JP2014521958A - 胸腔内液若しくは漿液と関連する腫瘍細胞の特徴づけによる癌の診断方法 - Google Patents
胸腔内液若しくは漿液と関連する腫瘍細胞の特徴づけによる癌の診断方法 Download PDFInfo
- Publication number
- JP2014521958A JP2014521958A JP2014523039A JP2014523039A JP2014521958A JP 2014521958 A JP2014521958 A JP 2014521958A JP 2014523039 A JP2014523039 A JP 2014523039A JP 2014523039 A JP2014523039 A JP 2014523039A JP 2014521958 A JP2014521958 A JP 2014521958A
- Authority
- JP
- Japan
- Prior art keywords
- fluid
- cells
- cancer
- ligand
- intrathoracic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6841—In situ hybridisation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
- G01N1/4077—Concentrating samples by other techniques involving separation of suspended solids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
- G01N33/57585—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds identifiable in body fluids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161512576P | 2011-07-28 | 2011-07-28 | |
| US61/512,576 | 2011-07-28 | ||
| PCT/US2012/048452 WO2013016600A2 (en) | 2011-07-28 | 2012-07-27 | Methods and reagents for diagnosing conditions and characterization of tumor cells associated with serous fluids |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014521958A true JP2014521958A (ja) | 2014-08-28 |
| JP2014521958A5 JP2014521958A5 (https=) | 2015-09-03 |
Family
ID=46650901
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014523039A Pending JP2014521958A (ja) | 2011-07-28 | 2012-07-27 | 胸腔内液若しくは漿液と関連する腫瘍細胞の特徴づけによる癌の診断方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20140295426A1 (https=) |
| EP (1) | EP2737317A2 (https=) |
| JP (1) | JP2014521958A (https=) |
| IL (1) | IL230687A0 (https=) |
| TW (1) | TW201312117A (https=) |
| WO (1) | WO2013016600A2 (https=) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6238856B2 (ja) * | 2014-08-25 | 2017-11-29 | シスメックス株式会社 | 尿中異型細胞の分析方法、尿分析装置および体液中異型細胞の分析方法 |
| CA3000438C (en) * | 2015-09-28 | 2024-05-14 | The Governing Council Of The University Of Toronto | Device for magnetic profiling of particles in a flow |
| US10696961B2 (en) | 2017-12-01 | 2020-06-30 | Global Life Sciences Solutions Usa Llc | Magnetic cell isolation techniques |
| CA3082861A1 (en) * | 2017-12-01 | 2019-06-06 | General Electric Company | Methods for cell enrichment and isolation |
| EP4073511A4 (en) | 2019-12-12 | 2024-01-17 | University of Miami | MATERIALS AND METHODS FOR DETECTING EXTRACELLULAR VESICLES |
| CN115997008A (zh) | 2020-04-22 | 2023-04-21 | 艾欧凡斯生物治疗公司 | 协调用于患者特异性免疫疗法的细胞的制造的系统和方法 |
| CA3177413A1 (en) | 2020-05-04 | 2021-11-11 | Michelle SIMPSON-ABELSON | Selection of improved tumor reactive t-cells |
| CA3176826A1 (en) | 2020-05-04 | 2021-11-11 | Iovance Biotherapeutics, Inc. | Processes for production of tumor infiltrating lymphocytes and uses of the same in immunotherapy |
| JP2023546359A (ja) | 2020-10-06 | 2023-11-02 | アイオバンス バイオセラピューティクス,インコーポレイテッド | 腫瘍浸潤リンパ球療法によるnsclc患者の治療 |
| WO2022076606A1 (en) | 2020-10-06 | 2022-04-14 | Iovance Biotherapeutics, Inc. | Treatment of nsclc patients with tumor infiltrating lymphocyte therapies |
| EP4259164A1 (en) | 2020-12-11 | 2023-10-18 | Iovance Biotherapeutics, Inc. | Treatment of cancer patients with tumor infiltrating lymphocyte therapies in combination with braf inhibitors and/or mek inhibitors |
| EP4262827A1 (en) | 2020-12-17 | 2023-10-25 | Iovance Biotherapeutics, Inc. | Treatment of cancers with tumor infiltrating lymphocytes |
| AU2021401302A1 (en) | 2020-12-17 | 2023-07-06 | Iovance Biotherapeutics, Inc. | Treatment with tumor infiltrating lymphocyte therapies in combination with ctla-4 and pd-1 inhibitors |
| JP2024501845A (ja) | 2020-12-31 | 2024-01-16 | アイオバンス バイオセラピューティクス,インコーポレイテッド | 腫瘍浸潤リンパ球の自動化された産生のためのデバイス及びプロセス |
| EP4301138A2 (en) | 2021-03-05 | 2024-01-10 | Iovance Biotherapeutics, Inc. | Tumor storage and cell culture compositions |
| US20240191191A1 (en) | 2021-03-19 | 2024-06-13 | Iovance Biotherapeutics, Inc. | Methods for infiltrating lymphocyte (til) expansion related to cd39/cd69 selection and gene knockout in tils |
| JP2024512029A (ja) | 2021-03-25 | 2024-03-18 | アイオバンス バイオセラピューティクス,インコーポレイテッド | T細胞共培養効力アッセイのための方法及び組成物、ならびに細胞療法製品との使用 |
| CA3215830A1 (en) | 2021-04-19 | 2022-10-27 | Rafael CUBAS | Chimeric costimulatory receptors, chemokine receptors, and the use of same in cellular immunotherapies |
| JP2024519029A (ja) | 2021-05-17 | 2024-05-08 | アイオバンス バイオセラピューティクス,インコーポレイテッド | Pd-1遺伝子編集された腫瘍浸潤リンパ球及び免疫療法におけるその使用 |
| JP2024527961A (ja) | 2021-07-28 | 2024-07-26 | アイオバンス バイオセラピューティクス,インコーポレイテッド | Kras阻害剤と併用した腫瘍浸潤リンパ球療法によるがん患者の治療 |
| WO2023039488A1 (en) | 2021-09-09 | 2023-03-16 | Iovance Biotherapeutics, Inc. | Processes for generating til products using pd-1 talen knockdown |
| US20250000903A1 (en) | 2021-09-24 | 2025-01-02 | Iovance Biotherapeutics, Inc. | Expansion processes and agents for tumor infiltrating lymphocytes |
| WO2023077015A2 (en) | 2021-10-27 | 2023-05-04 | Iovance Biotherapeutics, Inc. | Systems and methods for coordinating manufacturing of cells for patient-specific immunotherapy |
| CA3237410A1 (en) | 2021-11-10 | 2023-05-19 | Friedrich Graf Finck VON FINCKENSTEIN | Methods of expansion treatment utilizing cd8 tumor infiltrating lymphocytes |
| CA3243416A1 (en) | 2022-01-28 | 2023-08-03 | Iovance Biotherapeutics, Inc. | TUMOR INFILTRATION LYMPHOCYTES MODIFIED TO EXPRESS PAYLOADS |
| JP2025512401A (ja) | 2022-04-15 | 2025-04-17 | アイオバンス バイオセラピューティクス,インコーポレイテッド | 特定のサイトカインの組み合わせ及び/またはAKTi処理を使用したTIL拡張プロセス |
| WO2024011114A1 (en) | 2022-07-06 | 2024-01-11 | Iovance Biotherapeutics, Inc. | Devices and processes for automated production of tumor infiltrating lymphocytes |
| US20260021181A1 (en) | 2022-08-01 | 2026-01-22 | Iovance Biotherapeutics, Inc. | Chimeric costimulatory receptors, chemokine receptors, and the use of same in cellular immunotherapies |
| EP4612277A1 (en) | 2022-11-04 | 2025-09-10 | Iovance Biotherapeutics, Inc. | Methods for tumor infiltrating lymphocyte (til) expansion related to cd39/cd103 selection |
| JP2025539816A (ja) | 2022-11-21 | 2025-12-09 | アイオバンス バイオセラピューティクス,インコーポレイテッド | 腫瘍浸潤リンパ球の増幅のための2次元プロセス及びそれからの治療法 |
| WO2025015318A2 (en) | 2023-07-13 | 2025-01-16 | Iovance Biotherapeutics, Inc. | Cytokine encoding lentiviral vectors and uses thereof for making tumor infiltrating lymphocytes |
| WO2025019790A1 (en) | 2023-07-19 | 2025-01-23 | Iovance Biotherapeutics, Inc. | Treatment of cancer patients with tumor infiltrating lymphocyte therapies in combination with trop-2 targeting adc |
| WO2025101484A1 (en) | 2023-11-06 | 2025-05-15 | Iovance Biotherapeutics, Inc. | Treatment of endometrial cancers with tumor infiltrating lymphocyte therapies |
| WO2026035866A1 (en) | 2024-08-07 | 2026-02-12 | Iovance Biotherapeutics, Inc. | Treatment of cancer patients with tumor infiltrating lymphocyte therapies in combination with a lag-3 inhibitor and a pd-1 inhibitor |
| WO2026050217A2 (en) | 2024-08-27 | 2026-03-05 | Iovance Biotherapeutics, Inc. | Engineered artificial antigen presenting cells and lipid nanoparticles for tumor infiltrating lymphocyte expansion |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63109793A (ja) * | 1986-10-28 | 1988-05-14 | Kyowa Hakko Kogyo Co Ltd | 抗ヒト中皮細胞単クロ−ン性抗体 |
| JPH09510779A (ja) * | 1994-03-10 | 1997-10-28 | フォドスタッド オイステイン | 特定化あるいは混合した細胞母集団または混合細胞母集団を含む溶液内の特定標的細胞を検出する方法および装置 |
| JP2008538509A (ja) * | 2005-04-21 | 2008-10-30 | カリフォルニア インスティチュート オブ テクノロジー | パリレンメンブレンフィルターの使用 |
| JP2009525478A (ja) * | 2006-01-31 | 2009-07-09 | ビオメリュー | 癌、特に乳癌、甲状腺癌及び肺癌のインビトロ診断のためのProNGFアッセイのための方法とProNGFの治療的使用 |
| JP2010501549A (ja) * | 2006-08-23 | 2010-01-21 | コリア リサーチ インスティテュート オブ バイオサイエンス アンド バイオテクノロジー | 胆管癌治療用薬学的組成物、胆管癌の成長または浸潤抑制方法、および胆管癌の治療方法 |
| WO2010102177A1 (en) * | 2009-03-06 | 2010-09-10 | Becton, Dickinson And Company | Glycodelin monoclonal antibodies and methods for their use in the detection of ovarian cancer |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4939240A (en) | 1983-03-04 | 1990-07-03 | Health Research, Inc. | Monoclonal antibodies to human breast carcinoma cells and their use in diagnosis and therapy |
| AU656716B2 (en) | 1989-09-15 | 1995-02-16 | Genetic Systems Corporation | Hybridoma CT43 producing a monoclonal antibody to a mucin epitope of colorectal cancer |
| CA2144750A1 (en) | 1992-09-17 | 1994-03-31 | Rolf Stahel | Tumor-specific antibodies and antigen |
| US6660159B1 (en) | 1996-06-07 | 2003-12-09 | Immunivest Corporation | Magnetic separation apparatus and methods |
| US6890426B2 (en) | 1996-06-07 | 2005-05-10 | Immunivest Corporation | Magnetic separation apparatus and methods |
| US6790366B2 (en) | 1996-06-07 | 2004-09-14 | Immunivest Corporation | Magnetic separation apparatus and methods |
| JP3996644B2 (ja) | 1996-06-07 | 2007-10-24 | イムニベスト・コーポレイション | 外部及び内部勾配を有する磁気分離 |
| US6136182A (en) | 1996-06-07 | 2000-10-24 | Immunivest Corporation | Magnetic devices and sample chambers for examination and manipulation of cells |
| BR9907852A (pt) | 1998-02-12 | 2000-10-24 | Immunivest Corp | Processos para detectar e enumerar células raras e cancerosas em uma população celular mista, para diagnosticar câncer de estágio precoce em um paciente de teste, para determinar a probabilidade de recorrência de câncer em um paciente humano anteriormente tratado de câncer, para distinguir um carcinoma confinado ao órgão de um carcinoma com propriedades metastáticas, para acompanhar a situação de remissão em um paciente humano com câncer que passa pelo tratamento de terapia contra o câncer e para aumentar quantidades de células epiteliais circulantes em uma amostra de sangue, partìcula magnética revestida, composição, conjuntos de teste para avaliar uma amostra de paciente quanto a presença de células raras circulantes, quanto a presença de células de tumor circulantes, quanto a presença de células de câncer de mama circulantes, quanto a presença de células de câncer de próstata circulantes, quanto a presença de células de câncer de cólon circulantes, quanto a presença de células de câncer de bexiga circulantes e para monitorar um paciente quanto a recorrência de câncer, e, fração de sangue periférico enriquecido quanto a células neoplásticas circulantes |
| US7282350B2 (en) | 1998-02-12 | 2007-10-16 | Immunivest Corporation | Labeled cell sets for use as functional controls in rare cell detection assays |
| US6623982B1 (en) | 1999-07-12 | 2003-09-23 | Immunivest Corporation | Increased separation efficiency via controlled aggregation of magnetic nanoparticles |
| CA2434604C (en) | 2001-02-12 | 2010-09-28 | Immunivest Corporation | Cartridge for containing a specimen sample for optical analysis |
| WO2003019141A2 (en) * | 2001-08-23 | 2003-03-06 | Immunivest Corporation | Analysis of circulating tumor cells, fragments, and debris |
| GB2395270B (en) * | 2002-11-14 | 2006-08-16 | Univ Nottingham | Tumour marker proteins and uses thereof |
| JP4912894B2 (ja) * | 2004-02-19 | 2012-04-11 | イェール ユニバーシティー | プロテオーム技術を使用した癌タンパク質バイオマーカーの同定 |
| US20060024824A1 (en) * | 2004-07-16 | 2006-02-02 | Steven Woodside | Magnetic cell separation method |
| US7846743B2 (en) * | 2005-04-21 | 2010-12-07 | California Institute Of Technology | Uses of parylene membrane filters |
| EP2037265A1 (en) * | 2007-09-17 | 2009-03-18 | Adnagen AG | Solid phase cell isolation and/or enrichment method |
-
2012
- 2012-07-27 EP EP12746193.7A patent/EP2737317A2/en not_active Withdrawn
- 2012-07-27 US US14/235,185 patent/US20140295426A1/en not_active Abandoned
- 2012-07-27 TW TW101127107A patent/TW201312117A/zh unknown
- 2012-07-27 WO PCT/US2012/048452 patent/WO2013016600A2/en not_active Ceased
- 2012-07-27 JP JP2014523039A patent/JP2014521958A/ja active Pending
-
2014
- 2014-01-28 IL IL230687A patent/IL230687A0/en unknown
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63109793A (ja) * | 1986-10-28 | 1988-05-14 | Kyowa Hakko Kogyo Co Ltd | 抗ヒト中皮細胞単クロ−ン性抗体 |
| JPH09510779A (ja) * | 1994-03-10 | 1997-10-28 | フォドスタッド オイステイン | 特定化あるいは混合した細胞母集団または混合細胞母集団を含む溶液内の特定標的細胞を検出する方法および装置 |
| JP2008538509A (ja) * | 2005-04-21 | 2008-10-30 | カリフォルニア インスティチュート オブ テクノロジー | パリレンメンブレンフィルターの使用 |
| JP2009525478A (ja) * | 2006-01-31 | 2009-07-09 | ビオメリュー | 癌、特に乳癌、甲状腺癌及び肺癌のインビトロ診断のためのProNGFアッセイのための方法とProNGFの治療的使用 |
| JP2010501549A (ja) * | 2006-08-23 | 2010-01-21 | コリア リサーチ インスティテュート オブ バイオサイエンス アンド バイオテクノロジー | 胆管癌治療用薬学的組成物、胆管癌の成長または浸潤抑制方法、および胆管癌の治療方法 |
| WO2010102177A1 (en) * | 2009-03-06 | 2010-09-10 | Becton, Dickinson And Company | Glycodelin monoclonal antibodies and methods for their use in the detection of ovarian cancer |
Non-Patent Citations (2)
| Title |
|---|
| ERIC KIELHORN: "USE OF MAGNETIC ENRICHMENT FOR DETECTION OF CARCINOMA CELLS IN FLUID SPECIMENS", CANCER, vol. V94 N1, JPN5015000886, 1 January 2002 (2002-01-01), pages 205 - 211, ISSN: 0003313015 * |
| MASAHIRO HORIKAWA, ONCOLOGY REPORTS, vol. V25 N5, JPN5015000877, 18 February 2011 (2011-02-18), pages 1413 - 1420, ISSN: 0003313016 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2013016600A3 (en) | 2013-04-18 |
| EP2737317A2 (en) | 2014-06-04 |
| US20140295426A1 (en) | 2014-10-02 |
| TW201312117A (zh) | 2013-03-16 |
| IL230687A0 (en) | 2014-03-31 |
| WO2013016600A2 (en) | 2013-01-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2014521958A (ja) | 胸腔内液若しくは漿液と関連する腫瘍細胞の特徴づけによる癌の診断方法 | |
| JP5479355B2 (ja) | 血液中の循環黒色腫細胞の自動計数及び特徴付け | |
| JP4593557B2 (ja) | 循環腫瘍細胞(ctc):転移癌患者における増悪までの時間、生存および療法に対する応答の早期評価 | |
| US20140113310A9 (en) | Cancer detection markers | |
| US20070154960A1 (en) | Method for assessing disease states by profile analysis of isolated circulating endothelial cells | |
| WO2010065968A1 (en) | Cancer detection markers | |
| JP2008533487A (ja) | 循環腫瘍細胞を用いる転移性乳癌患者の療法中の各追跡期間ポイントでの無増悪および全生存を予測する方法 | |
| US20080113350A1 (en) | Blood test to monitor the genetic changes of progressive cancer using immunomagnetic enrichment and fluorescence in situ hybridization (FISH) | |
| JP2024023284A (ja) | がんのスクリーニング、診断、治療、及び再発における巨細胞の核酸の特徴付けの使用方法 | |
| Quirós‐Caso et al. | Routine flow cytometry approach for the evaluation of solid tumor neoplasms and immune cells in minimally invasive samples | |
| KR20190045200A (ko) | 방광암용 바이오마커로서의 케라틴 17 | |
| WO2005116264A2 (en) | A blood test to monitor the genetic changes of progressive cancer using immunomagnetic enrichment and fluorescence in situ hybridization (fish) | |
| Tkaczuk et al. | The significance of circulating epithelial cells in Breast Cancer patients by a novel negative selection method | |
| JP6707505B2 (ja) | 腫瘍細胞を検出するためのステロイド受容体アッセイ | |
| JP2012022002A (ja) | 循環腫瘍細胞を用いる転移性乳癌患者の療法中の各追跡期間ポイントでの無増悪および全生存を予測する方法 | |
| Slack et al. | Flow cytometric detection of ZAP-70 in chronic lymphocytic leukemia: correlation with immunocytochemistry and Western blot analysis | |
| WO2022030626A1 (ja) | 膀胱癌診断方法 | |
| WO2006020936A2 (en) | A method for assessing disease states by profile analysis of isolated circulating endothelial cells | |
| Xie et al. | Detection of circulating rare cells benefitted the diagnosis of malignant solitary pulmonary nodules | |
| BR102020026395A2 (pt) | Método, painel e kit para o diagnóstico e monitoramento do tratamento de pacientes com câncer de mama | |
| HK1190457A (en) | Steroid receptor assays for detecting tumor cells | |
| HK1195121B (en) | Steroid receptor assays for detecting tumor cells | |
| HK1195121A (en) | Steroid receptor assays for detecting tumor cells | |
| HK1148348B (en) | Automated enumeration and characterization of circulating melanoma cells in blood |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20150714 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20150714 |
|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20160427 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20160511 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20160725 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20170118 |