PE20181087A1 - SISTEMA VECTOR DE ADENOVIRUS AVIAR 9 (FAdV-9) Y METODOS ASOCIADOS - Google Patents

SISTEMA VECTOR DE ADENOVIRUS AVIAR 9 (FAdV-9) Y METODOS ASOCIADOS

Info

Publication number
PE20181087A1
PE20181087A1 PE2018000050A PE2018000050A PE20181087A1 PE 20181087 A1 PE20181087 A1 PE 20181087A1 PE 2018000050 A PE2018000050 A PE 2018000050A PE 2018000050 A PE2018000050 A PE 2018000050A PE 20181087 A1 PE20181087 A1 PE 20181087A1
Authority
PE
Peru
Prior art keywords
fadv
avian adenovirus
vector system
adenovirus vector
associated methods
Prior art date
Application number
PE2018000050A
Other languages
English (en)
Inventor
Yanlong Pei
James Ackford
Juan Carlos Corredor
Peter J Krell
Eva Nagy
Original Assignee
Univ Guelph
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Guelph filed Critical Univ Guelph
Publication of PE20181087A1 publication Critical patent/PE20181087A1/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C12N15/861—Adenoviral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10211—Aviadenovirus, e.g. fowl adenovirus A
    • C12N2710/10241—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10243—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/48—Vector systems having a special element relevant for transcription regulating transport or export of RNA, e.g. RRE, PRE, WPRE, CTE

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Referido a vectores virales obtenidos de adenovirus aviar 9 (FAdV-9) recombinantes, que comprende por lo menos una supresion de una region no esencial seleccionada de ORF19 y ORF17. Ademas, pueden incluir una o mas supresiones en regiones no esenciales del genoma de FAdV-9, como: ORF0, ORF1, ORF2, TR2 y ORF11, en el extremo izquierdo y/o extremo derecho. Tambien, comprende una o mas secuencias de nucleotidos exogenos que codifican uno o mas polipeptidos de interes; y es un vector doble que comprende dos secuencias de nucleotidos exogenos que codifican dos polipeptidos de interes. Tambien se refiere a metodos para producir el vector viral; y, su uso para generar una respuesta inmunogenica en un sujeto y/o para prevenir una enfermedad.
PE2018000050A 2015-07-10 2016-07-11 SISTEMA VECTOR DE ADENOVIRUS AVIAR 9 (FAdV-9) Y METODOS ASOCIADOS PE20181087A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562190913P 2015-07-10 2015-07-10

Publications (1)

Publication Number Publication Date
PE20181087A1 true PE20181087A1 (es) 2018-07-09

Family

ID=57756612

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2018000050A PE20181087A1 (es) 2015-07-10 2016-07-11 SISTEMA VECTOR DE ADENOVIRUS AVIAR 9 (FAdV-9) Y METODOS ASOCIADOS

Country Status (11)

Country Link
US (2) US20190153470A1 (es)
EP (1) EP3320100A4 (es)
BR (1) BR112018000194A2 (es)
CA (1) CA2991925A1 (es)
CO (1) CO2018001339A2 (es)
EA (1) EA201890274A1 (es)
IL (1) IL256801B (es)
MX (1) MX2018000353A (es)
PE (1) PE20181087A1 (es)
WO (1) WO2017008154A1 (es)
ZA (1) ZA201800705B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016020730A1 (es) * 2014-08-08 2016-02-11 Laboratorio Avi-Mex, S.A. De C.V. Vacuna en vector recombinante de adenovirus aviar serotipo 9
US20230140994A1 (en) * 2020-03-29 2023-05-11 Greffex, Inc. Replication-deficient avian adenoviral vectors, their design and uses
CN112094824B (zh) * 2020-08-19 2021-04-20 湖北省农业科学院畜牧兽医研究所 表达禽腺病毒4型截短Fiber2蛋白的重组新城疫病毒耐热疫苗株及其制备方法与应用
CN113584231B (zh) * 2021-09-10 2024-04-19 广西壮族自治区兽医研究所 鉴定i群禽腺病毒血清8型的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6296852B1 (en) * 1993-04-14 2001-10-02 Commonwealth Scientific And Industrial Research Organisation Recombinant avian adenovirus vector
DE19615803A1 (de) * 1996-04-20 1997-10-23 Boehringer Ingelheim Int CELO-Virus
US6841158B1 (en) * 1998-09-22 2005-01-11 Boehringer Ingelheim International Gmbh Recombinant celo virus and celo virus DNA
EP2353610A4 (en) * 2008-11-19 2013-12-11 Avi Mex S A De C V Lab RECOMBINANT INACTIVATED VIRUS VECTOR VACCINE

Also Published As

Publication number Publication date
BR112018000194A2 (pt) 2018-09-11
US20210317476A1 (en) 2021-10-14
IL256801B (en) 2021-10-31
EA201890274A1 (ru) 2018-08-31
MX2018000353A (es) 2018-03-14
EP3320100A4 (en) 2018-12-26
ZA201800705B (en) 2018-12-19
EP3320100A1 (en) 2018-05-16
WO2017008154A1 (en) 2017-01-19
CO2018001339A2 (es) 2018-04-30
CA2991925A1 (en) 2017-01-19
IL256801A (en) 2018-03-29
US20190153470A1 (en) 2019-05-23

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