MX360415B - Vectores poxvirales recombinantes que expresan proteinas tanto de rabia como de ox40, y vacunas hechas a partir de los mismos. - Google Patents
Vectores poxvirales recombinantes que expresan proteinas tanto de rabia como de ox40, y vacunas hechas a partir de los mismos.Info
- Publication number
- MX360415B MX360415B MX2014009845A MX2014009845A MX360415B MX 360415 B MX360415 B MX 360415B MX 2014009845 A MX2014009845 A MX 2014009845A MX 2014009845 A MX2014009845 A MX 2014009845A MX 360415 B MX360415 B MX 360415B
- Authority
- MX
- Mexico
- Prior art keywords
- rabies
- proteins
- polypeptide
- made therefrom
- vectors expressing
- Prior art date
Links
- 239000013598 vector Substances 0.000 title abstract 4
- 206010037742 Rabies Diseases 0.000 title abstract 2
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 229960005486 vaccine Drugs 0.000 title 1
- 230000002163 immunogen Effects 0.000 abstract 4
- 229920001184 polypeptide Polymers 0.000 abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 4
- 102000004473 OX40 Ligand Human genes 0.000 abstract 3
- 108010042215 OX40 Ligand Proteins 0.000 abstract 3
- 230000028993 immune response Effects 0.000 abstract 3
- 241000282465 Canis Species 0.000 abstract 2
- 239000002671 adjuvant Substances 0.000 abstract 2
- 230000002068 genetic effect Effects 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 1
- 241000711798 Rabies lyssavirus Species 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/002—Protozoa antigens
- A61K39/008—Leishmania antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/205—Rhabdoviridae, e.g. rabies virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
- C12N15/863—Poxviral vectors, e.g. entomopoxvirus
- C12N15/8633—Avian poxviral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24041—Use of virus, viral particle or viral elements as a vector
- C12N2710/24043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20111—Lyssavirus, e.g. rabies virus
- C12N2760/20134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261598610P | 2012-02-14 | 2012-02-14 | |
| PCT/US2013/026206 WO2013123242A1 (en) | 2012-02-14 | 2013-02-14 | Recombinant poxviral vectors expressing both rabies and ox40 proteins, and vaccines made therefrom |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2014009845A MX2014009845A (es) | 2015-03-10 |
| MX360415B true MX360415B (es) | 2018-10-31 |
Family
ID=47757705
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014009845A MX360415B (es) | 2012-02-14 | 2013-02-14 | Vectores poxvirales recombinantes que expresan proteinas tanto de rabia como de ox40, y vacunas hechas a partir de los mismos. |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US9567606B2 (enExample) |
| EP (2) | EP2814506B1 (enExample) |
| JP (1) | JP6260972B2 (enExample) |
| CN (1) | CN104203271B (enExample) |
| AU (1) | AU2013221502C1 (enExample) |
| BR (1) | BR112014020019A8 (enExample) |
| CA (1) | CA2864119C (enExample) |
| EA (1) | EA032389B1 (enExample) |
| ES (2) | ES2723273T3 (enExample) |
| MX (1) | MX360415B (enExample) |
| NZ (2) | NZ722700A (enExample) |
| WO (1) | WO2013123242A1 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009111738A2 (en) | 2008-03-06 | 2009-09-11 | Mayo Foundation For Medical Education And Research | Single cycle replicating adenovirus vectors |
| US9567606B2 (en) | 2012-02-14 | 2017-02-14 | Merial Inc. | Recombinant poxviral vectors expressing both rabies and OX40 proteins, and vaccines made therefrom |
| US9974845B2 (en) | 2013-02-22 | 2018-05-22 | Curevac Ag | Combination of vaccination and inhibition of the PD-1 pathway |
| US10196435B2 (en) * | 2013-11-18 | 2019-02-05 | University Of Southern California | OX40L fusion protein for the immunotherapy of tumors of veterinary animals |
| MX375528B (es) | 2013-12-20 | 2025-03-06 | Boehringer Ingelheim Vetmedica Gmbh | Variante del virus prrs, clon de adnc del virus europeo y sus usos. |
| CN103877570B (zh) * | 2014-02-19 | 2016-01-20 | 北京中联康生物科技有限公司 | 狂犬病活疫苗和制备狂犬病口服活疫苗的方法 |
| ES2754239T3 (es) | 2014-03-12 | 2020-04-16 | Curevac Ag | Combinación de vacunación y agonistas de OX40 |
| US10010499B2 (en) | 2014-11-03 | 2018-07-03 | Merial Inc. | Methods of using microneedle vaccine formulations to elicit in animals protective immunity against rabies virus |
| SG11201705844SA (en) | 2015-02-06 | 2017-08-30 | Heat Biologics Inc | Vector co-expressing vaccine and costimulatory molecules |
| DK3458474T3 (da) | 2016-05-18 | 2022-09-26 | Modernatx Inc | Kombinationer af mrna'er, der koder for immunmodulerende polypeptider og anvendelser deraf |
| US11666649B2 (en) | 2016-10-11 | 2023-06-06 | University Of Miami | Vectors and vaccine cells for immunity against Zika virus |
| CA3058938A1 (en) | 2017-04-04 | 2018-10-11 | Heat Biologics, Inc. | Intratumoral vaccination |
| CA3088646A1 (en) | 2018-02-23 | 2019-08-29 | Boehringer Ingelheim Vetmedica Gmbh | Recombinant viral vector systems expressing exogenous feline paramyxovirus genes and vaccines made therefrom |
| US12042527B2 (en) | 2019-01-08 | 2024-07-23 | Modernatx, Inc. | Use of mRNAs encoding OX40L, IL-23 and IL-36gamma in combination with immune checkpoint blockade for treating particular cancers |
| CN111518776A (zh) * | 2020-04-16 | 2020-08-11 | 大理大学 | 一种重组狂犬病病毒疫苗株及其制备方法 |
| GB202012331D0 (en) * | 2020-08-07 | 2020-09-23 | Petmedix Ltd | Therapeutic antibodies |
| US11149286B1 (en) * | 2020-08-17 | 2021-10-19 | Mayo Foundation For Medical Education And Research | Adenovirus vectors and methods for using adenovirus vectors |
| EP4476256A1 (en) * | 2022-02-09 | 2024-12-18 | Petmedix Ltd. | Therapeutic antibodies |
| CN116656730B (zh) * | 2023-05-25 | 2024-03-19 | 军事科学院军事医学研究院军事兽医研究所 | 一种表达狂犬病病毒g、m蛋白的重组金丝雀痘病毒及其构建方法 |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US2909462A (en) | 1955-12-08 | 1959-10-20 | Bristol Myers Co | Acrylic acid polymer laxative compositions |
| US5505941A (en) | 1981-12-24 | 1996-04-09 | Health Research, Inc. | Recombinant avipox virus and method to induce an immune response |
| US4708871A (en) | 1983-03-08 | 1987-11-24 | Commonwealth Serum Laboratories Commission | Antigenically active amino acid sequences |
| DE3584341D1 (de) | 1984-08-24 | 1991-11-14 | Upjohn Co | Rekombinante dna-verbindungen und expression von polypeptiden wie tpa. |
| AU672359B2 (en) * | 1991-03-07 | 1996-10-03 | Virogenetics Corporation | Genetically engineered vaccine strain |
| US6309647B1 (en) | 1999-07-15 | 2001-10-30 | Aventis Pasteur | Poxvirus—canine dispemper virus (CDV) or measles virus recombinants and compositions and methods employing the recombinants |
| US5756102A (en) | 1990-11-20 | 1998-05-26 | Virogenetics Corporation | Poxvirus-canine distemper virus (CDV) recombinants and compositions and methods employing the recombinants |
| US5843456A (en) | 1991-03-07 | 1998-12-01 | Virogenetics Corporation | Alvac poxvirus-rabies compositions and combination compositions and uses |
| FR2724385B1 (fr) | 1994-08-29 | 1996-12-13 | Rhone Merieux | Vaccin de la peritonite infectieuse feline. |
| EP0826063A1 (en) | 1995-04-25 | 1998-03-04 | Vical Incorporated | Single-vial formulations of dna/lipid complexes |
| US5846946A (en) | 1996-06-14 | 1998-12-08 | Pasteur Merieux Serums Et Vaccins | Compositions and methods for administering Borrelia DNA |
| FR2751227B1 (fr) | 1996-07-19 | 1998-11-27 | Rhone Merieux | Formule de vaccin polynucleotidique contre les pathologies canines, notamment les pathologies respiratoires et digestives |
| FR2751224B1 (fr) | 1996-07-19 | 1998-11-20 | Rhone Merieux | Formule de vaccin polynucleotidique contre les pathologies respiratoires et de reproduction des porcs |
| FR2751226B1 (fr) | 1996-07-19 | 1998-11-27 | Rhone Merieux | Formule de vaccin polynucleotidique contre les pathologies du cheval |
| FR2751225B1 (fr) | 1996-07-19 | 1998-11-27 | Rhone Merieux | Formule de vaccin polynucleotidique aviaire |
| FR2751229B1 (fr) | 1996-07-19 | 1998-11-27 | Rhone Merieux | Formule de vaccin polynucleotidique notamment contre la pathologie respiratoire des bovins |
| FR2751228B1 (fr) | 1996-07-19 | 1998-11-20 | Rhone Merieux | Vaccin polynucleotidique bovin pour voie intradermique |
| CA2294793A1 (fr) | 1997-06-30 | 1999-01-14 | Rhone-Poulenc Rorer S.A. | Amelioration du transfert d'acide nucleique dans le muscle strie et combinaison permettant la mise en oeuvre du procede |
| FR2775601B1 (fr) | 1998-03-03 | 2001-09-21 | Merial Sas | Vaccins vivants recombines et adjuves |
| US6497883B1 (en) | 1999-06-10 | 2002-12-24 | Merial | Porcine circovirus recombinant poxvirus vaccine |
| US6541458B1 (en) | 1999-07-16 | 2003-04-01 | Merial | Feline calicivirus genes and vaccines in particular recombinant vaccines |
| US6852705B2 (en) | 2000-01-21 | 2005-02-08 | Merial | DNA vaccines for farm animals, in particular bovines and porcines |
| JP2004517057A (ja) * | 2000-11-03 | 2004-06-10 | オックスフォード バイオメディカ（ユーケイ）リミテッド | ベクターシステム |
| US7740863B2 (en) | 2001-04-06 | 2010-06-22 | Merial | Recombinant vaccine against West Nile Virus |
| US7582302B2 (en) | 2004-06-04 | 2009-09-01 | Merial Limited | Needle-free administration of FeLV vaccines |
| DK1773387T3 (da) | 2004-06-25 | 2013-07-15 | Merial Ltd | Avipox-rekombinanter der udtrykker mund- og klovesyge-virusgener |
| US8980280B2 (en) | 2005-03-30 | 2015-03-17 | Merial, Inc. | Recombinant feline leukemia virus vaccine containing optimized feline leukemia virus envelope gene |
| SI1881845T1 (sl) | 2005-04-25 | 2010-06-30 | Merial Ltd | Cepiva proti virusu Nipah |
| US7384642B2 (en) | 2005-08-25 | 2008-06-10 | Merial Limited | Canine influenza vaccines |
| US7862821B2 (en) | 2006-06-01 | 2011-01-04 | Merial Limited | Recombinant vaccine against bluetongue virus |
| US8008268B2 (en) | 2006-07-25 | 2011-08-30 | Merial Limited | Vaccines against vesicular stomatitis |
| US7910112B2 (en) | 2006-11-06 | 2011-03-22 | Merial Limited | Feline vaccines against avian influenza |
| CA2670097C (en) | 2006-11-21 | 2015-10-06 | Merial Limited | Prime boost canine leishmania vaccine |
| BRPI0920622B1 (pt) | 2008-10-24 | 2019-11-12 | Merial, Inc. | vacina contra o vírus da doença equina africana |
| CN101884793A (zh) * | 2010-06-29 | 2010-11-17 | 中国人民解放军第三军医大学 | 乙肝病毒核心抗原的免疫增强型基因疫苗及其制备方法 |
| US9567606B2 (en) | 2012-02-14 | 2017-02-14 | Merial Inc. | Recombinant poxviral vectors expressing both rabies and OX40 proteins, and vaccines made therefrom |
-
2013
- 2013-02-14 US US13/767,603 patent/US9567606B2/en active Active
- 2013-02-14 EP EP13707085.0A patent/EP2814506B1/en not_active Not-in-force
- 2013-02-14 AU AU2013221502A patent/AU2013221502C1/en not_active Ceased
- 2013-02-14 MX MX2014009845A patent/MX360415B/es active IP Right Grant
- 2013-02-14 WO PCT/US2013/026206 patent/WO2013123242A1/en not_active Ceased
- 2013-02-14 EP EP18208513.4A patent/EP3466443B1/en not_active Not-in-force
- 2013-02-14 CA CA2864119A patent/CA2864119C/en active Active
- 2013-02-14 CN CN201380015514.8A patent/CN104203271B/zh not_active Expired - Fee Related
- 2013-02-14 JP JP2014557782A patent/JP6260972B2/ja not_active Expired - Fee Related
- 2013-02-14 NZ NZ722700A patent/NZ722700A/en not_active IP Right Cessation
- 2013-02-14 BR BR112014020019A patent/BR112014020019A8/pt active Search and Examination
- 2013-02-14 NZ NZ628270A patent/NZ628270A/en not_active IP Right Cessation
- 2013-02-14 ES ES13707085T patent/ES2723273T3/es active Active
- 2013-02-14 EA EA201400912A patent/EA032389B1/ru not_active IP Right Cessation
- 2013-02-14 ES ES18208513T patent/ES2866108T3/es active Active
-
2017
- 2017-01-19 US US15/410,588 patent/US10006050B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EA201400912A1 (ru) | 2015-01-30 |
| AU2013221502B2 (en) | 2017-10-26 |
| ES2723273T3 (es) | 2019-08-23 |
| US10006050B2 (en) | 2018-06-26 |
| AU2013221502C1 (en) | 2018-03-01 |
| BR112014020019A8 (pt) | 2022-07-12 |
| CA2864119C (en) | 2022-05-24 |
| ES2866108T3 (es) | 2021-10-19 |
| EP3466443A1 (en) | 2019-04-10 |
| AU2013221502A1 (en) | 2014-08-28 |
| EP2814506B1 (en) | 2018-11-28 |
| NZ628270A (en) | 2016-09-30 |
| CN104203271A (zh) | 2014-12-10 |
| CA2864119A1 (en) | 2013-08-22 |
| US20170137843A1 (en) | 2017-05-18 |
| NZ722700A (en) | 2017-12-22 |
| EP2814506A1 (en) | 2014-12-24 |
| EA032389B1 (ru) | 2019-05-31 |
| EP3466443B1 (en) | 2020-12-16 |
| US20130209511A1 (en) | 2013-08-15 |
| US9567606B2 (en) | 2017-02-14 |
| JP6260972B2 (ja) | 2018-01-17 |
| JP2015511948A (ja) | 2015-04-23 |
| BR112014020019A2 (pt) | 2017-07-04 |
| WO2013123242A1 (en) | 2013-08-22 |
| CN104203271B (zh) | 2017-08-25 |
| MX2014009845A (es) | 2015-03-10 |
| HK1200327A1 (en) | 2015-08-07 |
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