BR112014013597A2 - cassete de expressão, vetor de expressão, célula hospedeira, método in vitro para expressão de um polipeptídeo e uso de um cassete de expressão ou vetor de expressão - Google Patents

cassete de expressão, vetor de expressão, célula hospedeira, método in vitro para expressão de um polipeptídeo e uso de um cassete de expressão ou vetor de expressão Download PDF

Info

Publication number
BR112014013597A2
BR112014013597A2 BR112014013597-5A BR112014013597A BR112014013597A2 BR 112014013597 A2 BR112014013597 A2 BR 112014013597A2 BR 112014013597 A BR112014013597 A BR 112014013597A BR 112014013597 A2 BR112014013597 A2 BR 112014013597A2
Authority
BR
Brazil
Prior art keywords
genomic dna
dna sequence
promoter
expression cassette
expression
Prior art date
Application number
BR112014013597-5A
Other languages
English (en)
Portuguese (pt)
Inventor
Daniel Luescher
Christel Aebischer-Gumy
Pierre Moretti
Martin Bertschinger
Original Assignee
Glenmark Pharmaceuticals S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glenmark Pharmaceuticals S.A. filed Critical Glenmark Pharmaceuticals S.A.
Publication of BR112014013597A2 publication Critical patent/BR112014013597A2/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
BR112014013597-5A 2011-12-07 2012-12-05 cassete de expressão, vetor de expressão, célula hospedeira, método in vitro para expressão de um polipeptídeo e uso de um cassete de expressão ou vetor de expressão BR112014013597A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161567675P 2011-12-07 2011-12-07
US61/567,675 2011-12-07
PCT/IB2012/056977 WO2013084157A1 (en) 2011-12-07 2012-12-05 Expression cassette

Publications (1)

Publication Number Publication Date
BR112014013597A2 true BR112014013597A2 (pt) 2020-08-18

Family

ID=47561694

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014013597-5A BR112014013597A2 (pt) 2011-12-07 2012-12-05 cassete de expressão, vetor de expressão, célula hospedeira, método in vitro para expressão de um polipeptídeo e uso de um cassete de expressão ou vetor de expressão

Country Status (15)

Country Link
US (3) US20130344604A1 (enExample)
EP (1) EP2788483B1 (enExample)
JP (3) JP2015501642A (enExample)
KR (1) KR102135745B1 (enExample)
CN (1) CN104093834A (enExample)
AU (2) AU2012348558A1 (enExample)
BR (1) BR112014013597A2 (enExample)
CA (1) CA2856479A1 (enExample)
EA (1) EA037273B1 (enExample)
ES (1) ES2679291T3 (enExample)
HK (1) HK1202578A1 (enExample)
IL (1) IL232845A0 (enExample)
MX (1) MX362393B (enExample)
SG (1) SG11201402477VA (enExample)
WO (1) WO2013084157A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX377591B (es) * 2014-10-15 2025-03-10 Amgen Inc Elementos promotores y reguladores para mejorar la expresión de genes heterólogos en células hospederas.
CA2967060A1 (en) * 2014-11-10 2016-05-19 Murdoch Childrens Research Institute Vectors and methods for targeted integration in loci comprising constitutively expressed genes
CN106868044A (zh) * 2017-02-15 2017-06-20 扬州大学 一种转基因动物毛色报告基因表达盒、表达载体及应用
JP7520719B2 (ja) * 2018-03-21 2024-07-23 アルデブロン,エル.エル.シー. 生成が改良されたウイルス及び非ウイルスのナノプラスミドベクター
CN114540352A (zh) * 2022-02-16 2022-05-27 艾瑞生命科学技术(常州)有限公司 一种多核苷酸、载体元件及表达载体和宿主细胞及应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3584341D1 (de) * 1984-08-24 1991-11-14 Upjohn Co Rekombinante dna-verbindungen und expression von polypeptiden wie tpa.
KR20000006334A (ko) * 1998-06-26 2000-01-25 이선경 바이러스코딩염기서열이전혀없는고효율레트로바이러스벡터
US20040005639A1 (en) * 2000-08-10 2004-01-08 Ryoichi Ishitani Glycerylaldehyde-3-phosphate dehyrogenase promoter inducing cell death
ATE497009T1 (de) * 2005-12-12 2011-02-15 King Faisal Specialist Hospital And Res Ct 3-nichttranslatierte hybridbereiche mit eignung zur effizienten proteinexpression in säugerzellen

Also Published As

Publication number Publication date
JP2015501642A (ja) 2015-01-19
EP2788483B1 (en) 2018-06-27
MX2014006869A (es) 2014-07-14
EP2788483A1 (en) 2014-10-15
AU2018204332A1 (en) 2018-07-05
AU2012348558A1 (en) 2014-07-10
MX362393B (es) 2019-01-15
JP7096790B2 (ja) 2022-07-06
SG11201402477VA (en) 2014-09-26
WO2013084157A1 (en) 2013-06-13
IL232845A0 (en) 2014-07-31
JP2019193659A (ja) 2019-11-07
US20130344604A1 (en) 2013-12-26
ES2679291T3 (es) 2018-08-23
KR20140113666A (ko) 2014-09-24
US20200087679A1 (en) 2020-03-19
EA037273B1 (ru) 2021-03-02
NZ626252A (en) 2016-06-24
AU2012348558A2 (en) 2014-07-24
EA201491034A1 (ru) 2015-04-30
KR102135745B1 (ko) 2020-07-21
JP2017200476A (ja) 2017-11-09
CA2856479A1 (en) 2013-06-13
HK1202578A1 (en) 2015-10-02
CN104093834A (zh) 2014-10-08
AU2018204332B2 (en) 2020-09-10
US20180163225A1 (en) 2018-06-14

Similar Documents

Publication Publication Date Title
KR101812348B1 (ko) 단백질의 생산 방법
US20220282260A1 (en) Dna vectors, transposons and transposases for eukaryotic genome modification
AU2024220126A1 (en) Compositions and methods for making antibodies based on use of an expression-enhancing locus
US20200087679A1 (en) Expression cassette
EP2711428A1 (en) Site-specific integration
EP2898077B1 (en) Expression vectors comprising chimeric cytomegalovirus promoter and enhancer sequences
EP3359671A2 (en) Dna vectors, transposons and transposases for eukaryotic genome modification
CN103038352B (zh) 用于增强基因表达的新型基因间元件
JP2015091238A (ja) 哺乳類発現ベクター
AU2004295590B2 (en) Expression systems using mammalian beta-actin promoter
CN104278032A (zh) 一种新型双启动子结构单元
CN102639699A (zh) Dna构建体以及用其制备重组cho细胞的方法
US9163257B2 (en) Expression vector and methods of producing high levels of proteins
WO2018150345A1 (en) An expression vector
NZ626252B2 (en) Expression cassette
HK1195789A (en) Expression vectors comprising chimeric cytomegalovirus promoter and enhancer sequences
HK1206061B (en) Expression vectors comprising chimeric cytomegalovirus promoter and enhancer sequences

Legal Events

Date Code Title Description
B25D Requested change of name of applicant approved

Owner name: ICHNOS SCIENCES SA (CH)

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements
B350 Update of information on the portal [chapter 15.35 patent gazette]