JP2015154774A5 - - Google Patents
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- JP2015154774A5 JP2015154774A5 JP2015059131A JP2015059131A JP2015154774A5 JP 2015154774 A5 JP2015154774 A5 JP 2015154774A5 JP 2015059131 A JP2015059131 A JP 2015059131A JP 2015059131 A JP2015059131 A JP 2015059131A JP 2015154774 A5 JP2015154774 A5 JP 2015154774A5
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- 230000014509 gene expression Effects 0.000 claims 18
- 108090000623 proteins and genes Proteins 0.000 claims 12
- 238000000034 method Methods 0.000 claims 10
- 101000950669 Homo sapiens Mitogen-activated protein kinase 9 Proteins 0.000 claims 4
- 102100037809 Mitogen-activated protein kinase 9 Human genes 0.000 claims 4
- 230000004083 survival effect Effects 0.000 claims 4
- 102100022416 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 Human genes 0.000 claims 2
- 102100030690 Histone H2B type 1-C/E/F/G/I Human genes 0.000 claims 2
- 101000755762 Homo sapiens Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 Proteins 0.000 claims 2
- 101001084682 Homo sapiens Histone H2B type 1-C/E/F/G/I Proteins 0.000 claims 2
- 101000961145 Homo sapiens Immunoglobulin heavy constant gamma 3 Proteins 0.000 claims 2
- 101000840257 Homo sapiens Immunoglobulin kappa constant Proteins 0.000 claims 2
- 101000852865 Homo sapiens Interferon alpha/beta receptor 2 Proteins 0.000 claims 2
- 101001076422 Homo sapiens Interleukin-1 receptor type 2 Proteins 0.000 claims 2
- 101001052493 Homo sapiens Mitogen-activated protein kinase 1 Proteins 0.000 claims 2
- 101000797990 Homo sapiens Putative activator of 90 kDa heat shock protein ATPase homolog 2 Proteins 0.000 claims 2
- 101000612997 Homo sapiens Tetraspanin-5 Proteins 0.000 claims 2
- 101000610609 Homo sapiens Tumor necrosis factor receptor superfamily member 10D Proteins 0.000 claims 2
- 102100039348 Immunoglobulin heavy constant gamma 3 Human genes 0.000 claims 2
- 102100029572 Immunoglobulin kappa constant Human genes 0.000 claims 2
- 102100036718 Interferon alpha/beta receptor 2 Human genes 0.000 claims 2
- 102100026017 Interleukin-1 receptor type 2 Human genes 0.000 claims 2
- 102000034655 MIF Human genes 0.000 claims 2
- 108060004872 MIF Proteins 0.000 claims 2
- 102100024193 Mitogen-activated protein kinase 1 Human genes 0.000 claims 2
- 102100032319 Putative activator of 90 kDa heat shock protein ATPase homolog 2 Human genes 0.000 claims 2
- 102100040872 Tetraspanin-5 Human genes 0.000 claims 2
- 102100033663 Transforming growth factor beta receptor type 3 Human genes 0.000 claims 2
- 102100040110 Tumor necrosis factor receptor superfamily member 10D Human genes 0.000 claims 2
- 108010079292 betaglycan Proteins 0.000 claims 2
- 210000004369 blood Anatomy 0.000 claims 2
- 239000008280 blood Substances 0.000 claims 2
- 239000003153 chemical reaction reagent Substances 0.000 claims 2
- 238000011156 evaluation Methods 0.000 claims 2
- 108020004707 nucleic acids Proteins 0.000 claims 2
- 150000007523 nucleic acids Chemical class 0.000 claims 2
- 102000039446 nucleic acids Human genes 0.000 claims 2
- 238000001574 biopsy Methods 0.000 claims 1
- 238000005259 measurement Methods 0.000 claims 1
- 210000005259 peripheral blood Anatomy 0.000 claims 1
- 239000011886 peripheral blood Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US66208305P | 2005-03-14 | 2005-03-14 | |
| US60/662,083 | 2005-03-14 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008501966A Division JP2008537875A (ja) | 2005-03-14 | 2006-03-13 | 固形臓器移植レシピエントにおいて移植片生着を評価するための方法および組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015154774A JP2015154774A (ja) | 2015-08-27 |
| JP2015154774A5 true JP2015154774A5 (enExample) | 2016-02-04 |
| JP6178356B2 JP6178356B2 (ja) | 2017-08-09 |
Family
ID=36992379
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008501966A Pending JP2008537875A (ja) | 2005-03-14 | 2006-03-13 | 固形臓器移植レシピエントにおいて移植片生着を評価するための方法および組成物 |
| JP2015059131A Expired - Fee Related JP6178356B2 (ja) | 2005-03-14 | 2015-03-23 | 固形臓器移植レシピエントにおいて移植片生着を評価するための方法および組成物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008501966A Pending JP2008537875A (ja) | 2005-03-14 | 2006-03-13 | 固形臓器移植レシピエントにおいて移植片生着を評価するための方法および組成物 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US7741038B2 (enExample) |
| EP (2) | EP2604703B1 (enExample) |
| JP (2) | JP2008537875A (enExample) |
| CA (1) | CA2601623C (enExample) |
| WO (1) | WO2006099421A2 (enExample) |
Families Citing this family (54)
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| AU2002950779A0 (en) * | 2002-08-15 | 2002-09-12 | The Corporation Of The Trustees Of The Order Of The Sisters Of Mercy In Queensland | A method of immunomodulation |
| CA2957704A1 (en) * | 2004-01-21 | 2005-08-04 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for determining a graft tolerant phenotype in a subject |
| USRE46843E1 (en) | 2005-03-14 | 2018-05-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for evaluating graft survival in a solid organ transplant recipient |
| EP2604703B1 (en) | 2005-03-14 | 2017-02-01 | The Board of Trustees of the Leland Stanford Junior University | Methods for evaluating graft survival in a solid organ transplant recipient |
| US20080233573A1 (en) * | 2006-08-28 | 2008-09-25 | Kathleen Storm | Gene expression profiling for identification, monitoring and treatment of transplant rejection |
| US8003333B2 (en) * | 2007-09-28 | 2011-08-23 | Mayo Foundation For Medical Education And Research | Serum biomarkers for early detection of acute cellular rejection |
| EP2088205A1 (en) | 2008-02-11 | 2009-08-12 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | PSMB10: A diagnosis marker and therapeutic target of chronic rejection. |
| ES2341419B1 (es) * | 2008-08-14 | 2011-05-03 | Hospital Clinic I Provincial De Barcelona | Wnt1 como biomarcador de daño renal. |
| US20110201519A1 (en) * | 2008-08-18 | 2011-08-18 | Sarwal Minnie M | Methods and Compositions for Determining a Graft Tolerant Phenotype in a Subject |
| JP2012501456A (ja) * | 2008-08-28 | 2012-01-19 | アスチュート メディカル，インコーポレイテッド | 腎損傷および腎不全の診断および予後のための方法および組成物 |
| CA2735590A1 (en) * | 2008-08-29 | 2010-03-04 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| EP2767833A3 (en) * | 2008-10-21 | 2014-12-17 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| WO2010048346A1 (en) | 2008-10-21 | 2010-04-29 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| CN104330574B (zh) | 2008-11-10 | 2017-04-12 | 阿斯图特医药公司 | 用于诊断和预后肾损伤和肾衰竭的方法和组合物 |
| EP2364370B1 (en) * | 2008-11-22 | 2014-09-03 | Astute Medical, Inc. | Methods for prognosis of acute renal failure |
| US9938579B2 (en) | 2009-01-15 | 2018-04-10 | The Board Of Trustees Of The Leland Stanford Junior University | Biomarker panel for diagnosis and prediction of graft rejection |
| US9229010B2 (en) | 2009-02-06 | 2016-01-05 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| CA2767616A1 (en) | 2009-07-09 | 2011-01-13 | The Scripps Research Institute | Gene expression profiles associated with chronic allograft nephropathy |
| KR20120061863A (ko) | 2009-08-07 | 2012-06-13 | 아스튜트 메디컬 인코포레이티드 | 신장 손상 및 신부전증의 진단과 예후를 위한 방법 및 조성물 |
| MX340078B (es) | 2009-11-07 | 2016-06-24 | Astute Medical Inc | Metodos y composiciones para el diagnostico y pronostico de daño renal y falla renal. |
| WO2011066380A1 (en) * | 2009-11-25 | 2011-06-03 | The Board Of Trustees Of The Leland Stanford Junior University | Biomarkers for the diagnosis of kidney graft rejection |
| US9290813B2 (en) | 2009-12-02 | 2016-03-22 | The Board Of Trustees Of The Leland Stanford Junior University | Biomarkers for determining an allograft tolerant phenotype |
| MX342967B (es) | 2009-12-20 | 2016-10-19 | Astute Medical Inc | Metodos y composiciones para la diagnosis y prognosis de lesion renal y falla renal. |
| CN102791885B (zh) | 2010-02-05 | 2015-09-09 | 阿斯图特医药公司 | 用于肾损伤和肾衰竭的诊断及预后的方法和组合物 |
| EP2539712A4 (en) | 2010-02-26 | 2013-09-18 | Astute Medical Inc | METHODS AND COMPOSITIONS FOR DIAGNOSIS AND PROGNOSIS OF RENAL INJURY AND RENAL FAILURE |
| CA2794255C (en) | 2010-03-25 | 2020-01-14 | The Board Of Trustees Of The Leland Stanford Junior University | Protein and gene biomarkers for rejection of organ transplants |
| GB201007454D0 (en) * | 2010-05-04 | 2010-06-16 | King S College London | Method of determining tolerance |
| CN105137085A (zh) * | 2010-06-23 | 2015-12-09 | 阿斯图特医药公司 | 用于肾损伤和肾衰竭的诊断及预后的方法和组合物 |
| NZ605698A (en) | 2010-06-23 | 2015-03-27 | Astute Medical Inc | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| US20130210043A1 (en) * | 2010-06-23 | 2013-08-15 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| IN2012MN02812A (enExample) * | 2010-06-23 | 2015-05-22 | Astute Medical Inc | |
| WO2012106632A1 (en) * | 2011-02-03 | 2012-08-09 | The Board Of Trustees Of The Leland Stanford Junior University | Biomarkers for determining an allograft tolerant phenotype |
| WO2012139051A2 (en) | 2011-04-06 | 2012-10-11 | The Board Of Trustees Of The Leland Stanford Junior University | Autoantibody biomarkers for iga nephropathy |
| KR20150044834A (ko) * | 2011-10-24 | 2015-04-27 | 소마로직, 인크. | 질병 바이오마커의 확인 및 샘플의 품질 평가를 위한 바람직한 샘플 핸들링 및 처리 프로토콜의 선별 |
| EP3540440B1 (en) | 2011-12-08 | 2022-09-28 | Astute Medical, Inc. | Methods and uses for evaluating renal injury and renal status |
| JP6681195B2 (ja) | 2013-01-17 | 2020-04-15 | アスチュート メディカル，インコーポレイテッド | 腎損傷および腎不全の診断および予後診断のための方法ならびに組成物 |
| CA2922746A1 (en) * | 2013-09-06 | 2015-03-12 | Immucor Gti Diagnostics, Inc. | Compositions and methods for diagnosis and prediction of solid organ graft rejection |
| CN103675300B (zh) * | 2014-01-03 | 2015-10-14 | 苏州工业园区为真生物医药科技有限公司 | Rbx1作为血清标志物的应用及其试剂盒 |
| US11104951B2 (en) | 2014-05-22 | 2021-08-31 | The Scripps Research Institute | Molecular signatures for distinguishing liver transplant rejections or injuries |
| US10443100B2 (en) | 2014-05-22 | 2019-10-15 | The Scripps Research Institute | Gene expression profiles associated with sub-clinical kidney transplant rejection |
| AU2017277305A1 (en) | 2016-06-06 | 2018-12-20 | Astute Medical, Inc. | Management of acute kidney injury using insulin-like growth factor-binding protein 7 and tissue inhibitor of metalloproteinase 2 |
| US10894960B2 (en) | 2016-08-30 | 2021-01-19 | Children's Hospital Medical Center | Compositions and methods for nucleic acid transfer |
| PT3510167T (pt) * | 2016-09-08 | 2021-10-18 | Inst Nat Sante Rech Med | Métodos e composições para prever disfunção crónica de aloenxerto pulmonar |
| CN110431422A (zh) | 2017-02-06 | 2019-11-08 | 机敏医药股份有限公司 | 用于肾损伤和肾衰竭的诊断和预后的方法和组合物 |
| US12411144B2 (en) | 2017-03-22 | 2025-09-09 | Children's Hospital Medical Center | Compositions and methods for treatment of lung function |
| WO2019107673A1 (ko) * | 2017-11-29 | 2019-06-06 | 서울대학교병원 | Abo 혈액형 부적합 이식시의 항체-매개성 거부반응의 모니터링을 위한 바이오마커 |
| US12618855B2 (en) | 2019-10-08 | 2026-05-05 | Children's Hospital Medical Center | Serum protein biomarker panel for idiopathic pulmonary fibrosis |
| CN111593113A (zh) * | 2020-05-21 | 2020-08-28 | 中国科学院大学宁波华美医院 | 一种基于急性排斥反应新机制的vegf基因结合位点检测方法 |
| US12247978B2 (en) * | 2020-08-05 | 2025-03-11 | Arizona Board Of Regents On Behalf Of Northern Arizona University | Compositions and methods for detection and treatment of coronavirus infection |
| WO2022031877A1 (en) * | 2020-08-05 | 2022-02-10 | Children's Hospital Medical Center | Compositions and methods for the treatment of bronchiolitis obliterans |
| CN111939272B (zh) * | 2020-08-21 | 2023-02-24 | 上海交通大学医学院附属第九人民医院 | Ccn1的用途 |
| CN116042848B (zh) * | 2021-10-28 | 2024-08-09 | 北京干细胞与再生医学研究院 | 一种通过血样检测判断动物体内存在移植物的方法 |
| CN116486922B (zh) * | 2023-04-18 | 2024-01-23 | 中日友好医院(中日友好临床医学研究所) | 一种基于基因多态性及血浆细胞因子的肺移植排斥预测方法及应用 |
| WO2026036182A1 (en) * | 2024-08-15 | 2026-02-19 | The Westmead Institute for Medical Research | Biomarkers and uses therefor |
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| CN102124340B (zh) | 2008-06-02 | 2014-12-17 | 卫材R&D管理有限公司 | IgA肾病的检查方法和检查试剂盒 |
| US20110201519A1 (en) | 2008-08-18 | 2011-08-18 | Sarwal Minnie M | Methods and Compositions for Determining a Graft Tolerant Phenotype in a Subject |
| KR100928403B1 (ko) | 2008-10-01 | 2009-11-26 | 경북대학교 산학협력단 | 티지비엠 신증의 진단용 조성물 및 키트 |
| US9938579B2 (en) | 2009-01-15 | 2018-04-10 | The Board Of Trustees Of The Leland Stanford Junior University | Biomarker panel for diagnosis and prediction of graft rejection |
| US8734786B2 (en) | 2009-09-16 | 2014-05-27 | Northwestern University | Use of ECDI-fixed cell tolerance as a method for preventing allograft rejection |
| JP2013528799A (ja) | 2010-05-13 | 2013-07-11 | ユニバーシティ オブ メディスン アンド デンティストリー オブ ニュー ジャージー | 神経変性疾患の検知および診断のための診断用自己抗体プロファイル |
-
2006
- 2006-03-13 EP EP12197040.4A patent/EP2604703B1/en not_active Expired - Lifetime
- 2006-03-13 JP JP2008501966A patent/JP2008537875A/ja active Pending
- 2006-03-13 US US11/375,681 patent/US7741038B2/en not_active Ceased
- 2006-03-13 WO PCT/US2006/009134 patent/WO2006099421A2/en not_active Ceased
- 2006-03-13 CA CA2601623A patent/CA2601623C/en not_active Expired - Lifetime
- 2006-03-13 EP EP06738217A patent/EP1869213A4/en not_active Withdrawn
-
2012
- 2012-06-21 US US13/529,768 patent/USRE47057E1/en active Active
-
2015
- 2015-03-23 JP JP2015059131A patent/JP6178356B2/ja not_active Expired - Fee Related
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