JP6300727B2 - コバインダー補助アッセイ法 - Google Patents
コバインダー補助アッセイ法 Download PDFInfo
- Publication number
- JP6300727B2 JP6300727B2 JP2014541281A JP2014541281A JP6300727B2 JP 6300727 B2 JP6300727 B2 JP 6300727B2 JP 2014541281 A JP2014541281 A JP 2014541281A JP 2014541281 A JP2014541281 A JP 2014541281A JP 6300727 B2 JP6300727 B2 JP 6300727B2
- Authority
- JP
- Japan
- Prior art keywords
- binding
- oligonucleotide sequence
- analyte
- oligonucleotide
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
- G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161558537P | 2011-11-11 | 2011-11-11 | |
| US61/558,537 | 2011-11-11 | ||
| PCT/US2012/064263 WO2013070990A1 (en) | 2011-11-11 | 2012-11-09 | Co-binder assisted assay methods |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017231321A Division JP6795733B2 (ja) | 2011-11-11 | 2017-12-01 | コバインダー補助アッセイ法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014533364A JP2014533364A (ja) | 2014-12-11 |
| JP2014533364A5 JP2014533364A5 (enExample) | 2015-12-17 |
| JP6300727B2 true JP6300727B2 (ja) | 2018-03-28 |
Family
ID=48290570
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014541281A Active JP6300727B2 (ja) | 2011-11-11 | 2012-11-09 | コバインダー補助アッセイ法 |
| JP2017231321A Active JP6795733B2 (ja) | 2011-11-11 | 2017-12-01 | コバインダー補助アッセイ法 |
| JP2020079957A Pending JP2020126068A (ja) | 2011-11-11 | 2020-04-30 | コバインダー補助アッセイ法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017231321A Active JP6795733B2 (ja) | 2011-11-11 | 2017-12-01 | コバインダー補助アッセイ法 |
| JP2020079957A Pending JP2020126068A (ja) | 2011-11-11 | 2020-04-30 | コバインダー補助アッセイ法 |
Country Status (6)
| Country | Link |
|---|---|
| US (4) | US9777338B2 (enExample) |
| EP (2) | EP3467500B1 (enExample) |
| JP (3) | JP6300727B2 (enExample) |
| DK (2) | DK3467500T3 (enExample) |
| ES (2) | ES2700792T3 (enExample) |
| WO (1) | WO2013070990A1 (enExample) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8835358B2 (en) | 2009-12-15 | 2014-09-16 | Cellular Research, Inc. | Digital counting of individual molecules by stochastic attachment of diverse labels |
| US9777338B2 (en) | 2011-11-11 | 2017-10-03 | Meso Scale Technologies, Llc. | Co-binder assisted assay methods |
| HK1206069A1 (en) | 2012-02-27 | 2015-12-31 | Cellular Research, Inc. | Compositions and kits for molecular counting |
| US9618510B2 (en) | 2013-03-13 | 2017-04-11 | Meso Scale Technologies, Llc. | Assay methods |
| US10114015B2 (en) | 2013-03-13 | 2018-10-30 | Meso Scale Technologies, Llc. | Assay methods |
| AU2014312208B2 (en) | 2013-08-28 | 2019-07-25 | Becton, Dickinson And Company | Massively parallel single cell analysis |
| KR102497054B1 (ko) | 2014-05-15 | 2023-02-06 | 메소 스케일 테크놀러지즈, 엘엘시 | 개선된 분석 방법 |
| CN107208158B (zh) | 2015-02-27 | 2022-01-28 | 贝克顿迪金森公司 | 空间上可寻址的分子条形编码 |
| EP3277843A2 (en) | 2015-03-30 | 2018-02-07 | Cellular Research, Inc. | Methods and compositions for combinatorial barcoding |
| WO2016172373A1 (en) | 2015-04-23 | 2016-10-27 | Cellular Research, Inc. | Methods and compositions for whole transcriptome amplification |
| ES2745694T3 (es) | 2015-09-11 | 2020-03-03 | Cellular Res Inc | Métodos y composiciones para normalización de biblioteca de ácido nucleico |
| JP2018537071A (ja) * | 2015-10-01 | 2018-12-20 | ダイナミック バイオセンサーズ ゲーエムベーハー | 固定化された核酸を使用して分子相互作用を検出するための方法 |
| US11079388B2 (en) * | 2016-04-26 | 2021-08-03 | Ultivue, Inc. | Super-resolution immunofluorescence with diffraction-limited preview |
| US10301677B2 (en) | 2016-05-25 | 2019-05-28 | Cellular Research, Inc. | Normalization of nucleic acid libraries |
| US10640763B2 (en) | 2016-05-31 | 2020-05-05 | Cellular Research, Inc. | Molecular indexing of internal sequences |
| US10202641B2 (en) | 2016-05-31 | 2019-02-12 | Cellular Research, Inc. | Error correction in amplification of samples |
| EP3513186A4 (en) * | 2016-09-16 | 2020-04-29 | Plexbio Co., Ltd. | METHODS AND SYSTEMS FOR MULTIPLEX TESTS |
| SG11201901733PA (en) | 2016-09-26 | 2019-04-29 | Cellular Res Inc | Measurement of protein expression using reagents with barcoded oligonucleotide sequences |
| US11319583B2 (en) | 2017-02-01 | 2022-05-03 | Becton, Dickinson And Company | Selective amplification using blocking oligonucleotides |
| CA3059559A1 (en) | 2017-06-05 | 2018-12-13 | Becton, Dickinson And Company | Sample indexing for single cells |
| JP7407128B2 (ja) | 2018-05-03 | 2023-12-28 | ベクトン・ディキンソン・アンド・カンパニー | ハイスループットマルチオミクスサンプル解析 |
| CN118910215A (zh) | 2018-05-03 | 2024-11-08 | 贝克顿迪金森公司 | 在相对的转录物末端进行分子条形码化 |
| EP3861134B1 (en) | 2018-10-01 | 2024-09-04 | Becton, Dickinson and Company | Determining 5' transcript sequences |
| CN112969789A (zh) | 2018-11-08 | 2021-06-15 | 贝克顿迪金森公司 | 使用随机引发的单细胞全转录组分析 |
| CN113195717A (zh) | 2018-12-13 | 2021-07-30 | 贝克顿迪金森公司 | 单细胞全转录组分析中的选择性延伸 |
| CN113574178B (zh) | 2019-01-23 | 2024-10-29 | 贝克顿迪金森公司 | 与抗体关联的寡核苷酸 |
| EP3924506A1 (en) | 2019-02-14 | 2021-12-22 | Becton Dickinson and Company | Hybrid targeted and whole transcriptome amplification |
| US11965208B2 (en) | 2019-04-19 | 2024-04-23 | Becton, Dickinson And Company | Methods of associating phenotypical data and single cell sequencing data |
| WO2021016239A1 (en) | 2019-07-22 | 2021-01-28 | Becton, Dickinson And Company | Single cell chromatin immunoprecipitation sequencing assay |
| ES2987640T3 (es) | 2019-11-08 | 2024-11-15 | Becton Dickinson Co | Uso de cebado aleatorio para obtener información de V(D)J de longitud completa para la secuenciación del repertorio inmunitario |
| CN115244184A (zh) | 2020-01-13 | 2022-10-25 | 贝克顿迪金森公司 | 用于定量蛋白和rna的方法和组合物 |
| EP4097228B1 (en) | 2020-01-29 | 2024-08-14 | Becton, Dickinson and Company | Barcoded wells for spatial mapping of single cells through sequencing |
| CN115151810A (zh) | 2020-02-25 | 2022-10-04 | 贝克顿迪金森公司 | 实现使用单细胞样品作为单色补偿对照的双特异性探针 |
| EP4150118A1 (en) | 2020-05-14 | 2023-03-22 | Becton Dickinson and Company | Primers for immune repertoire profiling |
| CN115803445A (zh) | 2020-06-02 | 2023-03-14 | 贝克顿迪金森公司 | 用于5撇基因表达测定的寡核苷酸和珠 |
| US11932901B2 (en) | 2020-07-13 | 2024-03-19 | Becton, Dickinson And Company | Target enrichment using nucleic acid probes for scRNAseq |
| WO2022018622A1 (en) | 2020-07-20 | 2022-01-27 | United Arab Emirates University | Method and system for virus and protein-antibody interactions detection and monitoring based on optical light intensity and electrical parameters |
| US11619589B2 (en) | 2020-07-20 | 2023-04-04 | United Arab Emirates University | Method and system for detection, quantification and/or identification of an analyte in a specimen based on electrical and/or optical response to an electric field |
| CN116194589A (zh) | 2020-07-31 | 2023-05-30 | 贝克顿迪金森公司 | 用于转座酶可及染色质的单细胞测定 |
| WO2022109343A1 (en) | 2020-11-20 | 2022-05-27 | Becton, Dickinson And Company | Profiling of highly expressed and lowly expressed proteins |
| WO2022132206A1 (en) | 2020-12-15 | 2022-06-23 | Becton, Dickinson And Company | Single cell secretome analysis |
| WO2023080137A1 (ja) * | 2021-11-04 | 2023-05-11 | 凸版印刷株式会社 | 標的物質の検出方法 |
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-
2012
- 2012-11-09 US US14/357,653 patent/US9777338B2/en active Active
- 2012-11-09 WO PCT/US2012/064263 patent/WO2013070990A1/en not_active Ceased
- 2012-11-09 JP JP2014541281A patent/JP6300727B2/ja active Active
- 2012-11-09 DK DK18192525.6T patent/DK3467500T3/da active
- 2012-11-09 ES ES12848432T patent/ES2700792T3/es active Active
- 2012-11-09 DK DK12848432.6T patent/DK2776833T3/da active
- 2012-11-09 ES ES18192525T patent/ES2884100T3/es active Active
- 2012-11-09 EP EP18192525.6A patent/EP3467500B1/en active Active
- 2012-11-09 EP EP12848432.6A patent/EP2776833B1/en active Active
-
2017
- 2017-09-06 US US15/696,953 patent/US11242570B2/en active Active
- 2017-12-01 JP JP2017231321A patent/JP6795733B2/ja active Active
-
2020
- 2020-04-30 JP JP2020079957A patent/JP2020126068A/ja active Pending
-
2021
- 2021-10-19 US US17/504,937 patent/US12359264B2/en active Active
-
2025
- 2025-07-02 US US19/258,110 patent/US20250327141A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP2776833A4 (en) | 2015-12-02 |
| EP2776833A1 (en) | 2014-09-17 |
| JP2014533364A (ja) | 2014-12-11 |
| US20220033918A1 (en) | 2022-02-03 |
| WO2013070990A1 (en) | 2013-05-16 |
| EP3467500A1 (en) | 2019-04-10 |
| JP2018054629A (ja) | 2018-04-05 |
| ES2884100T3 (es) | 2021-12-10 |
| JP2020126068A (ja) | 2020-08-20 |
| DK2776833T3 (da) | 2019-01-02 |
| DK3467500T3 (da) | 2021-08-16 |
| EP2776833B1 (en) | 2018-09-05 |
| EP3467500B1 (en) | 2021-05-12 |
| US11242570B2 (en) | 2022-02-08 |
| US20250327141A1 (en) | 2025-10-23 |
| US12359264B2 (en) | 2025-07-15 |
| US20170362668A1 (en) | 2017-12-21 |
| US20140315189A1 (en) | 2014-10-23 |
| US9777338B2 (en) | 2017-10-03 |
| ES2700792T3 (es) | 2019-02-19 |
| JP6795733B2 (ja) | 2020-12-02 |
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