JP2015511948A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2015511948A5 JP2015511948A5 JP2014557782A JP2014557782A JP2015511948A5 JP 2015511948 A5 JP2015511948 A5 JP 2015511948A5 JP 2014557782 A JP2014557782 A JP 2014557782A JP 2014557782 A JP2014557782 A JP 2014557782A JP 2015511948 A5 JP2015511948 A5 JP 2015511948A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- target
- composition
- vector
- polypeptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920001184 polypeptide Polymers 0.000 claims 11
- 102000004196 processed proteins & peptides Human genes 0.000 claims 11
- 108090000765 processed proteins & peptides Proteins 0.000 claims 11
- 239000013598 vector Substances 0.000 claims 9
- 102000004473 OX40 Ligand Human genes 0.000 claims 7
- 108010042215 OX40 Ligand Proteins 0.000 claims 7
- 206010037742 Rabies Diseases 0.000 claims 7
- 241000283690 Bos taurus Species 0.000 claims 4
- 241000282326 Felis catus Species 0.000 claims 4
- 241001465754 Metazoa Species 0.000 claims 4
- 241001494479 Pecora Species 0.000 claims 3
- 102000040430 polynucleotide Human genes 0.000 claims 3
- 108091033319 polynucleotide Proteins 0.000 claims 3
- 239000002157 polynucleotide Substances 0.000 claims 3
- 241000120516 African horse sickness virus Species 0.000 claims 2
- 241000713800 Feline immunodeficiency virus Species 0.000 claims 2
- 241000711475 Feline infectious peritonitis virus Species 0.000 claims 2
- 241000704611 Fig cryptic virus Species 0.000 claims 2
- 241000710198 Foot-and-mouth disease virus Species 0.000 claims 2
- 241001533430 Leishmaniavirus Species 0.000 claims 2
- 241000526636 Nipah henipavirus Species 0.000 claims 2
- 241001673669 Porcine circovirus 2 Species 0.000 claims 2
- 241001135989 Porcine reproductive and respiratory syndrome virus Species 0.000 claims 2
- 241000711975 Vesicular stomatitis virus Species 0.000 claims 2
- 241000700605 Viruses Species 0.000 claims 2
- 241000710886 West Nile virus Species 0.000 claims 2
- 239000013604 expression vector Substances 0.000 claims 2
- 239000012634 fragment Substances 0.000 claims 2
- 206010022000 influenza Diseases 0.000 claims 2
- 208000032839 leukemia Diseases 0.000 claims 2
- 241000894007 species Species 0.000 claims 2
- 241000893570 Hendra henipavirus Species 0.000 claims 1
- 241000288906 Primates Species 0.000 claims 1
- 230000001900 immune effect Effects 0.000 claims 1
- 238000001727 in vivo Methods 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261598610P | 2012-02-14 | 2012-02-14 | |
| US61/598,610 | 2012-02-14 | ||
| PCT/US2013/026206 WO2013123242A1 (en) | 2012-02-14 | 2013-02-14 | Recombinant poxviral vectors expressing both rabies and ox40 proteins, and vaccines made therefrom |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015511948A JP2015511948A (ja) | 2015-04-23 |
| JP2015511948A5 true JP2015511948A5 (enExample) | 2016-03-03 |
| JP6260972B2 JP6260972B2 (ja) | 2018-01-17 |
Family
ID=47757705
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014557782A Expired - Fee Related JP6260972B2 (ja) | 2012-02-14 | 2013-02-14 | 狂犬病タンパク質及びｏｘ４０タンパク質の両方を発現する組換えポックスウイルスベクター並びに前記ベクターから製造されるワクチン |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US9567606B2 (enExample) |
| EP (2) | EP2814506B1 (enExample) |
| JP (1) | JP6260972B2 (enExample) |
| CN (1) | CN104203271B (enExample) |
| AU (1) | AU2013221502C1 (enExample) |
| BR (1) | BR112014020019A8 (enExample) |
| CA (1) | CA2864119C (enExample) |
| EA (1) | EA032389B1 (enExample) |
| ES (2) | ES2723273T3 (enExample) |
| MX (1) | MX360415B (enExample) |
| NZ (2) | NZ722700A (enExample) |
| WO (1) | WO2013123242A1 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009111738A2 (en) | 2008-03-06 | 2009-09-11 | Mayo Foundation For Medical Education And Research | Single cycle replicating adenovirus vectors |
| US9567606B2 (en) | 2012-02-14 | 2017-02-14 | Merial Inc. | Recombinant poxviral vectors expressing both rabies and OX40 proteins, and vaccines made therefrom |
| US9974845B2 (en) | 2013-02-22 | 2018-05-22 | Curevac Ag | Combination of vaccination and inhibition of the PD-1 pathway |
| US10196435B2 (en) * | 2013-11-18 | 2019-02-05 | University Of Southern California | OX40L fusion protein for the immunotherapy of tumors of veterinary animals |
| MX375528B (es) | 2013-12-20 | 2025-03-06 | Boehringer Ingelheim Vetmedica Gmbh | Variante del virus prrs, clon de adnc del virus europeo y sus usos. |
| CN103877570B (zh) * | 2014-02-19 | 2016-01-20 | 北京中联康生物科技有限公司 | 狂犬病活疫苗和制备狂犬病口服活疫苗的方法 |
| ES2754239T3 (es) | 2014-03-12 | 2020-04-16 | Curevac Ag | Combinación de vacunación y agonistas de OX40 |
| US10010499B2 (en) | 2014-11-03 | 2018-07-03 | Merial Inc. | Methods of using microneedle vaccine formulations to elicit in animals protective immunity against rabies virus |
| SG11201705844SA (en) | 2015-02-06 | 2017-08-30 | Heat Biologics Inc | Vector co-expressing vaccine and costimulatory molecules |
| DK3458474T3 (da) | 2016-05-18 | 2022-09-26 | Modernatx Inc | Kombinationer af mrna'er, der koder for immunmodulerende polypeptider og anvendelser deraf |
| US11666649B2 (en) | 2016-10-11 | 2023-06-06 | University Of Miami | Vectors and vaccine cells for immunity against Zika virus |
| CA3058938A1 (en) | 2017-04-04 | 2018-10-11 | Heat Biologics, Inc. | Intratumoral vaccination |
| CA3088646A1 (en) | 2018-02-23 | 2019-08-29 | Boehringer Ingelheim Vetmedica Gmbh | Recombinant viral vector systems expressing exogenous feline paramyxovirus genes and vaccines made therefrom |
| US12042527B2 (en) | 2019-01-08 | 2024-07-23 | Modernatx, Inc. | Use of mRNAs encoding OX40L, IL-23 and IL-36gamma in combination with immune checkpoint blockade for treating particular cancers |
| CN111518776A (zh) * | 2020-04-16 | 2020-08-11 | 大理大学 | 一种重组狂犬病病毒疫苗株及其制备方法 |
| GB202012331D0 (en) * | 2020-08-07 | 2020-09-23 | Petmedix Ltd | Therapeutic antibodies |
| US11149286B1 (en) * | 2020-08-17 | 2021-10-19 | Mayo Foundation For Medical Education And Research | Adenovirus vectors and methods for using adenovirus vectors |
| EP4476256A1 (en) * | 2022-02-09 | 2024-12-18 | Petmedix Ltd. | Therapeutic antibodies |
| CN116656730B (zh) * | 2023-05-25 | 2024-03-19 | 军事科学院军事医学研究院军事兽医研究所 | 一种表达狂犬病病毒g、m蛋白的重组金丝雀痘病毒及其构建方法 |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2909462A (en) | 1955-12-08 | 1959-10-20 | Bristol Myers Co | Acrylic acid polymer laxative compositions |
| US5505941A (en) | 1981-12-24 | 1996-04-09 | Health Research, Inc. | Recombinant avipox virus and method to induce an immune response |
| US4708871A (en) | 1983-03-08 | 1987-11-24 | Commonwealth Serum Laboratories Commission | Antigenically active amino acid sequences |
| DE3584341D1 (de) | 1984-08-24 | 1991-11-14 | Upjohn Co | Rekombinante dna-verbindungen und expression von polypeptiden wie tpa. |
| AU672359B2 (en) * | 1991-03-07 | 1996-10-03 | Virogenetics Corporation | Genetically engineered vaccine strain |
| US6309647B1 (en) | 1999-07-15 | 2001-10-30 | Aventis Pasteur | Poxvirus—canine dispemper virus (CDV) or measles virus recombinants and compositions and methods employing the recombinants |
| US5756102A (en) | 1990-11-20 | 1998-05-26 | Virogenetics Corporation | Poxvirus-canine distemper virus (CDV) recombinants and compositions and methods employing the recombinants |
| US5843456A (en) | 1991-03-07 | 1998-12-01 | Virogenetics Corporation | Alvac poxvirus-rabies compositions and combination compositions and uses |
| FR2724385B1 (fr) | 1994-08-29 | 1996-12-13 | Rhone Merieux | Vaccin de la peritonite infectieuse feline. |
| EP0826063A1 (en) | 1995-04-25 | 1998-03-04 | Vical Incorporated | Single-vial formulations of dna/lipid complexes |
| US5846946A (en) | 1996-06-14 | 1998-12-08 | Pasteur Merieux Serums Et Vaccins | Compositions and methods for administering Borrelia DNA |
| FR2751227B1 (fr) | 1996-07-19 | 1998-11-27 | Rhone Merieux | Formule de vaccin polynucleotidique contre les pathologies canines, notamment les pathologies respiratoires et digestives |
| FR2751224B1 (fr) | 1996-07-19 | 1998-11-20 | Rhone Merieux | Formule de vaccin polynucleotidique contre les pathologies respiratoires et de reproduction des porcs |
| FR2751226B1 (fr) | 1996-07-19 | 1998-11-27 | Rhone Merieux | Formule de vaccin polynucleotidique contre les pathologies du cheval |
| FR2751225B1 (fr) | 1996-07-19 | 1998-11-27 | Rhone Merieux | Formule de vaccin polynucleotidique aviaire |
| FR2751229B1 (fr) | 1996-07-19 | 1998-11-27 | Rhone Merieux | Formule de vaccin polynucleotidique notamment contre la pathologie respiratoire des bovins |
| FR2751228B1 (fr) | 1996-07-19 | 1998-11-20 | Rhone Merieux | Vaccin polynucleotidique bovin pour voie intradermique |
| CA2294793A1 (fr) | 1997-06-30 | 1999-01-14 | Rhone-Poulenc Rorer S.A. | Amelioration du transfert d'acide nucleique dans le muscle strie et combinaison permettant la mise en oeuvre du procede |
| FR2775601B1 (fr) | 1998-03-03 | 2001-09-21 | Merial Sas | Vaccins vivants recombines et adjuves |
| US6497883B1 (en) | 1999-06-10 | 2002-12-24 | Merial | Porcine circovirus recombinant poxvirus vaccine |
| US6541458B1 (en) | 1999-07-16 | 2003-04-01 | Merial | Feline calicivirus genes and vaccines in particular recombinant vaccines |
| US6852705B2 (en) | 2000-01-21 | 2005-02-08 | Merial | DNA vaccines for farm animals, in particular bovines and porcines |
| JP2004517057A (ja) * | 2000-11-03 | 2004-06-10 | オックスフォード バイオメディカ（ユーケイ）リミテッド | ベクターシステム |
| US7740863B2 (en) | 2001-04-06 | 2010-06-22 | Merial | Recombinant vaccine against West Nile Virus |
| US7582302B2 (en) | 2004-06-04 | 2009-09-01 | Merial Limited | Needle-free administration of FeLV vaccines |
| DK1773387T3 (da) | 2004-06-25 | 2013-07-15 | Merial Ltd | Avipox-rekombinanter der udtrykker mund- og klovesyge-virusgener |
| US8980280B2 (en) | 2005-03-30 | 2015-03-17 | Merial, Inc. | Recombinant feline leukemia virus vaccine containing optimized feline leukemia virus envelope gene |
| SI1881845T1 (sl) | 2005-04-25 | 2010-06-30 | Merial Ltd | Cepiva proti virusu Nipah |
| US7384642B2 (en) | 2005-08-25 | 2008-06-10 | Merial Limited | Canine influenza vaccines |
| US7862821B2 (en) | 2006-06-01 | 2011-01-04 | Merial Limited | Recombinant vaccine against bluetongue virus |
| US8008268B2 (en) | 2006-07-25 | 2011-08-30 | Merial Limited | Vaccines against vesicular stomatitis |
| US7910112B2 (en) | 2006-11-06 | 2011-03-22 | Merial Limited | Feline vaccines against avian influenza |
| CA2670097C (en) | 2006-11-21 | 2015-10-06 | Merial Limited | Prime boost canine leishmania vaccine |
| BRPI0920622B1 (pt) | 2008-10-24 | 2019-11-12 | Merial, Inc. | vacina contra o vírus da doença equina africana |
| CN101884793A (zh) * | 2010-06-29 | 2010-11-17 | 中国人民解放军第三军医大学 | 乙肝病毒核心抗原的免疫增强型基因疫苗及其制备方法 |
| US9567606B2 (en) | 2012-02-14 | 2017-02-14 | Merial Inc. | Recombinant poxviral vectors expressing both rabies and OX40 proteins, and vaccines made therefrom |
-
2013
- 2013-02-14 US US13/767,603 patent/US9567606B2/en active Active
- 2013-02-14 EP EP13707085.0A patent/EP2814506B1/en not_active Not-in-force
- 2013-02-14 AU AU2013221502A patent/AU2013221502C1/en not_active Ceased
- 2013-02-14 MX MX2014009845A patent/MX360415B/es active IP Right Grant
- 2013-02-14 WO PCT/US2013/026206 patent/WO2013123242A1/en not_active Ceased
- 2013-02-14 EP EP18208513.4A patent/EP3466443B1/en not_active Not-in-force
- 2013-02-14 CA CA2864119A patent/CA2864119C/en active Active
- 2013-02-14 CN CN201380015514.8A patent/CN104203271B/zh not_active Expired - Fee Related
- 2013-02-14 JP JP2014557782A patent/JP6260972B2/ja not_active Expired - Fee Related
- 2013-02-14 NZ NZ722700A patent/NZ722700A/en not_active IP Right Cessation
- 2013-02-14 BR BR112014020019A patent/BR112014020019A8/pt active Search and Examination
- 2013-02-14 NZ NZ628270A patent/NZ628270A/en not_active IP Right Cessation
- 2013-02-14 ES ES13707085T patent/ES2723273T3/es active Active
- 2013-02-14 EA EA201400912A patent/EA032389B1/ru not_active IP Right Cessation
- 2013-02-14 ES ES18208513T patent/ES2866108T3/es active Active
-
2017
- 2017-01-19 US US15/410,588 patent/US10006050B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2015511948A5 (enExample) | ||
| ES2540858T3 (es) | Composición farmacéutica para el tratamiento y/o la prevención de cáncer | |
| BR112018012962A2 (pt) | vacinas de zika recombinantes | |
| ES2662801T3 (es) | Vacunas atenuadas contra Streptoccocus suis y procedimientos de fabricación y uso de las mismas | |
| JP2018520997A5 (enExample) | ||
| EA201400912A1 (ru) | Рекомбинантные поксвирусные векторы, экспрессирующие белки вируса бешенства и ox40, и вакцины, созданные на их основе | |
| BR112016019068A2 (pt) | construto, vetor recombinante, composição farmacêutica, método de inibição de replicação viral ou expressão de uma sequência alvo em uma célula infectada com um vírus, polipeptídeo de sau cas9 recombinante, construto de sau cas9 recombinante, construto recombinante para expressão de um rna guia individual e kit | |
| AR089039A1 (es) | Vectores recombinantes de hvt que expresan antigenos de patogenos de aves y sus usos | |
| AR096920A1 (es) | Quimeras de pululanasa y polinucleótidos que las codifican | |
| MX348464B (es) | Agente inductor de inmunidad. | |
| CL2011000947A1 (es) | Polipeptido lectina; molecula de acido nucleico que la codifica; vector y celula hospedera; metodo para preparar el polipeptido; composicion farmaceutica que comprende el polipeptido; uso del polipeptido para preparar un medicamento para tratar transtorno autoinmune, inflamatorio o de piel dañada de un animal. | |
| RU2017116973A (ru) | Способы применения и композиции нейрегулинов для предотвращения, лечения или замедления сердечной недостаточности с сохраненной фракцией выброса | |
| PE20150356A1 (es) | Composiciones de vacuna para la prevencion contra la infeccion por el virus del dengue | |
| TR201909342T4 (tr) | Rekombi̇nant marek hastaliği vi̇rüsleri̇ ve bunlarin kullanimlari | |
| UA110328C2 (en) | Recombinant vaccine based on avian paramixoviruses and method for its preparation and administration | |
| MX2017010908A (es) | Vacuna bivalente contra el virus de gripe porcina. | |
| EA202190267A1 (ru) | Способы и композиции с использованием рекомбинантных дендритных клеток для терапии рака | |
| CL2022002416A1 (es) | Vacuna | |
| JP2017039729A5 (enExample) | ||
| NZ712713A (en) | Attenuated swine influenza vaccines and methods of making and use thereof | |
| JP2012506699A5 (enExample) | ||
| CO2017011431A2 (es) | Proteínas de fusión de receptor de factor de crecimiento epidermal variante iii - mesotelina | |
| RU2017126212A (ru) | Композиция | |
| EA201890274A1 (ru) | Векторная система из аденовируса 9 птиц (fadv-9) и связанные способы | |
| RU2012149036A (ru) | Векторы парапоксвируса, содержащие антиген вируса бешенства |