JP2015512938A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2015512938A5 JP2015512938A5 JP2015505769A JP2015505769A JP2015512938A5 JP 2015512938 A5 JP2015512938 A5 JP 2015512938A5 JP 2015505769 A JP2015505769 A JP 2015505769A JP 2015505769 A JP2015505769 A JP 2015505769A JP 2015512938 A5 JP2015512938 A5 JP 2015512938A5
- Authority
- JP
- Japan
- Prior art keywords
- triblock copolymer
- protected
- micelle
- independently
- formula vii
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261622755P | 2012-04-11 | 2012-04-11 | |
| US61/622,755 | 2012-04-11 | ||
| US201261659841P | 2012-06-14 | 2012-06-14 | |
| US61/659,841 | 2012-06-14 | ||
| PCT/US2013/032409 WO2013154774A1 (en) | 2012-04-11 | 2013-03-15 | Block copolymers for stable micelles |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015162006A Division JP6466283B2 (ja) | 2012-04-11 | 2015-08-19 | 安定なミセルのためのブロックコポリマー |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015512938A JP2015512938A (ja) | 2015-04-30 |
| JP2015512938A5 true JP2015512938A5 (https=) | 2015-10-08 |
| JP5927338B2 JP5927338B2 (ja) | 2016-06-01 |
Family
ID=47901746
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015505769A Expired - Fee Related JP5927338B2 (ja) | 2012-04-11 | 2013-03-15 | 安定なミセルのためのブロックコポリマー |
| JP2015162006A Active JP6466283B2 (ja) | 2012-04-11 | 2015-08-19 | 安定なミセルのためのブロックコポリマー |
| JP2019001801A Expired - Fee Related JP6740391B2 (ja) | 2012-04-11 | 2019-01-09 | 安定なミセルのためのブロックコポリマー |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015162006A Active JP6466283B2 (ja) | 2012-04-11 | 2015-08-19 | 安定なミセルのためのブロックコポリマー |
| JP2019001801A Expired - Fee Related JP6740391B2 (ja) | 2012-04-11 | 2019-01-09 | 安定なミセルのためのブロックコポリマー |
Country Status (12)
| Country | Link |
|---|---|
| US (6) | US20130296531A1 (https=) |
| EP (2) | EP2660255B1 (https=) |
| JP (3) | JP5927338B2 (https=) |
| KR (1) | KR101607422B1 (https=) |
| CN (2) | CN104487481B (https=) |
| AU (1) | AU2013201541B2 (https=) |
| CA (1) | CA2868274C (https=) |
| ES (1) | ES2560235T3 (https=) |
| IL (1) | IL235003A (https=) |
| MX (1) | MX340992B (https=) |
| NZ (2) | NZ709953A (https=) |
| WO (1) | WO2013154774A1 (https=) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012019168A2 (en) | 2010-08-06 | 2012-02-09 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
| RU2013120302A (ru) | 2010-10-01 | 2014-11-20 | Модерна Терапьютикс, Инк. | Сконструированные нуклеиновые кислоты и способы их применения |
| EP2691101A2 (en) | 2011-03-31 | 2014-02-05 | Moderna Therapeutics, Inc. | Delivery and formulation of engineered nucleic acids |
| US9464124B2 (en) | 2011-09-12 | 2016-10-11 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
| RU2648950C2 (ru) | 2011-10-03 | 2018-04-02 | Модерна Терапьютикс, Инк. | Модифицированные нуклеозиды, нуклеотиды и нуклеиновые кислоты и их применение |
| CN104114572A (zh) | 2011-12-16 | 2014-10-22 | 现代治疗公司 | 经修饰的核苷、核苷酸和核酸组合物 |
| AU2013243948A1 (en) | 2012-04-02 | 2014-10-30 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of proteins associated with human disease |
| US9283287B2 (en) | 2012-04-02 | 2016-03-15 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of nuclear proteins |
| US9254311B2 (en) | 2012-04-02 | 2016-02-09 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of proteins |
| US9572897B2 (en) | 2012-04-02 | 2017-02-21 | Modernatx, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
| US20140127271A1 (en) * | 2012-04-11 | 2014-05-08 | Intezyne Technologies, Inc. | Block copolymers for stable micelles |
| CA2868274C (en) | 2012-04-11 | 2021-05-25 | Intezyne Technologies, Inc. | Block copolymers for stable micelles |
| US20140113879A1 (en) * | 2012-04-11 | 2014-04-24 | Intezyne Technologies, Inc. | Block copolymers for stable micelles |
| US9944752B2 (en) | 2012-04-11 | 2018-04-17 | Intezyne Technologies, Inc. | Block copolymers for stable micelles |
| US20140114051A1 (en) * | 2012-04-11 | 2014-04-24 | Intezyne Technologies, Inc. | Block copolymers for stable micelles |
| WO2014081507A1 (en) | 2012-11-26 | 2014-05-30 | Moderna Therapeutics, Inc. | Terminally modified rna |
| EP2971010B1 (en) | 2013-03-14 | 2020-06-10 | ModernaTX, Inc. | Formulation and delivery of modified nucleoside, nucleotide, and nucleic acid compositions |
| US8980864B2 (en) | 2013-03-15 | 2015-03-17 | Moderna Therapeutics, Inc. | Compositions and methods of altering cholesterol levels |
| JP2016538829A (ja) | 2013-10-03 | 2016-12-15 | モデルナ セラピューティクス インコーポレイテッドＭｏｄｅｒｎａ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． | 低密度リポタンパク質受容体をコードするポリヌクレオチド |
| CN104856973A (zh) * | 2014-02-25 | 2015-08-26 | 苏州雷纳药物研发有限公司 | 一种卡巴他赛胶束载药系统及其制备方法 |
| CN105640882A (zh) * | 2015-10-16 | 2016-06-08 | 姚俊华 | 一种卡巴他赛胶束载药系统及其制备方法和应用 |
| CN109476841B (zh) * | 2016-07-30 | 2021-08-24 | 日本化药株式会社 | 新型高分子衍生物和使用其的新型高分子衍生物成像探针 |
| JPWO2018025699A1 (ja) * | 2016-08-02 | 2019-05-30 | 日本化薬株式会社 | アクティブターゲティング型高分子誘導体、その高分子誘導体を含む組成物、及びそれらの用途 |
| WO2018088541A1 (ja) * | 2016-11-11 | 2018-05-17 | 国立大学法人北陸先端科学技術大学院大学 | 薬物放出制御用ハイドロゲル及びその製造方法 |
| US10143689B2 (en) | 2017-02-08 | 2018-12-04 | Interzyne Technologies, Inc. | SN-38 loaded iron crosslinked micelle and methods thereof |
| WO2018187515A1 (en) | 2017-04-04 | 2018-10-11 | Avidea Technologies, Inc. | Peptide-based vaccines, methods of manufacturing, and uses thereof for inducing an immune response |
| US11786607B2 (en) | 2017-06-15 | 2023-10-17 | Modernatx, Inc. | RNA formulations |
| WO2019013814A1 (en) | 2017-07-14 | 2019-01-17 | Hewlett-Packard Development Company, L.P. | 3D PRINTING |
| WO2019046809A1 (en) | 2017-08-31 | 2019-03-07 | Modernatx, Inc. | METHODS OF MANUFACTURING LIPID NANOPARTICLES |
| WO2019104001A1 (en) * | 2017-11-22 | 2019-05-31 | Hillstream Biopharma Inc. | Polymeric nanoparticles comprising bortezomib |
| CN113271926A (zh) | 2018-09-20 | 2021-08-17 | 摩登纳特斯有限公司 | 脂质纳米颗粒的制备及其施用方法 |
| US12435048B2 (en) | 2018-09-28 | 2025-10-07 | Lonza Ltd | Method for preparation of n-carboxyanhydrides |
| CA3113782A1 (en) * | 2018-10-03 | 2020-04-09 | Avidea Technologies, Inc. | Aromatic ring substituted amphiphilic polymers as drug delivery systems |
| CN109762150B (zh) * | 2018-12-14 | 2020-09-22 | 华南理工大学 | 一种具有内在荧光特性可降解生物医用材料及其制备方法 |
| EP3943182A4 (en) | 2019-03-20 | 2022-05-25 | Mitsubishi Chemical Corporation | POLYMER, RELEASING AGENT, METHOD OF MAKING A POLYMER, METHOD OF SEPARATING A JOINT AND METHOD OF MAKING A JOINT |
| CN110105562B (zh) * | 2019-04-23 | 2021-10-12 | 华东师范大学 | 含多巴胺配体的两嵌段聚合物及其合成方法和应用 |
| US11541007B2 (en) * | 2019-05-16 | 2023-01-03 | Megapro Biomedical Co., Ltd. | Pharmaceutical compositions containing mixed polymeric micelles |
| US11857630B2 (en) | 2020-01-10 | 2024-01-02 | Tyndall Formulation Services, LLC | Formulations of SN-38 with poly(amino acid) block polymers |
| BR112022013685A2 (pt) | 2020-01-10 | 2022-09-06 | R Pharm Us Operating Llc | Composições de ixabepilona |
| US10836869B1 (en) | 2020-01-10 | 2020-11-17 | Tyndall Formulation Services, LLC | Polymer excipients for drug delivery applications |
| US11286344B2 (en) | 2020-01-10 | 2022-03-29 | Tyndall Formulation Services, LLC | Polymer excipients for drug delivery applications |
| IL294481B2 (en) * | 2020-01-10 | 2026-02-01 | Tyndall Formulation Services Llc | Polymeric excipients for drug delivery applications |
| US10918619B1 (en) | 2020-01-10 | 2021-02-16 | Tyndall Formulation Services, LLC | Formulations of paclitaxel with poly(amino acid) block polymers |
| JP7560274B2 (ja) * | 2020-06-08 | 2024-10-02 | 公益財団法人川崎市産業振興財団 | 共重合体、該共重合体の製造方法、およびカルボキシ基またはその塩を有する共重合体の製造方法 |
| CN112190565B (zh) * | 2020-10-27 | 2022-06-14 | 华南理工大学 | 一种能减轻吉非替尼毒性的肾靶向纳米粒子及其制备方法 |
| JP7604878B2 (ja) * | 2020-12-22 | 2024-12-24 | Dic株式会社 | 構造色発現用組成物 |
| CN115368560B (zh) * | 2022-08-26 | 2023-11-14 | 天津大学 | 聚乙二醇-嵌段-聚甲硫氨酸-接枝-海藻糖聚合物及制备方法和应用 |
| KR102640099B1 (ko) * | 2022-11-17 | 2024-02-23 | 주식회사 삼양홀딩스 | 조직 수복용 분말 제형 및 이를 포함하는 조직 수복용 주사제 조성물 |
| IT202300015291A1 (it) * | 2023-07-20 | 2025-01-20 | Fond Riccardo Terzi E Silvio Albini | Sistema di rilascio comprendente nanoparticelle lipidiche o polimeriche comprendenti ormoni tiroidei |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2002224526A1 (en) * | 2000-07-24 | 2002-02-05 | Ono Pharmaceutical Co. Ltd. | Freeze-dried preparation of n-(o-(p-pivaloyloxybenzenesulfonylamino)benzoyl)glycine monosodium salt tetrahydrate and process for producing the same |
| CA2584510C (en) | 2004-10-25 | 2013-05-28 | Intezyne Technologies, Incorporated | Heterobifunctional poly(ethylene glycol) and uses thereof |
| EP2067801A1 (en) | 2005-01-04 | 2009-06-10 | Intezyne Technologies Incorporated | Synthesis of Hybrid Block Copolymers |
| DE602006008625D1 (de) | 2005-04-01 | 2009-10-01 | Intezyne Technologies Inc | Polymermicellen für die arzneistoffzufuhr |
| US8759465B2 (en) * | 2006-04-25 | 2014-06-24 | Purdue Research Foundation | Cross-linkable polymeric compositions |
| US20090110662A1 (en) | 2007-04-30 | 2009-04-30 | Intezyne Technologies, Inc. | Modification of biological targeting groups for the treatment of cancer |
| EP2359862B1 (en) * | 2007-04-30 | 2013-07-24 | Intezyne Technologies Inc. | Hybrid block copolymer micelles with mixed stereochemistry for encapsulation of hydrophobic agents |
| WO2010127159A2 (en) * | 2009-04-30 | 2010-11-04 | Intezyne Technologies, Incorporated | Polymeric micelles for polynucleotide encapsulation |
| CA2760771A1 (en) * | 2009-05-04 | 2010-11-11 | Intezyne Technologies, Incorporated | Polymer micelles containing sn-38 for the treatment of cancer |
| US8609146B2 (en) * | 2011-09-19 | 2013-12-17 | Intezyne Technologies, Inc. | Multi-block copolymers for the preparation of stabilized micelles |
| US20140114051A1 (en) * | 2012-04-11 | 2014-04-24 | Intezyne Technologies, Inc. | Block copolymers for stable micelles |
| CA2868274C (en) | 2012-04-11 | 2021-05-25 | Intezyne Technologies, Inc. | Block copolymers for stable micelles |
| US20140113879A1 (en) | 2012-04-11 | 2014-04-24 | Intezyne Technologies, Inc. | Block copolymers for stable micelles |
| US9944752B2 (en) | 2012-04-11 | 2018-04-17 | Intezyne Technologies, Inc. | Block copolymers for stable micelles |
| US20140127271A1 (en) * | 2012-04-11 | 2014-05-08 | Intezyne Technologies, Inc. | Block copolymers for stable micelles |
-
2013
- 2013-03-15 CA CA2868274A patent/CA2868274C/en active Active
- 2013-03-15 NZ NZ709953A patent/NZ709953A/en not_active IP Right Cessation
- 2013-03-15 JP JP2015505769A patent/JP5927338B2/ja not_active Expired - Fee Related
- 2013-03-15 CN CN201380023578.2A patent/CN104487481B/zh not_active Expired - Fee Related
- 2013-03-15 CN CN201610908380.8A patent/CN106511270A/zh active Pending
- 2013-03-15 AU AU2013201541A patent/AU2013201541B2/en not_active Ceased
- 2013-03-15 MX MX2014011980A patent/MX340992B/es active IP Right Grant
- 2013-03-15 WO PCT/US2013/032409 patent/WO2013154774A1/en not_active Ceased
- 2013-03-15 US US13/839,715 patent/US20130296531A1/en not_active Abandoned
- 2013-03-15 US US13/840,133 patent/US9078930B2/en active Active
- 2013-03-15 EP EP13001333.7A patent/EP2660255B1/en active Active
- 2013-03-15 ES ES13001333.7T patent/ES2560235T3/es active Active
- 2013-03-15 EP EP15191496.7A patent/EP3000833B1/en active Active
- 2013-03-15 NZ NZ700397A patent/NZ700397A/en not_active IP Right Cessation
- 2013-03-15 KR KR1020147028330A patent/KR101607422B1/ko not_active Expired - Fee Related
- 2013-03-15 US US13/839,994 patent/US20130288991A1/en not_active Abandoned
-
2014
- 2014-10-06 IL IL235003A patent/IL235003A/en active IP Right Grant
-
2015
- 2015-04-23 US US14/694,760 patent/US9499665B2/en active Active
- 2015-08-19 JP JP2015162006A patent/JP6466283B2/ja active Active
-
2016
- 2016-09-28 US US15/279,042 patent/US10047197B2/en active Active
- 2016-09-28 US US15/279,017 patent/US9944754B2/en active Active
-
2019
- 2019-01-09 JP JP2019001801A patent/JP6740391B2/ja not_active Expired - Fee Related
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2015512938A5 (https=) | ||
| HRP20200407T1 (hr) | Terapeutske polimerne nanočestice i postupci dobivanja i korištenja istih | |
| CY1123545T1 (el) | Ν-σουλφονυλιωμενα πυραζολο[3,4-β]πυριδιν-6-καρβοξαμιδια και μεθοδος χρησης | |
| IL284363A (en) | Rna-editing oligonucleotides for the treatment of usher syndrome | |
| JP2015214584A5 (https=) | ||
| CY1119771T1 (el) | Ενωσεις αμινοπυριμιδινυλιου ως αναστολεις toy jak | |
| JP2019523214A5 (https=) | ||
| EP4420679A3 (en) | Lipids and lipid nanoparticle formulations for delivery of nucleic acids | |
| JP2017517520A5 (https=) | ||
| WO2017044507A3 (en) | Sirna/nanoparticle formulations for treatment of middle-east respiratory syndrome coronaviral infection | |
| HRP20201812T1 (hr) | Modulatori proteina jezgre hepatitisa b | |
| WO2015106128A3 (en) | Rnai agents modified at the 4'-c-position | |
| JOP20170135A1 (ar) | مركبات ديازاسبيروألكيل مثيل-إندول | |
| CY1117067T1 (el) | Η χρηση σωματιδιων στερεων φορεων για τη βελτιωση της επεξεργασιμοτητας φαρμακευτικου παραγοντα | |
| JP2013510123A5 (https=) | ||
| JP2019521180A5 (https=) | ||
| PE20170312A1 (es) | Nanoparticulas terapeuticas que comprenden un agente terapeutico, y metodos para su elaboracion y uso | |
| ATE536172T1 (de) | Ezetimibzusammensetzungen | |
| JP2012504133A5 (https=) | ||
| NZ741291A (en) | Stabilizing camptothecin pharmaceutical compositions | |
| JP2016540015A5 (https=) | ||
| CY1124316T1 (el) | Κρυσταλλικο τοσυλικο αλας ενος ρι3κ δελτα εκλεκτικου αναστολεα για χρηση σε φαρμακευτικα σκευασματα | |
| EA201891575A1 (ru) | Составы для лечения рака мочевого пузыря | |
| CO2019004190A2 (es) | Formulaciones liposomales para uso en el tratamiento del cáncer | |
| EA202090978A1 (ru) | Новые макроциклические производные, способ их получения и содержащие их фармацевтические композиции |