EA029767B1 - ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, СОДЕРЖАЩАЯ (1r,4r)-6'-ФТОР-N,N-ДИМЕТИЛ-4-ФЕНИЛ-4',9'-ДИГИДРО -3'H-СПИРО[ЦИКЛОГЕКСАН-1,1'-ПИРАНО[3,4,b]ИНДОЛ]-4-АМИН И АНТИКОНВУЛЬСАНТ - Google Patents
ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, СОДЕРЖАЩАЯ (1r,4r)-6'-ФТОР-N,N-ДИМЕТИЛ-4-ФЕНИЛ-4',9'-ДИГИДРО -3'H-СПИРО[ЦИКЛОГЕКСАН-1,1'-ПИРАНО[3,4,b]ИНДОЛ]-4-АМИН И АНТИКОНВУЛЬСАНТ Download PDFInfo
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- EA029767B1 EA029767B1 EA201401271A EA201401271A EA029767B1 EA 029767 B1 EA029767 B1 EA 029767B1 EA 201401271 A EA201401271 A EA 201401271A EA 201401271 A EA201401271 A EA 201401271A EA 029767 B1 EA029767 B1 EA 029767B1
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- EA
- Eurasian Patent Office
- Prior art keywords
- pharmacologically active
- active ingredient
- pharmaceutical dosage
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- dosage form
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- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
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- A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
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Landscapes
- Health & Medical Sciences (AREA)
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- Life Sciences & Earth Sciences (AREA)
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- Medicinal Chemistry (AREA)
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- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Emergency Medicine (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12003898 | 2012-05-18 | ||
| EP13159330 | 2013-03-15 | ||
| PCT/EP2013/001471 WO2013170972A1 (en) | 2012-05-18 | 2013-05-16 | Pharmaceutical composition comprising (1r,4r)-6'-fluoro-n,n-dimethyl-4-phenyl-4',9'-dihydro-3'h-spiro[cyclohexane-1,1'-pyrano [3,4,b]indol]-4-amine and an anticonvulsant |
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| EA201401271A1 EA201401271A1 (ru) | 2015-05-29 |
| EA029767B1 true EA029767B1 (ru) | 2018-05-31 |
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| EA201401271A EA029767B1 (ru) | 2012-05-18 | 2013-05-16 | ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, СОДЕРЖАЩАЯ (1r,4r)-6'-ФТОР-N,N-ДИМЕТИЛ-4-ФЕНИЛ-4',9'-ДИГИДРО -3'H-СПИРО[ЦИКЛОГЕКСАН-1,1'-ПИРАНО[3,4,b]ИНДОЛ]-4-АМИН И АНТИКОНВУЛЬСАНТ |
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| EP (1) | EP2852384B1 (enExample) |
| JP (1) | JP6116679B2 (enExample) |
| CN (1) | CN104284656A (enExample) |
| AU (1) | AU2013262078B2 (enExample) |
| CA (1) | CA2873871A1 (enExample) |
| CY (1) | CY1118634T1 (enExample) |
| DK (1) | DK2852384T3 (enExample) |
| EA (1) | EA029767B1 (enExample) |
| ES (1) | ES2624220T3 (enExample) |
| HR (1) | HRP20170517T1 (enExample) |
| HU (1) | HUE031984T2 (enExample) |
| IL (1) | IL235654A (enExample) |
| LT (1) | LT2852384T (enExample) |
| MX (1) | MX353177B (enExample) |
| PL (1) | PL2852384T3 (enExample) |
| PT (1) | PT2852384T (enExample) |
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| SI (1) | SI2852384T1 (enExample) |
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|---|---|---|---|---|
| CA2974578C (en) | 2015-01-23 | 2020-11-17 | Grunenthal Gmbh | Cebranopadol for treating pain in subjects with impaired hepatic and/or impaired renal function |
| US20190060284A1 (en) * | 2016-02-26 | 2019-02-28 | The Johns Hopkins University | Pharmacological modulators of nav1.1 voltage-gated sodium channels associated with mechanical pain |
| US20190125725A1 (en) * | 2016-05-12 | 2019-05-02 | Jubilant Generics Limited | Pharmaceutical compositions comprising brivaracetam |
| JP7264813B2 (ja) * | 2016-12-06 | 2023-04-25 | トピカル・イノベーションズ・ベー・フェー | 末梢神経障害性疼痛の治療に使用するための局所作用用フェニトイン |
| EP3826610A4 (en) * | 2018-07-24 | 2022-05-04 | Zenvision Pharma LLP | Nasal drug delivery system of brivaracetam or salt thereof |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6117900A (en) * | 1999-09-27 | 2000-09-12 | Asta Medica Aktiengesellschaft | Use of retigabine for the treatment of neuropathic pain |
| US20040192690A1 (en) * | 2002-07-29 | 2004-09-30 | Buxton Ian Richard | Novel formulations and method of treatment |
| WO2005066183A1 (de) * | 2003-12-23 | 2005-07-21 | Grünenthal GmbH | Spirocyclische cyclohexan-derivate mit affinität zum orl1-rezeptor |
| US20080125475A1 (en) * | 2006-09-29 | 2008-05-29 | Grunenthal Gmbh | Mixed ORL1/mu-agonists for the treatment of pain |
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- 2013-05-13 US US13/892,751 patent/US9345689B2/en not_active Expired - Fee Related
- 2013-05-16 RS RS20170381A patent/RS55905B1/sr unknown
- 2013-05-16 HU HUE13723004A patent/HUE031984T2/en unknown
- 2013-05-16 EP EP13723004.1A patent/EP2852384B1/en not_active Not-in-force
- 2013-05-16 CN CN201380025637.XA patent/CN104284656A/zh active Pending
- 2013-05-16 EA EA201401271A patent/EA029767B1/ru not_active IP Right Cessation
- 2013-05-16 PT PT137230041T patent/PT2852384T/pt unknown
- 2013-05-16 MX MX2014013179A patent/MX353177B/es active IP Right Grant
- 2013-05-16 PL PL13723004T patent/PL2852384T3/pl unknown
- 2013-05-16 AU AU2013262078A patent/AU2013262078B2/en not_active Ceased
- 2013-05-16 HR HRP20170517TT patent/HRP20170517T1/hr unknown
- 2013-05-16 CA CA2873871A patent/CA2873871A1/en not_active Abandoned
- 2013-05-16 JP JP2015511958A patent/JP6116679B2/ja active Active
- 2013-05-16 SI SI201330569A patent/SI2852384T1/sl unknown
- 2013-05-16 LT LTEP13723004.1T patent/LT2852384T/lt unknown
- 2013-05-16 ES ES13723004.1T patent/ES2624220T3/es active Active
- 2013-05-16 DK DK13723004.1T patent/DK2852384T3/en active
- 2013-05-16 WO PCT/EP2013/001471 patent/WO2013170972A1/en not_active Ceased
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- 2017-02-15 CY CY20171100205T patent/CY1118634T1/el unknown
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Also Published As
| Publication number | Publication date |
|---|---|
| SI2852384T1 (sl) | 2017-04-26 |
| WO2013170972A1 (en) | 2013-11-21 |
| US9345689B2 (en) | 2016-05-24 |
| CY1118634T1 (el) | 2017-07-12 |
| EP2852384A1 (en) | 2015-04-01 |
| HUE031984T2 (en) | 2017-08-28 |
| MX2014013179A (es) | 2015-01-19 |
| IL235654A (en) | 2017-07-31 |
| CA2873871A1 (en) | 2013-11-21 |
| IL235654A0 (en) | 2015-01-29 |
| LT2852384T (lt) | 2017-04-25 |
| AU2013262078B2 (en) | 2017-10-26 |
| DK2852384T3 (en) | 2017-05-08 |
| PT2852384T (pt) | 2017-05-10 |
| PL2852384T3 (pl) | 2017-09-29 |
| US20130317009A1 (en) | 2013-11-28 |
| RS55905B1 (sr) | 2017-09-29 |
| JP2015516452A (ja) | 2015-06-11 |
| JP6116679B2 (ja) | 2017-04-19 |
| EA201401271A1 (ru) | 2015-05-29 |
| HRP20170517T1 (hr) | 2017-06-02 |
| AU2013262078A1 (en) | 2015-01-22 |
| CN104284656A (zh) | 2015-01-14 |
| ES2624220T3 (es) | 2017-07-13 |
| HK1204937A1 (en) | 2015-12-11 |
| MX353177B (es) | 2018-01-05 |
| EP2852384B1 (en) | 2017-02-01 |
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