JP2014533364A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2014533364A5 JP2014533364A5 JP2014541281A JP2014541281A JP2014533364A5 JP 2014533364 A5 JP2014533364 A5 JP 2014533364A5 JP 2014541281 A JP2014541281 A JP 2014541281A JP 2014541281 A JP2014541281 A JP 2014541281A JP 2014533364 A5 JP2014533364 A5 JP 2014533364A5
- Authority
- JP
- Japan
- Prior art keywords
- binding
- oligonucleotide sequence
- analyte
- binds
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000027455 binding Effects 0.000 claims description 123
- 238000009739 binding Methods 0.000 claims description 123
- 108091034117 Oligonucleotide Proteins 0.000 claims description 101
- 239000003153 chemical reaction reagent Substances 0.000 claims description 75
- 239000012491 analyte Substances 0.000 claims description 56
- 239000003795 chemical substances by application Substances 0.000 claims description 28
- 239000007787 solid Substances 0.000 claims description 28
- 238000000034 method Methods 0.000 claims description 22
- 230000000295 complement effect Effects 0.000 claims description 17
- 238000000159 protein binding assay Methods 0.000 claims description 15
- 239000000203 mixture Substances 0.000 claims description 11
- 239000002773 nucleotide Substances 0.000 claims description 2
- 125000003729 nucleotide group Chemical group 0.000 claims description 2
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 6
- 229920000642 polymer Polymers 0.000 claims 5
- 238000005406 washing Methods 0.000 claims 2
- 235000010469 Glycine max Nutrition 0.000 claims 1
- 244000068988 Glycine max Species 0.000 claims 1
- 238000002835 absorbance Methods 0.000 claims 1
- 238000000149 argon plasma sintering Methods 0.000 claims 1
- 230000005389 magnetism Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161558537P | 2011-11-11 | 2011-11-11 | |
| US61/558,537 | 2011-11-11 | ||
| PCT/US2012/064263 WO2013070990A1 (en) | 2011-11-11 | 2012-11-09 | Co-binder assisted assay methods |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017231321A Division JP6795733B2 (ja) | 2011-11-11 | 2017-12-01 | コバインダー補助アッセイ法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014533364A JP2014533364A (ja) | 2014-12-11 |
| JP2014533364A5 true JP2014533364A5 (enExample) | 2015-12-17 |
| JP6300727B2 JP6300727B2 (ja) | 2018-03-28 |
Family
ID=48290570
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014541281A Active JP6300727B2 (ja) | 2011-11-11 | 2012-11-09 | コバインダー補助アッセイ法 |
| JP2017231321A Active JP6795733B2 (ja) | 2011-11-11 | 2017-12-01 | コバインダー補助アッセイ法 |
| JP2020079957A Pending JP2020126068A (ja) | 2011-11-11 | 2020-04-30 | コバインダー補助アッセイ法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017231321A Active JP6795733B2 (ja) | 2011-11-11 | 2017-12-01 | コバインダー補助アッセイ法 |
| JP2020079957A Pending JP2020126068A (ja) | 2011-11-11 | 2020-04-30 | コバインダー補助アッセイ法 |
Country Status (6)
| Country | Link |
|---|---|
| US (4) | US9777338B2 (enExample) |
| EP (2) | EP2776833B1 (enExample) |
| JP (3) | JP6300727B2 (enExample) |
| DK (2) | DK2776833T3 (enExample) |
| ES (2) | ES2700792T3 (enExample) |
| WO (1) | WO2013070990A1 (enExample) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8835358B2 (en) | 2009-12-15 | 2014-09-16 | Cellular Research, Inc. | Digital counting of individual molecules by stochastic attachment of diverse labels |
| ES2700792T3 (es) | 2011-11-11 | 2019-02-19 | Eli N Glezer | Procedimientos de ensayo asistidos por coagente de unión |
| CA2865575C (en) | 2012-02-27 | 2024-01-16 | Cellular Research, Inc. | Compositions and kits for molecular counting |
| US10114015B2 (en) | 2013-03-13 | 2018-10-30 | Meso Scale Technologies, Llc. | Assay methods |
| AU2014248759B2 (en) | 2013-03-13 | 2020-02-27 | Meso Scale Technologies, Llc. | Improved assay methods |
| CN110964796B (zh) | 2013-08-28 | 2024-04-05 | 贝克顿迪金森公司 | 大规模平行单细胞分析 |
| EP3143401A4 (en) | 2014-05-15 | 2017-10-11 | Meso Scale Technologies, LLC | Improved assay methods |
| EP3262192B1 (en) | 2015-02-27 | 2020-09-16 | Becton, Dickinson and Company | Spatially addressable molecular barcoding |
| WO2016160844A2 (en) | 2015-03-30 | 2016-10-06 | Cellular Research, Inc. | Methods and compositions for combinatorial barcoding |
| WO2016172373A1 (en) | 2015-04-23 | 2016-10-27 | Cellular Research, Inc. | Methods and compositions for whole transcriptome amplification |
| CN108026524A (zh) | 2015-09-11 | 2018-05-11 | 赛卢拉研究公司 | 用于核酸文库标准化的方法和组合物 |
| JP2018537071A (ja) | 2015-10-01 | 2018-12-20 | ダイナミック バイオセンサーズ ゲーエムベーハー | 固定化された核酸を使用して分子相互作用を検出するための方法 |
| AU2017257597A1 (en) * | 2016-04-26 | 2018-10-04 | Ultivue, Inc. | Super-resolution immunofluorescence with diffraction-limited preview |
| US10301677B2 (en) | 2016-05-25 | 2019-05-28 | Cellular Research, Inc. | Normalization of nucleic acid libraries |
| US10202641B2 (en) | 2016-05-31 | 2019-02-12 | Cellular Research, Inc. | Error correction in amplification of samples |
| US10640763B2 (en) | 2016-05-31 | 2020-05-05 | Cellular Research, Inc. | Molecular indexing of internal sequences |
| US11796535B2 (en) | 2016-09-16 | 2023-10-24 | Plexbio Co., Ltd. | Methods and systems for multiplex assays |
| KR102638006B1 (ko) | 2016-09-26 | 2024-02-20 | 셀룰러 리서치, 인크. | 바코딩된 올리고뉴클레오티드 서열을 갖는 시약을 이용한 단백질 발현의 측정 |
| US11319583B2 (en) | 2017-02-01 | 2022-05-03 | Becton, Dickinson And Company | Selective amplification using blocking oligonucleotides |
| EP4345172A3 (en) | 2017-06-05 | 2024-07-03 | Becton, Dickinson and Company | Sample indexing for single cells |
| EP4545647A3 (en) | 2018-05-03 | 2025-07-09 | Becton, Dickinson and Company | Molecular barcoding on opposite transcript ends |
| AU2019262048B2 (en) | 2018-05-03 | 2025-09-04 | Becton, Dickinson And Company | High throughput multiomics sample analysis |
| CN118853827A (zh) | 2018-10-01 | 2024-10-29 | 贝克顿迪金森公司 | 确定5’转录物序列 |
| CN112969789A (zh) | 2018-11-08 | 2021-06-15 | 贝克顿迪金森公司 | 使用随机引发的单细胞全转录组分析 |
| EP3894552A1 (en) | 2018-12-13 | 2021-10-20 | Becton, Dickinson and Company | Selective extension in single cell whole transcriptome analysis |
| EP3914728B1 (en) | 2019-01-23 | 2023-04-05 | Becton, Dickinson and Company | Oligonucleotides associated with antibodies |
| CN113454234B (zh) | 2019-02-14 | 2025-03-18 | 贝克顿迪金森公司 | 杂合体靶向和全转录物组扩增 |
| WO2020214642A1 (en) | 2019-04-19 | 2020-10-22 | Becton, Dickinson And Company | Methods of associating phenotypical data and single cell sequencing data |
| EP4004231B1 (en) | 2019-07-22 | 2025-11-12 | Becton, Dickinson and Company | Single cell chromatin immunoprecipitation sequencing assay |
| CN114729350A (zh) | 2019-11-08 | 2022-07-08 | 贝克顿迪金森公司 | 使用随机引发获得用于免疫组库测序的全长v(d)j信息 |
| US11649497B2 (en) | 2020-01-13 | 2023-05-16 | Becton, Dickinson And Company | Methods and compositions for quantitation of proteins and RNA |
| EP4097228B1 (en) | 2020-01-29 | 2024-08-14 | Becton, Dickinson and Company | Barcoded wells for spatial mapping of single cells through sequencing |
| WO2021173719A1 (en) | 2020-02-25 | 2021-09-02 | Becton, Dickinson And Company | Bi-specific probes to enable the use of single-cell samples as single color compensation control |
| EP4150118A1 (en) | 2020-05-14 | 2023-03-22 | Becton Dickinson and Company | Primers for immune repertoire profiling |
| EP4407030B1 (en) | 2020-06-02 | 2025-12-17 | Becton, Dickinson and Company | Oligonucleotides and beads for 5 prime gene expression assay |
| US11932901B2 (en) | 2020-07-13 | 2024-03-19 | Becton, Dickinson And Company | Target enrichment using nucleic acid probes for scRNAseq |
| US11619589B2 (en) | 2020-07-20 | 2023-04-04 | United Arab Emirates University | Method and system for detection, quantification and/or identification of an analyte in a specimen based on electrical and/or optical response to an electric field |
| US11493514B2 (en) | 2020-07-20 | 2022-11-08 | United Arab Emirates University | Method and system for virus and protein-antibody interactions detection and monitoring based on optical light intensity and electrical parameters |
| CN116194589A (zh) | 2020-07-31 | 2023-05-30 | 贝克顿迪金森公司 | 用于转座酶可及染色质的单细胞测定 |
| WO2022109343A1 (en) | 2020-11-20 | 2022-05-27 | Becton, Dickinson And Company | Profiling of highly expressed and lowly expressed proteins |
| US12392771B2 (en) | 2020-12-15 | 2025-08-19 | Becton, Dickinson And Company | Single cell secretome analysis |
| JPWO2023080137A1 (enExample) * | 2021-11-04 | 2023-05-11 |
Family Cites Families (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5310687A (en) | 1984-10-31 | 1994-05-10 | Igen, Inc. | Luminescent metal chelate labels and means for detection |
| US5238808A (en) | 1984-10-31 | 1993-08-24 | Igen, Inc. | Luminescent metal chelate labels and means for detection |
| US6165729A (en) | 1986-04-30 | 2000-12-26 | Hyperion Catalysis International, Inc. | Electrochemiluminescent reaction utilizing amine-derived reductant |
| US5591581A (en) | 1986-04-30 | 1997-01-07 | Igen, Inc. | Electrochemiluminescent rhenium moieties and methods for their use |
| US5147806A (en) | 1988-04-29 | 1992-09-15 | Igen, Inc. | Method and apparatus for conducting electrochemiluminescence measurements |
| US5308754A (en) | 1988-03-21 | 1994-05-03 | Kankare Jouko J | Electrogenerated luminescence in solution |
| US5093268A (en) | 1988-04-28 | 1992-03-03 | Igen, Inc. | Apparatus for conducting a plurality of simultaneous measurements of electrochemiluminescent phenomena |
| US5705402A (en) | 1988-11-03 | 1998-01-06 | Igen International, Inc. | Method and apparatus for magnetic microparticulate based luminescence assay including plurality of magnets |
| US5324457A (en) | 1989-10-02 | 1994-06-28 | Board Of Regents, The University Of Tx System | Devices and methods for generating electrogenerated chemiluminescence |
| US5200314A (en) | 1990-03-23 | 1993-04-06 | Chiron Corporation | Polynucleotide capture assay employing in vitro amplification |
| US5776672A (en) | 1990-09-28 | 1998-07-07 | Kabushiki Kaisha Toshiba | Gene detection method |
| JPH0534345A (ja) | 1991-02-19 | 1993-02-09 | Tdk Corp | 化学発光を利用する抗原・抗体の測定方法 |
| US6872816B1 (en) | 1996-01-24 | 2005-03-29 | Third Wave Technologies, Inc. | Nucleic acid detection kits |
| ZA929351B (en) | 1991-12-11 | 1993-06-04 | Igen Inc | Electrochemiluminescent label for DNA assays. |
| CA2172248C (en) * | 1993-09-22 | 2003-12-30 | John Kenten | Self-sustained sequence replication electrochemiluminescent nucleic acid assay |
| US5786141A (en) | 1994-08-26 | 1998-07-28 | Bard; Allen J. | Electrogenerated chemiluminescence labels for analysis and/or referencing |
| US5866434A (en) | 1994-12-08 | 1999-02-02 | Meso Scale Technology | Graphitic nanotubes in luminescence assays |
| US5641623A (en) | 1995-01-04 | 1997-06-24 | Martin; Mark T. | Electrochemiluminescence assay |
| US5643713A (en) | 1995-06-07 | 1997-07-01 | Liang; Pam | Electrochemiluminescent monitoring of compounds |
| CN1192097C (zh) | 1995-03-10 | 2005-03-09 | 梅索磅秤技术有限公司 | 多阵列、多特异性的电化学发光检验 |
| US6673533B1 (en) * | 1995-03-10 | 2004-01-06 | Meso Scale Technologies, Llc. | Multi-array multi-specific electrochemiluminescence testing |
| US6207369B1 (en) | 1995-03-10 | 2001-03-27 | Meso Scale Technologies, Llc | Multi-array, multi-specific electrochemiluminescence testing |
| US5679519A (en) | 1995-05-09 | 1997-10-21 | Oprandy; John J. | Multi-label complex for enhanced sensitivity in electrochemiluminescence assay |
| US6319670B1 (en) | 1995-05-09 | 2001-11-20 | Meso Scale Technology Llp | Methods and apparatus for improved luminescence assays using microparticles |
| US5589136A (en) | 1995-06-20 | 1996-12-31 | Regents Of The University Of California | Silicon-based sleeve devices for chemical reactions |
| EP0852004B1 (en) | 1995-10-11 | 2011-01-19 | Luminex Corporation | Multiplexed analysis of clinical specimens |
| GB9606850D0 (en) | 1996-04-01 | 1996-06-05 | Univ Liverpool | An assay system and novel labelled compounds for use therwith |
| JP2001523111A (ja) * | 1997-05-05 | 2001-11-20 | サード ウェーブ テクノロジーズ，インコーポレーテッド | 構造体架橋オリゴヌクレオチドを使用した標的依存型反応 |
| US7314711B2 (en) * | 1997-05-23 | 2008-01-01 | Bioveris Corporation | Assays employing electrochemiluminescent labels and electrochemiluminescence quenchers |
| FR2764381A1 (fr) | 1997-06-09 | 1998-12-11 | Univ De Neuchatel | Detecteur electrochimioluminescent |
| US6413783B1 (en) | 1997-09-18 | 2002-07-02 | Meso Scale Technologies, Llc | Assay sonication apparatus and methodology |
| US6200531B1 (en) | 1998-05-11 | 2001-03-13 | Igen International, Inc. | Apparatus for carrying out electrochemiluminescence test measurements |
| US8063190B2 (en) | 1998-06-02 | 2011-11-22 | Tom Robin Caine Boyde | Nucleic acid-linked conjugates and methods for making and using them |
| EP0962773A1 (en) | 1998-06-03 | 1999-12-08 | Mark Howard Jones | Electrochemical based assay processes instrument and labels |
| GB9815042D0 (en) | 1998-07-10 | 1998-09-09 | Imperial College | Detector |
| US6214552B1 (en) | 1998-09-17 | 2001-04-10 | Igen International, Inc. | Assays for measuring nucleic acid damaging activities |
| US6136268A (en) | 1999-08-17 | 2000-10-24 | Orion Diagnostica | Method for luminescence measurements |
| US6800608B2 (en) * | 2001-06-22 | 2004-10-05 | Beckman Coulter, Inc. | Homogeneous assay of vancomycin using a stable particle-vancomycin conjugate, a novel rate enhancer, and a novel dose response modulator |
| AU2003287527A1 (en) | 2002-12-18 | 2004-07-29 | Aclara Biosciences, Inc. | Single cell analysis of membrane molecules |
| CN101410530B (zh) * | 2003-04-18 | 2013-03-27 | 贝克顿·迪金森公司 | 免疫-扩增 |
| US7195875B2 (en) * | 2003-04-18 | 2007-03-27 | Beckman Coulter, Inc. | Oligonucleotide pairs for multiplexed binding assays |
| US20040248103A1 (en) * | 2003-06-04 | 2004-12-09 | Feaver William John | Proximity-mediated rolling circle amplification |
| WO2005059509A2 (en) | 2003-12-12 | 2005-06-30 | Saint Louis University | Biosensors for detecting macromolecules and other analytes |
| US8313903B2 (en) * | 2006-03-31 | 2012-11-20 | The Trustees Of Columbia University In The City Of New York | Binary DNA probe for fluorescent analysis of nucleic acids |
| EP2010475A2 (en) * | 2006-04-27 | 2009-01-07 | Intezyne Technologies Incorporated | Heterofunctional poly(ethylene glycol) containing acid-labile amino protecting groups and uses thereof |
| JP5329038B2 (ja) * | 2006-12-21 | 2013-10-30 | 宇部日東化成株式会社 | 半導体装置及び半導体装置の製造方法 |
| ES2367232T3 (es) | 2007-11-21 | 2011-10-31 | Erasmus University Medical Center Rotterdam | Sondas de fret mejoradas y su uso. |
| JP5435878B2 (ja) * | 2008-02-12 | 2014-03-05 | 富士フイルム株式会社 | 断片化抗体を標識物質に固定した標識粒子 |
| EP2703816B1 (en) | 2008-11-21 | 2016-10-05 | Saint Louis University | Biosensor for detecting multiple epitopes on a target |
| US20100261292A1 (en) | 2009-04-10 | 2010-10-14 | Meso Scale Technologies, Llc | Methods for Conducting Assays |
| JP5954876B2 (ja) * | 2009-10-13 | 2016-07-20 | ナノストリング テクノロジーズ， インコーポレイテッド | ナノレポーターによるタンパク質の検出 |
| WO2011143583A1 (en) * | 2010-05-13 | 2011-11-17 | Illumina, Inc. | Binding assays for markers |
| ES2700792T3 (es) | 2011-11-11 | 2019-02-19 | Eli N Glezer | Procedimientos de ensayo asistidos por coagente de unión |
-
2012
- 2012-11-09 ES ES12848432T patent/ES2700792T3/es active Active
- 2012-11-09 US US14/357,653 patent/US9777338B2/en active Active
- 2012-11-09 EP EP12848432.6A patent/EP2776833B1/en active Active
- 2012-11-09 EP EP18192525.6A patent/EP3467500B1/en active Active
- 2012-11-09 DK DK12848432.6T patent/DK2776833T3/da active
- 2012-11-09 DK DK18192525.6T patent/DK3467500T3/da active
- 2012-11-09 WO PCT/US2012/064263 patent/WO2013070990A1/en not_active Ceased
- 2012-11-09 JP JP2014541281A patent/JP6300727B2/ja active Active
- 2012-11-09 ES ES18192525T patent/ES2884100T3/es active Active
-
2017
- 2017-09-06 US US15/696,953 patent/US11242570B2/en active Active
- 2017-12-01 JP JP2017231321A patent/JP6795733B2/ja active Active
-
2020
- 2020-04-30 JP JP2020079957A patent/JP2020126068A/ja active Pending
-
2021
- 2021-10-19 US US17/504,937 patent/US12359264B2/en active Active
-
2025
- 2025-07-02 US US19/258,110 patent/US20250327141A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2014533364A5 (enExample) | ||
| JP6795733B2 (ja) | コバインダー補助アッセイ法 | |
| Wang et al. | Novel label-free and high-throughput microchip electrophoresis platform for multiplex antibiotic residues detection based on aptamer probes and target catalyzed hairpin assembly for signal amplification | |
| Shamsi et al. | Electrochemiluminescence on digital microfluidics for microRNA analysis | |
| ATE489482T1 (de) | Verfahren zur herstellung von hybridsubstraten mit dna und antikörpern sowie verwendungen davon | |
| ATE414096T1 (de) | Verfahren zum nachweis und zur quantifizierung von analyten in komplexen mischungen | |
| EP1948822A4 (en) | NUCLEIC ACID ENZYMES WITH SEVERAL INGREDIENTS AND METHOD OF USE THEREOF | |
| Xu et al. | Homogeneous bioluminescence detection of biomolecules using target-triggered hybridization chain reaction-mediated ligation without luciferase label | |
| JP2016512429A5 (enExample) | ||
| WO2007115242A3 (en) | Binary probes for fluorescent analysis of nucleic acids | |
| ATE466107T1 (de) | Verfahren und zusammensetzungen zum nachweis von nukleinsäuren in einer biologischen probe | |
| Jung et al. | Highly tunable aptasensing microarrays with graphene oxide multilayers | |
| JP7051680B2 (ja) | 遺伝子検査チップ、その検査方法、製造方法およびマイクロフルイディクスチップシステム | |
| ATE533052T1 (de) | Reagenzien, kits und verfahren zum nachweis biologischer moleküle mittels energieübertragung von einem aktivierten chemilumineszenzsubstrat auf einen energieakzeptorfarbstoff | |
| JP2010539940A5 (enExample) | ||
| JP2012509063A5 (enExample) | ||
| JP2012509062A5 (enExample) | ||
| CN104165999B (zh) | 基于邻位触击效应的均相化学发光免疫分析方法 | |
| ATE545030T1 (de) | Testverfahren für nukleinsäurebindendes protein auf biochipbasis | |
| WO2008068636A3 (en) | Blocking agents comprising non-natural nucleic acids and detection methods using such blocking agents | |
| JP2017529062A (ja) | ２個のリガンドと１個のレセプタとからなる高親和性錯体の特定方法と該方法を実行する装置及び該方法に用いられる自己集合型ケミカルライブラリ | |
| FI4399331T3 (fi) | Menetelmä sense- ja antisense-juosteiden havaitsemiseksi oligonukleotididupleksissa | |
| JPWO2009022683A1 (ja) | 標的物質の検出方法 | |
| CN110691853B (zh) | 利用单一荧光通道聚合酶链反应设备的多重核酸检测方法 | |
| DE502005010036D1 (de) | Verfahren zur geno- und pathotypisierung von pseudomonas aeruginosa |