JP2010537989A5 - - Google Patents
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- Publication number
- JP2010537989A5 JP2010537989A5 JP2010522977A JP2010522977A JP2010537989A5 JP 2010537989 A5 JP2010537989 A5 JP 2010537989A5 JP 2010522977 A JP2010522977 A JP 2010522977A JP 2010522977 A JP2010522977 A JP 2010522977A JP 2010537989 A5 JP2010537989 A5 JP 2010537989A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- buprenorphine
- daltons
- polyethylene glycol
- peg
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 5
- RMRJXGBAOAMLHD-IHFGGWKQSA-N buprenorphine Chemical compound C([C@]12[C@H]3OC=4C(O)=CC=C(C2=4)C[C@@H]2[C@]11CC[C@]3([C@H](C1)[C@](C)(O)C(C)(C)C)OC)CN2CC1CC1 RMRJXGBAOAMLHD-IHFGGWKQSA-N 0.000 claims 4
- 229920001223 polyethylene glycol Polymers 0.000 claims 4
- 229960001736 buprenorphine Drugs 0.000 claims 3
- 239000002245 particle Substances 0.000 claims 3
- 239000002202 Polyethylene glycol Substances 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 229920002562 Polyethylene Glycol 3350 Polymers 0.000 claims 1
- 229960001889 buprenorphine hydrochloride Drugs 0.000 claims 1
- UAIXRPCCYXNJMQ-RZIPZOSSSA-N buprenorphine hydrochlorie Chemical group [Cl-].C([C@]12[C@H]3OC=4C(O)=CC=C(C2=4)C[C@@H]2[C@]11CC[C@]3([C@H](C1)[C@](C)(O)C(C)(C)C)OC)C[NH+]2CC1CC1 UAIXRPCCYXNJMQ-RZIPZOSSSA-N 0.000 claims 1
- UZHSEJADLWPNLE-GRGSLBFTSA-N naloxone Chemical compound O=C([C@@H]1O2)CC[C@@]3(O)[C@H]4CC5=CC=C(O)C2=C5[C@@]13CCN4CC=C UZHSEJADLWPNLE-GRGSLBFTSA-N 0.000 claims 1
- 229960004127 naloxone Drugs 0.000 claims 1
- 239000004094 surface-active agent Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US96967207P | 2007-09-03 | 2007-09-03 | |
| PCT/US2008/010318 WO2009032246A2 (en) | 2007-09-03 | 2008-09-02 | Particulate compositions for delivery of poorly soluble drugs |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010537989A JP2010537989A (ja) | 2010-12-09 |
| JP2010537989A5 true JP2010537989A5 (https=) | 2011-10-20 |
Family
ID=40377549
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010522977A Pending JP2010537989A (ja) | 2007-09-03 | 2008-09-02 | 難溶性薬物の組成物及び送達方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US8377479B2 (https=) |
| EP (2) | EP2197429B9 (https=) |
| JP (1) | JP2010537989A (https=) |
| KR (1) | KR101545874B1 (https=) |
| AU (1) | AU2008296971B2 (https=) |
| CA (1) | CA2699172C (https=) |
| DK (1) | DK2197429T3 (https=) |
| ES (1) | ES2572157T3 (https=) |
| HK (1) | HK1226306A1 (https=) |
| HU (1) | HUE027537T2 (https=) |
| MX (1) | MX2010002409A (https=) |
| PL (1) | PL2197429T3 (https=) |
| SI (1) | SI2197429T1 (https=) |
| WO (1) | WO2009032246A2 (https=) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2654819T3 (es) * | 2001-10-18 | 2018-02-15 | Nektar Therapeutics | Conjugados poliméricos de antagonistas de opioides |
| US8852638B2 (en) | 2005-09-30 | 2014-10-07 | Durect Corporation | Sustained release small molecule drug formulation |
| EP2152315B1 (en) | 2007-05-25 | 2016-01-06 | Indivior UK Limited | Sustained delivery formulations of risperidone compounds |
| AU2008296971B2 (en) * | 2007-09-03 | 2014-10-02 | Nanoshift, Llc | Particulate compositions for delivery of poorly soluble drugs |
| AU2010206724A1 (en) * | 2009-01-22 | 2011-07-28 | Nanotherapeutics, Inc. | Process for preparing particles of opioids and compositions produced thereby |
| US20100273730A1 (en) * | 2009-04-27 | 2010-10-28 | Innopharmax, Inc. | Self-emulsifying pharmaceutical compositions of hydrophilic drugs and preparation thereof |
| US9125867B2 (en) * | 2010-02-24 | 2015-09-08 | Invincible Biotechnology | Diversion- and/or abuse-resistant compositions and methods for making the same |
| US9272044B2 (en) | 2010-06-08 | 2016-03-01 | Indivior Uk Limited | Injectable flowable composition buprenorphine |
| GB2481017B (en) * | 2010-06-08 | 2015-01-07 | Rb Pharmaceuticals Ltd | Microparticle buprenorphine suspension |
| HUE045889T2 (hu) | 2010-10-21 | 2020-01-28 | Rtu Pharmaceuticals Llc | Használatkész ketorolak készítmények |
| CA3042642A1 (en) | 2013-08-12 | 2015-02-19 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded immediate release abuse deterrent pill |
| US10172797B2 (en) | 2013-12-17 | 2019-01-08 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| US9492444B2 (en) | 2013-12-17 | 2016-11-15 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| GB201404139D0 (en) | 2014-03-10 | 2014-04-23 | Rb Pharmaceuticals Ltd | Sustained release buprenorphine solution formulations |
| CA2955229C (en) | 2014-07-17 | 2020-03-10 | Pharmaceutical Manufacturing Research Services, Inc. | Immediate release abuse deterrent liquid fill dosage form |
| WO2016064873A1 (en) | 2014-10-20 | 2016-04-28 | Pharmaceutical Manufacturing Research Services, Inc. | Extended release abuse deterrent liquid fill dosage form |
| US11331376B2 (en) | 2014-11-04 | 2022-05-17 | Innopharmax, Inc. | Oral administration of unstable or poorly-absorbed drugs |
| NZ731309A (en) | 2014-11-07 | 2022-02-25 | Indivior Uk Ltd | Buprenorphine dosing regimens |
| US10646484B2 (en) | 2017-06-16 | 2020-05-12 | Indivior Uk Limited | Methods to treat opioid use disorder |
| WO2019064026A1 (en) | 2017-09-29 | 2019-04-04 | Orexo Ab | NEW PHARMACEUTICAL COMPOSITIONS |
| AU2018390826B2 (en) | 2017-12-20 | 2024-09-12 | Purdue Pharma L.P. | Abuse deterrent morphine sulfate dosage forms |
| GB201904767D0 (en) | 2019-04-04 | 2019-05-22 | Orexo Ab | New pharmaceutical compositions |
| US12364692B2 (en) | 2020-02-14 | 2025-07-22 | Teikoku Pharma Usa, Inc. | Topical naloxone compositions and methods for using the same |
| GB202019335D0 (en) * | 2020-12-08 | 2021-01-20 | Artelo Biosciences Ltd | Pharmaceutical compositions |
| EP4719356A1 (en) | 2023-06-05 | 2026-04-08 | Nanopharmaceutics, Inc. | Compositions and methods for oral delivery of sustained release crystalline prx-3140 |
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| US4722941A (en) * | 1978-06-07 | 1988-02-02 | Kali-Chemie Pharma Gmbh | Readily absorbable pharmaceutical compositions of per se poorly absorbable pharmacologically active agents and preparation thereof |
| EP0012523B2 (en) * | 1978-11-20 | 1988-02-03 | American Home Products Corporation | Therapeutic compositions with enhanced bioavailability and process for their preparation |
| US4525339A (en) * | 1982-10-15 | 1985-06-25 | Hoffmann-La Roche Inc. | Enteric coated oral dosage form |
| JPS6163614A (ja) * | 1984-09-04 | 1986-04-01 | Yamanouchi Pharmaceut Co Ltd | 難溶性薬物の溶解速度向上方法 |
| GB8514665D0 (en) * | 1985-06-11 | 1985-07-10 | Eroceltique Sa | Oral pharmaceutical composition |
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| WO1991014423A1 (fr) * | 1990-03-20 | 1991-10-03 | Otsuka Pharmaceutical Co., Ltd. | Preparation a base de liposomes |
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| GB9606188D0 (en) * | 1996-03-23 | 1996-05-29 | Danbiosyst Uk | Pollysaccharide microspheres for the pulmonary delivery of drugs |
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| US20070020339A1 (en) * | 2005-07-20 | 2007-01-25 | Pharmorx Inc. | Compositions and methods for controlling abuse of medications |
| AU2008296971B2 (en) * | 2007-09-03 | 2014-10-02 | Nanoshift, Llc | Particulate compositions for delivery of poorly soluble drugs |
-
2008
- 2008-09-02 AU AU2008296971A patent/AU2008296971B2/en not_active Ceased
- 2008-09-02 EP EP08829074.7A patent/EP2197429B9/en not_active Not-in-force
- 2008-09-02 WO PCT/US2008/010318 patent/WO2009032246A2/en not_active Ceased
- 2008-09-02 DK DK08829074.7T patent/DK2197429T3/en active
- 2008-09-02 US US12/202,881 patent/US8377479B2/en active Active - Reinstated
- 2008-09-02 JP JP2010522977A patent/JP2010537989A/ja active Pending
- 2008-09-02 EP EP16163685.7A patent/EP3064198A1/en not_active Withdrawn
- 2008-09-02 CA CA2699172A patent/CA2699172C/en active Active
- 2008-09-02 SI SI200831607A patent/SI2197429T1/sl unknown
- 2008-09-02 ES ES08829074T patent/ES2572157T3/es active Active
- 2008-09-02 PL PL08829074.7T patent/PL2197429T3/pl unknown
- 2008-09-02 HU HUE08829074A patent/HUE027537T2/en unknown
- 2008-09-02 MX MX2010002409A patent/MX2010002409A/es active IP Right Grant
- 2008-09-02 KR KR1020107007177A patent/KR101545874B1/ko not_active Expired - Fee Related
-
2013
- 2013-01-15 US US13/741,915 patent/US9554996B2/en active Active
-
2016
- 2016-12-23 HK HK16114657.7A patent/HK1226306A1/en unknown
-
2017
- 2017-01-26 US US15/416,672 patent/US20170143698A1/en not_active Abandoned
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