JP2015516452A5 - - Google Patents

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Publication number
JP2015516452A5
JP2015516452A5 JP2015511958A JP2015511958A JP2015516452A5 JP 2015516452 A5 JP2015516452 A5 JP 2015516452A5 JP 2015511958 A JP2015511958 A JP 2015511958A JP 2015511958 A JP2015511958 A JP 2015511958A JP 2015516452 A5 JP2015516452 A5 JP 2015516452A5
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JP
Japan
Prior art keywords
pain
weeks
refers
treated
therapeutically effective
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
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JP2015511958A
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English (en)
Japanese (ja)
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JP2015516452A (ja
JP6116679B2 (ja
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Application filed filed Critical
Priority claimed from PCT/EP2013/001471 external-priority patent/WO2013170972A1/en
Publication of JP2015516452A publication Critical patent/JP2015516452A/ja
Publication of JP2015516452A5 publication Critical patent/JP2015516452A5/ja
Application granted granted Critical
Publication of JP6116679B2 publication Critical patent/JP6116679B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2015511958A 2012-05-18 2013-05-16 (1r,4r)−6’−フルオロ−N,N−ジメチル−4−フェニル−4’,9’−ジヒドロ−3’H−スピロ[シクロヘキサン−1,1’−ピラノ[3,4,b]インドール]−4−アミンおよび抗けいれん剤を含む医薬組成物 Active JP6116679B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP12003898 2012-05-18
EP12003898.9 2012-05-18
EP13159330 2013-03-15
EP13159330.3 2013-03-15
PCT/EP2013/001471 WO2013170972A1 (en) 2012-05-18 2013-05-16 Pharmaceutical composition comprising (1r,4r)-6'-fluoro-n,n-dimethyl-4-phenyl-4',9'-dihydro-3'h-spiro[cyclohexane-1,1'-pyrano [3,4,b]indol]-4-amine and an anticonvulsant

Publications (3)

Publication Number Publication Date
JP2015516452A JP2015516452A (ja) 2015-06-11
JP2015516452A5 true JP2015516452A5 (enExample) 2017-03-09
JP6116679B2 JP6116679B2 (ja) 2017-04-19

Family

ID=48446244

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015511958A Active JP6116679B2 (ja) 2012-05-18 2013-05-16 (1r,4r)−6’−フルオロ−N,N−ジメチル−4−フェニル−4’,9’−ジヒドロ−3’H−スピロ[シクロヘキサン−1,1’−ピラノ[3,4,b]インドール]−4−アミンおよび抗けいれん剤を含む医薬組成物

Country Status (20)

Country Link
US (1) US9345689B2 (enExample)
EP (1) EP2852384B1 (enExample)
JP (1) JP6116679B2 (enExample)
CN (1) CN104284656A (enExample)
AU (1) AU2013262078B2 (enExample)
CA (1) CA2873871A1 (enExample)
CY (1) CY1118634T1 (enExample)
DK (1) DK2852384T3 (enExample)
EA (1) EA029767B1 (enExample)
ES (1) ES2624220T3 (enExample)
HR (1) HRP20170517T1 (enExample)
HU (1) HUE031984T2 (enExample)
IL (1) IL235654A (enExample)
LT (1) LT2852384T (enExample)
MX (1) MX353177B (enExample)
PL (1) PL2852384T3 (enExample)
PT (1) PT2852384T (enExample)
RS (1) RS55905B1 (enExample)
SI (1) SI2852384T1 (enExample)
WO (1) WO2013170972A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10022353B2 (en) 2015-01-23 2018-07-17 Grünenthal GmbH Cebranopadol for treating pain in subjects with impaired hepatic and/or impaired renal function
EP3419621A4 (en) * 2016-02-26 2019-10-30 The Johns Hopkins University PHARMACOLOGICAL MODULATORS OF NAV1.1 VOLTAGE-CONTROLLED SODIUM CHANNELS ASSOCIATED WITH MECHANICAL PAIN
WO2017195144A1 (en) * 2016-05-12 2017-11-16 Jubilant Generics Limited Pharmaceutical compositions comprising brivaracetam
JP7264813B2 (ja) * 2016-12-06 2023-04-25 トピカル・イノベーションズ・ベー・フェー 末梢神経障害性疼痛の治療に使用するための局所作用用フェニトイン
EP3826610A4 (en) * 2018-07-24 2022-05-04 Zenvision Pharma LLP Nasal drug delivery system of brivaracetam or salt thereof

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US5399362A (en) 1994-04-25 1995-03-21 Edward Mendell Co., Inc. Once-a-day metoprolol oral dosage form
US20030056896A1 (en) * 1995-05-12 2003-03-27 Frank Jao Effective therapy for epilepsies
US6117900A (en) 1999-09-27 2000-09-12 Asta Medica Aktiengesellschaft Use of retigabine for the treatment of neuropathic pain
US8637512B2 (en) 2002-07-29 2014-01-28 Glaxo Group Limited Formulations and method of treatment
DE10252667A1 (de) * 2002-11-11 2004-05-27 Grünenthal GmbH Spirocyclische Cyclohexan-Derivate
US8288372B2 (en) 2002-11-26 2012-10-16 Alexza Pharmaceuticals, Inc. Method for treating headache with loxapine
US20040222123A1 (en) * 2003-05-06 2004-11-11 Barr Laboratories, Inc. Kit for pharmaceuticals
CN1245379C (zh) 2003-10-30 2006-03-15 曹桂东 加巴喷丁的制法
DE10360792A1 (de) 2003-12-23 2005-07-28 Grünenthal GmbH Spirocyclische Cyclohexan-Derivate
GB0412878D0 (en) 2004-06-09 2004-07-14 Pfizer Ltd Use
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US8093408B2 (en) 2005-06-21 2012-01-10 The Company Wockhardt Antidepressant oral pharmaceutical compositions
US20080014271A1 (en) 2006-07-13 2008-01-17 Ucb, S.A. Novel pharmaceutical compositions comprising levetiracetam
DE102006046745A1 (de) 2006-09-29 2008-04-03 Grünenthal GmbH Gemischte ORL1/µ-Agonisten zur Behandlung von Schmerz
JP2008106028A (ja) * 2006-10-26 2008-05-08 Boehringer Ingelheim Internatl Gmbh 慢性疼痛の治療におけるフリバンセリンの使用
US20080153874A1 (en) 2006-12-22 2008-06-26 Allergan Inc. Alpha-2b receptor agonist and anticonvulsant compositions for treating chronic pain
WO2008108639A1 (en) 2007-03-08 2008-09-12 Avantium Holding B.V. Co-crystalline forms of carbamazepine
EP1977744A1 (en) 2007-04-03 2008-10-08 Chemo Ibérica, S.A. Polymorphic Form alpha of (S)-Pregabalin and process for its preparation
CA2710318A1 (en) * 2007-12-21 2009-07-09 Paz Arzneimittel-Entwicklungsgesellscaft Mbh Drugs as well as their production and use in the treatment of pain-associated neuropathies
US20090298947A1 (en) 2008-05-28 2009-12-03 Pliva Hrvatska D.O.O. Polymorphic and amorphous forms of lacosamide and amorphous compositions
SI2331210T1 (sl) * 2008-09-05 2014-10-30 Gruenenthal Gmbh Farmacevtska kombinacija 3-(3-dimetilamino-1-etil-2-metil-propil)-fenola in antiepileptika
DE102009013613A1 (de) 2009-03-17 2010-09-23 Ratiopharm Gmbh Trockenverarbeitung von Retigabin
EP2600850B1 (en) * 2010-08-04 2018-10-17 Grünenthal GmbH Pharmaceutical dosage form comprising 6'-fluoro-(n-methyl- or n,n-dimethyl-)-4-phenyl-4',9'-dihydro-3'h-spiro[cyclohexane-1,1'-pyrano[3,4,b]indol]-4-amine for the treatment of nociceptive pain
PL2600838T3 (pl) * 2010-08-04 2016-02-29 Gruenenthal Gmbh Farmaceutyczna postać dawkowania zawierająca 6'-fluoro-(N-metylo- lub N,N-dimetylo)-4-fenylo-4'9'-dihydro-3'H-spiro[cykloheksano-1,1'-pirano[3,4b]indolo]-4-aminę
JP6010534B2 (ja) * 2010-08-04 2016-10-19 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 6’−フルオロ−(N−メチル−又はN,N−ジメチル−)−4−フェニル−4’,9’−ジヒドロ−3’H−スピロ[シクロヘキサン−1,1’−ピラノ[3,4,b]インドール]−4−アミンを含む医薬剤形

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