JP2014521958A5 - - Google Patents
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- JP2014521958A5 JP2014521958A5 JP2014523039A JP2014523039A JP2014521958A5 JP 2014521958 A5 JP2014521958 A5 JP 2014521958A5 JP 2014523039 A JP2014523039 A JP 2014523039A JP 2014523039 A JP2014523039 A JP 2014523039A JP 2014521958 A5 JP2014521958 A5 JP 2014521958A5
- Authority
- JP
- Japan
- Prior art keywords
- fluid
- cancer
- serous
- cells
- ligand
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161512576P | 2011-07-28 | 2011-07-28 | |
| US61/512,576 | 2011-07-28 | ||
| PCT/US2012/048452 WO2013016600A2 (en) | 2011-07-28 | 2012-07-27 | Methods and reagents for diagnosing conditions and characterization of tumor cells associated with serous fluids |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014521958A JP2014521958A (ja) | 2014-08-28 |
| JP2014521958A5 true JP2014521958A5 (https=) | 2015-09-03 |
Family
ID=46650901
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014523039A Pending JP2014521958A (ja) | 2011-07-28 | 2012-07-27 | 胸腔内液若しくは漿液と関連する腫瘍細胞の特徴づけによる癌の診断方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20140295426A1 (https=) |
| EP (1) | EP2737317A2 (https=) |
| JP (1) | JP2014521958A (https=) |
| IL (1) | IL230687A0 (https=) |
| TW (1) | TW201312117A (https=) |
| WO (1) | WO2013016600A2 (https=) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6238856B2 (ja) * | 2014-08-25 | 2017-11-29 | シスメックス株式会社 | 尿中異型細胞の分析方法、尿分析装置および体液中異型細胞の分析方法 |
| CA3000438C (en) * | 2015-09-28 | 2024-05-14 | The Governing Council Of The University Of Toronto | Device for magnetic profiling of particles in a flow |
| US10696961B2 (en) | 2017-12-01 | 2020-06-30 | Global Life Sciences Solutions Usa Llc | Magnetic cell isolation techniques |
| CA3082861A1 (en) * | 2017-12-01 | 2019-06-06 | General Electric Company | Methods for cell enrichment and isolation |
| EP4073511A4 (en) | 2019-12-12 | 2024-01-17 | University of Miami | MATERIALS AND METHODS FOR DETECTING EXTRACELLULAR VESICLES |
| CN115997008A (zh) | 2020-04-22 | 2023-04-21 | 艾欧凡斯生物治疗公司 | 协调用于患者特异性免疫疗法的细胞的制造的系统和方法 |
| CA3177413A1 (en) | 2020-05-04 | 2021-11-11 | Michelle SIMPSON-ABELSON | Selection of improved tumor reactive t-cells |
| CA3176826A1 (en) | 2020-05-04 | 2021-11-11 | Iovance Biotherapeutics, Inc. | Processes for production of tumor infiltrating lymphocytes and uses of the same in immunotherapy |
| JP2023546359A (ja) | 2020-10-06 | 2023-11-02 | アイオバンス バイオセラピューティクス,インコーポレイテッド | 腫瘍浸潤リンパ球療法によるnsclc患者の治療 |
| WO2022076606A1 (en) | 2020-10-06 | 2022-04-14 | Iovance Biotherapeutics, Inc. | Treatment of nsclc patients with tumor infiltrating lymphocyte therapies |
| EP4259164A1 (en) | 2020-12-11 | 2023-10-18 | Iovance Biotherapeutics, Inc. | Treatment of cancer patients with tumor infiltrating lymphocyte therapies in combination with braf inhibitors and/or mek inhibitors |
| EP4262827A1 (en) | 2020-12-17 | 2023-10-25 | Iovance Biotherapeutics, Inc. | Treatment of cancers with tumor infiltrating lymphocytes |
| AU2021401302A1 (en) | 2020-12-17 | 2023-07-06 | Iovance Biotherapeutics, Inc. | Treatment with tumor infiltrating lymphocyte therapies in combination with ctla-4 and pd-1 inhibitors |
| JP2024501845A (ja) | 2020-12-31 | 2024-01-16 | アイオバンス バイオセラピューティクス,インコーポレイテッド | 腫瘍浸潤リンパ球の自動化された産生のためのデバイス及びプロセス |
| EP4301138A2 (en) | 2021-03-05 | 2024-01-10 | Iovance Biotherapeutics, Inc. | Tumor storage and cell culture compositions |
| US20240191191A1 (en) | 2021-03-19 | 2024-06-13 | Iovance Biotherapeutics, Inc. | Methods for infiltrating lymphocyte (til) expansion related to cd39/cd69 selection and gene knockout in tils |
| JP2024512029A (ja) | 2021-03-25 | 2024-03-18 | アイオバンス バイオセラピューティクス,インコーポレイテッド | T細胞共培養効力アッセイのための方法及び組成物、ならびに細胞療法製品との使用 |
| CA3215830A1 (en) | 2021-04-19 | 2022-10-27 | Rafael CUBAS | Chimeric costimulatory receptors, chemokine receptors, and the use of same in cellular immunotherapies |
| JP2024519029A (ja) | 2021-05-17 | 2024-05-08 | アイオバンス バイオセラピューティクス,インコーポレイテッド | Pd-1遺伝子編集された腫瘍浸潤リンパ球及び免疫療法におけるその使用 |
| JP2024527961A (ja) | 2021-07-28 | 2024-07-26 | アイオバンス バイオセラピューティクス,インコーポレイテッド | Kras阻害剤と併用した腫瘍浸潤リンパ球療法によるがん患者の治療 |
| WO2023039488A1 (en) | 2021-09-09 | 2023-03-16 | Iovance Biotherapeutics, Inc. | Processes for generating til products using pd-1 talen knockdown |
| US20250000903A1 (en) | 2021-09-24 | 2025-01-02 | Iovance Biotherapeutics, Inc. | Expansion processes and agents for tumor infiltrating lymphocytes |
| WO2023077015A2 (en) | 2021-10-27 | 2023-05-04 | Iovance Biotherapeutics, Inc. | Systems and methods for coordinating manufacturing of cells for patient-specific immunotherapy |
| CA3237410A1 (en) | 2021-11-10 | 2023-05-19 | Friedrich Graf Finck VON FINCKENSTEIN | Methods of expansion treatment utilizing cd8 tumor infiltrating lymphocytes |
| CA3243416A1 (en) | 2022-01-28 | 2023-08-03 | Iovance Biotherapeutics, Inc. | TUMOR INFILTRATION LYMPHOCYTES MODIFIED TO EXPRESS PAYLOADS |
| JP2025512401A (ja) | 2022-04-15 | 2025-04-17 | アイオバンス バイオセラピューティクス,インコーポレイテッド | 特定のサイトカインの組み合わせ及び/またはAKTi処理を使用したTIL拡張プロセス |
| WO2024011114A1 (en) | 2022-07-06 | 2024-01-11 | Iovance Biotherapeutics, Inc. | Devices and processes for automated production of tumor infiltrating lymphocytes |
| US20260021181A1 (en) | 2022-08-01 | 2026-01-22 | Iovance Biotherapeutics, Inc. | Chimeric costimulatory receptors, chemokine receptors, and the use of same in cellular immunotherapies |
| EP4612277A1 (en) | 2022-11-04 | 2025-09-10 | Iovance Biotherapeutics, Inc. | Methods for tumor infiltrating lymphocyte (til) expansion related to cd39/cd103 selection |
| JP2025539816A (ja) | 2022-11-21 | 2025-12-09 | アイオバンス バイオセラピューティクス,インコーポレイテッド | 腫瘍浸潤リンパ球の増幅のための2次元プロセス及びそれからの治療法 |
| WO2025015318A2 (en) | 2023-07-13 | 2025-01-16 | Iovance Biotherapeutics, Inc. | Cytokine encoding lentiviral vectors and uses thereof for making tumor infiltrating lymphocytes |
| WO2025019790A1 (en) | 2023-07-19 | 2025-01-23 | Iovance Biotherapeutics, Inc. | Treatment of cancer patients with tumor infiltrating lymphocyte therapies in combination with trop-2 targeting adc |
| WO2025101484A1 (en) | 2023-11-06 | 2025-05-15 | Iovance Biotherapeutics, Inc. | Treatment of endometrial cancers with tumor infiltrating lymphocyte therapies |
| WO2026035866A1 (en) | 2024-08-07 | 2026-02-12 | Iovance Biotherapeutics, Inc. | Treatment of cancer patients with tumor infiltrating lymphocyte therapies in combination with a lag-3 inhibitor and a pd-1 inhibitor |
| WO2026050217A2 (en) | 2024-08-27 | 2026-03-05 | Iovance Biotherapeutics, Inc. | Engineered artificial antigen presenting cells and lipid nanoparticles for tumor infiltrating lymphocyte expansion |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4939240A (en) | 1983-03-04 | 1990-07-03 | Health Research, Inc. | Monoclonal antibodies to human breast carcinoma cells and their use in diagnosis and therapy |
| JPH0763389B2 (ja) * | 1986-10-28 | 1995-07-12 | 協和醗酵工業株式会社 | 抗ヒト中皮細胞単クローン性抗体 |
| AU656716B2 (en) | 1989-09-15 | 1995-02-16 | Genetic Systems Corporation | Hybridoma CT43 producing a monoclonal antibody to a mucin epitope of colorectal cancer |
| CA2144750A1 (en) | 1992-09-17 | 1994-03-31 | Rolf Stahel | Tumor-specific antibodies and antigen |
| NO180658C (no) * | 1994-03-10 | 1997-05-21 | Oeystein Fodstad | Fremgangsmåte og anordning for deteksjon av spesifikke målceller i spesialiserte eller blandede cellepopulasjoner og opplösninger som inneholder blandede cellepopulasjoner |
| US6660159B1 (en) | 1996-06-07 | 2003-12-09 | Immunivest Corporation | Magnetic separation apparatus and methods |
| US6890426B2 (en) | 1996-06-07 | 2005-05-10 | Immunivest Corporation | Magnetic separation apparatus and methods |
| US6790366B2 (en) | 1996-06-07 | 2004-09-14 | Immunivest Corporation | Magnetic separation apparatus and methods |
| JP3996644B2 (ja) | 1996-06-07 | 2007-10-24 | イムニベスト・コーポレイション | 外部及び内部勾配を有する磁気分離 |
| US6136182A (en) | 1996-06-07 | 2000-10-24 | Immunivest Corporation | Magnetic devices and sample chambers for examination and manipulation of cells |
| BR9907852A (pt) | 1998-02-12 | 2000-10-24 | Immunivest Corp | Processos para detectar e enumerar células raras e cancerosas em uma população celular mista, para diagnosticar câncer de estágio precoce em um paciente de teste, para determinar a probabilidade de recorrência de câncer em um paciente humano anteriormente tratado de câncer, para distinguir um carcinoma confinado ao órgão de um carcinoma com propriedades metastáticas, para acompanhar a situação de remissão em um paciente humano com câncer que passa pelo tratamento de terapia contra o câncer e para aumentar quantidades de células epiteliais circulantes em uma amostra de sangue, partìcula magnética revestida, composição, conjuntos de teste para avaliar uma amostra de paciente quanto a presença de células raras circulantes, quanto a presença de células de tumor circulantes, quanto a presença de células de câncer de mama circulantes, quanto a presença de células de câncer de próstata circulantes, quanto a presença de células de câncer de cólon circulantes, quanto a presença de células de câncer de bexiga circulantes e para monitorar um paciente quanto a recorrência de câncer, e, fração de sangue periférico enriquecido quanto a células neoplásticas circulantes |
| US7282350B2 (en) | 1998-02-12 | 2007-10-16 | Immunivest Corporation | Labeled cell sets for use as functional controls in rare cell detection assays |
| US6623982B1 (en) | 1999-07-12 | 2003-09-23 | Immunivest Corporation | Increased separation efficiency via controlled aggregation of magnetic nanoparticles |
| CA2434604C (en) | 2001-02-12 | 2010-09-28 | Immunivest Corporation | Cartridge for containing a specimen sample for optical analysis |
| WO2003019141A2 (en) * | 2001-08-23 | 2003-03-06 | Immunivest Corporation | Analysis of circulating tumor cells, fragments, and debris |
| GB2395270B (en) * | 2002-11-14 | 2006-08-16 | Univ Nottingham | Tumour marker proteins and uses thereof |
| JP4912894B2 (ja) * | 2004-02-19 | 2012-04-11 | イェール ユニバーシティー | プロテオーム技術を使用した癌タンパク質バイオマーカーの同定 |
| US20060024824A1 (en) * | 2004-07-16 | 2006-02-02 | Steven Woodside | Magnetic cell separation method |
| EP1888238B1 (en) * | 2005-04-21 | 2014-08-13 | California Institute of Technology | Parylene membrane filters |
| US7846743B2 (en) * | 2005-04-21 | 2010-12-07 | California Institute Of Technology | Uses of parylene membrane filters |
| FR2896881B1 (fr) * | 2006-01-31 | 2008-04-18 | Biomerieux Sa | Procede de dosage du prongf pour le diagnostic in vitro du cancer du sein et utilisation du prongf en therapie |
| CA2661669C (en) * | 2006-08-23 | 2017-02-14 | Korea Research Institute Of Bioscience And Biotechnology | A pharmaceutical composition for treating cholangiocarcinoma, a method for inhibiting growth or invasion of cholangiocarcinoma and a method for treating cholangniocarcinoma |
| EP2037265A1 (en) * | 2007-09-17 | 2009-03-18 | Adnagen AG | Solid phase cell isolation and/or enrichment method |
| US8252904B2 (en) * | 2009-03-06 | 2012-08-28 | Tripath Imaging, Inc. | Glycodelin monoclonal antibodies and methods for their use in the detection of ovarian cancer |
-
2012
- 2012-07-27 EP EP12746193.7A patent/EP2737317A2/en not_active Withdrawn
- 2012-07-27 US US14/235,185 patent/US20140295426A1/en not_active Abandoned
- 2012-07-27 TW TW101127107A patent/TW201312117A/zh unknown
- 2012-07-27 WO PCT/US2012/048452 patent/WO2013016600A2/en not_active Ceased
- 2012-07-27 JP JP2014523039A patent/JP2014521958A/ja active Pending
-
2014
- 2014-01-28 IL IL230687A patent/IL230687A0/en unknown
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