JP2015519355A5 - - Google Patents
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- Publication number
- JP2015519355A5 JP2015519355A5 JP2015514499A JP2015514499A JP2015519355A5 JP 2015519355 A5 JP2015519355 A5 JP 2015519355A5 JP 2015514499 A JP2015514499 A JP 2015514499A JP 2015514499 A JP2015514499 A JP 2015514499A JP 2015519355 A5 JP2015519355 A5 JP 2015519355A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- seq
- tlr3
- binding
- tlr3 polypeptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 101000831496 Homo sapiens Toll-like receptor 3 Proteins 0.000 claims 23
- 102100024324 Toll-like receptor 3 Human genes 0.000 claims 20
- 229920001184 polypeptide Polymers 0.000 claims 20
- 102000004196 processed proteins & peptides Human genes 0.000 claims 20
- 108090000765 processed proteins & peptides Proteins 0.000 claims 20
- 125000003275 alpha amino acid group Chemical group 0.000 claims 10
- 230000035772 mutation Effects 0.000 claims 4
- 102000045716 human TLR3 Human genes 0.000 claims 3
- 230000019491 signal transduction Effects 0.000 claims 2
- 102000040650 (ribonucleotides)n+m Human genes 0.000 claims 1
- 108091032973 (ribonucleotides)n+m Proteins 0.000 claims 1
- 208000023275 Autoimmune disease Diseases 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 208000027866 inflammatory disease Diseases 0.000 claims 1
- 230000002757 inflammatory effect Effects 0.000 claims 1
- 230000001404 mediated effect Effects 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 231100000331 toxic Toxicity 0.000 claims 1
- 230000002588 toxic effect Effects 0.000 claims 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261653652P | 2012-05-31 | 2012-05-31 | |
| US61/653,652 | 2012-05-31 | ||
| US201261670289P | 2012-07-11 | 2012-07-11 | |
| US61/670,289 | 2012-07-11 | ||
| US201261679923P | 2012-08-06 | 2012-08-06 | |
| US61/679,923 | 2012-08-06 | ||
| PCT/EP2013/061173 WO2013178736A1 (en) | 2012-05-31 | 2013-05-30 | Tlr3 binding agents |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015519355A JP2015519355A (ja) | 2015-07-09 |
| JP2015519355A5 true JP2015519355A5 (enExample) | 2016-06-02 |
| JP6356120B2 JP6356120B2 (ja) | 2018-07-11 |
Family
ID=48576992
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015514499A Expired - Fee Related JP6356120B2 (ja) | 2012-05-31 | 2013-05-30 | Ｔｌｒ３結合剤 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9944712B2 (enExample) |
| EP (1) | EP2855527B1 (enExample) |
| JP (1) | JP6356120B2 (enExample) |
| CN (1) | CN104379603B (enExample) |
| AU (1) | AU2013269652B2 (enExample) |
| CA (1) | CA2874918A1 (enExample) |
| DK (1) | DK2855527T3 (enExample) |
| ES (1) | ES2695151T3 (enExample) |
| MX (1) | MX361773B (enExample) |
| WO (1) | WO2013178736A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2451844B1 (en) | 2009-07-10 | 2015-04-22 | Innate Pharma | Tlr3 binding agents |
| CN104379603B (zh) | 2012-05-31 | 2017-11-07 | 先天制药公司 | Tlr3结合剂 |
| US20160136272A1 (en) * | 2013-05-14 | 2016-05-19 | Innate Pharma | Methods for restoring corticosteroid sensitivity |
| AR110755A1 (es) | 2017-01-20 | 2019-05-02 | Genzyme Corp | Anticuerpos dirigidos a hueso |
| TW202506185A (zh) | 2017-01-20 | 2025-02-16 | 法商賽諾菲公司 | 抗TGF-β抗體及其用途 |
| US10537585B2 (en) | 2017-12-18 | 2020-01-21 | Dexcel Pharma Technologies Ltd. | Compositions comprising dexamethasone |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US5567610A (en) | 1986-09-04 | 1996-10-22 | Bioinvent International Ab | Method of producing human monoclonal antibodies and kit therefor |
| US6673986B1 (en) | 1990-01-12 | 2004-01-06 | Abgenix, Inc. | Generation of xenogeneic antibodies |
| US5229275A (en) | 1990-04-26 | 1993-07-20 | Akzo N.V. | In-vitro method for producing antigen-specific human monoclonal antibodies |
| US5660827A (en) | 1992-03-05 | 1997-08-26 | Board Of Regents, The University Of Texas System | Antibodies that bind to endoglin |
| US5491084A (en) | 1993-09-10 | 1996-02-13 | The Trustees Of Columbia University In The City Of New York | Uses of green-fluorescent protein |
| US6267958B1 (en) | 1995-07-27 | 2001-07-31 | Genentech, Inc. | Protein formulation |
| AR006928A1 (es) | 1996-05-01 | 1999-09-29 | Pioneer Hi Bred Int | Una molecula de adn aislada que codifica una proteina fluorescente verde como marcador rastreable para la transformacion de plantas, un metodo para laproduccion de plantas transgenicas, un vector de expresion, una planta transgenica y celulas de dichas plantas. |
| CN101486759A (zh) | 1997-05-07 | 2009-07-22 | 先灵公司 | 人Toll样受体蛋白、相关试剂和方法 |
| DK0999853T3 (da) | 1997-06-13 | 2003-04-22 | Genentech Inc | Stabiliseret antostofformulering |
| JP4731793B2 (ja) | 2000-12-28 | 2011-07-27 | アルセア テクノロジーズ インコーポレイテッド | 抗体全体またはそのフラグメントの結晶、ならびにこの結晶を作製および使用するための方法 |
| US7595378B2 (en) | 2001-06-13 | 2009-09-29 | Genmab A/S | Human monoclonal antibodies to epidermal growth factor receptor (EGFR) |
| CA2467242A1 (en) | 2001-11-20 | 2003-05-30 | Seattle Genetics, Inc. | Treatment of immunological disorders using anti-cd30 antibodies |
| CA2480059C (en) | 2002-03-22 | 2015-11-24 | Amrad Operations Pty. Ltd. | Monoclonal antibody against interleukin-13 receptor alpha 1 (il-13r.alpha.1) |
| JP2004016021A (ja) | 2002-06-12 | 2004-01-22 | Japan Science & Technology Corp | 抗体および阻害剤並びにそれを用いた形質転換方法および形質転換キット |
| WO2004032828A2 (en) | 2002-07-31 | 2004-04-22 | Seattle Genetics, Inc. | Anti-cd20 antibody-drug conjugates for the treatment of cancer and immune disorders |
| AR051836A1 (es) * | 2004-11-30 | 2007-02-14 | Centocor Inc | Antagonistas de receptor 3 simil toll metodos y usos |
| JP5199878B2 (ja) | 2005-10-27 | 2013-05-15 | セントカー・インコーポレーテツド | Ｔｏｌｌ様受容体３モジュレーター、方法および用途 |
| DK1957539T3 (da) | 2005-12-08 | 2013-05-06 | Medarex Inc | Humane monoklonale antistoffer til proteintyrosinkinase 7 (ptk7) og deres anvendelse |
| US8354508B2 (en) | 2006-07-21 | 2013-01-15 | Diadexus, Inc. | PRO115 antibody compositions and methods of use |
| WO2008049897A1 (en) | 2006-10-27 | 2008-05-02 | Ablynx N.V. | Intranasal delivery of polypeptides and proteins |
| WO2008140826A1 (en) | 2007-05-15 | 2008-11-20 | Oncomed Pharmaceuticals, Inc. | Compositions and methods for diagnosing and treating cancer |
| CN102083984A (zh) * | 2007-12-26 | 2011-06-01 | 森托科尔奥索生物科技公司 | 食蟹猴Toll样受体3 |
| US20110076296A1 (en) | 2008-04-25 | 2011-03-31 | Innate Pharma S.A. | TLR3 Agonist Compositions |
| CA2742014A1 (en) | 2008-10-31 | 2010-05-06 | Centocor Ortho Biotech Inc. | Toll-like receptor 3 antagonists |
| US8460659B2 (en) | 2008-10-31 | 2013-06-11 | Janssen Biotech, Inc. | Toll-like receptor 3 antagonists for the treatment of metabolic and cardiovascular diseases |
| US20130090457A1 (en) | 2008-10-31 | 2013-04-11 | Janssen Biotech, Inc. | Toll-Like Receptor 3 Antagonists for the Treatment of Metabolic and Cardiovascular Diseases |
| CA2760525A1 (en) | 2009-04-29 | 2010-11-04 | Mark Cunningham | Toll-like receptor 3 antagonists |
| EP2451844B1 (en) | 2009-07-10 | 2015-04-22 | Innate Pharma | Tlr3 binding agents |
| EP2332986B1 (en) | 2009-12-11 | 2013-10-09 | Deutsches Krebsforschungszentrum | Antibody that binds to H-1 parvovirus |
| EP2663329A2 (en) | 2011-01-12 | 2013-11-20 | Innate Pharma | Tlr3 binding agents |
| CN104379603B (zh) | 2012-05-31 | 2017-11-07 | 先天制药公司 | Tlr3结合剂 |
-
2013
- 2013-05-30 CN CN201380028786.1A patent/CN104379603B/zh not_active Expired - Fee Related
- 2013-05-30 MX MX2014014443A patent/MX361773B/es active IP Right Grant
- 2013-05-30 EP EP13727110.2A patent/EP2855527B1/en not_active Not-in-force
- 2013-05-30 JP JP2015514499A patent/JP6356120B2/ja not_active Expired - Fee Related
- 2013-05-30 WO PCT/EP2013/061173 patent/WO2013178736A1/en not_active Ceased
- 2013-05-30 CA CA2874918A patent/CA2874918A1/en not_active Abandoned
- 2013-05-30 ES ES13727110T patent/ES2695151T3/es active Active
- 2013-05-30 DK DK13727110.2T patent/DK2855527T3/en active
- 2013-05-30 US US14/403,171 patent/US9944712B2/en active Active
- 2013-05-30 AU AU2013269652A patent/AU2013269652B2/en not_active Ceased