JP2014513036A5 - - Google Patents
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- Publication number
- JP2014513036A5 JP2014513036A5 JP2013536737A JP2013536737A JP2014513036A5 JP 2014513036 A5 JP2014513036 A5 JP 2014513036A5 JP 2013536737 A JP2013536737 A JP 2013536737A JP 2013536737 A JP2013536737 A JP 2013536737A JP 2014513036 A5 JP2014513036 A5 JP 2014513036A5
- Authority
- JP
- Japan
- Prior art keywords
- dmf
- diisopropylphosphorano
- rucl
- dimethylformamide
- benzene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 claims 3
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 claims 3
- 239000012327 Ruthenium complex Substances 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013536737A JP5945545B2 (ja) | 2011-02-17 | 2012-02-16 | 光学活性なジヒドロベンゾフラン誘導体の製造法 |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011032610 | 2011-02-17 | ||
| JP2011032610 | 2011-02-17 | ||
| PCT/JP2012/054337 WO2012111849A1 (en) | 2011-02-17 | 2012-02-16 | Production method of optically active dihydrobenzofuran derivative |
| JP2013536737A JP5945545B2 (ja) | 2011-02-17 | 2012-02-16 | 光学活性なジヒドロベンゾフラン誘導体の製造法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014513036A JP2014513036A (ja) | 2014-05-29 |
| JP2014513036A5 true JP2014513036A5 (enExample) | 2015-04-02 |
| JP5945545B2 JP5945545B2 (ja) | 2016-07-05 |
Family
ID=45841559
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013536737A Expired - Fee Related JP5945545B2 (ja) | 2011-02-17 | 2012-02-16 | 光学活性なジヒドロベンゾフラン誘導体の製造法 |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US8952185B2 (enExample) |
| EP (1) | EP2675774A1 (enExample) |
| JP (1) | JP5945545B2 (enExample) |
| KR (1) | KR20140015371A (enExample) |
| CN (1) | CN103492348A (enExample) |
| AR (1) | AR085252A1 (enExample) |
| AU (1) | AU2012218401A1 (enExample) |
| BR (1) | BR112013020634A2 (enExample) |
| CA (1) | CA2827271A1 (enExample) |
| CL (1) | CL2013002356A1 (enExample) |
| CO (1) | CO6761376A2 (enExample) |
| CR (1) | CR20130407A (enExample) |
| DO (1) | DOP2013000188A (enExample) |
| EA (1) | EA201391180A1 (enExample) |
| EC (1) | ECSP13012855A (enExample) |
| IL (1) | IL227879A0 (enExample) |
| MA (1) | MA34965B1 (enExample) |
| MX (1) | MX2013009526A (enExample) |
| PH (1) | PH12013501718A1 (enExample) |
| SG (1) | SG192645A1 (enExample) |
| TN (1) | TN2013000347A1 (enExample) |
| TW (1) | TW201245169A (enExample) |
| UY (1) | UY33913A (enExample) |
| WO (1) | WO2012111849A1 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103145663B (zh) * | 2013-03-01 | 2016-03-23 | 上海高准医药有限公司 | (s)-2-(2,3-二氢苯并呋喃-3-基)乙酸衍生物，其制备方法及其在医药上的应用 |
| CN104250239B (zh) * | 2013-06-29 | 2016-09-07 | 山东轩竹医药科技有限公司 | 芳香多环羧酸衍生物 |
| CN104370864B (zh) * | 2013-08-14 | 2016-04-13 | 成都苑东生物制药股份有限公司 | 一种2-(6-羟基-2,3-二氢苯并呋喃-3-基)乙腈化合物和以该化合物制备tak-875药物的方法 |
| WO2015044073A1 (en) * | 2013-09-26 | 2015-04-02 | Boehringer Ingelheim International Gmbh | Process and intermediates for preparing indanyloxydihydrobenzofuranyl acetic acid derivatives as gpr40 agonists |
| US10011609B2 (en) | 2013-11-14 | 2018-07-03 | Cadila Healthcare Limited | Heterocyclic compounds |
| US9957219B2 (en) | 2013-12-04 | 2018-05-01 | Merck Sharp & Dohme Corp. | Antidiabetic bicyclic compounds |
| CN104177320B (zh) * | 2014-08-27 | 2016-03-02 | 广东东阳光药业有限公司 | 一种脲取代联苯类化合物及其组合物及用途 |
| EP3513788B1 (en) | 2015-03-19 | 2020-07-29 | Daiichi Sankyo Company, Limited | Solid preparation containing colorant |
| EP3272345B1 (en) * | 2015-03-19 | 2019-10-16 | Daiichi Sankyo Company, Limited | Solid preparation containing antioxidant agent |
| CN105418563B (zh) * | 2015-12-28 | 2017-11-10 | 山东大学 | Tak‑875类似物及其制备方法与应用 |
| CN107543872B (zh) * | 2016-06-29 | 2022-03-08 | 南京长澳医药科技有限公司 | 通过手性高效液相色谱法分离测定甲苯磺酸依度沙班水合物与其异构体杂质的方法 |
| US10538490B2 (en) | 2016-10-25 | 2020-01-21 | Boehringer Ingelheim International Gmbh | Benzylaminopyridylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof |
| WO2018138027A1 (en) | 2017-01-26 | 2018-08-02 | Boehringer Ingelheim International Gmbh | Benzylaminopyridylcyclopropanecarboxylic acids, pharmaceuticalcompositions and uses thereof |
| CN106977478B (zh) * | 2017-04-21 | 2019-04-09 | 山东大学 | 一种2-(6-羟基-2,3-二氢苯并呋喃-3-基)乙酸甲酯的手性拆分方法 |
| UA126458C2 (uk) | 2018-02-13 | 2022-10-05 | Гіліад Сайєнсіз, Інк. | Інгібітори pd-1/pd-l1 |
| US10899735B2 (en) | 2018-04-19 | 2021-01-26 | Gilead Sciences, Inc. | PD-1/PD-L1 inhibitors |
| EP3820572B1 (en) | 2018-07-13 | 2023-08-16 | Gilead Sciences, Inc. | Pd-1/pd-l1 inhibitors |
| CN118286172A (zh) | 2018-07-30 | 2024-07-05 | 第一三共株式会社 | 含有稳定剂的固体药物制剂 |
| AU2019366355B2 (en) | 2018-10-24 | 2022-10-13 | Gilead Sciences, Inc. | PD-1/PD-L1 inhibitors |
| WO2021071837A1 (en) | 2019-10-07 | 2021-04-15 | Kallyope, Inc. | Gpr119 agonists |
| TW202140440A (zh) | 2020-02-28 | 2021-11-01 | 美商克力歐普股份有限公司 | Gpr40激動劑 |
| UY39222A (es) | 2020-05-19 | 2021-11-30 | Kallyope Inc | Activadores de la ampk |
| AU2021297323A1 (en) | 2020-06-26 | 2023-02-16 | Kallyope, Inc. | AMPK activators |
| CN114539168B (zh) * | 2020-11-27 | 2023-11-17 | 武汉大学 | 一种合成Piragliatin及其类似物的方法 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU6944296A (en) | 1995-09-13 | 1997-04-01 | Takeda Chemical Industries Ltd. | Benzoxazepine compounds, their production and use as lipid lowering agents |
| AR035016A1 (es) | 1999-08-25 | 2004-04-14 | Takeda Chemical Industries Ltd | Composicion de azol promotor de produccion/secrecion de neurotrofina, compuesto prodroga del mismo, composicion farmaceutica que lo comprende y uso del mismo para preparar esta ultima. |
| EP1302462A4 (en) | 2000-07-17 | 2007-07-18 | Takeda Pharmaceutical | SULFONATE DERIVATIVES, PROCESS FOR PRODUCTION AND USE THEREOF |
| CA2504511A1 (en) | 2002-11-01 | 2004-05-13 | Takeda Pharmaceutical Company Limited | Agent for preventing or treating neuropathy |
| EP1559422B1 (en) | 2002-11-08 | 2014-04-30 | Takeda Pharmaceutical Company Limited | Receptor function controlling agent |
| EP1564213A4 (en) | 2002-11-22 | 2009-05-27 | Takeda Pharmaceutical | IMIDAZOLE DERIVATIVE, METHOD FOR THE PRODUCTION AND USE THEREOF |
| WO2004106276A1 (ja) | 2003-05-30 | 2004-12-09 | Takeda Pharmaceutical Company Limited | 縮合環化合物 |
| US7534887B2 (en) | 2003-09-30 | 2009-05-19 | Takeda Pharmaceutical Company Limited | Thiazoline derivative and use of the same |
| CA2550012A1 (en) | 2003-12-17 | 2005-06-30 | Takeda Pharmaceutical Company Limited | Urea derivative, process for producing the same and use |
| RU2006126978A (ru) | 2003-12-25 | 2008-01-27 | Такеда Фармасьютикал Компани Лимитед (Jp) | Производные 3-(4-бензилоксифенил)пропановой кислоты |
| JP4855777B2 (ja) | 2003-12-26 | 2012-01-18 | 武田薬品工業株式会社 | フェニルプロパン酸誘導体 |
| WO2005087710A1 (ja) | 2004-03-15 | 2005-09-22 | Takeda Pharmaceutical Company Limited | アミノフェニルプロパン酸誘導体 |
| JP4859665B2 (ja) | 2004-03-30 | 2012-01-25 | 武田薬品工業株式会社 | アルコキシフェニルプロパン酸誘導体 |
| TWI396686B (zh) | 2004-05-21 | 2013-05-21 | Takeda Pharmaceutical | 環狀醯胺衍生物、以及其製品和用法 |
| GB0428101D0 (en) * | 2004-12-23 | 2005-01-26 | Astrazeneca Ab | Chemical Processes & Intermediates |
| JP5094394B2 (ja) | 2005-04-20 | 2012-12-12 | 武田薬品工業株式会社 | 縮合複素環化合物 |
| WO2007013694A1 (ja) | 2005-07-29 | 2007-02-01 | Takeda Pharmaceutical Company Limited | フェノキシアルカン酸化合物 |
| WO2007013689A1 (ja) | 2005-07-29 | 2007-02-01 | Takeda Pharmaceutical Company Limited | シクロプロパンカルボン酸化合物 |
| PE20070338A1 (es) | 2005-08-10 | 2007-04-16 | Takeda Pharmaceutical | Derivados heterociclicos como agentes terapeuticos para diabetes |
| JP2007063225A (ja) | 2005-09-01 | 2007-03-15 | Takeda Chem Ind Ltd | イミダゾピリジン化合物 |
| RS53230B (sr) | 2006-06-27 | 2014-08-29 | Takeda Pharmaceutical Company Limited | Kondenzovana ciklična jedinjenja kao modulatori gpr40 receptora |
| JP5306818B2 (ja) | 2006-10-18 | 2013-10-02 | 武田薬品工業株式会社 | 縮合複素環化合物 |
| AU2007310064B2 (en) | 2006-10-19 | 2013-03-28 | Takeda Pharmaceutical Company Limited | Indole compound |
| WO2008093639A1 (ja) | 2007-01-29 | 2008-08-07 | Takeda Pharmaceutical Company Limited | ピラゾール化合物 |
| MX2009008103A (es) | 2007-02-09 | 2009-08-18 | Takeda Pharmaceutical | Compuestos anulares fusionados como agonistas parciales de prar-gamma. |
| WO2008101197A1 (en) | 2007-02-18 | 2008-08-21 | University Of Florida Research Foundation, Inc. | Catalysts containing n-heterocyclic carbenes for enantioselective synthesis |
| JPWO2008136428A1 (ja) | 2007-04-27 | 2010-07-29 | 武田薬品工業株式会社 | 含窒素５員複素環化合物 |
| EP2157859A4 (en) | 2007-06-19 | 2011-01-12 | Takeda Pharmaceutical | INDAZOL COMPOUNDS FOR THE ACTIVATION OF GLUCCOKINASE |
| JP5657578B2 (ja) | 2009-06-09 | 2015-01-21 | 武田薬品工業株式会社 | 新規な縮合環化合物およびその用途 |
| JP5129209B2 (ja) | 2009-08-03 | 2013-01-30 | ゴールドフラッグ株式会社 | ブラジャー及び該ブラジャー付き下着とこれをインナーとしたアウター |
-
2012
- 2012-02-16 KR KR1020137024534A patent/KR20140015371A/ko not_active Withdrawn
- 2012-02-16 AU AU2012218401A patent/AU2012218401A1/en not_active Abandoned
- 2012-02-16 CN CN201280018878.7A patent/CN103492348A/zh active Pending
- 2012-02-16 JP JP2013536737A patent/JP5945545B2/ja not_active Expired - Fee Related
- 2012-02-16 EA EA201391180A patent/EA201391180A1/ru unknown
- 2012-02-16 PH PH1/2013/501718A patent/PH12013501718A1/en unknown
- 2012-02-16 MA MA36243A patent/MA34965B1/fr unknown
- 2012-02-16 UY UY0001033913A patent/UY33913A/es not_active Application Discontinuation
- 2012-02-16 EP EP12709184.1A patent/EP2675774A1/en not_active Withdrawn
- 2012-02-16 MX MX2013009526A patent/MX2013009526A/es not_active Application Discontinuation
- 2012-02-16 CA CA2827271A patent/CA2827271A1/en not_active Abandoned
- 2012-02-16 BR BR112013020634A patent/BR112013020634A2/pt not_active IP Right Cessation
- 2012-02-16 WO PCT/JP2012/054337 patent/WO2012111849A1/en not_active Ceased
- 2012-02-16 US US13/985,395 patent/US8952185B2/en not_active Expired - Fee Related
- 2012-02-16 TW TW101105030A patent/TW201245169A/zh unknown
- 2012-02-16 SG SG2013059803A patent/SG192645A1/en unknown
- 2012-02-16 AR ARP120100517A patent/AR085252A1/es not_active Application Discontinuation
-
2013
- 2013-08-08 IL IL227879A patent/IL227879A0/en unknown
- 2013-08-14 CL CL2013002356A patent/CL2013002356A1/es unknown
- 2013-08-15 DO DO2013000188A patent/DOP2013000188A/es unknown
- 2013-08-16 TN TNP2013000347A patent/TN2013000347A1/fr unknown
- 2013-08-23 CR CR20130407A patent/CR20130407A/es not_active Application Discontinuation
- 2013-08-28 EC ECSP13012855 patent/ECSP13012855A/es unknown
- 2013-09-17 CO CO13220813A patent/CO6761376A2/es unknown