JP2014532481A5 - - Google Patents
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- Publication number
- JP2014532481A5 JP2014532481A5 JP2014539116A JP2014539116A JP2014532481A5 JP 2014532481 A5 JP2014532481 A5 JP 2014532481A5 JP 2014539116 A JP2014539116 A JP 2014539116A JP 2014539116 A JP2014539116 A JP 2014539116A JP 2014532481 A5 JP2014532481 A5 JP 2014532481A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- polyoxyethylene
- weight
- polyoxypropylene block
- block copolymer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 51
- 229920001400 block copolymer Polymers 0.000 claims 26
- 229920002503 polyoxyethylene-polyoxypropylene Polymers 0.000 claims 25
- 239000002245 particle Substances 0.000 claims 11
- 125000002947 alkylene group Chemical group 0.000 claims 10
- 239000000919 ceramic Substances 0.000 claims 10
- 229920001577 copolymer Polymers 0.000 claims 10
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical group C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 claims 4
- GOOHAUXETOMSMM-UHFFFAOYSA-N Propylene oxide Chemical group CC1CO1 GOOHAUXETOMSMM-UHFFFAOYSA-N 0.000 claims 4
- 210000000988 bone and bone Anatomy 0.000 claims 3
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims 2
- -1 polyoxyethylene Polymers 0.000 claims 2
- 229920001451 polypropylene glycol Polymers 0.000 claims 2
- 229940030225 antihemorrhagics Drugs 0.000 claims 1
- 239000002874 hemostatic agent Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000002844 melting Methods 0.000 claims 1
- 230000008018 melting Effects 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 238000004806 packaging method and process Methods 0.000 claims 1
- 229920000428 triblock copolymer Polymers 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161553032P | 2011-10-28 | 2011-10-28 | |
| US61/553,032 | 2011-10-28 | ||
| PCT/US2012/062437 WO2013063580A1 (en) | 2011-10-28 | 2012-10-29 | Nonaqueous compositions for bone hemostasis, and methods for their use and manufacture |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014532481A JP2014532481A (ja) | 2014-12-08 |
| JP2014532481A5 true JP2014532481A5 (https=) | 2016-01-28 |
| JP6095675B2 JP6095675B2 (ja) | 2017-03-15 |
Family
ID=48168649
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014539116A Active JP6095675B2 (ja) | 2011-10-28 | 2012-10-29 | 骨止血のための非水性組成物、およびそれらを使用し、製造するための方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US9512277B2 (https=) |
| EP (2) | EP2771040B1 (https=) |
| JP (1) | JP6095675B2 (https=) |
| KR (2) | KR102068118B1 (https=) |
| CN (1) | CN104010669A (https=) |
| AU (1) | AU2012328415B2 (https=) |
| BR (1) | BR112014010192B1 (https=) |
| CA (2) | CA2853732C (https=) |
| ES (2) | ES2961982T3 (https=) |
| HK (1) | HK1201213A1 (https=) |
| MX (1) | MX359402B (https=) |
| WO (2) | WO2013063580A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101712809B1 (ko) * | 2015-03-19 | 2017-03-08 | 주식회사 엠아이텍 | 뼈 지혈용 생체 흡수성 조성물 및 이의 제조 방법 |
| CN105816905B (zh) * | 2016-04-15 | 2020-12-18 | 广州贝奥吉因生物科技有限公司 | 一种具有促愈合功能的可吸收骨蜡及其制备方法 |
| CN106039390A (zh) * | 2016-05-27 | 2016-10-26 | 中国人民解放军第七五医院 | 一种骨蜡组合物及其制备方法 |
| KR101990069B1 (ko) * | 2017-11-28 | 2019-06-18 | ㈜솔시온바이오메디칼 | 뼈 지혈용품 조성물 |
| CN109125791B (zh) * | 2018-09-29 | 2019-08-30 | 广州贝奥吉因生物科技有限公司 | 一种具有促进骨修复功能的可吸收骨蜡及制备方法 |
| KR102220832B1 (ko) | 2018-12-13 | 2021-02-25 | 건양대학교 산학협력단 | 세포 독성이 감소된 생체흡수성 뼈 지혈제의 제조방법 |
| KR102211765B1 (ko) * | 2019-01-15 | 2021-02-03 | 주식회사 테라시온바이오메디칼 | 흡수성 골 지혈재 조성물 및 이를 이용한 골 지혈재 제조방법 |
| CN111714684A (zh) * | 2019-03-19 | 2020-09-29 | 广东博与再生医学有限公司 | 一种骨止血材料及其制备方法 |
| KR102133503B1 (ko) * | 2019-08-19 | 2020-07-13 | 한스바이오메드 주식회사 | 골지혈제용 생체 적합성 조성물, 이를 사용하는 치료 방법, 및 이의 제조 방법 |
| US12285546B2 (en) | 2019-08-27 | 2025-04-29 | Dof Inc. | Animal fat-derived extracellular matrix, and preservation solution of animal fat-derived extracellular matrix |
| CN114404642A (zh) * | 2022-04-01 | 2022-04-29 | 天新福(北京)医疗器材股份有限公司 | 一种可吸收止血骨泥及其制备方法 |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3171072D1 (en) * | 1981-06-25 | 1985-07-25 | Stroetmann M Serapharm | Enriched plasma derivative for promoting wound sealing and wound covering |
| US6054122A (en) * | 1990-11-27 | 2000-04-25 | The American National Red Cross | Supplemented and unsupplemented tissue sealants, methods of their production and use |
| USRE38558E1 (en) | 1991-03-19 | 2004-07-20 | Cytrx Corporation | Polyoxypropylene/polyoxyethylene copolymers with improved biological activity |
| AU6898996A (en) * | 1995-08-21 | 1997-03-12 | Cytrx Corporation | Compositions and methods for growth promotion |
| US6194515B1 (en) * | 1997-10-10 | 2001-02-27 | E. I. Du Pont De Nemours And Company | Polyacetal composition with improved toughness |
| US9616150B2 (en) * | 1999-10-29 | 2017-04-11 | Children's Hospital Los Angeles | Bone hemostasis method and materials |
| US8067032B2 (en) | 2000-12-22 | 2011-11-29 | Baxter International Inc. | Method for preparing submicron particles of antineoplastic agents |
| WO2003072157A1 (en) * | 2002-02-21 | 2003-09-04 | Encelle, Inc. | Immobilized bioactive hydrogel matrices as surface coatings |
| DE10225420A1 (de) * | 2002-06-07 | 2003-12-24 | Sanatis Gmbh | Strontium-Apatit-Zement-Zubereitungen, die daraus gebildeten Zemente und die Verwendung davon |
| US20060258560A1 (en) * | 2002-09-30 | 2006-11-16 | Chunlin Yang | Dry tissue sealant compositions |
| JP5508661B2 (ja) | 2003-02-12 | 2014-06-04 | シンセラ インコーポレイテッド | ランダムおよび非ランダムアルキレンオキシドポリマーアロイ組成物 |
| EP1684819A2 (en) * | 2003-11-20 | 2006-08-02 | Angiotech International Ag | Polymer compositions and methods for their use |
| CA2571656A1 (en) | 2004-06-23 | 2006-01-05 | Angiotech Biomaterials Corporation | Methods and crosslinked polymer compositions for cartilage repair |
| US8603528B2 (en) * | 2004-09-16 | 2013-12-10 | Abyrx, Inc. | Compositions and method for the reduction of post-operative pain |
| NZ563557A (en) * | 2005-07-25 | 2011-04-29 | Orthocon Inc | Compositions and methods for the reduction of post-operative pain |
| CA2646486A1 (en) * | 2006-03-23 | 2007-09-27 | Citagenix Inc. | Reverse phase osteoconductive composition |
| EP2026756B1 (en) | 2006-05-22 | 2020-06-17 | Syncera, Inc. | Resorbable polymer compositions for use in medicine, dentistry, and surgery |
| US8309521B2 (en) * | 2007-06-19 | 2012-11-13 | Zimmer, Inc. | Spacer with a coating thereon for use with an implant device |
| US8815973B2 (en) * | 2007-08-28 | 2014-08-26 | Pioneer Surgical Technology, Inc. | Cement products and methods of making and using the same |
| EP2227212A1 (en) * | 2007-12-07 | 2010-09-15 | BioCure, Inc. | Bone substitute |
| GB0801935D0 (en) * | 2008-02-01 | 2008-03-12 | Apatech Ltd | Porous biomaterial |
| CN102014973A (zh) | 2008-02-29 | 2011-04-13 | 弗罗桑医疗设备公司 | 用于促进止血和/或伤口愈合的装置 |
| US20100233269A1 (en) * | 2009-03-13 | 2010-09-16 | Baxter International, Inc. | Mineralized polymer particles and the method for their production |
| BRPI1014139A2 (pt) * | 2009-06-29 | 2016-04-26 | Bender Analytical Holding Bv | sistema de liberação de fármacos compreendendo polioxazolina e um agente biotivo. |
| AU2011239742B2 (en) | 2010-04-16 | 2014-11-27 | Apatech Limited | Biomaterial |
| WO2014086996A1 (en) * | 2012-12-07 | 2014-06-12 | Baxter International Inc. | Hemostatic foam |
-
2012
- 2012-10-29 WO PCT/US2012/062437 patent/WO2013063580A1/en not_active Ceased
- 2012-10-29 US US13/663,098 patent/US9512277B2/en active Active
- 2012-10-29 WO PCT/US2012/062445 patent/WO2013063585A1/en not_active Ceased
- 2012-10-29 CN CN201280062889.5A patent/CN104010669A/zh active Pending
- 2012-10-29 BR BR112014010192-2A patent/BR112014010192B1/pt not_active IP Right Cessation
- 2012-10-29 HK HK15101786.9A patent/HK1201213A1/xx unknown
- 2012-10-29 MX MX2014005135A patent/MX359402B/es active IP Right Grant
- 2012-10-29 JP JP2014539116A patent/JP6095675B2/ja active Active
- 2012-10-29 EP EP12844368.6A patent/EP2771040B1/en active Active
- 2012-10-29 ES ES21171752T patent/ES2961982T3/es active Active
- 2012-10-29 KR KR1020147013908A patent/KR102068118B1/ko not_active Expired - Fee Related
- 2012-10-29 ES ES12844368T patent/ES2877715T3/es active Active
- 2012-10-29 AU AU2012328415A patent/AU2012328415B2/en not_active Ceased
- 2012-10-29 CA CA2853732A patent/CA2853732C/en active Active
- 2012-10-29 KR KR1020207000973A patent/KR102184970B1/ko not_active Expired - Fee Related
- 2012-10-29 CA CA3107935A patent/CA3107935A1/en not_active Abandoned
- 2012-10-29 EP EP21171752.5A patent/EP3878483B1/en active Active
- 2012-10-29 US US13/663,050 patent/US20130287818A1/en not_active Abandoned
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