JP2015512893A5 - - Google Patents

Info

Publication number

JP2015512893A5

JP2015512893A5 JP2014561473A JP2014561473A JP2015512893A5 JP 2015512893 A5 JP2015512893 A5 JP 2015512893A5 JP 2014561473 A JP2014561473 A JP 2014561473A JP 2014561473 A JP2014561473 A JP 2014561473A JP 2015512893 A5 JP2015512893 A5 JP 2015512893A5

Authority

JP

Japan

Prior art keywords

polypeptide

albumin

fragment

fusion

fcrn

Prior art date

2013-03-15

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
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• 108090000765 processed proteins & peptides Proteins 0.000 claims 48
• 229920001184 polypeptide Polymers 0.000 claims 47
• 102000004196 processed proteins & peptides Human genes 0.000 claims 47
• 102000009027 Albumins Human genes 0.000 claims 35
• 108010088751 Albumins Proteins 0.000 claims 35
• 239000012634 fragment Substances 0.000 claims 27
• 230000004927 fusion Effects 0.000 claims 25
• 102100026120 IgG receptor FcRn large subunit p51 Human genes 0.000 claims 11
• 101710177940 IgG receptor FcRn large subunit p51 Proteins 0.000 claims 11
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 7
• 230000004048 modification Effects 0.000 claims 7
• 238000012986 modification Methods 0.000 claims 7
• 238000000034 method Methods 0.000 claims 6
• 239000011859 microparticle Substances 0.000 claims 6
• 239000000203 mixture Substances 0.000 claims 6
• 239000002105 nanoparticle Substances 0.000 claims 6
• 150000007523 nucleic acids Chemical class 0.000 claims 5
• 108020004707 nucleic acids Proteins 0.000 claims 4
• 102000039446 nucleic acids Human genes 0.000 claims 4
• 230000009286 beneficial effect Effects 0.000 claims 3
• 230000000069 prophylactic effect Effects 0.000 claims 3
• 230000001225 therapeutic effect Effects 0.000 claims 3
• 239000002131 composite material Substances 0.000 claims 2
• 239000001963 growth medium Substances 0.000 claims 2
• 238000003384 imaging method Methods 0.000 claims 2
• 108091028043 Nucleic acid sequence Proteins 0.000 claims 1
• 238000012258 culturing Methods 0.000 claims 1
• 230000003389 potentiating effect Effects 0.000 claims 1