JP2015508104A5 - - Google Patents

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Publication number
JP2015508104A5
JP2015508104A5 JP2014558897A JP2014558897A JP2015508104A5 JP 2015508104 A5 JP2015508104 A5 JP 2015508104A5 JP 2014558897 A JP2014558897 A JP 2014558897A JP 2014558897 A JP2014558897 A JP 2014558897A JP 2015508104 A5 JP2015508104 A5 JP 2015508104A5
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JP
Japan
Prior art keywords
composition
therapeutic agent
silk
silk matrix
composition according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2014558897A
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English (en)
Japanese (ja)
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JP2015508104A (ja
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Priority claimed from PCT/US2013/027465 external-priority patent/WO2013126799A1/en
Publication of JP2015508104A publication Critical patent/JP2015508104A/ja
Publication of JP2015508104A5 publication Critical patent/JP2015508104A5/ja
Pending legal-status Critical Current

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JP2014558897A 2012-02-22 2013-02-22 治療薬の眼への送達のための組成物および方法 Pending JP2015508104A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261601924P 2012-02-22 2012-02-22
US61/601,924 2012-02-22
PCT/US2013/027465 WO2013126799A1 (en) 2012-02-22 2013-02-22 Compositions and methods for ocular delivery of a therapeutic agent

Publications (2)

Publication Number Publication Date
JP2015508104A JP2015508104A (ja) 2015-03-16
JP2015508104A5 true JP2015508104A5 (enExample) 2016-04-14

Family

ID=49006267

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014558897A Pending JP2015508104A (ja) 2012-02-22 2013-02-22 治療薬の眼への送達のための組成物および方法

Country Status (6)

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US (2) US20150037422A1 (enExample)
EP (1) EP2817031A4 (enExample)
JP (1) JP2015508104A (enExample)
CA (1) CA2865132A1 (enExample)
HK (1) HK1205461A1 (enExample)
WO (1) WO2013126799A1 (enExample)

Families Citing this family (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX373894B (es) * 2012-11-08 2020-07-09 Clearside Biomedical Inc Métodos y dispositivos para el tratamiento de trastornos oculares en sujetos humanos.
ES2930433T3 (es) 2013-03-05 2022-12-12 Univ Pittsburgh Commonwealth Sys Higher Education Hidrogel termosensible que contiene micropartículas de polímero para la administración ocular no invasiva de fármaco
WO2014152661A1 (en) 2013-03-14 2014-09-25 Panoptica, Inc. Ocular formulations for drug-delivery to the posterior segment of the eye
US11376329B2 (en) 2013-03-15 2022-07-05 Trustees Of Tufts College Low molecular weight silk compositions and stabilizing silk compositions
AU2014233480B2 (en) 2013-03-15 2018-08-09 Trustees Of Tufts College Low molecular weight silk compositions and stabilizing silk compositions
ES2837626T3 (es) 2013-07-10 2021-07-01 Matrix Biology Inst Composiciones de hialuronano con alta elasticidad y usos de las mismas
US20150129457A1 (en) * 2013-07-22 2015-05-14 Imprimis Pharmaceuticals, Inc. Pharmaceutical compositions for intraocular administration and methods for fabricating thereof
US20150164882A1 (en) 2013-07-22 2015-06-18 Imprimis Pharmaceuticals, Inc. Pharmaceutical compositions for intraocular administration and methods for fabricating thereof
US20160279055A1 (en) 2013-07-22 2016-09-29 Imprimis Pharmaceuticals, Inc. Pharmaceutical ophthalmic compositions for intraocular administration and methods for fabricating thereof
CN104667287B (zh) * 2013-11-27 2018-02-06 山东博士伦福瑞达制药有限公司 用于治疗眼后房新生血管增生的眼用组合物及其用途
CN103656746A (zh) * 2013-12-13 2014-03-26 无锡合众信息科技有限公司 一种可自愈水凝胶玻璃体填充物及其制备方法
AU2015204691A1 (en) * 2014-01-08 2016-07-21 Circuit Therapeutics, Inc. Method for therapeutic management of ocular hypertension
CA2936239A1 (en) * 2014-01-16 2015-07-23 Ontogenesis, Llc Compositions and methods for the treatment of intraocular neovascularization and/or leakage
EP3102250B1 (en) * 2014-02-04 2020-05-13 AMSilk GmbH Coated silk films, methods for the production thereof and uses thereof
CN104027847B (zh) * 2014-06-20 2015-08-26 西安交通大学 一种附带血管网流道的人工软组织体的制造方法
US9840553B2 (en) 2014-06-28 2017-12-12 Kodiak Sciences Inc. Dual PDGF/VEGF antagonists
CA2994222C (en) 2014-08-20 2020-09-08 Silk Technologies, Ltd. Fibroin-derived protein composition
RU2768652C1 (ru) * 2014-09-17 2022-03-24 Паноптика, Инк. Офтальмологические составы для доставки лекарств и защиты переднего отдела глаза
CN104368046B (zh) * 2014-11-10 2016-01-13 四川大学 一种纤维增强型载药水凝胶人工角膜裙边支架及其制备方法
AU2015360469B2 (en) * 2014-12-10 2021-03-25 Incept, Llc Hydrogel drug delivery implants
CN104587531B (zh) * 2014-12-25 2016-05-04 南京臻泉医药科技有限公司 一种修复关节软骨损伤的凝胶支架的制备方法
US20160303281A1 (en) * 2015-04-17 2016-10-20 Rochal Industries, Llc Composition and kits for pseudoplastic microgel matrices
US10816823B2 (en) 2015-05-04 2020-10-27 École Polytechnique Fédérale de Lausanne Ophthalmic contact lens with compressible affinity matrix
KR20260025887A (ko) 2015-06-06 2026-02-24 클라우드브레이크 테라퓨틱스, 엘엘씨 익상편을 치료하기 위한 조성물 및 방법
TWI700085B (zh) 2015-06-22 2020-08-01 新源生物科技股份有限公司 酪胺酸激酶抑制劑之眼用調配物的用途
CN105169476B (zh) * 2015-09-15 2018-06-22 王岩松 一种医用原位凝胶的制备方法及其应用
ES2871199T3 (es) 2015-09-24 2021-10-28 Matrix Biology Inst Composiciones de hialuronano de alta elasticidad y métodos de uso de las mismas
US11173130B2 (en) 2015-09-24 2021-11-16 Massachusetts Eye And Ear Infirmary Drug delivery system and methods of use
CN106692977A (zh) * 2015-11-11 2017-05-24 陶虎 一种蚕丝蛋白胶囊及其制备方法
KR20250057128A (ko) 2015-12-30 2025-04-28 코디악 사이언시스 인코포레이티드 항체 및 이의 접합체
CA3010862A1 (en) * 2016-01-08 2017-07-13 Clearside Biomedical, Inc. Methods and devices for treating posterior ocular disorderswith aflibercept and other biologics
US20190099365A1 (en) * 2016-03-22 2019-04-04 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Thermoresponsive hydrogel containing polymer microparticles for noninvasive ocular biologic delivery
SG11201808804TA (en) 2016-04-08 2018-11-29 Univ Cornell A method to enhance wound healing using silk-derived protein
EP3245988B1 (en) 2016-05-18 2023-12-27 Sonikure Holdings Limited System for ultrasound-enhanced transscleral delivery of drugs
AU2017274195B2 (en) 2016-06-02 2022-04-07 Ads Therapeutics Llc Compositions and methods of using nintedanib for improving glaucoma surgery success
US11395853B2 (en) 2016-06-23 2022-07-26 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Biomimetic drug delivery of an immunomodulatory agent for the treatment of ocular conditions
US11278546B2 (en) * 2016-07-22 2022-03-22 Aiviva Biopharma, Inc. Multikinase inhibitors and uses in ocular fibrosis
US11242367B2 (en) 2016-08-12 2022-02-08 Silk Technologies, Ltd. Silk-derived protein for treating inflammation
EP3512948A4 (en) * 2016-09-09 2020-05-13 Cornell University ADMINISTRATION OF NUCLEIC ACIDS, PROTEINS AND SMALL MOLECULES IN GLASS-LIKE VESICULAR BODIES
JP6328860B1 (ja) 2016-09-13 2018-05-23 協和発酵キリン株式会社 医薬組成物
WO2019055594A1 (en) 2017-09-13 2019-03-21 North Carolina State University BRUSHING ADIPOSE TISSUE INDUCED LOCALLY BY MICRO-NEEDLE STAMPS FOR THE TREATMENT OF OBESITY
WO2019094702A1 (en) * 2017-11-10 2019-05-16 Cocoon Biotech Inc. Ocular applications of silk-based products
CN108392728A (zh) * 2018-02-12 2018-08-14 南通纺织丝绸产业技术研究院 一种丝素蛋白多层复合微针及其制备方法
CN108310618A (zh) * 2018-02-12 2018-07-24 南通纺织丝绸产业技术研究院 一种多层复合针壁丝素蛋白微针及其制备方法
CN108079431A (zh) * 2018-02-12 2018-05-29 南通纺织丝绸产业技术研究院 一种多层丝素蛋白复合针壁微针
WO2019162951A1 (en) * 2018-02-26 2019-08-29 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd Drug delivery systems
EP3758737A4 (en) 2018-03-02 2022-10-12 Kodiak Sciences Inc. IL-6 ANTIBODIES AND FUSION CONSTRUCTS AND CONJUGATES THEREOF
BR112020020930A2 (pt) 2018-04-11 2021-03-02 Ohio State Innovation Foundation composição de liberação de fármaco, método para tratar um distúrbio oftalmológico e kit
US20200085979A1 (en) * 2018-09-11 2020-03-19 Stanley Satz Precision medicine theranostics and diagnostics a combination thereof
AU2019343188A1 (en) 2018-09-21 2021-05-20 Aufbau Medical Innovations Limited Compositions and methods for glaucoma
US12599577B2 (en) 2018-11-16 2026-04-14 University of Pittsburgh—of the Commonwealth System of Higher Education Thermoresponsive gel eye drop for ocular delivery of cysteamine
KR20210138596A (ko) * 2019-02-08 2021-11-19 오하이오 스테이트 이노베이션 파운데이션 치료제의 안구 투여용 약물전달 조성물 및 이의 사용방법
KR20210135560A (ko) * 2019-03-05 2021-11-15 에어리 파마슈티컬즈, 인코포레이티드 안구 질환 또는 장애를 치료하는 약학 조성물
WO2020243608A1 (en) * 2019-05-31 2020-12-03 Dose Medical Corporation Bioerodible polyester polymer implants and related methods of use
CA3142608A1 (en) 2019-06-04 2020-12-10 Cocoon Biotech Inc. Silk-based products, formulations, and methods of use
EP3886946A1 (en) 2019-06-05 2021-10-06 Regeneron Pharmaceuticals, Inc. Devices and methods for precision dose delivery
CA3157509A1 (en) 2019-10-10 2021-04-15 Kodiak Sciences Inc. Methods of treating an eye disorder
US20210127976A1 (en) * 2019-11-01 2021-05-06 Koninklijke Philips N.V. System and method for assessing preparedness for imaging procedures
AU2020419590A1 (en) * 2019-11-15 2022-06-30 Silk Technologies, Ltd. Stable formulations of silk-derived protein
PT3884929T (pt) * 2020-03-25 2023-08-09 Ocular Therapeutix Inc Implante ocular contendo um inibidor da tirosina cinase
WO2021205471A1 (en) * 2020-04-06 2021-10-14 Jawaharlal Nehru Centre For Advanced Scientific Research Composition, injectable hydrogel and methods thereof
CN113440604B (zh) * 2021-06-24 2022-05-31 浙江泽瑞生物医药有限公司 一种有效抑制血糖的索马鲁肽的口服缓释片剂及其制备方法
US20240366565A1 (en) * 2021-09-09 2024-11-07 The Board Of Trustees Of The Leland Stanford Junior University Use of Verteporfin to Modulate Wound Healing After an Ocular Surgical Procedure or Ocular Injury
JP2025519378A (ja) 2022-06-07 2025-06-26 アドヴェラム バイオテクノロジーズ, インコーポレイテッド 視覚回復のためのメラノプシンバリアント
USD1120314S1 (en) 2022-11-30 2026-03-24 Regeneron Pharmaceuticals, Inc. Dose delivery device
PE20260040A1 (es) 2023-04-11 2026-01-09 Ocular Therapeutix Inc Implante ocular que contiene un inhibidor de la tirosina cinasa
CN116687840B (zh) * 2023-08-03 2023-10-20 四川省医学科学院·四川省人民医院 一种用于治疗眼部病状的凝胶制剂及其制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1505542A1 (ru) * 1988-01-13 1989-09-07 А. И. Иголкин Медицинска пипетка А.И.Иголкина дл глазных капель
AUPQ496500A0 (en) * 2000-01-06 2000-02-03 University Of Sydney, The Kit
ES2244361T1 (es) * 2002-08-05 2005-12-16 Alcon, Inc. Uso del acetato de anecortave para la proteccion de la agudeza visual en pacientes con degeneracion macular asociada a la edad.
US20070026043A1 (en) * 2003-11-20 2007-02-01 Angiotech International Ag Medical devices combined with diblock copolymer compositions
CN104174071A (zh) * 2004-04-28 2014-12-03 安希奥设备国际有限责任公司 用于形成交联生物材料的组合物和系统及关联的制备方法与用途
CA2608862C (en) * 2004-06-11 2020-05-05 Trustees Of Tufts College Silk-based drug delivery system
DK2029746T3 (da) * 2006-06-12 2012-10-08 Exegenics Inc D B A Opko Health Inc Sammensætninger og fremgangsmåder til siRNA-hæmning af angiogenese
US8187616B2 (en) * 2007-05-29 2012-05-29 Trustees Of Tufts College Method for silk fibroin gelation using sonication
US20110206773A1 (en) * 2008-05-20 2011-08-25 Yale University Sustained delivery of drugs from biodegradable polymeric microparticles
US20110111031A1 (en) * 2009-04-20 2011-05-12 Guang-Liang Jiang Drug Delivery Platforms Comprising Silk Fibroin Hydrogels and Uses Thereof
EP2421549B1 (en) * 2009-04-20 2013-06-12 Allergan, Inc. Silk fibroin hydrogels and uses thereof
WO2011109691A2 (en) * 2010-03-05 2011-09-09 Trustees Of Tufts College Silk-based ionomeric compositions
KR20130050939A (ko) * 2010-04-12 2013-05-16 가부시키가이샤 아루떼꾸 우에노 망막 질환의 치료 방법 및 이를 위한 안과용 조성물

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