EA201890274A1 - Векторная система из аденовируса 9 птиц (fadv-9) и связанные способы - Google Patents

Векторная система из аденовируса 9 птиц (fadv-9) и связанные способы

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Publication number
EA201890274A1
EA201890274A1 EA201890274A EA201890274A EA201890274A1 EA 201890274 A1 EA201890274 A1 EA 201890274A1 EA 201890274 A EA201890274 A EA 201890274A EA 201890274 A EA201890274 A EA 201890274A EA 201890274 A1 EA201890274 A1 EA 201890274A1
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EA
Eurasian Patent Office
Prior art keywords
fadv
vectors
adenovirus
birds
related methods
Prior art date
Application number
EA201890274A
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English (en)
Inventor
Яньлун Пэй
Джеймс Экфорд
Хуан Карлос Корредор
Питер Дж. Крелл
Эва Нажи
Original Assignee
Юниверсити Оф Гуэлф
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Юниверсити Оф Гуэлф filed Critical Юниверсити Оф Гуэлф
Publication of EA201890274A1 publication Critical patent/EA201890274A1/ru

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C12N15/861—Adenoviral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10211—Aviadenovirus, e.g. fowl adenovirus A
    • C12N2710/10241—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10243—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/48—Vector systems having a special element relevant for transcription regulating transport or export of RNA, e.g. RRE, PRE, WPRE, CTE

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Описаны рекомбинантные вирусные векторы, полученные из аденовируса 9 птиц (FAdV-9), и связанные способы. Рекомбинантные FAdV-9 векторы могут содержать одну или несколько делеций на левом конце и/или правом конце генома FAdV-9. Необязательно векторы содержат одну или несколько экзогенных нуклеотидных последовательностей, такие последовательности кодируют полипептид, представляющий интерес. Рекомбинантные FAdV-9 векторы можно использовать в качестве вектора для двойной доставки. Также описано применение векторов для создания иммуногенного ответа у пациента и/или для профилактики заболевания.
EA201890274A 2015-07-10 2016-07-11 Векторная система из аденовируса 9 птиц (fadv-9) и связанные способы EA201890274A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562190913P 2015-07-10 2015-07-10
PCT/CA2016/050811 WO2017008154A1 (en) 2015-07-10 2016-07-11 Fowl adenovirus 9 (fadv-9) vector system and associated methods

Publications (1)

Publication Number Publication Date
EA201890274A1 true EA201890274A1 (ru) 2018-08-31

Family

ID=57756612

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201890274A EA201890274A1 (ru) 2015-07-10 2016-07-11 Векторная система из аденовируса 9 птиц (fadv-9) и связанные способы

Country Status (11)

Country Link
US (2) US20190153470A1 (ru)
EP (1) EP3320100A4 (ru)
BR (1) BR112018000194A2 (ru)
CA (1) CA2991925A1 (ru)
CO (1) CO2018001339A2 (ru)
EA (1) EA201890274A1 (ru)
IL (1) IL256801B (ru)
MX (1) MX2018000353A (ru)
PE (1) PE20181087A1 (ru)
WO (1) WO2017008154A1 (ru)
ZA (1) ZA201800705B (ru)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016020730A1 (es) * 2014-08-08 2016-02-11 Laboratorio Avi-Mex, S.A. De C.V. Vacuna en vector recombinante de adenovirus aviar serotipo 9
CA3173714A1 (en) * 2020-03-29 2021-10-07 Uwe D. Staerz Replication-deficient avian adenoviral vectors, their design and uses
CN112094824B (zh) * 2020-08-19 2021-04-20 湖北省农业科学院畜牧兽医研究所 表达禽腺病毒4型截短Fiber2蛋白的重组新城疫病毒耐热疫苗株及其制备方法与应用
CN113584231B (zh) * 2021-09-10 2024-04-19 广西壮族自治区兽医研究所 鉴定i群禽腺病毒血清8型的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6296852B1 (en) * 1993-04-14 2001-10-02 Commonwealth Scientific And Industrial Research Organisation Recombinant avian adenovirus vector
DE19615803A1 (de) * 1996-04-20 1997-10-23 Boehringer Ingelheim Int CELO-Virus
US6841158B1 (en) * 1998-09-22 2005-01-11 Boehringer Ingelheim International Gmbh Recombinant celo virus and celo virus DNA
EP2353610A4 (en) * 2008-11-19 2013-12-11 Avi Mex S A De C V Lab RECOMBINANT INACTIVATED VIRUS VECTOR VACCINE

Also Published As

Publication number Publication date
US20190153470A1 (en) 2019-05-23
PE20181087A1 (es) 2018-07-09
CO2018001339A2 (es) 2018-04-30
IL256801A (en) 2018-03-29
EP3320100A1 (en) 2018-05-16
US20210317476A1 (en) 2021-10-14
WO2017008154A1 (en) 2017-01-19
CA2991925A1 (en) 2017-01-19
EP3320100A4 (en) 2018-12-26
ZA201800705B (en) 2018-12-19
BR112018000194A2 (pt) 2018-09-11
MX2018000353A (es) 2018-03-14
IL256801B (en) 2021-10-31

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