JP2014533364A5 - - Google Patents
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- JP2014533364A5 JP2014533364A5 JP2014541281A JP2014541281A JP2014533364A5 JP 2014533364 A5 JP2014533364 A5 JP 2014533364A5 JP 2014541281 A JP2014541281 A JP 2014541281A JP 2014541281 A JP2014541281 A JP 2014541281A JP 2014533364 A5 JP2014533364 A5 JP 2014533364A5
- Authority
- JP
- Japan
- Prior art keywords
- binding
- oligonucleotide sequence
- analyte
- binds
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000027455 binding Effects 0.000 claims description 123
- 238000009739 binding Methods 0.000 claims description 123
- 108091034117 Oligonucleotide Proteins 0.000 claims description 101
- 239000003153 chemical reaction reagent Substances 0.000 claims description 75
- 239000012491 analyte Substances 0.000 claims description 56
- 239000003795 chemical substances by application Substances 0.000 claims description 28
- 239000007787 solid Substances 0.000 claims description 28
- 238000000034 method Methods 0.000 claims description 22
- 230000000295 complement effect Effects 0.000 claims description 17
- 238000000159 protein binding assay Methods 0.000 claims description 15
- 239000000203 mixture Substances 0.000 claims description 11
- 239000002773 nucleotide Substances 0.000 claims description 2
- 125000003729 nucleotide group Chemical group 0.000 claims description 2
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 6
- 229920000642 polymer Polymers 0.000 claims 5
- 238000005406 washing Methods 0.000 claims 2
- 235000010469 Glycine max Nutrition 0.000 claims 1
- 244000068988 Glycine max Species 0.000 claims 1
- 238000002835 absorbance Methods 0.000 claims 1
- 238000000149 argon plasma sintering Methods 0.000 claims 1
- 230000005389 magnetism Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161558537P | 2011-11-11 | 2011-11-11 | |
| US61/558,537 | 2011-11-11 | ||
| PCT/US2012/064263 WO2013070990A1 (en) | 2011-11-11 | 2012-11-09 | Co-binder assisted assay methods |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017231321A Division JP6795733B2 (ja) | 2011-11-11 | 2017-12-01 | コバインダー補助アッセイ法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014533364A JP2014533364A (ja) | 2014-12-11 |
| JP2014533364A5 true JP2014533364A5 (enExample) | 2015-12-17 |
| JP6300727B2 JP6300727B2 (ja) | 2018-03-28 |
Family
ID=48290570
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014541281A Active JP6300727B2 (ja) | 2011-11-11 | 2012-11-09 | コバインダー補助アッセイ法 |
| JP2017231321A Active JP6795733B2 (ja) | 2011-11-11 | 2017-12-01 | コバインダー補助アッセイ法 |
| JP2020079957A Pending JP2020126068A (ja) | 2011-11-11 | 2020-04-30 | コバインダー補助アッセイ法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017231321A Active JP6795733B2 (ja) | 2011-11-11 | 2017-12-01 | コバインダー補助アッセイ法 |
| JP2020079957A Pending JP2020126068A (ja) | 2011-11-11 | 2020-04-30 | コバインダー補助アッセイ法 |
Country Status (6)
| Country | Link |
|---|---|
| US (4) | US9777338B2 (enExample) |
| EP (2) | EP2776833B1 (enExample) |
| JP (3) | JP6300727B2 (enExample) |
| DK (2) | DK3467500T3 (enExample) |
| ES (2) | ES2700792T3 (enExample) |
| WO (1) | WO2013070990A1 (enExample) |
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| US8835358B2 (en) | 2009-12-15 | 2014-09-16 | Cellular Research, Inc. | Digital counting of individual molecules by stochastic attachment of diverse labels |
| DK3467500T3 (da) | 2011-11-11 | 2021-08-16 | Eli N Glezer | Cobinder-understøttede assayfremgangsmåder |
| ES2663234T3 (es) | 2012-02-27 | 2018-04-11 | Cellular Research, Inc | Composiciones y kits para recuento molecular |
| KR20230169418A (ko) | 2013-03-13 | 2023-12-15 | 메소 스케일 테크놀러지즈, 엘엘시 | 개선된 분석 방법 |
| US10114015B2 (en) | 2013-03-13 | 2018-10-30 | Meso Scale Technologies, Llc. | Assay methods |
| EP3480321B8 (en) | 2013-08-28 | 2021-03-10 | Becton, Dickinson and Company | Massively parallel single cell analysis |
| CN119709943A (zh) | 2014-05-15 | 2025-03-28 | 中尺度技术有限责任公司 | 改进的测定方法 |
| ES2836802T3 (es) | 2015-02-27 | 2021-06-28 | Becton Dickinson Co | Códigos de barras moleculares espacialmente direccionables |
| EP4180535A1 (en) | 2015-03-30 | 2023-05-17 | Becton, Dickinson and Company | Methods and compositions for combinatorial barcoding |
| CN107580632B (zh) | 2015-04-23 | 2021-12-28 | 贝克顿迪金森公司 | 用于全转录组扩增的方法和组合物 |
| WO2017044574A1 (en) | 2015-09-11 | 2017-03-16 | Cellular Research, Inc. | Methods and compositions for nucleic acid library normalization |
| JP2018537071A (ja) | 2015-10-01 | 2018-12-20 | ダイナミック バイオセンサーズ ゲーエムベーハー | 固定化された核酸を使用して分子相互作用を検出するための方法 |
| AU2017257597A1 (en) * | 2016-04-26 | 2018-10-04 | Ultivue, Inc. | Super-resolution immunofluorescence with diffraction-limited preview |
| US10301677B2 (en) | 2016-05-25 | 2019-05-28 | Cellular Research, Inc. | Normalization of nucleic acid libraries |
| US10640763B2 (en) | 2016-05-31 | 2020-05-05 | Cellular Research, Inc. | Molecular indexing of internal sequences |
| US10202641B2 (en) | 2016-05-31 | 2019-02-12 | Cellular Research, Inc. | Error correction in amplification of samples |
| US11796535B2 (en) | 2016-09-16 | 2023-10-24 | Plexbio Co., Ltd. | Methods and systems for multiplex assays |
| EP3516400B1 (en) | 2016-09-26 | 2023-08-16 | Becton, Dickinson and Company | Measurement of protein expression using reagents with barcoded oligonucleotide sequences |
| US11319583B2 (en) | 2017-02-01 | 2022-05-03 | Becton, Dickinson And Company | Selective amplification using blocking oligonucleotides |
| CN110719959B (zh) * | 2017-06-05 | 2021-08-06 | 贝克顿迪金森公司 | 针对单细胞的样品索引 |
| WO2019213237A1 (en) | 2018-05-03 | 2019-11-07 | Becton, Dickinson And Company | Molecular barcoding on opposite transcript ends |
| AU2019262048B2 (en) | 2018-05-03 | 2025-09-04 | Becton, Dickinson And Company | High throughput multiomics sample analysis |
| WO2020072380A1 (en) | 2018-10-01 | 2020-04-09 | Cellular Research, Inc. | Determining 5' transcript sequences |
| EP3877520B1 (en) | 2018-11-08 | 2025-03-19 | Becton, Dickson And Company | Whole transcriptome analysis of single cells using random priming |
| US11492660B2 (en) | 2018-12-13 | 2022-11-08 | Becton, Dickinson And Company | Selective extension in single cell whole transcriptome analysis |
| US11661631B2 (en) | 2019-01-23 | 2023-05-30 | Becton, Dickinson And Company | Oligonucleotides associated with antibodies |
| EP3924506A1 (en) | 2019-02-14 | 2021-12-22 | Becton Dickinson and Company | Hybrid targeted and whole transcriptome amplification |
| US11965208B2 (en) | 2019-04-19 | 2024-04-23 | Becton, Dickinson And Company | Methods of associating phenotypical data and single cell sequencing data |
| CN114051534B (zh) | 2019-07-22 | 2025-02-21 | 贝克顿迪金森公司 | 单细胞染色质免疫沉淀测序测定 |
| US11773436B2 (en) | 2019-11-08 | 2023-10-03 | Becton, Dickinson And Company | Using random priming to obtain full-length V(D)J information for immune repertoire sequencing |
| US11649497B2 (en) | 2020-01-13 | 2023-05-16 | Becton, Dickinson And Company | Methods and compositions for quantitation of proteins and RNA |
| US12188010B2 (en) | 2020-01-29 | 2025-01-07 | Becton, Dickinson And Company | Barcoded wells for spatial mapping of single cells through sequencing |
| EP4111168A1 (en) | 2020-02-25 | 2023-01-04 | Becton Dickinson and Company | Bi-specific probes to enable the use of single-cell samples as single color compensation control |
| CN115605614A (zh) | 2020-05-14 | 2023-01-13 | 贝克顿迪金森公司（Us） | 用于免疫组库谱分析的引物 |
| EP4158055B1 (en) | 2020-06-02 | 2024-03-27 | Becton, Dickinson and Company | Oligonucleotides and beads for 5 prime gene expression assay |
| US11932901B2 (en) | 2020-07-13 | 2024-03-19 | Becton, Dickinson And Company | Target enrichment using nucleic acid probes for scRNAseq |
| US11493514B2 (en) | 2020-07-20 | 2022-11-08 | United Arab Emirates University | Method and system for virus and protein-antibody interactions detection and monitoring based on optical light intensity and electrical parameters |
| US11619589B2 (en) | 2020-07-20 | 2023-04-04 | United Arab Emirates University | Method and system for detection, quantification and/or identification of an analyte in a specimen based on electrical and/or optical response to an electric field |
| US12391940B2 (en) | 2020-07-31 | 2025-08-19 | Becton, Dickinson And Company | Single cell assay for transposase-accessible chromatin |
| US11739443B2 (en) | 2020-11-20 | 2023-08-29 | Becton, Dickinson And Company | Profiling of highly expressed and lowly expressed proteins |
| CN116685850A (zh) | 2020-12-15 | 2023-09-01 | 贝克顿迪金森公司 | 单细胞分泌组分析 |
| WO2023080137A1 (ja) * | 2021-11-04 | 2023-05-11 | 凸版印刷株式会社 | 標的物質の検出方法 |
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| US5238808A (en) | 1984-10-31 | 1993-08-24 | Igen, Inc. | Luminescent metal chelate labels and means for detection |
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| DK3467500T3 (da) | 2011-11-11 | 2021-08-16 | Eli N Glezer | Cobinder-understøttede assayfremgangsmåder |
-
2012
- 2012-11-09 DK DK18192525.6T patent/DK3467500T3/da active
- 2012-11-09 ES ES12848432T patent/ES2700792T3/es active Active
- 2012-11-09 DK DK12848432.6T patent/DK2776833T3/da active
- 2012-11-09 EP EP12848432.6A patent/EP2776833B1/en active Active
- 2012-11-09 ES ES18192525T patent/ES2884100T3/es active Active
- 2012-11-09 US US14/357,653 patent/US9777338B2/en active Active
- 2012-11-09 WO PCT/US2012/064263 patent/WO2013070990A1/en not_active Ceased
- 2012-11-09 EP EP18192525.6A patent/EP3467500B1/en active Active
- 2012-11-09 JP JP2014541281A patent/JP6300727B2/ja active Active
-
2017
- 2017-09-06 US US15/696,953 patent/US11242570B2/en active Active
- 2017-12-01 JP JP2017231321A patent/JP6795733B2/ja active Active
-
2020
- 2020-04-30 JP JP2020079957A patent/JP2020126068A/ja active Pending
-
2021
- 2021-10-19 US US17/504,937 patent/US12359264B2/en active Active
-
2025
- 2025-07-02 US US19/258,110 patent/US20250327141A1/en active Pending
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