JP2015501642A - 発現カセット - Google Patents

発現カセット Download PDF

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Publication number
JP2015501642A
JP2015501642A JP2014545423A JP2014545423A JP2015501642A JP 2015501642 A JP2015501642 A JP 2015501642A JP 2014545423 A JP2014545423 A JP 2014545423A JP 2014545423 A JP2014545423 A JP 2014545423A JP 2015501642 A JP2015501642 A JP 2015501642A
Authority
JP
Japan
Prior art keywords
genomic dna
promoter
dna sequence
untranslated genomic
expression cassette
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2014545423A
Other languages
English (en)
Japanese (ja)
Other versions
JP2015501642A5 (enExample
Inventor
ルーシェル，ダニエル
アビス−シェル−ガミー，クリステル
モレッティ，ピエール
ベルトシンガー，マルタン
Original Assignee
グレンマーク ファーマシューティカルズ， エセ．アー．
グレンマーク ファーマシューティカルズ， エセ．アー．
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by グレンマーク ファーマシューティカルズ， エセ．アー．, グレンマーク ファーマシューティカルズ， エセ．アー． filed Critical グレンマーク ファーマシューティカルズ， エセ．アー．
Publication of JP2015501642A publication Critical patent/JP2015501642A/ja
Publication of JP2015501642A5 publication Critical patent/JP2015501642A5/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
JP2014545423A 2011-12-07 2012-12-05 発現カセット Pending JP2015501642A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161567675P 2011-12-07 2011-12-07
US61/567,675 2011-12-07
PCT/IB2012/056977 WO2013084157A1 (en) 2011-12-07 2012-12-05 Expression cassette

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2017092184A Division JP2017200476A (ja) 2011-12-07 2017-05-08 発現カセット

Publications (2)

Publication Number Publication Date
JP2015501642A true JP2015501642A (ja) 2015-01-19
JP2015501642A5 JP2015501642A5 (enExample) 2016-01-28

Family

ID=47561694

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2014545423A Pending JP2015501642A (ja) 2011-12-07 2012-12-05 発現カセット
JP2017092184A Pending JP2017200476A (ja) 2011-12-07 2017-05-08 発現カセット
JP2019124927A Active JP7096790B2 (ja) 2011-12-07 2019-07-04 発現カセット

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2017092184A Pending JP2017200476A (ja) 2011-12-07 2017-05-08 発現カセット
JP2019124927A Active JP7096790B2 (ja) 2011-12-07 2019-07-04 発現カセット

Country Status (15)

Country Link
US (3) US20130344604A1 (enExample)
EP (1) EP2788483B1 (enExample)
JP (3) JP2015501642A (enExample)
KR (1) KR102135745B1 (enExample)
CN (1) CN104093834A (enExample)
AU (2) AU2012348558A1 (enExample)
BR (1) BR112014013597A2 (enExample)
CA (1) CA2856479A1 (enExample)
EA (1) EA037273B1 (enExample)
ES (1) ES2679291T3 (enExample)
HK (1) HK1202578A1 (enExample)
IL (1) IL232845A0 (enExample)
MX (1) MX362393B (enExample)
SG (1) SG11201402477VA (enExample)
WO (1) WO2013084157A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX377591B (es) * 2014-10-15 2025-03-10 Amgen Inc Elementos promotores y reguladores para mejorar la expresión de genes heterólogos en células hospederas.
CA2967060A1 (en) * 2014-11-10 2016-05-19 Murdoch Childrens Research Institute Vectors and methods for targeted integration in loci comprising constitutively expressed genes
CN106868044A (zh) * 2017-02-15 2017-06-20 扬州大学 一种转基因动物毛色报告基因表达盒、表达载体及应用
JP7520719B2 (ja) * 2018-03-21 2024-07-23 アルデブロン，エル．エル．シー． 生成が改良されたウイルス及び非ウイルスのナノプラスミドベクター
CN114540352A (zh) * 2022-02-16 2022-05-27 艾瑞生命科学技术(常州)有限公司 一种多核苷酸、载体元件及表达载体和宿主细胞及应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002014509A1 (en) * 2000-08-10 2002-02-21 Ono Pharmaceutical Co., Ltd. Glycerylaldehyde-3-phosphate dehydrogenase promoter inducing cell death
US20090181427A1 (en) * 2005-12-12 2009-07-16 Research Corporation Technologies, Inc. Hybrid 3' untranslated regions suitable for efficient protein expression in mammalian cells

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3584341D1 (de) * 1984-08-24 1991-11-14 Upjohn Co Rekombinante dna-verbindungen und expression von polypeptiden wie tpa.
KR20000006334A (ko) * 1998-06-26 2000-01-25 이선경 바이러스코딩염기서열이전혀없는고효율레트로바이러스벡터

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002014509A1 (en) * 2000-08-10 2002-02-21 Ono Pharmaceutical Co., Ltd. Glycerylaldehyde-3-phosphate dehydrogenase promoter inducing cell death
US20090181427A1 (en) * 2005-12-12 2009-07-16 Research Corporation Technologies, Inc. Hybrid 3' untranslated regions suitable for efficient protein expression in mammalian cells

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
村松正實ほか編, 分子細胞生物学辞典, 第２版, 2008年10月, 株式会社東京化学同人, P.455,619,620, JPN6016041943, ISSN: 0003433135 *

Also Published As

Publication number Publication date
EP2788483B1 (en) 2018-06-27
MX2014006869A (es) 2014-07-14
EP2788483A1 (en) 2014-10-15
AU2018204332A1 (en) 2018-07-05
AU2012348558A1 (en) 2014-07-10
MX362393B (es) 2019-01-15
JP7096790B2 (ja) 2022-07-06
SG11201402477VA (en) 2014-09-26
WO2013084157A1 (en) 2013-06-13
IL232845A0 (en) 2014-07-31
JP2019193659A (ja) 2019-11-07
US20130344604A1 (en) 2013-12-26
ES2679291T3 (es) 2018-08-23
KR20140113666A (ko) 2014-09-24
US20200087679A1 (en) 2020-03-19
EA037273B1 (ru) 2021-03-02
NZ626252A (en) 2016-06-24
AU2012348558A2 (en) 2014-07-24
BR112014013597A2 (pt) 2020-08-18
EA201491034A1 (ru) 2015-04-30
KR102135745B1 (ko) 2020-07-21
JP2017200476A (ja) 2017-11-09
CA2856479A1 (en) 2013-06-13
HK1202578A1 (en) 2015-10-02
CN104093834A (zh) 2014-10-08
AU2018204332B2 (en) 2020-09-10
US20180163225A1 (en) 2018-06-14

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