MX352974B - Moleculas de acido nucleico que codifican novedosos antigenos de herpes, vacunas que las comprenden y metodos para su uso. - Google Patents

Moleculas de acido nucleico que codifican novedosos antigenos de herpes, vacunas que las comprenden y metodos para su uso.

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Publication number
MX352974B
MX352974B MX2013008836A MX2013008836A MX352974B MX 352974 B MX352974 B MX 352974B MX 2013008836 A MX2013008836 A MX 2013008836A MX 2013008836 A MX2013008836 A MX 2013008836A MX 352974 B MX352974 B MX 352974B
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Mexico
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methods
nucleic acid
vaccine
same
acid molecules
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MX2013008836A
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MX2013008836A (es
Inventor
B Weiner David
J Shedlock Devon
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Univ Pennsylvania
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Publication of MX2013008836A publication Critical patent/MX2013008836A/es
Publication of MX352974B publication Critical patent/MX352974B/es

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    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/245Herpetoviridae, e.g. herpes simplex virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/245Herpetoviridae, e.g. herpes simplex virus
    • A61K39/25Varicella-zoster virus
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
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    • C12N2710/16011Herpesviridae
    • C12N2710/16111Cytomegalovirus, e.g. human herpesvirus 5
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    • C12N2710/16611Simplexvirus, e.g. human herpesvirus 1, 2
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    • C12N2710/16011Herpesviridae
    • C12N2710/16611Simplexvirus, e.g. human herpesvirus 1, 2
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    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16711Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
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    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16711Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16734Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Health & Medical Sciences (AREA)
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Abstract

La presente invención se refiere a secuencias de ácidos nucleicos que codifican nuevas secuencias de aminoácidos consenso de antígenos del virus del herpes, así como construcciones/vectores genéticos y vacunas que expresan las secuencias. En la presente también se proporcionan métodos para generar una respuesta inmunitaria contra el virus del herpes utilizando las vacunas que se proporcionan.
MX2013008836A 2011-01-31 2012-01-31 Moleculas de acido nucleico que codifican novedosos antigenos de herpes, vacunas que las comprenden y metodos para su uso. MX352974B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161438089P 2011-01-31 2011-01-31
PCT/US2012/023398 WO2012106377A2 (en) 2011-01-31 2012-01-31 Nucleic acid molecules encoding novel herpes antigens, vaccine comprising the same, and methods of use thereof

Publications (2)

Publication Number Publication Date
MX2013008836A MX2013008836A (es) 2013-12-06
MX352974B true MX352974B (es) 2017-12-15

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MX2013008836A MX352974B (es) 2011-01-31 2012-01-31 Moleculas de acido nucleico que codifican novedosos antigenos de herpes, vacunas que las comprenden y metodos para su uso.

Country Status (12)

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US (2) US9243041B2 (es)
EP (1) EP2670443A4 (es)
JP (3) JP6099573B2 (es)
KR (1) KR20140007404A (es)
CN (2) CN103827131B (es)
AU (2) AU2012212264B2 (es)
BR (1) BR112013020070A8 (es)
CA (1) CA2826199A1 (es)
EA (1) EA033467B1 (es)
HK (1) HK1198538A1 (es)
MX (1) MX352974B (es)
WO (1) WO2012106377A2 (es)

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