JP2015516450A5 - - Google Patents
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- Publication number
- JP2015516450A5 JP2015516450A5 JP2015511956A JP2015511956A JP2015516450A5 JP 2015516450 A5 JP2015516450 A5 JP 2015516450A5 JP 2015511956 A JP2015511956 A JP 2015511956A JP 2015511956 A JP2015511956 A JP 2015511956A JP 2015516450 A5 JP2015516450 A5 JP 2015516450A5
- Authority
- JP
- Japan
- Prior art keywords
- pain
- weeks
- refers
- treated
- therapeutically effective
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12003896 | 2012-05-18 | ||
| EP12003896.3 | 2012-05-18 | ||
| PCT/EP2013/001469 WO2013170970A1 (en) | 2012-05-18 | 2013-05-16 | Pharmaceutical composition comprising (1r,4r)-6'-fluoro-n,n-dimethyl-4-phenyl-4',9'-dihydro-3'h-spiro[cyclohexane-1,1'-pyrano [3,4,b]indol]-4-amine and an oxicam |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015516450A JP2015516450A (ja) | 2015-06-11 |
| JP2015516450A5 true JP2015516450A5 (enExample) | 2017-03-09 |
| JP6116677B2 JP6116677B2 (ja) | 2017-04-19 |
Family
ID=48470899
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015511956A Active JP6116677B2 (ja) | 2012-05-18 | 2013-05-16 | (1r,4r)−6’−フルオロ−N,N−ジメチル−4−フェニル−4’,9’−ジヒドロ−3’H−スピロ[シクロヘキサン−1,1’−ピラノ[3,4,b]インドール]−4−アミンおよびオキシカムを含む医薬組成物 |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US9308196B2 (enExample) |
| EP (1) | EP2849746B1 (enExample) |
| JP (1) | JP6116677B2 (enExample) |
| CN (2) | CN108451956A (enExample) |
| AU (1) | AU2013262076B2 (enExample) |
| BR (1) | BR112014028569A2 (enExample) |
| CA (1) | CA2873863A1 (enExample) |
| CY (1) | CY1119824T1 (enExample) |
| DK (1) | DK2849746T3 (enExample) |
| EA (1) | EA026719B1 (enExample) |
| ES (1) | ES2659948T3 (enExample) |
| HR (1) | HRP20171843T1 (enExample) |
| HU (1) | HUE035122T2 (enExample) |
| IL (1) | IL235652B (enExample) |
| LT (1) | LT2849746T (enExample) |
| MX (1) | MX354685B (enExample) |
| NO (1) | NO2849746T3 (enExample) |
| PL (1) | PL2849746T3 (enExample) |
| PT (1) | PT2849746T (enExample) |
| RS (1) | RS56830B1 (enExample) |
| SI (1) | SI2849746T1 (enExample) |
| WO (1) | WO2013170970A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA201791662A1 (ru) | 2015-01-23 | 2017-12-29 | Грюненталь Гмбх | Цебранопадол для лечения от боли субъектов с нарушенной печеночной и/или нарушенной почечной функцией |
| JP7373904B2 (ja) | 2016-02-29 | 2023-11-06 | パーク・セラピューティクス・インコーポレイテッド | セブラノパドールの滴定 |
| GB202405898D0 (en) * | 2024-04-26 | 2024-06-12 | Univ Surrey | Mycobacterial infections |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3273329D1 (en) | 1981-06-26 | 1986-10-23 | Upjohn Co | Analgesic process and composition |
| US4389393A (en) | 1982-03-26 | 1983-06-21 | Forest Laboratories, Inc. | Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose |
| US4783337A (en) | 1983-05-11 | 1988-11-08 | Alza Corporation | Osmotic system comprising plurality of members for dispensing drug |
| US4612008A (en) | 1983-05-11 | 1986-09-16 | Alza Corporation | Osmotic device with dual thermodynamic activity |
| US4765989A (en) | 1983-05-11 | 1988-08-23 | Alza Corporation | Osmotic device for administering certain drugs |
| DK0473655T3 (da) | 1989-05-22 | 1997-02-10 | Biochemical Veterinary Res | Divalente metalsalte af indomethacin |
| US5472711A (en) | 1992-07-30 | 1995-12-05 | Edward Mendell Co., Inc. | Agglomerated hydrophilic complexes with multi-phasic release characteristics |
| US5330761A (en) | 1993-01-29 | 1994-07-19 | Edward Mendell Co. Inc. | Bioadhesive tablet for non-systemic use products |
| US5455046A (en) | 1993-09-09 | 1995-10-03 | Edward Mendell Co., Inc. | Sustained release heterodisperse hydrogel systems for insoluble drugs |
| US5399362A (en) | 1994-04-25 | 1995-03-21 | Edward Mendell Co., Inc. | Once-a-day metoprolol oral dosage form |
| US5914129A (en) | 1996-07-23 | 1999-06-22 | Mauskop; Alexander | Analgesic composition for treatment of migraine headaches |
| RS49982B (sr) * | 1997-09-17 | 2008-09-29 | Euro-Celtique S.A., | Sinergistička analgetička kombinacija analgetičkog opijata i inhibitora ciklooksigenaze-2 |
| JP5026635B2 (ja) * | 1998-09-10 | 2012-09-12 | ニュコメデ ダンマルク アンパーツセルスカブ | 医薬物質の迅速放出医薬組成物 |
| ATE279920T1 (de) | 2000-12-28 | 2004-11-15 | Fresenius Kabi Austria Gmbh | Stabile infusionslösung von diclofenac-salzen, deren herstellung und verwendung |
| PT1374906E (pt) | 2002-06-17 | 2007-07-24 | Chiesi Farma Spa | Um processo para a preparação de compostos de inclusão de piroxicam: beta-ciclodextrina |
| AR040778A1 (es) * | 2002-08-06 | 2005-04-20 | Glaxo Group Ltd | Anticuerpos alterados o fragmentos funcionales que se unen a mag (glicoproteina asociada a mielina). |
| DE10252667A1 (de) | 2002-11-11 | 2004-05-27 | Grünenthal GmbH | Spirocyclische Cyclohexan-Derivate |
| DE10257824B4 (de) | 2002-12-10 | 2004-11-11 | Kochem, Hans-Günter, Dr. | Zusammensetzung zur Schmerzbehandlung, insbesondere zur Behandlung von Gelenkschmerzen |
| US20100297252A1 (en) | 2003-03-03 | 2010-11-25 | Elan Pharma International Ltd. | Nanoparticulate meloxicam formulations |
| US7132452B2 (en) | 2003-03-10 | 2006-11-07 | Fang-Yu Lee | Topical formulation having effects on alleviating pain/inflammation caused by herpes virus infection |
| DE10360792A1 (de) | 2003-12-23 | 2005-07-28 | Grünenthal GmbH | Spirocyclische Cyclohexan-Derivate |
| EP1893610A2 (en) | 2005-06-17 | 2008-03-05 | Pfizer, Inc. | Alpha-(aryl-or heteroaryl-methyl)-beta piperidino propanamide compounds as orl1-receptor antagonists |
| CN102671195B (zh) * | 2006-04-28 | 2016-01-20 | 格吕伦塔尔有限公司 | 包含3-(3-二甲基氨基-1-乙基-2-甲基-丙基)-苯酚和nsaid的药物组合物 |
| CN101147735A (zh) | 2006-09-19 | 2008-03-26 | 沈阳华泰药物研究有限公司 | 注射用药物组合物及其药盒 |
| DE102006046745A1 (de) * | 2006-09-29 | 2008-04-03 | Grünenthal GmbH | Gemischte ORL1/µ-Agonisten zur Behandlung von Schmerz |
| DE102006056458A1 (de) | 2006-11-28 | 2008-05-29 | Grünenthal GmbH | Arzneimittelzubereitung von Tramadol und Acetaminophen |
| CN100560061C (zh) | 2008-06-20 | 2009-11-18 | 海南锦瑞制药股份有限公司 | 一种氯诺昔康冻干粉针剂及其制备方法 |
| AU2009289736A1 (en) * | 2008-09-05 | 2010-03-11 | Grunenthal Gmbh | Pharmaceutical combination comprising 6-Dimethylaminomethyl-1-(3-methoxy-phenyl)-cyclohexane-1,3-diol and an NSAID |
| WO2010025931A2 (en) * | 2008-09-05 | 2010-03-11 | Grünenthal GmbH | Pharmaceutical combination |
| SI2600846T1 (sl) * | 2010-08-04 | 2016-02-29 | Gruenenthal Gmbh | Farmacevtska odmerna oblika, ki obsega 6'-fluoro-(N-metil- ali N,N-dimetil-)-4-fenil-4',9'-dihidro-3'H-spiro(cikloheksan-1,1'-pirano (3,4,b)indol)-4-amin |
| DK2600851T3 (en) * | 2010-08-04 | 2018-06-25 | Gruenenthal Gmbh | PHARMACEUTICAL DOSAGE FORM CONTAINING 6'-FLUORO- (N-METHYL OR N, N-DIMETHYL -) - 4-PHENYL-4 ', 9'-DIHYDRO-3'H-SPIRO [CYCLOHEXAN-1,1'-PYRANO [3,4, B] INDOL] -4-AMINE FOR TREATMENT OF NEUROPATHIC PAIN |
| BR112013004055A2 (pt) * | 2010-08-04 | 2018-04-24 | Gruenenthal Gmbh | Forma de dosagem farmacêutica compreendendo 6'-fluor-(n-metil- ou n, n-dimetil-)-4-fenil-4',9'-di- hidro-3'h-espiro[cicloexano-1,1'-pirano[3,4-b]indol]-4 -amina. |
-
2013
- 2013-05-13 US US13/892,362 patent/US9308196B2/en active Active
- 2013-05-16 ES ES13724168.3T patent/ES2659948T3/es active Active
- 2013-05-16 PL PL13724168T patent/PL2849746T3/pl unknown
- 2013-05-16 MX MX2014012862A patent/MX354685B/es active IP Right Grant
- 2013-05-16 EA EA201401265A patent/EA026719B1/ru not_active IP Right Cessation
- 2013-05-16 DK DK13724168.3T patent/DK2849746T3/en active
- 2013-05-16 CA CA2873863A patent/CA2873863A1/en not_active Abandoned
- 2013-05-16 AU AU2013262076A patent/AU2013262076B2/en not_active Ceased
- 2013-05-16 HU HUE13724168A patent/HUE035122T2/en unknown
- 2013-05-16 BR BR112014028569A patent/BR112014028569A2/pt not_active IP Right Cessation
- 2013-05-16 CN CN201810667716.5A patent/CN108451956A/zh active Pending
- 2013-05-16 WO PCT/EP2013/001469 patent/WO2013170970A1/en not_active Ceased
- 2013-05-16 LT LTEP13724168.3T patent/LT2849746T/lt unknown
- 2013-05-16 HR HRP20171843TT patent/HRP20171843T1/hr unknown
- 2013-05-16 EP EP13724168.3A patent/EP2849746B1/en not_active Not-in-force
- 2013-05-16 RS RS20180128A patent/RS56830B1/sr unknown
- 2013-05-16 CN CN201380025679.3A patent/CN104302288A/zh active Pending
- 2013-05-16 PT PT137241683T patent/PT2849746T/pt unknown
- 2013-05-16 NO NO13724168A patent/NO2849746T3/no unknown
- 2013-05-16 SI SI201330919T patent/SI2849746T1/en unknown
- 2013-05-16 JP JP2015511956A patent/JP6116677B2/ja active Active
-
2014
- 2014-11-12 IL IL235652A patent/IL235652B/en active IP Right Grant
-
2018
- 2018-01-24 CY CY20181100090T patent/CY1119824T1/el unknown
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