/fr unknown
- 2013-05-17 HR HRP20180948TT patent/HRP20180948T1/hr unknown
- 2013-05-17 JP JP2015512903A patent/JP6196294B2/ja active Active
- 2013-05-17 SG SG11201407625WA patent/SG11201407625WA/en unknown
- 2013-05-17 CA CA2873658A patent/CA2873658C/en active Active
-
2014
- 2014-11-11 IL IL235630A patent/IL235630A/en active IP Right Grant
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed |