JP2014530821A - ラキニモドおよびフィンゴリモドを組み合わせた多発性硬化症の治療 - Google Patents

ラキニモドおよびフィンゴリモドを組み合わせた多発性硬化症の治療 Download PDF

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JP2014530821A
JP2014530821A JP2014535874A JP2014535874A JP2014530821A JP 2014530821 A JP2014530821 A JP 2014530821A JP 2014535874 A JP2014535874 A JP 2014535874A JP 2014535874 A JP2014535874 A JP 2014535874A JP 2014530821 A JP2014530821 A JP 2014530821A
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laquinimod
fingolimod
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pharmaceutical composition
package
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JP2014530821A5 (OSRAM
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ハラック、フセイン
タルシク、ノラ
フラクスマン・ケイ、ジョエル
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テバ ファーマシューティカル インダストリーズ リミティド
テバ ファーマシューティカル インダストリーズ リミティド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4704—2-Quinolinones, e.g. carbostyril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
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    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
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    • A61K9/0012—Galenical forms characterised by the site of application
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    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
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    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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  • Rheumatology (AREA)
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  • Biochemistry (AREA)
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2014535874A 2011-10-12 2012-10-11 ラキニモドおよびフィンゴリモドを組み合わせた多発性硬化症の治療 Withdrawn JP2014530821A (ja)

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US201161546102P 2011-10-12 2011-10-12
US61/546,102 2011-10-12

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JP2014530821A5 JP2014530821A5 (OSRAM) 2015-12-03

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JP2017006394A Pending JP2017137298A (ja) 2011-10-12 2017-01-18 ラキニモドおよびフィンゴリモドを組み合わせた多発性硬化症の治療

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US (4) US8889627B2 (OSRAM)
EP (1) EP2766020A4 (OSRAM)
JP (2) JP2014530821A (OSRAM)
KR (1) KR20140101333A (OSRAM)
CN (2) CN106344576A (OSRAM)
AR (1) AR088458A1 (OSRAM)
AU (2) AU2012322706A1 (OSRAM)
BR (1) BR112014008731A2 (OSRAM)
CA (1) CA2851525A1 (OSRAM)
EA (1) EA201490748A1 (OSRAM)
HK (1) HK1199820A1 (OSRAM)
IL (1) IL231724A0 (OSRAM)
MX (1) MX2014004420A (OSRAM)
SG (1) SG11201401330YA (OSRAM)
TW (1) TW201321001A (OSRAM)
UY (1) UY34395A (OSRAM)
WO (1) WO2013055907A1 (OSRAM)
ZA (1) ZA201403378B (OSRAM)

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JP2015503658A (ja) * 2011-12-28 2015-02-02 ガレクティン・セラピューティクス・インコーポレイテッドＧａｌｅｃｔｉｎ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｉｎｃ． ヒト疾患処置用の新規糖薬剤の組成物

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US20170165236A1 (en) * 2013-11-01 2017-06-15 Celgene International Ii Sàrl Selective sphingosine 1 phosphate receptor modulators and combination therapy therewith
AU2014364447A1 (en) * 2013-12-20 2016-08-04 Teva Pharmaceutical Industries Ltd. Use of laquinimod to delay Huntington's disease progression
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JP2017514824A (ja) 2014-04-29 2017-06-08 テバ ファーマシューティカル インダストリーズ リミティド 能力障害度が高い再発寛解型多発性硬化症（ｒｒｍｓ）患者の処置のためのラキニモド
EP3193870A4 (en) * 2014-09-16 2018-04-25 Teva Pharmaceutical Industries Ltd. Treatment of neurodegenerative diseases with combination of laquinimod and fingolimod
CN107072988A (zh) * 2014-10-16 2017-08-18 诺华股份有限公司 包含辛波莫德和拉喹莫德的用于治疗多发性硬化症的组合
WO2016075543A1 (en) * 2014-11-13 2016-05-19 Teva Pharmaceutical Industries Ltd. Treatment of multiple sclerosis with combination of laquinimod and a phosphodiesterase-4 (pde4) inhibitor
EP3229786A4 (en) * 2014-12-10 2018-07-04 Teva Pharmaceutical Industries Ltd. Treatment of multiple sclerosis with combination of laquinimod and a statin
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