JP2015504048A5 - - Google Patents
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- Publication number
- JP2015504048A5 JP2015504048A5 JP2014548945A JP2014548945A JP2015504048A5 JP 2015504048 A5 JP2015504048 A5 JP 2015504048A5 JP 2014548945 A JP2014548945 A JP 2014548945A JP 2014548945 A JP2014548945 A JP 2014548945A JP 2015504048 A5 JP2015504048 A5 JP 2015504048A5
- Authority
- JP
- Japan
- Prior art keywords
- heterocyclyl
- arylalkyl
- heteroaryl
- alkynyl
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 CCC(*)C(*)(*(C)C(*)=O)N(*)CC Chemical compound CCC(*)C(*)(*(C)C(*)=O)N(*)CC 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161578652P | 2011-12-21 | 2011-12-21 | |
| US201161578646P | 2011-12-21 | 2011-12-21 | |
| US61/578,646 | 2011-12-21 | ||
| US61/578,652 | 2011-12-21 | ||
| PCT/US2012/071223 WO2013096755A1 (en) | 2011-12-21 | 2012-12-21 | Proteolytically resistant hydrogen bond surrogate helices |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015504048A JP2015504048A (ja) | 2015-02-05 |
| JP2015504048A5 true JP2015504048A5 (https=) | 2016-02-18 |
Family
ID=48669532
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014548945A Pending JP2015504048A (ja) | 2011-12-21 | 2012-12-21 | タンパク質分解抵抗性水素結合サロゲートヘリックス |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9376469B2 (https=) |
| EP (1) | EP2793920A4 (https=) |
| JP (1) | JP2015504048A (https=) |
| CN (1) | CN104066435A (https=) |
| CA (1) | CA2895930A1 (https=) |
| WO (1) | WO2013096755A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103889437A (zh) * | 2011-08-31 | 2014-06-25 | 纽约大学 | 硫醚、醚和烷基胺连接的氢键替代物肽模拟物 |
| US20140205681A1 (en) * | 2013-01-19 | 2014-07-24 | New York University | HYDROGEN-BOND SURROGATE PEPTIDES AND PEPTIDOMIMETICS FOR p53 REACTIVATION |
| US20150065436A1 (en) * | 2013-09-03 | 2015-03-05 | University Of Southern California | INHIBITING INTERACTION BETWEEN HIF-1ALPHA AND p300/CBP WITH HYDROGEN BOND SURROGATE-BASED HELICES |
| US20170066801A1 (en) * | 2014-02-22 | 2017-03-09 | New York University | Alpha3beta hydrogen bond surrogate macrocycles as modulators of ras |
| SG11201608303QA (en) | 2014-04-04 | 2016-11-29 | Del Mar Pharmaceuticals | Use of dianhydrogalactitol and analogs or derivatives thereof to treat non-small-cell carcinoma of the lung and ovarian cancer |
| CN108024987A (zh) * | 2014-10-10 | 2018-05-11 | 德玛医药 | 用于治疗癌症的二去水卫矛醇的类似物或衍生物与含铂抗肿瘤药物的组合 |
| US11583589B2 (en) * | 2017-08-23 | 2023-02-21 | Cygenica Limited | Cell membrane penetrating conjugates |
| JP7561364B2 (ja) * | 2020-04-30 | 2024-10-04 | 国立大学法人東北大学 | 蛍光偏光免疫分析法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7202332B2 (en) | 2004-05-27 | 2007-04-10 | New York University | Methods for preparing internally constrained peptides and peptidomimetics |
| US8592377B2 (en) * | 2007-03-28 | 2013-11-26 | President And Fellows Of Harvard College | Stitched polypeptides |
| WO2010033879A2 (en) | 2008-09-18 | 2010-03-25 | New York University | Inhibiting interaction between hif-1a and p300/cbp with hydrogen bond surrogate-based helices |
| BRPI0920889A2 (pt) * | 2008-09-22 | 2017-10-10 | Aileron Therapeutics Inc | macrociclos peptidomiméticos. |
| US8835602B2 (en) * | 2009-03-06 | 2014-09-16 | Indian Institute Of Science | Templates for nucleation and propagation of peptide secondary structure |
| CA2772057C (en) * | 2009-09-03 | 2016-02-02 | Strike Bio, Inc. | Targeted delivery using tissue-specific peptidomimetic ligands |
| ES2586411T3 (es) | 2011-03-04 | 2016-10-14 | New York University | Macrociclos sustitutos de enlace de hidrógeno como moduladores de Ras |
| CN103889437A (zh) | 2011-08-31 | 2014-06-25 | 纽约大学 | 硫醚、醚和烷基胺连接的氢键替代物肽模拟物 |
-
2012
- 2012-12-21 US US13/724,887 patent/US9376469B2/en active Active
- 2012-12-21 CN CN201280067761.8A patent/CN104066435A/zh active Pending
- 2012-12-21 WO PCT/US2012/071223 patent/WO2013096755A1/en not_active Ceased
- 2012-12-21 JP JP2014548945A patent/JP2015504048A/ja active Pending
- 2012-12-21 CA CA2895930A patent/CA2895930A1/en not_active Abandoned
- 2012-12-21 EP EP12859663.2A patent/EP2793920A4/en not_active Withdrawn
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