HK1198538A1 - Nucleic acid molecules encoding novel herpes antigens, vaccine comprising the same, and methods of use thereof - Google Patents
Nucleic acid molecules encoding novel herpes antigens, vaccine comprising the same, and methods of use thereofInfo
- Publication number
- HK1198538A1 HK1198538A1 HK14112004.3A HK14112004A HK1198538A1 HK 1198538 A1 HK1198538 A1 HK 1198538A1 HK 14112004 A HK14112004 A HK 14112004A HK 1198538 A1 HK1198538 A1 HK 1198538A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- vaccine
- methods
- nucleic acid
- same
- acid molecules
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/245—Herpetoviridae, e.g. herpes simplex virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/245—Herpetoviridae, e.g. herpes simplex virus
- A61K39/25—Varicella-zoster virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16111—Cytomegalovirus, e.g. human herpesvirus 5
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16111—Cytomegalovirus, e.g. human herpesvirus 5
- C12N2710/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16111—Cytomegalovirus, e.g. human herpesvirus 5
- C12N2710/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16622—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
- C12N2710/16722—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
- C12N2710/16734—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161438089P | 2011-01-31 | 2011-01-31 | |
PCT/US2012/023398 WO2012106377A2 (en) | 2011-01-31 | 2012-01-31 | Nucleic acid molecules encoding novel herpes antigens, vaccine comprising the same, and methods of use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1198538A1 true HK1198538A1 (en) | 2015-05-15 |
Family
ID=46603275
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK14112004.3A HK1198538A1 (en) | 2011-01-31 | 2014-11-27 | Nucleic acid molecules encoding novel herpes antigens, vaccine comprising the same, and methods of use thereof |
Country Status (12)
Country | Link |
---|---|
US (2) | US9243041B2 (xx) |
EP (1) | EP2670443A4 (xx) |
JP (3) | JP6099573B2 (xx) |
KR (1) | KR20140007404A (xx) |
CN (2) | CN103827131B (xx) |
AU (2) | AU2012212264B2 (xx) |
BR (1) | BR112013020070A8 (xx) |
CA (1) | CA2826199A1 (xx) |
EA (1) | EA033467B1 (xx) |
HK (1) | HK1198538A1 (xx) |
MX (1) | MX352974B (xx) |
WO (1) | WO2012106377A2 (xx) |
Families Citing this family (44)
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PL2590626T3 (pl) | 2010-07-06 | 2016-04-29 | Glaxosmithkline Biologicals Sa | Liposomy z lipidami o korzystnej wartości pka do dostarczania rna |
LT3981427T (lt) | 2010-08-31 | 2022-08-10 | Glaxosmithkline Biologicals S.A. | Pegilintos liposomos, skirtos imunogeną koduojančios rnr pristatymui |
MX363307B (es) * | 2010-10-11 | 2019-03-20 | Novartis Ag Star | Plataformas para suministro de antigenos. |
CA2840989A1 (en) | 2011-07-06 | 2013-01-10 | Novartis Ag | Immunogenic combination compositions and uses thereof |
SG11201408328VA (en) * | 2012-07-06 | 2015-02-27 | Novartis Ag | Complexes of cytomegalovirus proteins |
CN104838000B (zh) * | 2012-07-27 | 2022-12-20 | 希望之城 | 一种递送ul128复合体和预防cmv感染的mva疫苗 |
SG10201701828WA (en) * | 2012-09-07 | 2017-04-27 | Agency Science Tech & Res | Peptides and their uses |
KR20210088741A (ko) * | 2012-12-13 | 2021-07-14 | 더 트러스티스 오브 더 유니버시티 오브 펜실베니아 | Dna 항체 작제물 및 그 이용 방법 |
US10220082B2 (en) | 2012-12-13 | 2019-03-05 | Inovio Pharmaceuticals, Inc. | WT1 vaccine |
CN105209066A (zh) * | 2013-03-15 | 2015-12-30 | 宾夕法尼亚大学理事会 | 使用来自肉毒梭菌的血清型的重链的基于单价或多价肉毒杆菌神经毒素的疫苗 |
WO2015048744A2 (en) | 2013-09-30 | 2015-04-02 | Moderna Therapeutics, Inc. | Polynucleotides encoding immune modulating polypeptides |
WO2015161926A1 (en) * | 2014-04-23 | 2015-10-29 | Institute For Research In Biomedicine | Human cytomegalovirus vaccine compositions and method of producing the same |
WO2015165480A1 (en) * | 2014-04-30 | 2015-11-05 | Institute For Research In Biomedicine | Human cytomegalovirus vaccine compositions and method of producing the same |
WO2015168650A2 (en) * | 2014-05-02 | 2015-11-05 | University Of Washington | Epitopes cross-reactive between hsv-1, hsv-2 and vzv and methods for using same |
MX2016014660A (es) * | 2014-05-08 | 2017-02-28 | Pfizer | Medios y metodos para el tratamiento de cmv. |
WO2016036503A1 (en) * | 2014-09-04 | 2016-03-10 | Arizona Board Of Regents On Behalf Of Arizona State University | Antigen compositions and methods of use for treating extraintestinal pathogenic e. coli infections |
KR101723605B1 (ko) * | 2014-10-21 | 2017-04-07 | 진원생명과학 주식회사 | 대상포진 예방 및 치료용 dna 백신 조성물 및 이를 이용한 vzv 항원에 대한 t세포 활성화 방법 |
CA2969214A1 (en) | 2014-12-01 | 2016-06-09 | The Trustees Of The University Of Pennsylvania | Dna antibody constructs and method of using same |
CN105669838B (zh) * | 2014-12-04 | 2020-10-16 | 厦门大学 | 来自水痘-带状疱疹病毒gE蛋白的中和表位及针对其的抗体 |
US20180303929A1 (en) * | 2015-10-22 | 2018-10-25 | Moderna TX, Inc. | Herpes simplex virus vaccine |
EP3364981A4 (en) | 2015-10-22 | 2019-08-07 | ModernaTX, Inc. | VACCINE AGAINST THE HUMAN CYTOMEGALOVIRUS |
CA3002912A1 (en) * | 2015-10-22 | 2017-04-27 | Modernatx, Inc. | Nucleic acid vaccines for varicella zoster virus (vzv) |
CA3015792A1 (en) * | 2016-02-25 | 2017-08-31 | The Trustees Of The University Of Pennsylvania | Novel vaccines against zika virus |
JP6980780B2 (ja) | 2016-10-21 | 2021-12-15 | モデルナティーエックス, インコーポレイテッド | ヒトサイトメガロウイルスワクチン |
RU2736472C2 (ru) * | 2016-11-18 | 2020-11-17 | Общество с ограниченной ответственностью "ЭКСИФАРМ" | Химерный белок, синтетическая днк, кодирующая указанный белок, экспрессионный вектор, штамм-продуцент синтетической днк и способ получения плазмидной днк |
CA3050914A1 (en) * | 2017-01-27 | 2018-08-02 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. | Vaccine compositions of herpesvirus envelope protein combinations to induce immune response |
US11752206B2 (en) | 2017-03-15 | 2023-09-12 | Modernatx, Inc. | Herpes simplex virus vaccine |
US11045540B2 (en) | 2017-03-15 | 2021-06-29 | Modernatx, Inc. | Varicella zoster virus (VZV) vaccine |
CN108727503A (zh) * | 2017-04-18 | 2018-11-02 | 武汉博沃生物科技有限公司 | VZV重组gE-鞭毛素融合蛋白及其制备方法和应用 |
US20200054737A1 (en) * | 2017-04-26 | 2020-02-20 | Modema TX, Inc. | Herpes simplex virus vaccine |
EP3677592A4 (en) * | 2017-08-30 | 2021-06-09 | KM Biologics Co., Ltd. | MODIFIED HSV GD PROTEIN AND VACCINE CONTAINING IT |
CN108315344A (zh) * | 2018-02-14 | 2018-07-24 | 武汉博沃生物科技有限公司 | Vzv糖蛋白e基因表达载体及其重组酵母菌株与应用 |
WO2019161163A1 (en) * | 2018-02-16 | 2019-08-22 | The Wistar Institute Of Anatomy And Biology | Epstein-barr virus nucleic acid constructs and vaccines made therefrom, and methods of using same |
WO2019225962A1 (ko) * | 2018-05-23 | 2019-11-28 | 재단법인 목암생명과학연구소 | 바리셀라 조스터 바이러스의 항원 변이체 및 이의 용도 |
EP3868399A4 (en) * | 2018-09-27 | 2022-07-20 | Bravovax Co., Ltd. | IMMUNE COMPOSITION, METHOD FOR PREPARATION AND ASSOCIATED APPLICATION |
US11629172B2 (en) | 2018-12-21 | 2023-04-18 | Pfizer Inc. | Human cytomegalovirus gB polypeptide |
CN109602901B (zh) * | 2019-01-08 | 2022-05-27 | 成都迈科康生物科技有限公司 | 一种带状疱疹病毒疫苗及其制备方法和应用 |
CN112870344B (zh) * | 2019-11-29 | 2022-07-19 | 北京绿竹生物技术股份有限公司 | 一种重组水痘带状疱疹病毒疫苗 |
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TWI810589B (zh) | 2020-06-21 | 2023-08-01 | 美商輝瑞股份有限公司 | 人巨細胞病毒糖蛋白B(gB)多肽 |
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WO2022216895A1 (en) * | 2021-04-09 | 2022-10-13 | University Of Florida Research Foundation, Incorporated | Methods, kits, and approaches for viral vaccines |
CN114163503B (zh) * | 2021-12-15 | 2023-11-24 | 北京交通大学 | 两种表达水痘-带状疱疹病毒的gE蛋白的重组腺病毒及应用 |
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2012
- 2012-01-31 KR KR20137022593A patent/KR20140007404A/ko not_active Application Discontinuation
- 2012-01-31 EP EP12742746.6A patent/EP2670443A4/en not_active Ceased
- 2012-01-31 MX MX2013008836A patent/MX352974B/es active IP Right Grant
- 2012-01-31 CN CN201280012809.5A patent/CN103827131B/zh not_active Expired - Fee Related
- 2012-01-31 JP JP2013551433A patent/JP6099573B2/ja not_active Expired - Fee Related
- 2012-01-31 CN CN201710423291.9A patent/CN107090463A/zh active Pending
- 2012-01-31 US US13/982,457 patent/US9243041B2/en active Active
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- 2012-01-31 AU AU2012212264A patent/AU2012212264B2/en not_active Ceased
- 2012-01-31 EA EA201391109A patent/EA033467B1/ru not_active IP Right Cessation
- 2012-01-31 CA CA 2826199 patent/CA2826199A1/en not_active Abandoned
- 2012-01-31 WO PCT/US2012/023398 patent/WO2012106377A2/en active Application Filing
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Also Published As
Publication number | Publication date |
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WO2012106377A2 (en) | 2012-08-09 |
JP2014513522A (ja) | 2014-06-05 |
MX2013008836A (es) | 2013-12-06 |
US20140023673A1 (en) | 2014-01-23 |
CN103827131A (zh) | 2014-05-28 |
KR20140007404A (ko) | 2014-01-17 |
EA033467B1 (ru) | 2019-10-31 |
WO2012106377A3 (en) | 2014-03-06 |
US9243041B2 (en) | 2016-01-26 |
BR112013020070A2 (pt) | 2018-03-06 |
EP2670443A2 (en) | 2013-12-11 |
CA2826199A1 (en) | 2012-08-09 |
US20160130308A1 (en) | 2016-05-12 |
MX352974B (es) | 2017-12-15 |
AU2012212264A1 (en) | 2013-08-15 |
US9994619B2 (en) | 2018-06-12 |
CN103827131B (zh) | 2017-06-30 |
JP2019010120A (ja) | 2019-01-24 |
JP6099573B2 (ja) | 2017-03-22 |
AU2012212264B2 (en) | 2016-01-28 |
JP2017035112A (ja) | 2017-02-16 |
AU2016202122B2 (en) | 2018-03-29 |
CN107090463A (zh) | 2017-08-25 |
EA201391109A1 (ru) | 2014-03-31 |
AU2016202122A1 (en) | 2016-04-28 |
EP2670443A4 (en) | 2015-10-14 |
BR112013020070A8 (pt) | 2019-09-03 |
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