EA026719B1 - Фармацевтическая композиция, содержащая (1r,4r)-6'-фтор-n,n-диметил-4-фенил-4',9'-дигидро-3'h-спиро[циклогексан-1,1'-пирано-[3,4,b]индол]-4-амин и мелоксикам - Google Patents
Фармацевтическая композиция, содержащая (1r,4r)-6'-фтор-n,n-диметил-4-фенил-4',9'-дигидро-3'h-спиро[циклогексан-1,1'-пирано-[3,4,b]индол]-4-амин и мелоксикам Download PDFInfo
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- EA026719B1 EA026719B1 EA201401265A EA201401265A EA026719B1 EA 026719 B1 EA026719 B1 EA 026719B1 EA 201401265 A EA201401265 A EA 201401265A EA 201401265 A EA201401265 A EA 201401265A EA 026719 B1 EA026719 B1 EA 026719B1
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- EA
- Eurasian Patent Office
- Prior art keywords
- pharmacologically active
- active ingredient
- accordance
- pharmaceutical dosage
- dosage form
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12003896 | 2012-05-18 | ||
| PCT/EP2013/001469 WO2013170970A1 (en) | 2012-05-18 | 2013-05-16 | Pharmaceutical composition comprising (1r,4r)-6'-fluoro-n,n-dimethyl-4-phenyl-4',9'-dihydro-3'h-spiro[cyclohexane-1,1'-pyrano [3,4,b]indol]-4-amine and an oxicam |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA201401265A1 EA201401265A1 (ru) | 2015-05-29 |
| EA026719B1 true EA026719B1 (ru) | 2017-05-31 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201401265A EA026719B1 (ru) | 2012-05-18 | 2013-05-16 | Фармацевтическая композиция, содержащая (1r,4r)-6'-фтор-n,n-диметил-4-фенил-4',9'-дигидро-3'h-спиро[циклогексан-1,1'-пирано-[3,4,b]индол]-4-амин и мелоксикам |
Country Status (22)
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| US (1) | US9308196B2 (enExample) |
| EP (1) | EP2849746B1 (enExample) |
| JP (1) | JP6116677B2 (enExample) |
| CN (2) | CN108451956A (enExample) |
| AU (1) | AU2013262076B2 (enExample) |
| BR (1) | BR112014028569A2 (enExample) |
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| EA (1) | EA026719B1 (enExample) |
| ES (1) | ES2659948T3 (enExample) |
| HR (1) | HRP20171843T1 (enExample) |
| HU (1) | HUE035122T2 (enExample) |
| IL (1) | IL235652B (enExample) |
| LT (1) | LT2849746T (enExample) |
| MX (1) | MX354685B (enExample) |
| NO (1) | NO2849746T3 (enExample) |
| PL (1) | PL2849746T3 (enExample) |
| PT (1) | PT2849746T (enExample) |
| RS (1) | RS56830B1 (enExample) |
| SI (1) | SI2849746T1 (enExample) |
| WO (1) | WO2013170970A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107427493A (zh) | 2015-01-23 | 2017-12-01 | 格吕伦塔尔有限公司 | 用于治疗肝功能受损和/或肾功能受损的受试者的疼痛的Cebranopadol |
| MX2018010367A (es) | 2016-02-29 | 2018-12-10 | Guenenthal Gmbh | Titulacion de cebranopadol. |
| GB202405898D0 (en) * | 2024-04-26 | 2024-06-12 | Univ Surrey | Mycobacterial infections |
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-
2013
- 2013-05-13 US US13/892,362 patent/US9308196B2/en active Active
- 2013-05-16 PL PL13724168T patent/PL2849746T3/pl unknown
- 2013-05-16 DK DK13724168.3T patent/DK2849746T3/en active
- 2013-05-16 HR HRP20171843TT patent/HRP20171843T1/hr unknown
- 2013-05-16 LT LTEP13724168.3T patent/LT2849746T/lt unknown
- 2013-05-16 JP JP2015511956A patent/JP6116677B2/ja active Active
- 2013-05-16 AU AU2013262076A patent/AU2013262076B2/en not_active Ceased
- 2013-05-16 WO PCT/EP2013/001469 patent/WO2013170970A1/en not_active Ceased
- 2013-05-16 EP EP13724168.3A patent/EP2849746B1/en not_active Not-in-force
- 2013-05-16 NO NO13724168A patent/NO2849746T3/no unknown
- 2013-05-16 HU HUE13724168A patent/HUE035122T2/en unknown
- 2013-05-16 CA CA2873863A patent/CA2873863A1/en not_active Abandoned
- 2013-05-16 CN CN201810667716.5A patent/CN108451956A/zh active Pending
- 2013-05-16 RS RS20180128A patent/RS56830B1/sr unknown
- 2013-05-16 PT PT137241683T patent/PT2849746T/pt unknown
- 2013-05-16 EA EA201401265A patent/EA026719B1/ru not_active IP Right Cessation
- 2013-05-16 ES ES13724168.3T patent/ES2659948T3/es active Active
- 2013-05-16 MX MX2014012862A patent/MX354685B/es active IP Right Grant
- 2013-05-16 SI SI201330919T patent/SI2849746T1/en unknown
- 2013-05-16 CN CN201380025679.3A patent/CN104302288A/zh active Pending
- 2013-05-16 BR BR112014028569A patent/BR112014028569A2/pt not_active IP Right Cessation
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2014
- 2014-11-12 IL IL235652A patent/IL235652B/en active IP Right Grant
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- 2018-01-24 CY CY20181100090T patent/CY1119824T1/el unknown
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| US20100297252A1 (en) * | 2003-03-03 | 2010-11-25 | Elan Pharma International Ltd. | Nanoparticulate meloxicam formulations |
| WO2005066183A1 (de) * | 2003-12-23 | 2005-07-21 | Grünenthal GmbH | Spirocyclische cyclohexan-derivate mit affinität zum orl1-rezeptor |
| US20080125475A1 (en) * | 2006-09-29 | 2008-05-29 | Grunenthal Gmbh | Mixed ORL1/mu-agonists for the treatment of pain |
| CN101327193A (zh) * | 2008-06-20 | 2008-12-24 | 海南锦瑞制药有限公司 | 一种氯诺昔康冻干粉针剂及其制备方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2015516450A (ja) | 2015-06-11 |
| JP6116677B2 (ja) | 2017-04-19 |
| LT2849746T (lt) | 2018-02-12 |
| IL235652A0 (en) | 2015-01-29 |
| CY1119824T1 (el) | 2018-06-27 |
| SI2849746T1 (en) | 2018-02-28 |
| AU2013262076B2 (en) | 2017-10-26 |
| US9308196B2 (en) | 2016-04-12 |
| NO2849746T3 (enExample) | 2018-04-14 |
| RS56830B1 (sr) | 2018-04-30 |
| MX2014012862A (es) | 2015-01-19 |
| ES2659948T3 (es) | 2018-03-20 |
| HRP20171843T1 (hr) | 2018-01-12 |
| CN104302288A (zh) | 2015-01-21 |
| HK1204939A1 (en) | 2015-12-11 |
| DK2849746T3 (en) | 2017-12-04 |
| CA2873863A1 (en) | 2013-11-21 |
| PL2849746T3 (pl) | 2018-04-30 |
| HUE035122T2 (en) | 2018-05-02 |
| EP2849746B1 (en) | 2017-11-15 |
| BR112014028569A2 (pt) | 2017-06-27 |
| PT2849746T (pt) | 2018-02-22 |
| EA201401265A1 (ru) | 2015-05-29 |
| CN108451956A (zh) | 2018-08-28 |
| WO2013170970A1 (en) | 2013-11-21 |
| US20130310371A1 (en) | 2013-11-21 |
| AU2013262076A1 (en) | 2015-01-22 |
| IL235652B (en) | 2018-08-30 |
| EP2849746A1 (en) | 2015-03-25 |
| MX354685B (es) | 2018-03-15 |
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| MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
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