JP2015508063A5 - - Google Patents
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- Publication number
- JP2015508063A5 JP2015508063A5 JP2014554950A JP2014554950A JP2015508063A5 JP 2015508063 A5 JP2015508063 A5 JP 2015508063A5 JP 2014554950 A JP2014554950 A JP 2014554950A JP 2014554950 A JP2014554950 A JP 2014554950A JP 2015508063 A5 JP2015508063 A5 JP 2015508063A5
- Authority
- JP
- Japan
- Prior art keywords
- antigen
- binding fragment
- antibody
- seq
- asic1
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261592837P | 2012-01-31 | 2012-01-31 | |
| US61/592,837 | 2012-01-31 | ||
| US201261644038P | 2012-05-08 | 2012-05-08 | |
| US61/644,038 | 2012-05-08 | ||
| US201261692925P | 2012-08-24 | 2012-08-24 | |
| US61/692,925 | 2012-08-24 | ||
| PCT/US2013/023784 WO2013116296A1 (en) | 2012-01-31 | 2013-01-30 | Anti-asic1 antibodies and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015508063A JP2015508063A (ja) | 2015-03-16 |
| JP2015508063A5 true JP2015508063A5 (enExample) | 2016-03-10 |
| JP6302844B2 JP6302844B2 (ja) | 2018-03-28 |
Family
ID=47666522
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014554950A Active JP6302844B2 (ja) | 2012-01-31 | 2013-01-30 | 抗ａｓｉｃ１抗体及びその使用 |
Country Status (33)
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2809681T3 (en) | 2012-01-31 | 2019-03-11 | Regeneron Pharma | ANTI-ASIC1 antibodies and uses thereof |
| JP2017513854A (ja) | 2014-04-15 | 2017-06-01 | ソレント・セラピューティクス・インコーポレイテッドＳｏｒｒｅｎｔｏ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｉｎｃ． | Ｗｉｓｐ１に結合する抗原結合タンパク質 |
| KR20250099289A (ko) | 2014-05-16 | 2025-07-01 | 아블린쓰 엔.브이. | 개선된 면역글로불린 가변 도메인 |
| HUE050007T2 (hu) | 2014-05-16 | 2020-11-30 | Ablynx Nv | Immunglobulin variábilis domének |
| CN105233286B (zh) * | 2015-09-10 | 2018-10-30 | 上海交通大学医学院 | 含酸敏感离子通道调控剂的制剂及其在治疗瘙痒中的用途 |
| CN105713089B (zh) * | 2016-02-26 | 2019-08-06 | 上海科技大学 | 一种特异性抑制酸敏感离子通道i型的全人抗体 |
| WO2018085441A1 (en) * | 2016-11-01 | 2018-05-11 | Berg Llc | Filamin b binding proteins and uses thereof |
| EP3980456A4 (en) * | 2019-06-04 | 2023-01-18 | Shanghaitech University | AFFINITY MATURING ANTI-ASIC1A ANTIBODIES |
| BR112022000216A2 (pt) | 2019-07-11 | 2022-05-17 | Memorial Sloan Kettering Cancer Center | Anticorpos direcionados a dll3 e usos dos mesmos |
| WO2021012176A1 (en) * | 2019-07-23 | 2021-01-28 | Shanghaitech University | Asic1 channel antagonist antibody |
| CA3154387A1 (en) * | 2019-09-13 | 2021-03-18 | Tri-Institutional Therapeutics Discovery Institute, Inc. | Anti-cd371 antibodies and uses thereof |
| EP4384218A4 (en) * | 2021-08-09 | 2025-11-05 | Merck Patent Gmbh | Proteins that uncouple T-lymphocyte-mediated tumor cytotoxicity from the release of pro-inflammatory cytokines |
| JP2024534892A (ja) * | 2021-09-02 | 2024-09-26 | メモリアル スローン ケタリング キャンサー センター | 抗ｄｌｌ３抗体及びその使用 |
| CN119331085B (zh) * | 2024-10-16 | 2025-03-14 | 中国科学院合肥物质科学研究院 | 沙贝冠状病毒广谱中和抗体及其应用 |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2759373B1 (fr) | 1997-02-11 | 2001-05-04 | Centre Nat Rech Scient | Nouveau canal cationique neuronal de mammifere sensible a l'acidite, son clonage et ses applications |
| ES2279583T3 (es) | 1997-10-29 | 2007-08-16 | Mcgill University | Adn que codifica para un canal ionico regulado por protones humano y usos del mismo. |
| US6287859B1 (en) | 1998-08-05 | 2001-09-11 | Centre National De La Recherche | Identification, functional expression and chromosal localization of a sustained human proton-gated cation channel |
| CA2304494A1 (en) | 2000-04-20 | 2001-10-20 | Philippe Seguela | A novel heteromultimeric ion channel receptor and uses thereof |
| US6635432B1 (en) | 2000-04-25 | 2003-10-21 | University Of Iowa Research Foundation | Peptide potentiation of acid-sensory ion channel in pain |
| US7132505B1 (en) | 2001-05-10 | 2006-11-07 | Centre National De La Recherche Scientifique - Cnrs | Polypeptide inhibiting a proton-gated Na+ channel, a nucleic acid coding for such polypeptide and a method of manufacturing an ASIC1a channel blocker |
| CA2352702A1 (en) | 2001-07-18 | 2003-01-18 | Philippe Seguela | Novel human proton gated ion channel |
| AR039067A1 (es) | 2001-11-09 | 2005-02-09 | Pfizer Prod Inc | Anticuerpos para cd40 |
| CN1326879C (zh) * | 2002-03-29 | 2007-07-18 | 先灵公司 | 人源抗白细胞介素5单克隆抗体及其制备方法和包含这些抗体的组合物 |
| US20030186860A1 (en) | 2002-03-29 | 2003-10-02 | Welsh Michael J. | Novel compositions and methods for modulating the acid-sensing ion channel (ASIC) |
| US20070197583A1 (en) | 2002-03-29 | 2007-08-23 | Welsh Michael J | Novel compositions and methods for modulation of the acid-sensing ion channel (ASIC) for the treatment of anxiety and drug addiction |
| CA2538754A1 (en) | 2003-09-11 | 2005-03-24 | The Uab Research Foundation | Inhibition of inward sodium currents in cancer |
| WO2005074923A1 (en) | 2004-02-03 | 2005-08-18 | Agt Biosciences Limited | Methods and compositions |
| EP1734962A4 (en) | 2004-03-30 | 2010-07-14 | Painceptor Pharma Corp | COMPOSITIONS AND METHOD FOR MODULATING CONTROLLED ION CHANNELS |
| US7850962B2 (en) | 2004-04-20 | 2010-12-14 | Genmab A/S | Human monoclonal antibodies against CD20 |
| US7192500B2 (en) | 2004-04-30 | 2007-03-20 | Kimberly-Clark Worldwide, Inc. | Process for making a garment including an absorbent assembly |
| US8030442B2 (en) | 2004-09-16 | 2011-10-04 | Morehouse School Of Medicine | Treatment of injury to the brain by inhibition of acid sensing ion channels |
| WO2006068953A2 (en) * | 2004-12-21 | 2006-06-29 | Astrazeneca Ab | Antibodies directed to angiopoietin-2 and uses thereof |
| KR101203328B1 (ko) * | 2005-04-26 | 2012-11-20 | 화이자 인코포레이티드 | Ｐ-카드헤린 항체 |
| RS52176B (sr) | 2006-06-02 | 2012-08-31 | Regeneron Pharmaceuticals Inc. | Antitela visokog afiniteta prema humanom il-6 receptoru |
| EP2078732B1 (en) * | 2006-07-10 | 2015-09-16 | Fujita Health University | Method of identifying a candidate diagnostic or therapeutic antibody using flow cytometry |
| US8618113B2 (en) | 2006-07-14 | 2013-12-31 | Medical Research Council | Treatment for demyelinating disease |
| NO347649B1 (no) * | 2006-12-14 | 2024-02-12 | Regeneron Pharma | Humant antistoff eller antistoff fragment som spesifikt binder human deltaliknende ligand 4 (hDII4), nukleinsyremolekyl som koder for slike og vektor og vert-vektorsystemer, samt fremgangsmåte for fremstilling, sammensetning og anvendelse. |
| US7598039B2 (en) | 2007-01-30 | 2009-10-06 | Academia Sinica | Treatment of insulin resistance |
| DK2137539T3 (da) | 2007-04-03 | 2011-01-24 | Ilegusavnid Genetics Resource Ct Minestry Of Social Affairs And Health | Amolorid følsomme calciumkanaler forbundet med paniklidelser |
| CA2683145C (en) * | 2007-04-27 | 2018-06-12 | Katherine E. Lewis | Antagonists to il-17a, il-17f, and il-23p19 and methods of use |
| EP2288922B1 (en) * | 2008-05-08 | 2016-08-17 | University of Utah Research Foundation | Sensory receptors for chronic fatigue and pain and uses thereof |
| US20090291150A1 (en) | 2008-05-21 | 2009-11-26 | University Of Iowa Research Foundation | Method and compositions for treating and preventing seizures by modulating acid-sensing ion channel activity |
| FR2932091B1 (fr) | 2008-06-06 | 2012-12-28 | Centre Nat Rech Scient | Effets analgesiques de la toxine peptidique apetx2 |
| DK2356270T3 (da) * | 2008-11-07 | 2016-12-12 | Fabrus Llc | Kombinatoriske antistofbiblioteker og anvendelser deraf |
| JO3672B1 (ar) * | 2008-12-15 | 2020-08-27 | Regeneron Pharma | أجسام مضادة بشرية عالية التفاعل الكيماوي بالنسبة لإنزيم سبتيليسين كنفرتيز بروبروتين / كيكسين نوع 9 (pcsk9). |
| US8926976B2 (en) * | 2009-09-25 | 2015-01-06 | Xoma Technology Ltd. | Modulators |
| GB0922434D0 (en) * | 2009-12-22 | 2010-02-03 | Ucb Pharma Sa | antibodies and fragments thereof |
| CN102234316B (zh) * | 2010-05-07 | 2014-01-29 | 中国人民解放军军事医学科学院毒物药物研究所 | 具有增强酸感受离子通道1a电流作用的多肽及其用途 |
| US9371383B2 (en) | 2012-01-31 | 2016-06-21 | Regeneron Pharmaceuticals, Inc. | Anti-ASIC1 antibodies and uses thereof |
| DK2809681T3 (en) | 2012-01-31 | 2019-03-11 | Regeneron Pharma | ANTI-ASIC1 antibodies and uses thereof |
-
2013
- 2013-01-30 DK DK13702876.7T patent/DK2809681T3/en active
- 2013-01-30 PL PL18201823T patent/PL3453723T3/pl unknown
- 2013-01-30 AR ARP130100280 patent/AR089852A1/es active IP Right Grant
- 2013-01-30 SI SI201331343T patent/SI2809681T1/sl unknown
- 2013-01-30 NZ NZ626242A patent/NZ626242A/en unknown
- 2013-01-30 CN CN201380007553.3A patent/CN104093738B/zh active Active
- 2013-01-30 EP EP18201823.4A patent/EP3453723B1/en active Active
- 2013-01-30 US US13/753,836 patent/US9150648B2/en active Active
- 2013-01-30 ES ES13702876T patent/ES2707599T3/es active Active
- 2013-01-30 RS RS20211284A patent/RS62454B1/sr unknown
- 2013-01-30 JP JP2014554950A patent/JP6302844B2/ja active Active
- 2013-01-30 LT LTEP13702876.7T patent/LT2809681T/lt unknown
- 2013-01-30 CA CA2862332A patent/CA2862332C/en active Active
- 2013-01-30 EA EA201491452A patent/EA028647B1/ru not_active IP Right Cessation
- 2013-01-30 LT LTEP18201823.4T patent/LT3453723T/lt unknown
- 2013-01-30 SG SG11201403222UA patent/SG11201403222UA/en unknown
- 2013-01-30 ES ES18201823T patent/ES2886123T3/es active Active
- 2013-01-30 EP EP13702876.7A patent/EP2809681B1/en active Active
- 2013-01-30 SI SI201331923T patent/SI3453723T1/sl unknown
- 2013-01-30 MX MX2014008541A patent/MX358518B/es active IP Right Grant
- 2013-01-30 KR KR1020147020682A patent/KR102111941B1/ko active Active
- 2013-01-30 PL PL13702876T patent/PL2809681T3/pl unknown
- 2013-01-30 IN IN4645CHN2014 patent/IN2014CN04645A/en unknown
- 2013-01-30 SM SM20210628T patent/SMT202100628T1/it unknown
- 2013-01-30 HU HUE18201823A patent/HUE056335T2/hu unknown
- 2013-01-30 HU HUE13702876A patent/HUE042531T2/hu unknown
- 2013-01-30 PT PT182018234T patent/PT3453723T/pt unknown
- 2013-01-30 AU AU2013215254A patent/AU2013215254B2/en active Active
- 2013-01-30 DK DK18201823.4T patent/DK3453723T3/da active
- 2013-01-30 HR HRP20190358TT patent/HRP20190358T1/hr unknown
- 2013-01-30 WO PCT/US2013/023784 patent/WO2013116296A1/en not_active Ceased
- 2013-01-30 JO JOP/2013/0036A patent/JO3547B1/ar active
- 2013-01-30 RS RS20190287A patent/RS58439B1/sr unknown
- 2013-01-30 PT PT13702876T patent/PT2809681T/pt unknown
- 2013-01-30 HR HRP20211541TT patent/HRP20211541T1/hr unknown
- 2013-01-30 MY MYPI2014001721A patent/MY168748A/en unknown
- 2013-01-30 TW TW102103458A patent/TWI591073B/zh active
- 2013-01-31 UY UY34603A patent/UY34603A/es not_active Application Discontinuation
-
2014
- 2014-06-26 IL IL233410A patent/IL233410A0/en unknown
- 2014-07-11 PH PH12014501613A patent/PH12014501613A1/en unknown
- 2014-07-25 CO CO14162499A patent/CO7020877A2/es unknown
- 2014-07-30 CL CL2014002019A patent/CL2014002019A1/es unknown
-
2015
- 2015-09-09 US US14/848,452 patent/US20160002332A1/en not_active Abandoned
-
2017
- 2017-09-11 IL IL254416A patent/IL254416B/en active IP Right Grant
- 2017-09-28 US US15/719,220 patent/US10513557B2/en active Active
-
2019
- 2019-02-27 CY CY20191100246T patent/CY1121368T1/el unknown
-
2021
- 2021-11-09 CY CY20211100968T patent/CY1124778T1/el unknown
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