JP2015128593A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2015128593A5 JP2015128593A5 JP2015002075A JP2015002075A JP2015128593A5 JP 2015128593 A5 JP2015128593 A5 JP 2015128593A5 JP 2015002075 A JP2015002075 A JP 2015002075A JP 2015002075 A JP2015002075 A JP 2015002075A JP 2015128593 A5 JP2015128593 A5 JP 2015128593A5
- Authority
- JP
- Japan
- Prior art keywords
- formulation
- self
- amino acid
- peptidomimetic
- assembling peptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000009472 formulation Methods 0.000 claims 20
- 239000000203 mixture Substances 0.000 claims 20
- 108090000765 processed proteins & peptides Proteins 0.000 claims 12
- 125000000539 amino acid group Chemical group 0.000 claims 10
- 239000000816 peptidomimetic Substances 0.000 claims 8
- 230000002209 hydrophobic effect Effects 0.000 claims 3
- 239000000463 material Substances 0.000 claims 3
- 239000011159 matrix material Substances 0.000 claims 3
- 239000003937 drug carrier Substances 0.000 claims 2
- 150000002500 ions Chemical class 0.000 claims 2
- 239000007788 liquid Substances 0.000 claims 2
- 230000000069 prophylactic effect Effects 0.000 claims 2
- 230000001225 therapeutic effect Effects 0.000 claims 2
- 239000004475 Arginine Substances 0.000 claims 1
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 claims 1
- QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 claims 1
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 claims 1
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 claims 1
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 claims 1
- 239000004472 Lysine Substances 0.000 claims 1
- 235000004279 alanine Nutrition 0.000 claims 1
- 150000001413 amino acids Chemical group 0.000 claims 1
- 229940035676 analgesics Drugs 0.000 claims 1
- 239000000730 antalgic agent Substances 0.000 claims 1
- 239000002260 anti-inflammatory agent Substances 0.000 claims 1
- 229940121363 anti-inflammatory agent Drugs 0.000 claims 1
- 239000004599 antimicrobial Substances 0.000 claims 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims 1
- 235000003704 aspartic acid Nutrition 0.000 claims 1
- 230000004888 barrier function Effects 0.000 claims 1
- OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 239000003086 colorant Substances 0.000 claims 1
- 238000011109 contamination Methods 0.000 claims 1
- 239000000032 diagnostic agent Substances 0.000 claims 1
- 229940039227 diagnostic agent Drugs 0.000 claims 1
- 239000004744 fabric Substances 0.000 claims 1
- 239000012530 fluid Substances 0.000 claims 1
- 235000013922 glutamic acid Nutrition 0.000 claims 1
- 239000004220 glutamic acid Substances 0.000 claims 1
- 239000003102 growth factor Substances 0.000 claims 1
- 239000000017 hydrogel Substances 0.000 claims 1
- 239000007943 implant Substances 0.000 claims 1
- 230000007935 neutral effect Effects 0.000 claims 1
- 235000016709 nutrition Nutrition 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
- 239000005526 vasoconstrictor agent Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/740,284 US9162005B2 (en) | 2005-04-25 | 2007-04-25 | Compositions for prevention of adhesions and other barrier applications |
| US11/740,284 | 2007-04-25 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010506529A Division JP5976272B2 (ja) | 2007-04-25 | 2008-04-25 | 癒着の予防および他のバリア適用のための組成物 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017048126A Division JP6441978B2 (ja) | 2007-04-25 | 2017-03-14 | 癒着の予防および他のバリア適用のための組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015128593A JP2015128593A (ja) | 2015-07-16 |
| JP2015128593A5 true JP2015128593A5 (enExample) | 2015-11-26 |
| JP6113764B2 JP6113764B2 (ja) | 2017-04-12 |
Family
ID=39620203
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010506529A Expired - Fee Related JP5976272B2 (ja) | 2007-04-25 | 2008-04-25 | 癒着の予防および他のバリア適用のための組成物 |
| JP2015002075A Expired - Fee Related JP6113764B2 (ja) | 2007-04-25 | 2015-01-08 | 癒着の予防および他のバリア適用のための組成物 |
| JP2017048126A Expired - Fee Related JP6441978B2 (ja) | 2007-04-25 | 2017-03-14 | 癒着の予防および他のバリア適用のための組成物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010506529A Expired - Fee Related JP5976272B2 (ja) | 2007-04-25 | 2008-04-25 | 癒着の予防および他のバリア適用のための組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017048126A Expired - Fee Related JP6441978B2 (ja) | 2007-04-25 | 2017-03-14 | 癒着の予防および他のバリア適用のための組成物 |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US9162005B2 (enExample) |
| EP (2) | EP2581097B1 (enExample) |
| JP (3) | JP5976272B2 (enExample) |
| CA (1) | CA2722465C (enExample) |
| DK (1) | DK2581097T3 (enExample) |
| ES (1) | ES2639625T3 (enExample) |
| HU (1) | HUE034194T2 (enExample) |
| PL (1) | PL2581097T3 (enExample) |
| WO (1) | WO2008134544A1 (enExample) |
Families Citing this family (85)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4023240A1 (en) * | 2004-07-06 | 2022-07-06 | 3D Matrix, Inc. | Purified amphiphilic peptide compositions and uses thereof |
| US9327010B2 (en) | 2005-04-25 | 2016-05-03 | Massachusetts Institute Of Technology | Compositions and methods for promoting hemostasis and other physiological activities |
| US9162005B2 (en) | 2005-04-25 | 2015-10-20 | Arch Biosurgery, Inc. | Compositions for prevention of adhesions and other barrier applications |
| US9877921B2 (en) * | 2005-09-09 | 2018-01-30 | Nova Southeastern University | Epinephrine nanoparticles, methods of fabrication thereof, and methods for use thereof for treatment of conditions responsive to epinephrine |
| US20160045457A1 (en) | 2005-09-09 | 2016-02-18 | Ousama Rachid | Epinephrine fine particles and methods for use thereof for treatment of conditions responsive to epinephrine |
| US8168181B2 (en) | 2006-02-13 | 2012-05-01 | Alethia Biotherapeutics, Inc. | Methods of impairing osteoclast differentiation using antibodies that bind siglec-15 |
| CA2822302A1 (en) | 2006-02-13 | 2007-08-23 | Alethia Biotherapeutics Inc. | Methods of impairing osteoclast differentiation |
| CN101472620A (zh) | 2006-04-25 | 2009-07-01 | 麻省理工学院 | 用于影响污染物、机体流体或其它实体移动和/或影响其它生理状况的组合物和方法 |
| DK2146733T3 (da) * | 2007-03-14 | 2021-01-11 | Arch Biosurgery Inc | Treatment of leaky or damaged tight junctions and enhancing extracellular matrix |
| US7906478B2 (en) * | 2007-07-20 | 2011-03-15 | The Procter & Gamble Company | Personal-care articles having self-assembling peptides |
| WO2009067711A2 (en) | 2007-11-21 | 2009-05-28 | T.J. Smith & Nephew, Limited | Suction device and dressing |
| GB0722820D0 (en) | 2007-11-21 | 2008-01-02 | Smith & Nephew | Vacuum assisted wound dressing |
| EP3354243A1 (en) | 2007-11-21 | 2018-08-01 | Smith & Nephew PLC | Wound dressing |
| EP2229960B1 (en) * | 2007-12-05 | 2015-04-08 | 3-D Matrix, Ltd. | Wound healing/skin reconstruction material |
| US20130096518A1 (en) | 2007-12-06 | 2013-04-18 | Smith & Nephew Plc | Wound filling apparatuses and methods |
| US11253399B2 (en) | 2007-12-06 | 2022-02-22 | Smith & Nephew Plc | Wound filling apparatuses and methods |
| GB0723875D0 (en) | 2007-12-06 | 2008-01-16 | Smith & Nephew | Wound management |
| GB0803564D0 (en) | 2008-02-27 | 2008-04-02 | Smith & Nephew | Fluid collection |
| GB0808376D0 (en) | 2008-05-08 | 2008-06-18 | Bristol Myers Squibb Co | Wound dressing |
| US9023376B2 (en) * | 2008-06-27 | 2015-05-05 | The University Of Akron | Nanofiber-reinforced composition for application to surgical wounds |
| GB0817796D0 (en) | 2008-09-29 | 2008-11-05 | Convatec Inc | wound dressing |
| EP2345433B1 (en) * | 2008-10-06 | 2017-03-01 | 3-D Matrix, Ltd. | Tissue plug |
| GB0902816D0 (en) | 2009-02-19 | 2009-04-08 | Smith & Nephew | Fluid communication path |
| US9439941B2 (en) | 2009-12-14 | 2016-09-13 | The University Of Hong Kong | Nano cancer barrier device (NCBD) to immobilize and inhibit the division of metastic cancer stem cells |
| US20120322884A1 (en) | 2010-03-01 | 2012-12-20 | University Of Manitoba | Epinephrine nanoparticles, methods of fabrication thereof, and methods for use thereof for treatment of conditions responsive to epinephrine |
| US9061095B2 (en) | 2010-04-27 | 2015-06-23 | Smith & Nephew Plc | Wound dressing and method of use |
| GB201011173D0 (en) | 2010-07-02 | 2010-08-18 | Smith & Nephew | Provision of wound filler |
| US20130281602A1 (en) * | 2010-10-08 | 2013-10-24 | Solvay Sa | Thermo-responsive polymer covalently bound with a peptide |
| BR112013012785A2 (pt) | 2010-11-25 | 2020-10-20 | Bluestar Silicones France Sas | composição i - ii e produtos e usos das mesmas |
| GB201020005D0 (en) | 2010-11-25 | 2011-01-12 | Smith & Nephew | Composition 1-1 |
| GB201020236D0 (en) | 2010-11-30 | 2011-01-12 | Convatec Technologies Inc | A composition for detecting biofilms on viable tissues |
| US8546338B2 (en) | 2010-12-08 | 2013-10-01 | Johnson & Johnson Consumer Companies, Inc. | Self-assembling hydrogels based on dicephalic peptide amphiphiles |
| EP2648794B1 (en) | 2010-12-08 | 2019-08-28 | ConvaTec Technologies Inc. | Wound exudate system accessory |
| US10207031B2 (en) | 2010-12-08 | 2019-02-19 | Convatec Technologies Inc. | Integrated system for assessing wound exudates |
| DK2648795T3 (da) | 2010-12-08 | 2023-03-27 | Convatec Technologies Inc | System til fjernelse af eksudater fra en sårposition |
| GB201115182D0 (en) | 2011-09-02 | 2011-10-19 | Trio Healthcare Ltd | Skin contact material |
| EP2753321B1 (en) * | 2011-10-21 | 2021-12-15 | Nova Southeastern University | Epinephrine nanoparticles, methods of fabrication thereof, and methods for use thereof for treatment of conditions responsive to epinephrine |
| US9243037B2 (en) | 2011-11-10 | 2016-01-26 | Trustees Of Boston College | Gramicidin a mutants that function as antibiotics with improved solubility and reduced toxicity |
| US20150159066A1 (en) | 2011-11-25 | 2015-06-11 | Smith & Nephew Plc | Composition, apparatus, kit and method and uses thereof |
| GB2497406A (en) | 2011-11-29 | 2013-06-12 | Webtec Converting Llc | Dressing with a perforated binder layer |
| GB201120693D0 (en) | 2011-12-01 | 2012-01-11 | Convatec Technologies Inc | Wound dressing for use in vacuum therapy |
| KR101345333B1 (ko) * | 2011-12-30 | 2013-12-30 | 조선대학교산학협력단 | 라이신 및 트립토판 잔기가 ４번 반복된 신규한 항균 및 항진균 펩타이드 및 이의 용도 |
| CA2876883C (en) | 2012-06-15 | 2022-11-01 | Nova Southeastern University | Epinephrine nanoparticles, methods of fabrication thereof, and methods for use thereof for treatment of conditions responsive to epinephrine |
| JP6389170B2 (ja) | 2012-07-06 | 2018-09-12 | スリーディー マトリックス， エルティーディー３−Ｄ Ｍａｔｒｉｘ， Ｌｔｄ． | ペプチド溶液のためのフィル−フィニッシュ過程 |
| WO2014012165A1 (en) | 2012-07-19 | 2014-01-23 | Alethia Biotherapeutics Inc. | Anti-siglec-15 antibodies |
| ES2933048T3 (es) | 2012-08-17 | 2023-01-31 | Amsilk Gmbh | Uso de polipéptidos de autoensamblaje como adhesivos tisulares |
| JP2016507663A (ja) | 2012-12-20 | 2016-03-10 | コンバテック・テクノロジーズ・インコーポレイテッドＣｏｎｖａｔｅｃ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｉｎｃ | 化学修飾セルロース系繊維の加工 |
| KR20160003651A (ko) * | 2013-03-14 | 2016-01-11 | 가부시끼가이샤 쓰리디 매트릭스 | 위장 폐색 예방용 물질 |
| EP2968647B1 (en) | 2013-03-15 | 2022-06-29 | Smith & Nephew plc | Wound dressing sealant and use thereof |
| US20160120706A1 (en) | 2013-03-15 | 2016-05-05 | Smith & Nephew Plc | Wound dressing sealant and use thereof |
| HRP20211286T1 (hr) | 2013-03-22 | 2021-12-24 | Nova Southeastern University | Fine čestice epinefrina i metode njihove korištenja za liječenje stanja koja odgovaraju na epinefrin |
| DE102013211316A1 (de) * | 2013-06-17 | 2014-12-18 | Aesculap Ag | Hämostyptikum |
| CN105658252A (zh) | 2013-08-22 | 2016-06-08 | 阿奇生物外科有限公司 | 用于控制流体移动的可植入网状物 |
| CA2939696C (en) | 2014-03-10 | 2023-01-10 | 3-D Matrix, Ltd. | Self-assembling peptide compositions |
| ES2712608T3 (es) | 2014-03-10 | 2019-05-14 | 3 D Matrix Ltd | Péptidos autoensamblantes para el tratamiento de las bullas pulmonares |
| JP6684719B2 (ja) | 2014-03-10 | 2020-04-22 | 株式会社スリー・ディー・マトリックス | ペプチド組成物の滅菌および濾過 |
| GB2543544A (en) | 2015-10-21 | 2017-04-26 | Brightwake Ltd | Wound dressing |
| WO2017106460A1 (en) * | 2015-12-15 | 2017-06-22 | 3-D Matrix, Ltd. | Self-assembling peptides comprising non-ionic polar amino acids for anti-adhesion |
| WO2017120092A1 (en) | 2016-01-06 | 2017-07-13 | 3-D Matrix, Ltd. | Combination compositions |
| US20190091376A1 (en) * | 2016-03-18 | 2019-03-28 | 3-D Matrix, Ltd. | Preventing Biological Tissue Adhesion |
| US20210023257A1 (en) * | 2016-03-18 | 2021-01-28 | 3-D Matrix, Ltd. | Cerebrospinal fluid leakage occlusion |
| WO2017173069A1 (en) | 2016-03-30 | 2017-10-05 | Convatec Technologies Inc. | Detecting microbial infections in wounds |
| KR20190008199A (ko) | 2016-03-30 | 2019-01-23 | 시노보 게엠베하 | 상처에서 미생물 감염의 검출 방법 |
| GB201608099D0 (en) | 2016-05-09 | 2016-06-22 | Convatec Technologies Inc | Negative pressure wound dressing |
| WO2018005427A1 (en) * | 2016-06-27 | 2018-01-04 | 3-D Matrix, Ltd. | Self-assembling peptide matrix for the prevention of esophageal stricture after endoscopic dissection |
| BR112019000284A2 (pt) | 2016-07-08 | 2019-04-16 | Convatec Technologies Inc. | aparelho de coleta de fluido |
| MX2019000232A (es) | 2016-07-08 | 2019-11-12 | Convatec Technologies Inc | Deteccion de flujo de fluidos. |
| CA3030152A1 (en) | 2016-07-08 | 2018-01-11 | Convatec Technologies Inc. | Flexible negative pressure system |
| WO2019089856A1 (en) | 2017-10-31 | 2019-05-09 | InMEDBio, LLC | Absorbent, breathable and pathogen blocking/killing wound care dressing and fabrication thereof |
| EP3710074B1 (en) | 2017-11-16 | 2024-03-20 | ConvaTec Limited | Fluid collection apparatus |
| EP3723726A1 (en) | 2017-12-15 | 2020-10-21 | 3-D Matrix, Ltd. | Surfactant peptide nanostructures and uses in drug delivery |
| CA3094984A1 (en) | 2018-03-23 | 2019-09-26 | Arch Biosurgery, Inc. | Sap and peptidomimetic compositions for reducing symptoms of inflammation |
| EP3768296B1 (en) | 2018-03-23 | 2023-09-06 | Arch Biosurgery, Inc. | Sap and peptidomimetics for treatment of eye disease |
| WO2020071527A1 (ja) * | 2018-10-05 | 2020-04-09 | 学校法人 久留米大学 | 腸管における潰瘍または瘻孔の治療または予防のための医薬組成物 |
| CA3116730A1 (en) | 2018-10-19 | 2020-04-23 | Nova Southeastern University | Sublingual epinephrine compositions including ph-modifying excipients and penetration enhancers and methods for use thereof |
| CN109513044B (zh) * | 2019-01-29 | 2022-02-18 | 北京颢美细胞基因生物技术有限公司 | 用于微整形的再生组织基质微粒植入剂、制备方法及应用 |
| JP7372316B2 (ja) * | 2019-04-09 | 2023-10-31 | 富士フイルム株式会社 | 内視鏡用架橋体、内視鏡、及び内視鏡用架橋体を形成するための組成物 |
| WO2020245656A1 (en) | 2019-06-03 | 2020-12-10 | Convatec Limited | Methods and devices to disrupt and contain pathogens |
| US11771819B2 (en) | 2019-12-27 | 2023-10-03 | Convatec Limited | Low profile filter devices suitable for use in negative pressure wound therapy systems |
| US11331221B2 (en) | 2019-12-27 | 2022-05-17 | Convatec Limited | Negative pressure wound dressing |
| EP4090350A1 (en) * | 2020-01-13 | 2022-11-23 | Arch Biosurgery, Inc. | Self-assembling peptide gel formulation and methods of use |
| WO2023108026A2 (en) * | 2021-12-08 | 2023-06-15 | Oakgrove Bio Llc | Biological production of histidine-rich peptides |
| EP4635970A1 (en) * | 2022-12-16 | 2025-10-22 | Toagosei Co., Ltd. | Synthetic peptide and construct |
| CN116789854B (zh) * | 2023-06-08 | 2024-04-02 | 东北农业大学 | 兼具细菌捕获与抑菌功能的纳米抗菌肽及制备方法和应用 |
| CN118978602B (zh) * | 2024-07-29 | 2025-06-10 | 东北农业大学 | 一种具有免疫调节功能的pH响应型纳米抗菌肽及其制备方法和应用 |
Family Cites Families (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4098728A (en) * | 1976-01-02 | 1978-07-04 | Solomon Rosenblatt | Medical surgical sponge and method of making same |
| US4211227A (en) * | 1978-07-03 | 1980-07-08 | The Kendall Company | Surgical sponge material |
| US4272398A (en) * | 1978-08-17 | 1981-06-09 | The United States Of America As Represented By The Secretary Of Agriculture | Microencapsulation process |
| US4636208A (en) * | 1984-10-05 | 1987-01-13 | Ewald Rath | Surgical sponge |
| US4829000A (en) | 1985-08-30 | 1989-05-09 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Reconstituted basement membrane complex with biological activity |
| US4861627A (en) * | 1987-05-01 | 1989-08-29 | Massachusetts Institute Of Technology | Preparation of multiwall polymeric microcapsules |
| US5019646A (en) | 1987-08-25 | 1991-05-28 | Regents Of The University Of Minnesota | Polypeptides with fibronectin activity |
| US5843156A (en) | 1988-08-24 | 1998-12-01 | Endoluminal Therapeutics, Inc. | Local polymeric gel cellular therapy |
| JP2528602B2 (ja) * | 1989-12-04 | 1996-08-28 | ケンゼー・ナッシュ・コーポレーション | 開口部を封止するためのプラグ装置 |
| US5180375A (en) * | 1991-05-02 | 1993-01-19 | Feibus Miriam H | Woven surgical drain and woven surgical sponge |
| US5222974A (en) * | 1991-11-08 | 1993-06-29 | Kensey Nash Corporation | Hemostatic puncture closure system and method of use |
| US5955343A (en) * | 1992-12-28 | 1999-09-21 | Massachusetts Institute Of Technology | Stable macroscopic membranes formed by self-assembly of amphiphilic peptides and uses therefor |
| US5670483A (en) * | 1992-12-28 | 1997-09-23 | Massachusetts Insititute Of Technology | Stable macroscopic membranes formed by self-assembly of amphiphilic peptides and uses therefor |
| US5645565A (en) * | 1995-06-13 | 1997-07-08 | Ethicon Endo-Surgery, Inc. | Surgical plug |
| US5762846A (en) | 1996-12-20 | 1998-06-09 | E. I. Du Pont De Nemours And Company | Dispersion spinning process for polytetrafluoroethylene and related polymers |
| US6368877B1 (en) * | 1997-06-25 | 2002-04-09 | Massachusetts Institute Of Technology | Self-assembling peptide surfaces for cell patterning and interactions |
| US5956343A (en) | 1997-12-23 | 1999-09-21 | Alcatel Usa Sourcing L.P. | Designating a control channel in a telecommunications system |
| US6235340B1 (en) | 1998-04-10 | 2001-05-22 | Massachusetts Institute Of Technology | Biopolymer-resistant coatings |
| WO2000041732A1 (en) * | 1999-01-19 | 2000-07-20 | The Children's Hospital Of Philadelphia | Hydrogel compositions for controlled delivery of virus vectors and methods of use thereof |
| WO2000063079A1 (en) * | 1999-04-15 | 2000-10-26 | Ultracell Medical Technologies Of Connecticut, Inc. | Method for producing surgical sponge device and product thereof |
| US6844324B1 (en) * | 1999-11-12 | 2005-01-18 | Massachusetts Institute Of Technology | Modular peptide mediated intracellular delivery system and uses therefore |
| US6953659B2 (en) * | 2000-07-14 | 2005-10-11 | Massachusetts Institute Of Technology | Direct, externally imposed control of nucleic acids |
| US6953656B2 (en) | 2000-07-14 | 2005-10-11 | Massachusetts Institute Of Technology | Direct, externally imposed control of polypeptides |
| US6846319B2 (en) * | 2000-12-14 | 2005-01-25 | Core Medical, Inc. | Devices for sealing openings through tissue and apparatus and methods for delivering them |
| DE60232308D1 (de) * | 2001-01-31 | 2009-06-25 | Asahi Glass Co Ltd | Verfahren zur herstellung von fluorinverbindungen |
| ATE419333T1 (de) | 2001-02-06 | 2009-01-15 | Massachusetts Inst Technology | Peptidgerüstverkapselung von gewebszellen und verwendungen davon |
| US7449180B2 (en) * | 2001-02-06 | 2008-11-11 | John Kisiday | Macroscopic scaffold containing amphiphilic peptides encapsulating cells |
| EP1402001A4 (en) * | 2001-05-04 | 2006-05-24 | Scripps Research Inst | ANTIMICROBIAL PEPTIDES AND COMPOSITIONS |
| WO2003006043A1 (en) * | 2001-07-10 | 2003-01-23 | Massachusetts Institute Of Technology | Surfactant peptide nanostructures, and uses thereof |
| WO2003052117A2 (en) * | 2001-09-19 | 2003-06-26 | Massachusetts Institute Of Technology | Methods and products related to non-viral transfection |
| WO2003084980A2 (en) | 2002-04-02 | 2003-10-16 | Northwestern University | Peptide amphiphile solutions and self assembled peptide nanofiber networks |
| WO2003096972A2 (en) | 2002-05-13 | 2003-11-27 | Massachusetts Institute Of Technology | Angiogenesis and cardiac tissue engineering with peptide hydrogels and related compositions and methods of use thereof |
| CA2387257C (en) * | 2002-05-23 | 2009-07-28 | Suncor Energy Inc. | Static deaeration conditioner for processing of bitumen froth |
| GB0216286D0 (en) | 2002-07-15 | 2002-08-21 | Univ Leeds | Network |
| JP2005534697A (ja) * | 2002-08-06 | 2005-11-17 | エピックス ファーマシューティカルズ， インコーポレイテッド | ペプチド凝集体 |
| MXPA05008483A (es) | 2003-02-11 | 2006-03-10 | Univ Northwestern | Metodos y materiales para revestimientos de superficie nanocristalinos y union de nanofibras de anfililos peptidicos sobre las mismas. |
| WO2004110964A2 (en) * | 2003-06-16 | 2004-12-23 | Nuevolution A/S | Encoded molecules by translation (emt) |
| US7713923B2 (en) * | 2003-06-25 | 2010-05-11 | Massachusetts Institute Of Technology | Self-assembling peptides incorporating modifications and methods of use thereof |
| DK1636250T3 (en) | 2003-06-25 | 2016-02-22 | Massachusetts Inst Technology | SELF-ORGANIZING PEPTIDES, CONTAINING MODIFICATIONS, AND APPLICATIONS THEREOF |
| US7846891B2 (en) * | 2003-10-17 | 2010-12-07 | Massachusetts Institute Of Technology | Self-assembling peptides for regeneration and repair of neural tissue |
| US7704740B2 (en) | 2003-11-05 | 2010-04-27 | Michigan State University | Nanofibrillar structure and applications including cell and tissue culture |
| ES2380340T3 (es) * | 2003-12-05 | 2012-05-10 | Northwestern University | Anfífilos peptídicos auto-ensamblantes y métodos relacionados para la administración de factores de crecimiento |
| GB0413346D0 (en) | 2004-06-15 | 2004-07-21 | Theryte Ltd | Treating cancer |
| EP4023240A1 (en) | 2004-07-06 | 2022-07-06 | 3D Matrix, Inc. | Purified amphiphilic peptide compositions and uses thereof |
| US7884185B2 (en) * | 2004-07-28 | 2011-02-08 | University Of Delaware | Hydrogels and uses thereof |
| WO2006013552A2 (en) | 2004-08-02 | 2006-02-09 | Ramot At Tel Aviv University Ltd. | Articles of peptide nanostructures and method of forming the same |
| US8039258B2 (en) | 2004-09-28 | 2011-10-18 | Ethicon, Inc. | Tissue-engineering scaffolds containing self-assembled-peptide hydrogels |
| US7399831B2 (en) * | 2004-10-25 | 2008-07-15 | The Brigham And Women's Hospital, Inc. | Targeted delivery of biological factors using self-assembling peptide nanofibers |
| US7429567B2 (en) * | 2005-01-04 | 2008-09-30 | The Brigham And Women's Hospital, Inc. | Sustained delivery of PDGF using self-assembling peptide nanofibers |
| US9162005B2 (en) | 2005-04-25 | 2015-10-20 | Arch Biosurgery, Inc. | Compositions for prevention of adhesions and other barrier applications |
| US9327010B2 (en) * | 2005-04-25 | 2016-05-03 | Massachusetts Institute Of Technology | Compositions and methods for promoting hemostasis and other physiological activities |
| US8420605B2 (en) | 2005-09-07 | 2013-04-16 | The University Of Strathclyde | Hydrogel compositions |
| CN101472620A (zh) | 2006-04-25 | 2009-07-01 | 麻省理工学院 | 用于影响污染物、机体流体或其它实体移动和/或影响其它生理状况的组合物和方法 |
| US20070287741A1 (en) * | 2006-06-13 | 2007-12-13 | Uri Herzberg | Compositions and methods for preventing or reducing postoperative ileus and gastric stasis in mammals |
| US8021570B2 (en) * | 2006-06-13 | 2011-09-20 | Wisconsin Alumni Research Foundation | β-peptide lyotropic liquid crystals and methods of manufacture and use thereof |
| DK2146733T3 (da) * | 2007-03-14 | 2021-01-11 | Arch Biosurgery Inc | Treatment of leaky or damaged tight junctions and enhancing extracellular matrix |
| EP2229960B1 (en) | 2007-12-05 | 2015-04-08 | 3-D Matrix, Ltd. | Wound healing/skin reconstruction material |
| EP2345433B1 (en) | 2008-10-06 | 2017-03-01 | 3-D Matrix, Ltd. | Tissue plug |
| US8512728B2 (en) | 2009-02-21 | 2013-08-20 | Sofradim Production | Method of forming a medical device on biological tissue |
| US20120085262A1 (en) | 2010-08-26 | 2012-04-12 | Freudenberg Forschungsdienste Kg | Production of Highly Concentrated Solutions of Self-Assembling Proteins |
| TW201315479A (zh) | 2011-10-12 | 2013-04-16 | Univ Nat Cheng Kung | 可促進動脈新生之醫藥組成物、及其製備方法與應用 |
| WO2014014613A2 (en) | 2012-06-20 | 2014-01-23 | President And Fellows Of Harvard College | Self-assembling peptides, peptide nanostructures and uses thereof |
| US9120841B2 (en) | 2012-09-28 | 2015-09-01 | Agency For Science, Technology And Research | Amphiphilic linear peptidepeptoid and hydrogel comprising the same |
| CN105658252A (zh) | 2013-08-22 | 2016-06-08 | 阿奇生物外科有限公司 | 用于控制流体移动的可植入网状物 |
-
2007
- 2007-04-25 US US11/740,284 patent/US9162005B2/en active Active
-
2008
- 2008-04-25 EP EP12196176.7A patent/EP2581097B1/en not_active Revoked
- 2008-04-25 HU HUE12196176A patent/HUE034194T2/en unknown
- 2008-04-25 JP JP2010506529A patent/JP5976272B2/ja not_active Expired - Fee Related
- 2008-04-25 PL PL12196176T patent/PL2581097T3/pl unknown
- 2008-04-25 CA CA2722465A patent/CA2722465C/en active Active
- 2008-04-25 EP EP08746940A patent/EP2150268A1/en not_active Ceased
- 2008-04-25 WO PCT/US2008/061622 patent/WO2008134544A1/en not_active Ceased
- 2008-04-25 DK DK12196176.7T patent/DK2581097T3/en active
- 2008-04-25 ES ES12196176.7T patent/ES2639625T3/es active Active
-
2015
- 2015-01-08 JP JP2015002075A patent/JP6113764B2/ja not_active Expired - Fee Related
- 2015-10-16 US US14/885,673 patent/US9789157B2/en active Active
-
2017
- 2017-03-14 JP JP2017048126A patent/JP6441978B2/ja not_active Expired - Fee Related
- 2017-09-26 US US15/716,262 patent/US10682386B2/en not_active Expired - Fee Related
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2015128593A5 (enExample) | ||
| JP2015532283A5 (enExample) | ||
| ES2733129T3 (es) | Un nonapéptido con actividad antitumoral | |
| SG10201909675QA (en) | Peptide vaccines for cancers expressing tumor-associated antigens | |
| EP3533461A3 (en) | Prame derived peptides and immunogenic compositions comprising these | |
| JP2008514586A5 (enExample) | ||
| NZ708247A (en) | Hyaluronic acid based formulations | |
| RU2019126232A (ru) | Пептиды и способы для лечения диабета | |
| AR099900A1 (es) | Rellenos para tejidos blandos con polisacáridos con persistencia mejorada, kit, procedimiento, uso | |
| JP2019513696A5 (enExample) | ||
| RU2016130448A (ru) | Пептидные дендримеры, содержащие фибриноген-связывающие пептиды | |
| JP2021504448A5 (enExample) | ||
| JP2019523260A5 (enExample) | ||
| JP2024169717A (ja) | 新規なシータディフェンシンアナログ | |
| JP2014504601A5 (enExample) | ||
| JP2006523608A5 (enExample) | ||
| JP2019535707A5 (enExample) | ||
| JP2018509395A5 (enExample) | ||
| RU2013113677A (ru) | Визуализирующие апоптоз агенты на основе лантибиотических пептидов | |
| JP2015524808A5 (enExample) | ||
| JP2019520336A5 (enExample) | ||
| RU2018132694A (ru) | Фармацевтическая композиция, включающая рекомбинантный гормон роста человека для лечения дефицита гормона роста | |
| US11510985B2 (en) | Oral composition for delivery of drugs and other substances | |
| ES2590757T3 (es) | Péptidos que se dirigen al receptor activador del factor nuclear kappa B (Rank) y sus aplicaciones | |
| Selektor et al. | Study of tooth rotation on the nitinol archwires |