JP2014513036A5 - - Google Patents
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- Publication number
- JP2014513036A5 JP2014513036A5 JP2013536737A JP2013536737A JP2014513036A5 JP 2014513036 A5 JP2014513036 A5 JP 2014513036A5 JP 2013536737 A JP2013536737 A JP 2013536737A JP 2013536737 A JP2013536737 A JP 2013536737A JP 2014513036 A5 JP2014513036 A5 JP 2014513036A5
- Authority
- JP
- Japan
- Prior art keywords
- dmf
- diisopropylphosphorano
- rucl
- dimethylformamide
- benzene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013536737A JP5945545B2 (ja) | 2011-02-17 | 2012-02-16 | 光学活性なジヒドロベンゾフラン誘導体の製造法 |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011032610 | 2011-02-17 | ||
| JP2011032610 | 2011-02-17 | ||
| PCT/JP2012/054337 WO2012111849A1 (en) | 2011-02-17 | 2012-02-16 | Production method of optically active dihydrobenzofuran derivative |
| JP2013536737A JP5945545B2 (ja) | 2011-02-17 | 2012-02-16 | 光学活性なジヒドロベンゾフラン誘導体の製造法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014513036A JP2014513036A (ja) | 2014-05-29 |
| JP2014513036A5 true JP2014513036A5 (enExample) | 2015-04-02 |
| JP5945545B2 JP5945545B2 (ja) | 2016-07-05 |
Family
ID=45841559
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013536737A Expired - Fee Related JP5945545B2 (ja) | 2011-02-17 | 2012-02-16 | 光学活性なジヒドロベンゾフラン誘導体の製造法 |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US8952185B2 (enExample) |
| EP (1) | EP2675774A1 (enExample) |
| JP (1) | JP5945545B2 (enExample) |
| KR (1) | KR20140015371A (enExample) |
| CN (1) | CN103492348A (enExample) |
| AR (1) | AR085252A1 (enExample) |
| AU (1) | AU2012218401A1 (enExample) |
| BR (1) | BR112013020634A2 (enExample) |
| CA (1) | CA2827271A1 (enExample) |
| CL (1) | CL2013002356A1 (enExample) |
| CO (1) | CO6761376A2 (enExample) |
| CR (1) | CR20130407A (enExample) |
| DO (1) | DOP2013000188A (enExample) |
| EA (1) | EA201391180A1 (enExample) |
| EC (1) | ECSP13012855A (enExample) |
| IL (1) | IL227879A0 (enExample) |
| MA (1) | MA34965B1 (enExample) |
| MX (1) | MX2013009526A (enExample) |
| PH (1) | PH12013501718A1 (enExample) |
| SG (1) | SG192645A1 (enExample) |
| TN (1) | TN2013000347A1 (enExample) |
| TW (1) | TW201245169A (enExample) |
| UY (1) | UY33913A (enExample) |
| WO (1) | WO2012111849A1 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103145663B (zh) * | 2013-03-01 | 2016-03-23 | 上海高准医药有限公司 | (s)-2-(2,3-二氢苯并呋喃-3-基)乙酸衍生物，其制备方法及其在医药上的应用 |
| CN104250239B (zh) * | 2013-06-29 | 2016-09-07 | 山东轩竹医药科技有限公司 | 芳香多环羧酸衍生物 |
| CN104370864B (zh) * | 2013-08-14 | 2016-04-13 | 成都苑东生物制药股份有限公司 | 一种2-(6-羟基-2,3-二氢苯并呋喃-3-基)乙腈化合物和以该化合物制备tak-875药物的方法 |
| JP6533778B2 (ja) * | 2013-09-26 | 2019-06-19 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Ｇｐｒ４０アゴニストとしてのインダニルオキシジヒドロベンゾフラニル酢酸誘導体を調製するための方法および中間体 |
| CN105722841A (zh) | 2013-11-14 | 2016-06-29 | 卡迪拉保健有限公司 | 新型杂环化合物 |
| WO2015084692A1 (en) | 2013-12-04 | 2015-06-11 | Merck Sharp & Dohme Corp. | Antidiabetic bicyclic compounds |
| CN104177320B (zh) * | 2014-08-27 | 2016-03-02 | 广东东阳光药业有限公司 | 一种脲取代联苯类化合物及其组合物及用途 |
| US10561628B2 (en) * | 2015-03-19 | 2020-02-18 | Daiichi Sankyo Company, Limited | Solid preparation including antioxidant |
| BR112017019920B1 (pt) | 2015-03-19 | 2023-11-07 | Daiichi Sankyo Company, Limited | Preparação sólida farmacêutica, e, método para estabilização de uma preparação sólida farmacêutica |
| CN105418563B (zh) * | 2015-12-28 | 2017-11-10 | 山东大学 | Tak‑875类似物及其制备方法与应用 |
| CN107543872B (zh) * | 2016-06-29 | 2022-03-08 | 南京长澳医药科技有限公司 | 通过手性高效液相色谱法分离测定甲苯磺酸依度沙班水合物与其异构体杂质的方法 |
| CN110088089B (zh) | 2016-10-25 | 2023-08-29 | 勃林格殷格翰国际有限公司 | 苄基氨基吡啶基环丙烷甲酸、药物组合物及其用途 |
| US10919859B2 (en) | 2017-01-26 | 2021-02-16 | Boehringer Ingelheim International Gmbh | Benzylaminopyridylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof |
| BR102018007822A2 (pt) | 2017-04-20 | 2018-11-06 | Gilead Sciences, Inc. | composto, métodos para inibir pd-1, pd-l1 e/ou interação de pd-1/pd-l1 e para tratamento de câncer, composição farmacêutica, e, kit para tratamento de ou prevenção de câncer ou uma doença ou condição |
| CN106977478B (zh) * | 2017-04-21 | 2019-04-09 | 山东大学 | 一种2-(6-羟基-2,3-二氢苯并呋喃-3-基)乙酸甲酯的手性拆分方法 |
| WO2019160882A1 (en) | 2018-02-13 | 2019-08-22 | Gilead Sciences, Inc. | Pd-1/pd-l1 inhibitors |
| KR102591947B1 (ko) | 2018-04-19 | 2023-10-25 | 길리애드 사이언시즈, 인코포레이티드 | Pd-1/pd-l1 억제제 |
| PE20210642A1 (es) | 2018-07-13 | 2021-03-23 | Gilead Sciences Inc | Inhibidores de pd-1/pd-l1 |
| JP7312751B2 (ja) | 2018-07-30 | 2023-07-21 | 第一三共株式会社 | 安定化剤を含有する医薬品の固形製剤 |
| US11236085B2 (en) | 2018-10-24 | 2022-02-01 | Gilead Sciences, Inc. | PD-1/PD-L1 inhibitors |
| JP2022552655A (ja) | 2019-10-07 | 2022-12-19 | キャリーオペ，インク． | Ｇｐｒ１１９アゴニスト |
| MX2022010548A (es) | 2020-02-28 | 2022-09-23 | Kallyope Inc | Agonistas de gpr40. |
| MX2022014505A (es) | 2020-05-19 | 2022-12-13 | Kallyope Inc | Activadores de la ampk. |
| CA3183575A1 (en) | 2020-06-26 | 2021-12-30 | Iyassu Sebhat | Ampk activators |
| CN114539168B (zh) * | 2020-11-27 | 2023-11-17 | 武汉大学 | 一种合成Piragliatin及其类似物的方法 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1072649C (zh) | 1995-09-13 | 2001-10-10 | 武田药品工业株式会社 | 苯并氧杂吖庚因化合物,其生产方法和用途 |
| AR035016A1 (es) | 1999-08-25 | 2004-04-14 | Takeda Chemical Industries Ltd | Composicion de azol promotor de produccion/secrecion de neurotrofina, compuesto prodroga del mismo, composicion farmaceutica que lo comprende y uso del mismo para preparar esta ultima. |
| EP1302462A4 (en) | 2000-07-17 | 2007-07-18 | Takeda Pharmaceutical | SULFONATE DERIVATIVES, PROCESS FOR PRODUCTION AND USE THEREOF |
| BR0315815A (pt) | 2002-11-01 | 2005-09-13 | Takeda Pharmaceutical | Agentes para prevenir ou tratar neuropatia, para promover a produção ou a secreção de um fator neurotrópico, para melhorar a dor, neuroprotetor e farmacêutico, composto, métodos para prevenir ou tratar neuropatia e para promover a produção ou a secreção de um fator neurotrópico, para melhorar a dor para proteger um nervo em um mamìfero e para produzir um composto e uso de um composto |
| AU2003277576A1 (en) | 2002-11-08 | 2004-06-07 | Takeda Pharmaceutical Company Limited | Receptor function controlling agent |
| US20070004736A1 (en) | 2002-11-22 | 2007-01-04 | Keiji Kubo | Imidazole derivative, process for producing the same, and use |
| US7820837B2 (en) | 2003-05-30 | 2010-10-26 | Takeda Pharmaceutical Company Limited | Condensed ring compound |
| EP1669352A4 (en) | 2003-09-30 | 2008-12-17 | Takeda Pharmaceutical | THIAZOLINE DERIVATIVE AND ITS USE |
| WO2005058823A1 (ja) | 2003-12-17 | 2005-06-30 | Takeda Pharmaceutical Company Limited | ウレア誘導体、その製造法及び用途 |
| US7456218B2 (en) | 2003-12-25 | 2008-11-25 | Takeda Pharmaceutical Company Limited | 3-(4-benzyloxyphenyl) propanoic acid derivatives |
| WO2005063725A1 (ja) | 2003-12-26 | 2005-07-14 | Takeda Pharmaceutical Company Limited | フェニルプロパン酸誘導体 |
| WO2005087710A1 (ja) | 2004-03-15 | 2005-09-22 | Takeda Pharmaceutical Company Limited | アミノフェニルプロパン酸誘導体 |
| JP4859665B2 (ja) | 2004-03-30 | 2012-01-25 | 武田薬品工業株式会社 | アルコキシフェニルプロパン酸誘導体 |
| TWI396686B (zh) | 2004-05-21 | 2013-05-21 | Takeda Pharmaceutical | 環狀醯胺衍生物、以及其製品和用法 |
| GB0428101D0 (en) * | 2004-12-23 | 2005-01-26 | Astrazeneca Ab | Chemical Processes & Intermediates |
| US8957070B2 (en) | 2005-04-20 | 2015-02-17 | Takeda Pharmaceutical Company Limited | Glucokinase activator compounds, methods of activating glucokinase and methods of treating diabetes and obesity |
| EP1916234B1 (en) | 2005-07-29 | 2014-11-12 | Takeda Pharmaceutical Company Limited | Cyclopropanecarboxylic acid compound |
| US20090054435A1 (en) | 2005-07-29 | 2009-02-26 | Hiroshi Imoto | Phenoxyalkanoic Acid Compound |
| JP4094660B1 (ja) | 2005-08-10 | 2008-06-04 | 武田薬品工業株式会社 | 糖尿病治療剤 |
| JP2007063225A (ja) | 2005-09-01 | 2007-03-15 | Takeda Chem Ind Ltd | イミダゾピリジン化合物 |
| AU2007265966B2 (en) | 2006-06-27 | 2012-05-17 | Takeda Pharmaceutical Company Limited | Fused cyclic compounds |
| EP2298772A1 (en) | 2006-10-18 | 2011-03-23 | Takeda Pharmaceutical Company Limited | Fused heterocyclic compounds |
| CN101573357B (zh) | 2006-10-19 | 2013-01-23 | 武田药品工业株式会社 | 吲哚化合物 |
| WO2008093639A1 (ja) | 2007-01-29 | 2008-08-07 | Takeda Pharmaceutical Company Limited | ピラゾール化合物 |
| AU2008215490A1 (en) | 2007-02-09 | 2008-08-21 | Takeda Pharmaceutical Company Limited | Fused ring compounds as partial agonists of PPAR-gamma |
| US8455661B2 (en) | 2007-02-18 | 2013-06-04 | University Of Florida Research Foundation, Inc. | Catalysts containing N-heterocyclic carbenes for enantioselective synthesis |
| JPWO2008136428A1 (ja) | 2007-04-27 | 2010-07-29 | 武田薬品工業株式会社 | 含窒素５員複素環化合物 |
| EP2157859A4 (en) | 2007-06-19 | 2011-01-12 | Takeda Pharmaceutical | INDAZOL COMPOUNDS FOR THE ACTIVATION OF GLUCCOKINASE |
| US20120172351A1 (en) | 2009-06-09 | 2012-07-05 | Nobuyuki Negoro | Novel fused cyclic compound and use thereof |
| JP5129209B2 (ja) | 2009-08-03 | 2013-01-30 | ゴールドフラッグ株式会社 | ブラジャー及び該ブラジャー付き下着とこれをインナーとしたアウター |
-
2012
- 2012-02-16 UY UY0001033913A patent/UY33913A/es not_active Application Discontinuation
- 2012-02-16 CA CA2827271A patent/CA2827271A1/en not_active Abandoned
- 2012-02-16 SG SG2013059803A patent/SG192645A1/en unknown
- 2012-02-16 AU AU2012218401A patent/AU2012218401A1/en not_active Abandoned
- 2012-02-16 KR KR1020137024534A patent/KR20140015371A/ko not_active Withdrawn
- 2012-02-16 CN CN201280018878.7A patent/CN103492348A/zh active Pending
- 2012-02-16 EP EP12709184.1A patent/EP2675774A1/en not_active Withdrawn
- 2012-02-16 JP JP2013536737A patent/JP5945545B2/ja not_active Expired - Fee Related
- 2012-02-16 MX MX2013009526A patent/MX2013009526A/es not_active Application Discontinuation
- 2012-02-16 US US13/985,395 patent/US8952185B2/en not_active Expired - Fee Related
- 2012-02-16 PH PH1/2013/501718A patent/PH12013501718A1/en unknown
- 2012-02-16 AR ARP120100517A patent/AR085252A1/es not_active Application Discontinuation
- 2012-02-16 MA MA36243A patent/MA34965B1/fr unknown
- 2012-02-16 BR BR112013020634A patent/BR112013020634A2/pt not_active IP Right Cessation
- 2012-02-16 TW TW101105030A patent/TW201245169A/zh unknown
- 2012-02-16 EA EA201391180A patent/EA201391180A1/ru unknown
- 2012-02-16 WO PCT/JP2012/054337 patent/WO2012111849A1/en not_active Ceased
-
2013
- 2013-08-08 IL IL227879A patent/IL227879A0/en unknown
- 2013-08-14 CL CL2013002356A patent/CL2013002356A1/es unknown
- 2013-08-15 DO DO2013000188A patent/DOP2013000188A/es unknown
- 2013-08-16 TN TNP2013000347A patent/TN2013000347A1/fr unknown
- 2013-08-23 CR CR20130407A patent/CR20130407A/es not_active Application Discontinuation
- 2013-08-28 EC ECSP13012855 patent/ECSP13012855A/es unknown
- 2013-09-17 CO CO13220813A patent/CO6761376A2/es unknown