JP2019535707A5 - - Google Patents
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- Publication number
- JP2019535707A5 JP2019535707A5 JP2019524328A JP2019524328A JP2019535707A5 JP 2019535707 A5 JP2019535707 A5 JP 2019535707A5 JP 2019524328 A JP2019524328 A JP 2019524328A JP 2019524328 A JP2019524328 A JP 2019524328A JP 2019535707 A5 JP2019535707 A5 JP 2019535707A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- composition according
- composition
- arthritis
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000000203 mixture Substances 0.000 claims description 55
- 229920001184 polypeptide Polymers 0.000 claims description 52
- 102000004196 processed proteins & peptides Human genes 0.000 claims description 52
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 52
- 125000003275 alpha amino acid group Chemical group 0.000 claims description 14
- 206010007710 Cartilage injury Diseases 0.000 claims description 13
- 206010003246 arthritis Diseases 0.000 claims description 13
- 210000001612 chondrocyte Anatomy 0.000 claims description 7
- 238000002054 transplantation Methods 0.000 claims description 7
- 150000001413 amino acids Chemical class 0.000 claims description 6
- 238000002347 injection Methods 0.000 claims description 6
- 239000007924 injection Substances 0.000 claims description 6
- 238000001356 surgical procedure Methods 0.000 claims description 4
- 206010071155 Autoimmune arthritis Diseases 0.000 claims description 3
- 206010048873 Traumatic arthritis Diseases 0.000 claims description 3
- 210000001185 bone marrow Anatomy 0.000 claims description 3
- 210000000845 cartilage Anatomy 0.000 claims description 3
- 239000011159 matrix material Substances 0.000 claims description 3
- 201000008482 osteoarthritis Diseases 0.000 claims description 3
- 206010039073 rheumatoid arthritis Diseases 0.000 claims description 3
- 230000000638 stimulation Effects 0.000 claims description 3
- 238000000034 method Methods 0.000 description 29
- 238000012986 modification Methods 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 230000002648 chondrogenic effect Effects 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022193539A JP2023039962A (ja) | 2016-11-14 | 2022-12-02 | 軟骨損傷および関節炎の処置のための方法および組成物 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662421534P | 2016-11-14 | 2016-11-14 | |
| US62/421,534 | 2016-11-14 | ||
| US201762560301P | 2017-09-19 | 2017-09-19 | |
| US62/560,301 | 2017-09-19 | ||
| PCT/IB2017/057081 WO2018087727A1 (en) | 2016-11-14 | 2017-11-13 | Methods and compositions for treatment of cartilage damage and arthritis |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022193539A Division JP2023039962A (ja) | 2016-11-14 | 2022-12-02 | 軟骨損傷および関節炎の処置のための方法および組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019535707A JP2019535707A (ja) | 2019-12-12 |
| JP2019535707A5 true JP2019535707A5 (enExample) | 2020-12-24 |
Family
ID=60629753
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019524328A Withdrawn JP2019535707A (ja) | 2016-11-14 | 2017-11-13 | 軟骨損傷および関節炎の処置のための方法および組成物 |
| JP2022193539A Pending JP2023039962A (ja) | 2016-11-14 | 2022-12-02 | 軟骨損傷および関節炎の処置のための方法および組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022193539A Pending JP2023039962A (ja) | 2016-11-14 | 2022-12-02 | 軟骨損傷および関節炎の処置のための方法および組成物 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US11351223B2 (enExample) |
| EP (1) | EP3538127A1 (enExample) |
| JP (2) | JP2019535707A (enExample) |
| KR (2) | KR20190084287A (enExample) |
| CN (2) | CN109963579A (enExample) |
| AU (2) | AU2017357785A1 (enExample) |
| CA (1) | CA3043667A1 (enExample) |
| IL (1) | IL266361B2 (enExample) |
| MX (2) | MX2019005621A (enExample) |
| WO (1) | WO2018087727A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117355323A (zh) | 2021-05-24 | 2024-01-05 | 诺华股份有限公司 | 用于治疗骨关节炎的方法 |
| TW202306970A (zh) | 2021-05-24 | 2023-02-16 | 瑞士商諾華公司 | 用於治療骨關節炎之方法 |
| EP4430395A1 (en) * | 2021-11-10 | 2024-09-18 | Novartis AG | Methods for determining the biological activity of angptl polypeptides |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1490483B1 (en) | 2001-04-19 | 2015-06-03 | The Scripps Research Institute | In vivo incorporation of unnatural amino acids |
| DK1578949T3 (da) | 2002-10-16 | 2009-07-27 | Scripps Research Inst | Stedspecifik optagelse af keto-aminnosyrer hos proteiner |
| KR20050073559A (ko) | 2002-10-16 | 2005-07-14 | 더 스크립스 리서치 인스티튜트 | 당단백질 합성 |
| CN103289960B (zh) | 2003-04-17 | 2017-04-26 | 斯克利普斯研究院 | 扩展真核生物遗传密码 |
| WO2005007624A2 (en) | 2003-07-07 | 2005-01-27 | The Scripps Research Institute | Compositions of orthogonal glutamyl-trna and aminoacyl trna synthetase pairs and uses thereof |
| WO2005007870A2 (en) | 2003-07-07 | 2005-01-27 | The Scripps Research Institute | COMPOSITIONS OF ORTHOGONAL LEUCYL-tRNA AND AMINOACYL-tRNA SYNTHETASE PAIRS AND USES THEREOF |
| DE602004011789T2 (de) | 2003-07-07 | 2009-02-12 | The Scripps Research Institute, La Jolla | Zusammensetzungen der orthogonalen Lysyl-tRNA und Aminoacyl-tRNA Synthetase Paaren und ihre Verwendungen |
| EP1794323B1 (en) | 2004-09-21 | 2014-08-06 | The Scripps Research Institute | In vivo incorporation of alkynyl amino acids into proteins in eubacteria |
| AU2005330514B2 (en) | 2004-10-27 | 2011-05-12 | The Scripps Research Institute | Orthogonal translation components for the in vivo incorporation of unnatural amino acids |
| CA2638763A1 (en) | 2006-03-09 | 2007-09-13 | The Scripps Research Institute | System for the expression of orthogonal translation components in eubacterial host cells |
| EP2118150B1 (en) | 2007-02-14 | 2015-09-23 | Biocompatibles UK Limited | Derivatisation of biological molecules |
| CN102307902B (zh) * | 2008-12-10 | 2016-02-24 | 埃博灵克斯股份有限公司 | 用于治疗与血管发生相关的疾病和病症的针对血管生成素/Tie系统的氨基酸序列和包括其的多肽 |
| PE20160507A1 (es) * | 2009-07-14 | 2016-05-20 | Scripps Research Inst | Diferenciacion de celulas madre mesenquimales |
| UY32979A (es) * | 2009-10-28 | 2011-02-28 | Abbott Lab | Inmunoglobulinas con dominio variable dual y usos de las mismas |
| AU2013204754C1 (en) * | 2012-05-16 | 2018-10-11 | Takeda Pharmaceutical Company Limited | Nucleophilic Catalysts for Oxime Linkage |
| US9301971B2 (en) * | 2013-03-08 | 2016-04-05 | Novartis Ag | Peptides and compositions for treatment of joint damage |
| UY35368A (es) * | 2013-03-08 | 2014-10-31 | Irm Llc | Péptidos y composiciones para el tratamiento de daño articular |
| WO2014151953A1 (en) * | 2013-03-15 | 2014-09-25 | The California Institute For Biomedical Research | Compounds and methods for inducing chondrogenesis |
| UY36118A (es) * | 2014-05-13 | 2016-01-08 | Novartis Ag | Compuestos y composiciones para inducir condrogénesis |
-
2017
- 2017-11-13 IL IL266361A patent/IL266361B2/en unknown
- 2017-11-13 MX MX2019005621A patent/MX2019005621A/es unknown
- 2017-11-13 CA CA3043667A patent/CA3043667A1/en active Pending
- 2017-11-13 KR KR1020197016715A patent/KR20190084287A/ko not_active Ceased
- 2017-11-13 AU AU2017357785A patent/AU2017357785A1/en not_active Abandoned
- 2017-11-13 KR KR1020247009753A patent/KR20240045351A/ko active Pending
- 2017-11-13 WO PCT/IB2017/057081 patent/WO2018087727A1/en not_active Ceased
- 2017-11-13 CN CN201780068935.5A patent/CN109963579A/zh active Pending
- 2017-11-13 EP EP17811710.7A patent/EP3538127A1/en active Pending
- 2017-11-13 CN CN202311759624.7A patent/CN117860868A/zh active Pending
- 2017-11-13 JP JP2019524328A patent/JP2019535707A/ja not_active Withdrawn
- 2017-11-13 US US16/349,435 patent/US11351223B2/en active Active
-
2019
- 2019-05-14 MX MX2022011897A patent/MX2022011897A/es unknown
-
2020
- 2020-12-03 AU AU2020281098A patent/AU2020281098B2/en active Active
-
2022
- 2022-05-06 US US17/662,331 patent/US20220331398A1/en not_active Abandoned
- 2022-12-02 JP JP2022193539A patent/JP2023039962A/ja active Pending
-
2025
- 2025-01-04 US US19/009,988 patent/US20250302915A1/en active Pending
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