JP2014524241A - コラーゲン７及び関連する方法 - Google Patents

コラーゲン７及び関連する方法 Download PDF

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Publication number
JP2014524241A
JP2014524241A JP2014524112A JP2014524112A JP2014524241A JP 2014524241 A JP2014524241 A JP 2014524241A JP 2014524112 A JP2014524112 A JP 2014524112A JP 2014524112 A JP2014524112 A JP 2014524112A JP 2014524241 A JP2014524241 A JP 2014524241A
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JP
Japan
Prior art keywords
collagen
cell
functional fragment
recombinant
express
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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JP2014524112A
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English (en)
Japanese (ja)
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JP2014524241A5 (enExample
Inventor
ソウザ，マーク デ
ヴィスワナータン，マリニ
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Lotus Tissue Repair Inc
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Lotus Tissue Repair Inc
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Application filed by Lotus Tissue Repair Inc filed Critical Lotus Tissue Repair Inc
Publication of JP2014524241A publication Critical patent/JP2014524241A/ja
Publication of JP2014524241A5 publication Critical patent/JP2014524241A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/13—Dipeptidases (3.4.13)
    • C12Y304/13009—Xaa-Pro dipeptidase (3.4.13.9) i.e. prolidase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/22—Vectors comprising a coding region that has been codon optimised for expression in a respective host
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1081—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/485—Exopeptidases (3.4.11-3.4.19)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/11—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors (1.14.11)
    • C12Y114/11002—Procollagen-proline dioxygenase (1.14.11.2), i.e. proline-hydroxylase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
JP2014524112A 2011-08-03 2012-08-03 コラーゲン７及び関連する方法 Pending JP2014524241A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161514796P 2011-08-03 2011-08-03
US61/514,796 2011-08-03
PCT/US2012/049553 WO2013020064A1 (en) 2011-08-03 2012-08-03 Collagen 7 and related methods

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2017171852A Division JP2017209117A (ja) 2011-08-03 2017-09-07 コラーゲン７及び関連する方法

Publications (2)

Publication Number Publication Date
JP2014524241A true JP2014524241A (ja) 2014-09-22
JP2014524241A5 JP2014524241A5 (enExample) 2015-07-23

Family

ID=47629706

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2014524112A Pending JP2014524241A (ja) 2011-08-03 2012-08-03 コラーゲン７及び関連する方法
JP2017171852A Abandoned JP2017209117A (ja) 2011-08-03 2017-09-07 コラーゲン７及び関連する方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2017171852A Abandoned JP2017209117A (ja) 2011-08-03 2017-09-07 コラーゲン７及び関連する方法

Country Status (10)

Country Link
US (1) US9676837B2 (enExample)
EP (1) EP2753704A4 (enExample)
JP (2) JP2014524241A (enExample)
KR (1) KR20140054160A (enExample)
CN (2) CN108165593A (enExample)
AU (2) AU2012289916B2 (enExample)
BR (1) BR112014002546A2 (enExample)
CA (1) CA2843896A1 (enExample)
MX (1) MX351565B (enExample)
WO (1) WO2013020064A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019058165A (ja) * 2017-09-22 2019-04-18 モダン メドウ，インコーポレイテッド 組換え酵母株
JP2019511498A (ja) * 2016-03-16 2019-04-25 フェニックス ティシュー リペア インコーポレイテッドＰｈｏｅｎｉｘ Ｔｉｓｓｕｅ Ｒｅｐａｉｒ，Ｉｎｃ． ７型コラーゲンの精製方法

Families Citing this family (23)

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ES2328446T5 (es) 2000-02-04 2014-02-27 Children's Hospital Research Foundation Uso de lipasa ácida lisosomal para tratar la aterosclerosis y enfermedades asociadas
MX338426B (es) 2010-04-23 2016-04-15 Synageva Biopharma Corp Enzima de enfermedad del almacenamiento lisosomico.
DK2613798T4 (en) 2010-09-09 2018-04-16 Synageva Biopharma Corp USING LYSOSOMAL SUR LIPASE TO TREAT PATIENTS WITHOUT LYSOSOMAL SUR LIPASE
EP2675472A4 (en) 2011-02-15 2014-09-17 Synageva Biopharma Corp METHOD FOR THE TREATMENT OF LACK OF LYSOSOMAL SAURER LIPASE
US9040484B2 (en) * 2011-04-26 2015-05-26 The Board Of Trustees Of The Leland Stanford Junior University Production and delivery of a stable collagen
CN105940110A (zh) 2014-01-31 2016-09-14 菲克特生物科学股份有限公司 用于核酸产生和递送的方法和产品
US10227394B2 (en) 2014-04-08 2019-03-12 University Of Southern California Polypeptide compositions with type VII collagen fibronectin type III-like repeats and treatment methods for wound closure and healing
KR102204367B1 (ko) * 2014-07-16 2021-01-19 주식회사 엘지생활건강 피부 주름 개선용 화장료 조성물
WO2016131052A1 (en) 2015-02-13 2016-08-18 Factor Bioscience Inc. Nucleic acid products and methods of administration thereof
GB201601571D0 (en) * 2016-01-28 2016-03-16 Nordic Bioscience As Collagen type Vll alpha 1 assay
IL308824A (en) 2016-08-17 2024-01-01 Factor Bioscience Inc Nucleic acid products and methods of administration thereof
US11180541B2 (en) 2017-09-28 2021-11-23 Geltor, Inc. Recombinant collagen and elastin molecules and uses thereof
CN109022464A (zh) * 2018-07-02 2018-12-18 西安巨子生物基因技术股份有限公司 重组人源型胶原蛋白的羟基化方法
TWI818166B (zh) * 2019-03-27 2023-10-11 美商菲尼克斯組織修復公司 用於生產膠原蛋白7組合物之系統及方法
TW202104254A (zh) 2019-04-12 2021-02-01 美商格爾托公司 重組彈性蛋白及其生產
JP7699552B2 (ja) 2019-07-03 2025-06-27 ファクター バイオサイエンス インコーポレイテッド カチオン性脂質及びその使用
US10501404B1 (en) 2019-07-30 2019-12-10 Factor Bioscience Inc. Cationic lipids and transfection methods
AU2021211721A1 (en) 2020-01-24 2022-08-18 Geltor, Inc. Animal-free dietary collagen
KR20240004264A (ko) * 2021-03-04 2024-01-11 젤라텍, 인크. 배양된 동물 세포로부터의 콜라겐을 사용한 재료의 제조 방법
US20240424065A1 (en) 2021-10-12 2024-12-26 Phoenix Tissue Repair, Inc. Collagen 7 protein replacement therapy
CN117143223B (zh) * 2022-08-23 2024-03-08 山西锦波生物医药股份有限公司 一种生物合成人体结构性材料的制备方法
CN116854807A (zh) * 2023-07-26 2023-10-10 浙江大学 一种重组人源ⅶ型胶原蛋白及其制备方法与应用
CN120137008B (zh) * 2025-03-18 2025-09-26 广东普言生物科技有限公司 一种重组Ⅶ型胶原蛋白Pro.C7及其制备方法和应用

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US9040484B2 (en) 2011-04-26 2015-05-26 The Board Of Trustees Of The Leland Stanford Junior University Production and delivery of a stable collagen

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019511498A (ja) * 2016-03-16 2019-04-25 フェニックス ティシュー リペア インコーポレイテッドＰｈｏｅｎｉｘ Ｔｉｓｓｕｅ Ｒｅｐａｉｒ，Ｉｎｃ． ７型コラーゲンの精製方法
JP2022016605A (ja) * 2016-03-16 2022-01-21 フェニックス ティシュー リペア インコーポレイテッド ７型コラーゲンの精製方法
JP7340583B2 (ja) 2016-03-16 2023-09-07 フェニックス ティシュー リペア インコーポレイテッド ７型コラーゲンの精製方法
JP2019058165A (ja) * 2017-09-22 2019-04-18 モダン メドウ，インコーポレイテッド 組換え酵母株
JP2021036889A (ja) * 2017-09-22 2021-03-11 モダン メドウ，インコーポレイテッド 組換え酵母株

Also Published As

Publication number Publication date
JP2017209117A (ja) 2017-11-30
EP2753704A4 (en) 2015-07-08
CN103842517A (zh) 2014-06-04
WO2013020064A1 (en) 2013-02-07
KR20140054160A (ko) 2014-05-08
AU2012289916B2 (en) 2017-08-03
CA2843896A1 (en) 2013-02-07
EP2753704A1 (en) 2014-07-16
US9676837B2 (en) 2017-06-13
MX2014001383A (es) 2014-08-26
BR112014002546A2 (pt) 2017-03-14
AU2017254910A1 (en) 2017-11-23
US20150011733A1 (en) 2015-01-08
CN108165593A (zh) 2018-06-15
MX351565B (es) 2017-10-19
AU2012289916A1 (en) 2014-02-20

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