HRP20171843T1 - Farmaceutski pripravak koji sadrži (1r,4r)-6'-fluoro-n,n-dimetil-4-fenil-4',9'-dihidro-3'h-spiro[cikloheksan-1,1'-pirano [3,4,b]indol]-4-amin i meloksikam - Google Patents

Farmaceutski pripravak koji sadrži (1r,4r)-6'-fluoro-n,n-dimetil-4-fenil-4',9'-dihidro-3'h-spiro[cikloheksan-1,1'-pirano [3,4,b]indol]-4-amin i meloksikam

Info

Publication number
HRP20171843T1
HRP20171843T1 HRP20171843TT HRP20171843T HRP20171843T1 HR P20171843 T1 HRP20171843 T1 HR P20171843T1 HR P20171843T T HRP20171843T T HR P20171843TT HR P20171843 T HRP20171843 T HR P20171843T HR P20171843 T1 HRP20171843 T1 HR P20171843T1
Authority
HR
Croatia
Prior art keywords
pirano
cyclohexan
meloxicam
indol
spiro
Prior art date
Application number
HRP20171843TT
Other languages
English (en)
Croatian (hr)
Inventor
Stefanie Frosch
Klaus Linz
Klaus Schiene
Original Assignee
Grünenthal GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Grünenthal GmbH filed Critical Grünenthal GmbH
Publication of HRP20171843T1 publication Critical patent/HRP20171843T1/hr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
HRP20171843TT 2012-05-18 2013-05-16 Farmaceutski pripravak koji sadrži (1r,4r)-6'-fluoro-n,n-dimetil-4-fenil-4',9'-dihidro-3'h-spiro[cikloheksan-1,1'-pirano [3,4,b]indol]-4-amin i meloksikam HRP20171843T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12003896 2012-05-18
EP13724168.3A EP2849746B1 (en) 2012-05-18 2013-05-16 Pharmaceutical composition comprising (1r,4r)-6'-fluoro-n,n-dimethyl-4-phenyl-4',9'-dihydro-3'h-spiro[cyclohexane-1,1'-pyrano [3,4,b]indol]-4-amine and meloxicam
PCT/EP2013/001469 WO2013170970A1 (en) 2012-05-18 2013-05-16 Pharmaceutical composition comprising (1r,4r)-6'-fluoro-n,n-dimethyl-4-phenyl-4',9'-dihydro-3'h-spiro[cyclohexane-1,1'-pyrano [3,4,b]indol]-4-amine and an oxicam

Publications (1)

Publication Number Publication Date
HRP20171843T1 true HRP20171843T1 (hr) 2018-01-12

Family

ID=48470899

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20171843TT HRP20171843T1 (hr) 2012-05-18 2013-05-16 Farmaceutski pripravak koji sadrži (1r,4r)-6'-fluoro-n,n-dimetil-4-fenil-4',9'-dihidro-3'h-spiro[cikloheksan-1,1'-pirano [3,4,b]indol]-4-amin i meloksikam

Country Status (22)

Country Link
US (1) US9308196B2 (enExample)
EP (1) EP2849746B1 (enExample)
JP (1) JP6116677B2 (enExample)
CN (2) CN104302288A (enExample)
AU (1) AU2013262076B2 (enExample)
BR (1) BR112014028569A2 (enExample)
CA (1) CA2873863A1 (enExample)
CY (1) CY1119824T1 (enExample)
DK (1) DK2849746T3 (enExample)
EA (1) EA026719B1 (enExample)
ES (1) ES2659948T3 (enExample)
HR (1) HRP20171843T1 (enExample)
HU (1) HUE035122T2 (enExample)
IL (1) IL235652B (enExample)
LT (1) LT2849746T (enExample)
MX (1) MX354685B (enExample)
NO (1) NO2849746T3 (enExample)
PL (1) PL2849746T3 (enExample)
PT (1) PT2849746T (enExample)
RS (1) RS56830B1 (enExample)
SI (1) SI2849746T1 (enExample)
WO (1) WO2013170970A1 (enExample)

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US10022353B2 (en) 2015-01-23 2018-07-17 Grünenthal GmbH Cebranopadol for treating pain in subjects with impaired hepatic and/or impaired renal function
WO2017148595A1 (en) 2016-02-29 2017-09-08 Grünenthal GmbH Titration of cebranopadol
GB202405898D0 (en) * 2024-04-26 2024-06-12 Univ Surrey Mycobacterial infections

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SI2012763T1 (sl) * 2006-04-28 2011-06-30 Gruenenthal Gmbh Farmacevtska kombinacija, ki obsega 3-(3-dimetilamino-1-etil-2-metil- propil)-fenol in NSAID
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MX2011002117A (es) * 2008-09-05 2011-03-28 Gruenenthal Gmbh Combinacion farmaceutica que comprenden 6-dimetilaminometil-1-(3-m etoxi-fenil)-ciclohexano-1,3-diol y un aines.
SI2331210T1 (sl) * 2008-09-05 2014-10-30 Gruenenthal Gmbh Farmacevtska kombinacija 3-(3-dimetilamino-1-etil-2-metil-propil)-fenola in antiepileptika
JP6010534B2 (ja) * 2010-08-04 2016-10-19 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング ６’−フルオロ−（Ｎ−メチル−又はＮ，Ｎ−ジメチル−）−４−フェニル−４’，９’−ジヒドロ−３’Ｈ−スピロ［シクロヘキサン−１，１’−ピラノ［３，４，ｂ］インドール］−４−アミンを含む医薬剤形
PL2600838T3 (pl) * 2010-08-04 2016-02-29 Gruenenthal Gmbh Farmaceutyczna postać dawkowania zawierająca 6'-fluoro-(N-metylo- lub N,N-dimetylo)-4-fenylo-4'9'-dihydro-3'H-spiro[cykloheksano-1,1'-pirano[3,4b]indolo]-4-aminę
EP2600850B1 (en) * 2010-08-04 2018-10-17 Grünenthal GmbH Pharmaceutical dosage form comprising 6'-fluoro-(n-methyl- or n,n-dimethyl-)-4-phenyl-4',9'-dihydro-3'h-spiro[cyclohexane-1,1'-pyrano[3,4,b]indol]-4-amine for the treatment of nociceptive pain

Also Published As

Publication number Publication date
RS56830B1 (sr) 2018-04-30
US9308196B2 (en) 2016-04-12
BR112014028569A2 (pt) 2017-06-27
EP2849746B1 (en) 2017-11-15
EA201401265A1 (ru) 2015-05-29
JP2015516450A (ja) 2015-06-11
EA026719B1 (ru) 2017-05-31
LT2849746T (lt) 2018-02-12
CY1119824T1 (el) 2018-06-27
HK1204939A1 (en) 2015-12-11
NO2849746T3 (enExample) 2018-04-14
SI2849746T1 (en) 2018-02-28
CN104302288A (zh) 2015-01-21
ES2659948T3 (es) 2018-03-20
HUE035122T2 (en) 2018-05-02
PL2849746T3 (pl) 2018-04-30
WO2013170970A1 (en) 2013-11-21
MX2014012862A (es) 2015-01-19
AU2013262076A1 (en) 2015-01-22
PT2849746T (pt) 2018-02-22
MX354685B (es) 2018-03-15
JP6116677B2 (ja) 2017-04-19
DK2849746T3 (en) 2017-12-04
EP2849746A1 (en) 2015-03-25
CA2873863A1 (en) 2013-11-21
US20130310371A1 (en) 2013-11-21
CN108451956A (zh) 2018-08-28
AU2013262076B2 (en) 2017-10-26
IL235652A0 (en) 2015-01-29
IL235652B (en) 2018-08-30

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HRP20171843T1 (hr) Farmaceutski pripravak koji sadrži (1r,4r)-6'-fluoro-n,n-dimetil-4-fenil-4',9'-dihidro-3'h-spiro[cikloheksan-1,1'-pirano [3,4,b]indol]-4-amin i meloksikam
ZA201300038B (en) Pharmaceutical dosage form comprising 6'-fluoro-(n-methyl-or n,n-dimethyl-)-4-phenyl-4,9'-dihydro-3'h-spiro[cyclohexane-1,1'-pyrano[3,4,b]indol]-4-amine
IL235653A0 (en) A pharmaceutical preparation containing (1r, 4r) - 6' - fluoro - n, n - dimethyl - 4 - phenyl - 4', 9' - dihydro - 3'h - spiro [cyclohexane - 1, 1' - pyrano [3, 4 ,b] indole] – 4 – amine and a non-steroidal anti-rheumatic drug
IL235657B (en) Pharmacy device containing (1r, 4r) - 6' - fluoro - n, n - dimethyl - 4 - phenyl - 4', 9' - dihydro - 3'h - spiro [cyclohexane - 1, 1' - pyrano [3, 4 ,b] indole] – 4 – amine and antidepressants
IL235651A0 (en) A pharmaceutical preparation containing (1r, 4r) - 6' - fluoro - n, n - dimethyl - 4 - phenyl - 4', 9' - dihydro - 3'h - spiro [cyclohexane - 1, 1' - pyrano [3, 4 ,b] Indole] - 4 - amine and paracetamol or propacetamol
IL235656B (en) A pharmaceutical preparation containing (1r, 4r) - 6' - fluoro - n, n - dimethyl - 4 - phenyl - 4', 9' - dihydro - 3'h - spiro [cyclohexane - 1, 1' - pyrano [3, 4 ,b] Indole] - 4 - amine and a component of salicylic acid