JP2015508104A5 - - Google Patents

Download PDF

Info

Publication number
JP2015508104A5
JP2015508104A5 JP2014558897A JP2014558897A JP2015508104A5 JP 2015508104 A5 JP2015508104 A5 JP 2015508104A5 JP 2014558897 A JP2014558897 A JP 2014558897A JP 2014558897 A JP2014558897 A JP 2014558897A JP 2015508104 A5 JP2015508104 A5 JP 2015508104A5
Authority
JP
Japan
Prior art keywords
composition
therapeutic agent
silk
silk matrix
composition according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2014558897A
Other languages
English (en)
Japanese (ja)
Other versions
JP2015508104A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2013/027465 external-priority patent/WO2013126799A1/en
Publication of JP2015508104A publication Critical patent/JP2015508104A/ja
Publication of JP2015508104A5 publication Critical patent/JP2015508104A5/ja
Pending legal-status Critical Current

Links

JP2014558897A 2012-02-22 2013-02-22 治療薬の眼への送達のための組成物および方法 Pending JP2015508104A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261601924P 2012-02-22 2012-02-22
US61/601,924 2012-02-22
PCT/US2013/027465 WO2013126799A1 (en) 2012-02-22 2013-02-22 Compositions and methods for ocular delivery of a therapeutic agent

Publications (2)

Publication Number Publication Date
JP2015508104A JP2015508104A (ja) 2015-03-16
JP2015508104A5 true JP2015508104A5 (enExample) 2016-04-14

Family

ID=49006267

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014558897A Pending JP2015508104A (ja) 2012-02-22 2013-02-22 治療薬の眼への送達のための組成物および方法

Country Status (6)

Country Link
US (2) US20150037422A1 (enExample)
EP (1) EP2817031A4 (enExample)
JP (1) JP2015508104A (enExample)
CA (1) CA2865132A1 (enExample)
HK (1) HK1205461A1 (enExample)
WO (1) WO2013126799A1 (enExample)

Families Citing this family (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102467714B1 (ko) * 2012-11-08 2022-11-16 클리어사이드 바이오메디컬, 인코포레이드 인간 대상체에서 안구 질병을 치료하기 위한 방법 및 장치
ES2930433T3 (es) 2013-03-05 2022-12-12 Univ Pittsburgh Commonwealth Sys Higher Education Hidrogel termosensible que contiene micropartículas de polímero para la administración ocular no invasiva de fármaco
KR102433489B1 (ko) 2013-03-14 2022-08-17 팬옵티카, 인크. 눈의 후안부로의 약물 전달을 위한 안구용 제제
US11376329B2 (en) 2013-03-15 2022-07-05 Trustees Of Tufts College Low molecular weight silk compositions and stabilizing silk compositions
KR102457668B1 (ko) 2013-03-15 2022-10-21 트러스티즈 오브 터프츠 칼리지 저분자량 실크 조성물 및 안정화 실크 조성물
EP4137139A1 (en) 2013-07-10 2023-02-22 Matrix Biology Institute Compositions of hyaluronan with high elasticity and uses thereof
US20160279055A1 (en) 2013-07-22 2016-09-29 Imprimis Pharmaceuticals, Inc. Pharmaceutical ophthalmic compositions for intraocular administration and methods for fabricating thereof
US20150129457A1 (en) * 2013-07-22 2015-05-14 Imprimis Pharmaceuticals, Inc. Pharmaceutical compositions for intraocular administration and methods for fabricating thereof
US20150164882A1 (en) 2013-07-22 2015-06-18 Imprimis Pharmaceuticals, Inc. Pharmaceutical compositions for intraocular administration and methods for fabricating thereof
CN104667287B (zh) * 2013-11-27 2018-02-06 山东博士伦福瑞达制药有限公司 用于治疗眼后房新生血管增生的眼用组合物及其用途
CN103656746A (zh) * 2013-12-13 2014-03-26 无锡合众信息科技有限公司 一种可自愈水凝胶玻璃体填充物及其制备方法
JP2017501834A (ja) * 2014-01-08 2017-01-19 サーキット セラピューティクス, インコーポレイテッド 高眼圧症の治療管理のための方法
CA2936239A1 (en) * 2014-01-16 2015-07-23 Ontogenesis, Llc Compositions and methods for the treatment of intraocular neovascularization and/or leakage
EP3102250B1 (en) 2014-02-04 2020-05-13 AMSilk GmbH Coated silk films, methods for the production thereof and uses thereof
CN104027847B (zh) * 2014-06-20 2015-08-26 西安交通大学 一种附带血管网流道的人工软组织体的制造方法
US9840553B2 (en) 2014-06-28 2017-12-12 Kodiak Sciences Inc. Dual PDGF/VEGF antagonists
US9394355B2 (en) 2014-08-20 2016-07-19 Silk Technologies, Ltd. Fibroin-derived protein composition
ES2863601T3 (es) * 2014-09-17 2021-10-11 Panoptica Inc Formulaciones oculares para administración de fármacos y protección del segmento anterior del ojo
CN104368046B (zh) * 2014-11-10 2016-01-13 四川大学 一种纤维增强型载药水凝胶人工角膜裙边支架及其制备方法
CN107205922A (zh) * 2014-12-10 2017-09-26 因赛普特有限责任公司 水凝胶药物递送植入物
CN104587531B (zh) * 2014-12-25 2016-05-04 南京臻泉医药科技有限公司 一种修复关节软骨损伤的凝胶支架的制备方法
US20160303281A1 (en) * 2015-04-17 2016-10-20 Rochal Industries, Llc Composition and kits for pseudoplastic microgel matrices
US10816823B2 (en) 2015-05-04 2020-10-27 École Polytechnique Fédérale de Lausanne Ophthalmic contact lens with compressible affinity matrix
ES2971096T3 (es) 2015-06-06 2024-06-03 Cloudbreak Therapeutics Llc Composiciones y métodos para tratar el terigio
TWI664965B (zh) 2015-06-22 2019-07-11 新源生物科技股份有限公司 酪胺酸激酶抑制劑之眼用調配物、其使用方法、及其製備方法
CN105169476B (zh) * 2015-09-15 2018-06-22 王岩松 一种医用原位凝胶的制备方法及其应用
ES2871199T3 (es) 2015-09-24 2021-10-28 Matrix Biology Inst Composiciones de hialuronano de alta elasticidad y métodos de uso de las mismas
WO2017053686A1 (en) * 2015-09-24 2017-03-30 Massachusetts Eye And Ear Infirmary Drug delivery system and methods of use
CN106692977A (zh) * 2015-11-11 2017-05-24 陶虎 一种蚕丝蛋白胶囊及其制备方法
KR20250057128A (ko) 2015-12-30 2025-04-28 코디악 사이언시스 인코포레이티드 항체 및 이의 접합체
EP3400014A1 (en) * 2016-01-08 2018-11-14 Clearside Biomedical, Inc. Methods and devices for treating posterior ocular disorderswith aflibercept and other biologics
WO2017165449A1 (en) * 2016-03-22 2017-09-28 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Thermoresponsive hydrogel containing polymer microparticles for noninvasive ocular biologic delivery
US10953132B2 (en) 2016-04-08 2021-03-23 Cornell University Method to enhance wound healing using silk-derived protein
LT3245988T (lt) 2016-05-18 2024-02-12 Sonikure Holdings Limited Ultragarsu pagerinto transsklerinio vaistų pristatymo sistema
CA3026118A1 (en) 2016-06-02 2017-12-07 Cloudbreak Therapeutics, Llc Compositions and methods of using nintedanib for treating ocular diseases with abnormal neovascularization
US11395853B2 (en) 2016-06-23 2022-07-26 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Biomimetic drug delivery of an immunomodulatory agent for the treatment of ocular conditions
US11278546B2 (en) * 2016-07-22 2022-03-22 Aiviva Biopharma, Inc. Multikinase inhibitors and uses in ocular fibrosis
AU2017310520A1 (en) 2016-08-12 2019-03-21 Silk Technologies, Ltd. Silk-derived protein for treating inflammation
JP2019529400A (ja) * 2016-09-09 2019-10-17 コーネル・ユニバーシティーCornell University 硝子体小胞中の核酸、タンパク質及び小分子の送達方法
ES2912105T3 (es) * 2016-09-13 2022-05-24 Kyowa Kirin Co Ltd Composición medicinal que comprende tivozanib.
CN111343970A (zh) 2017-09-13 2020-06-26 北卡罗莱纳州立大学 微针贴片局部诱导脂肪组织褐变治疗肥胖症
US20210236644A1 (en) 2017-11-10 2021-08-05 Cocoon Biotech Inc. Ocular applications of silk-based products
CN108079431A (zh) * 2018-02-12 2018-05-29 南通纺织丝绸产业技术研究院 一种多层丝素蛋白复合针壁微针
CN108310618A (zh) * 2018-02-12 2018-07-24 南通纺织丝绸产业技术研究院 一种多层复合针壁丝素蛋白微针及其制备方法
CN108392728A (zh) * 2018-02-12 2018-08-14 南通纺织丝绸产业技术研究院 一种丝素蛋白多层复合微针及其制备方法
WO2019162951A1 (en) * 2018-02-26 2019-08-29 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd Drug delivery systems
US12071476B2 (en) 2018-03-02 2024-08-27 Kodiak Sciences Inc. IL-6 antibodies and fusion constructs and conjugates thereof
CN112368011A (zh) * 2018-04-11 2021-02-12 俄亥俄州创新基金会 缓释微粒用于眼用药物递送的方法和组合物
WO2020056064A1 (en) * 2018-09-11 2020-03-19 Stanley Satz Tumor targeted radionuclide therapy and molecular imaging of her2+ cancers and other neoplasms, and precision medicine.
WO2020061550A1 (en) 2018-09-21 2020-03-26 Aufbau Medical Innovations Limited Compositions and methods for glaucoma
WO2020102810A1 (en) 2018-11-16 2020-05-22 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Thermoresponsive gel eye drop for ocular delivery of cysteamine
KR20210138596A (ko) * 2019-02-08 2021-11-19 오하이오 스테이트 이노베이션 파운데이션 치료제의 안구 투여용 약물전달 조성물 및 이의 사용방법
EP3934646A4 (en) * 2019-03-05 2022-12-14 Aerie Pharmaceuticals, Inc. PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF EYE DISEASES OR CONDITIONS
US11883525B2 (en) 2019-05-31 2024-01-30 Dose Medical Corporation Bioerodible polyester polymer axitinib ocular implants and related methods of use
WO2020247594A1 (en) 2019-06-04 2020-12-10 Cocoon Biotech Inc. Silk-based products, formulations, and methods of use
MA54325A (fr) 2019-06-05 2022-05-11 Regeneron Pharma Dispositifs et procédés pour l'administration précise de doses
AU2020364071A1 (en) 2019-10-10 2022-05-26 Kodiak Sciences Inc. Methods of treating an eye disorder
US20210127976A1 (en) * 2019-11-01 2021-05-06 Koninklijke Philips N.V. System and method for assessing preparedness for imaging procedures
WO2021141672A2 (en) * 2019-11-15 2021-07-15 Silk Technologies, Ltd. Stable formulations of silk-derived protein
PT3884929T (pt) * 2020-03-25 2023-08-09 Ocular Therapeutix Inc Implante ocular contendo um inibidor da tirosina cinase
WO2021205471A1 (en) * 2020-04-06 2021-10-14 Jawaharlal Nehru Centre For Advanced Scientific Research Composition, injectable hydrogel and methods thereof
CN113440604B (zh) * 2021-06-24 2022-05-31 浙江泽瑞生物医药有限公司 一种有效抑制血糖的索马鲁肽的口服缓释片剂及其制备方法
WO2023039168A1 (en) * 2021-09-09 2023-03-16 The Board Of Trustees Of The Leland Stanford Junior University Use of verteporfin to modulate wound healing after an ocular surgical procedure or ocular injury
EP4536694A1 (en) 2022-06-07 2025-04-16 Adverum Biotechnologies, Inc. Melanopsin variants for vision restoration
USD1120314S1 (en) 2022-11-30 2026-03-24 Regeneron Pharmaceuticals, Inc. Dose delivery device
AU2024251447A1 (en) 2023-04-11 2025-08-21 Ocular Therapeutix, Inc. Ocular implant comprising axitinib polymorph iv
CN116687840B (zh) * 2023-08-03 2023-10-20 四川省医学科学院·四川省人民医院 一种用于治疗眼部病状的凝胶制剂及其制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1505542A1 (ru) * 1988-01-13 1989-09-07 А. И. Иголкин Медицинска пипетка А.И.Иголкина дл глазных капель
AUPQ496500A0 (en) * 2000-01-06 2000-02-03 University Of Sydney, The Kit
ES2244361T1 (es) * 2002-08-05 2005-12-16 Alcon, Inc. Uso del acetato de anecortave para la proteccion de la agudeza visual en pacientes con degeneracion macular asociada a la edad.
US20070026043A1 (en) * 2003-11-20 2007-02-01 Angiotech International Ag Medical devices combined with diblock copolymer compositions
WO2006083260A2 (en) * 2004-04-28 2006-08-10 Angiotech Biomaterials Corporation Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use
CA2608862C (en) * 2004-06-11 2020-05-05 Trustees Of Tufts College Silk-based drug delivery system
JP2009540011A (ja) * 2006-06-12 2009-11-19 エクセジェニックス、インク.ディー/ビー/エー オプコ ヘルス、インク. 血管新生のsiRNA阻害のための組成物及び方法
EA019118B1 (ru) * 2007-05-29 2014-01-30 Трастиз Оф Тафтс Колледж Способ желатинизации фиброина шелка и регулирования времени желатинизации, способ инкапсуляции по меньшей мере одного компонента в фиброин шелка (варианты)
US20110206773A1 (en) * 2008-05-20 2011-08-25 Yale University Sustained delivery of drugs from biodegradable polymeric microparticles
US20110111031A1 (en) * 2009-04-20 2011-05-12 Guang-Liang Jiang Drug Delivery Platforms Comprising Silk Fibroin Hydrogels and Uses Thereof
ES2443045T5 (es) * 2009-04-20 2021-05-10 Allergan Inc Hidrogeles de fibroína de seda y usos de éstos
US9603971B2 (en) * 2010-03-05 2017-03-28 Trustees Of Tufts College Silk-based ionomeric compositions
AR080888A1 (es) * 2010-04-12 2012-05-16 R Tech Ueno Ltd Uso de un derivado de acido graso para producir una composicion oftalmica

Similar Documents

Publication Publication Date Title
US20170173161A1 (en) Compositions and methods for ocular delivery of a therapeutic agent
Liu et al. Characterization of biodegradable microsphere-hydrogel ocular drug delivery system for controlled and extended release of ranibizumab
JP6132964B2 (ja) 萎縮性加齢性黄斑変性の処置方法
US12357564B2 (en) Methods and compositions for sustained release microparticles for ocular drug delivery
JP7636334B2 (ja) 治療物質の眼投与のための薬物送達組成物及びその使用法
JP6980671B2 (ja) 眼科用組成物
CA2901280A1 (en) Sustained drug delivery implant
US20100098772A1 (en) Drug delivery systems and methods for treating neovascularization
Robert et al. A drug delivery system for administration of anti–TNF-α antibody
Heljak et al. Investigating bevacizumab and its fragments sustained release from intravitreal administrated PLGA microspheres: a modeling approach
KR20190110101A (ko) 안구내 약물 전달 장치 및 관련 방법들
Robert et al. A Drug Delivery System for Administration of Anti–TNF-a Antibody
HK40012677A (en) Treating atrophic age related macular degeneration
AU2013245543A1 (en) Intraocular drug delivery device and associated methods
HK1190092A (en) Bevacizumab for use in a method for treating atrophic age related macular degeneration