JP2015504870A5 - - Google Patents
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- Publication number
- JP2015504870A5 JP2015504870A5 JP2014547526A JP2014547526A JP2015504870A5 JP 2015504870 A5 JP2015504870 A5 JP 2015504870A5 JP 2014547526 A JP2014547526 A JP 2014547526A JP 2014547526 A JP2014547526 A JP 2014547526A JP 2015504870 A5 JP2015504870 A5 JP 2015504870A5
- Authority
- JP
- Japan
- Prior art keywords
- angiotensin
- disorder
- derivative
- analog
- treating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- PVHLMTREZMEJCG-GDTLVBQBSA-N Ile(5)-angiotensin II (1-7) Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N1[C@@H](CCC1)C([O-])=O)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=[NH2+])NC(=O)[C@@H]([NH3+])CC([O-])=O)C(C)C)C1=CC=C(O)C=C1 PVHLMTREZMEJCG-GDTLVBQBSA-N 0.000 claims 1
- 108010021281 angiotensin I (1-7) Proteins 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000035475 disorder Diseases 0.000 claims 1
- 230000003176 fibrotic effect Effects 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161576673P | 2011-12-16 | 2011-12-16 | |
| US61/576,673 | 2011-12-16 | ||
| US201161579936P | 2011-12-23 | 2011-12-23 | |
| US61/579,936 | 2011-12-23 | ||
| PCT/US2012/069930 WO2013090833A1 (en) | 2011-12-16 | 2012-12-14 | Angiotensins for treatment of fibrosis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015504870A JP2015504870A (ja) | 2015-02-16 |
| JP2015504870A5 true JP2015504870A5 (enExample) | 2016-02-12 |
Family
ID=48613248
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014547526A Pending JP2015504870A (ja) | 2011-12-16 | 2012-12-14 | 線維症を処置するためのアンジオテンシン |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20150057216A1 (enExample) |
| EP (1) | EP2790716A4 (enExample) |
| JP (1) | JP2015504870A (enExample) |
| KR (1) | KR20150028761A (enExample) |
| CN (1) | CN104302305A (enExample) |
| AU (1) | AU2012351939A1 (enExample) |
| BR (1) | BR112014014674A2 (enExample) |
| CA (1) | CA2859573A1 (enExample) |
| WO (1) | WO2013090833A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LT1993360T (lt) | 2005-12-28 | 2017-06-12 | Vertex Pharmaceuticals Incorporated | N-[2,4-bis(1,1-dimetiletil)-5-hidroksifenil]-1,4-dihidro-4-oksochinolin-3-karboksamido kieta forma |
| AU2014268524A1 (en) * | 2013-05-24 | 2015-12-03 | Tarix Pharmaceuticals Ltd. | Angiotensin peptides in treating Marfan Syndrome and related disorders |
| WO2015002903A1 (en) | 2013-07-03 | 2015-01-08 | Arizona Board Of Regents For The University Of Arizona | Method for treating cognitive dysfunction |
| SG11201609593RA (en) * | 2014-05-16 | 2016-12-29 | Ultrast Inc | Phase-shifting formulations |
| JP6666899B2 (ja) | 2014-07-21 | 2020-03-18 | アリゾナ ボード オブ リージェンツ オン ビハーフ オブ ザ ユニヴァーシティー オブ アリゾナ | Ａｎｇ−（１−７）誘導体オリゴペプチド、ならびにそれを使用および作製するための方法 |
| US10183055B2 (en) | 2014-07-21 | 2019-01-22 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Ang-(1-7) derivative oligopeptides for the treatment of pain and other indications |
| EP3204358B1 (en) | 2014-10-07 | 2018-09-19 | Vertex Pharmaceuticals Incorporated | Co-crystals of modulators of cystic fibrosis transmembrane conductance regulator |
| MA41120A (fr) * | 2014-12-02 | 2017-10-10 | Afimmune Ltd | Compositions comprenant le 15-hepe et méthodes de traitement ou de prévention de la fibrose à l'aide de celles-ci |
| EP3328384B1 (en) | 2015-07-30 | 2020-07-29 | Monash University | Fibrotic treatment |
| JP2018530590A (ja) * | 2015-10-14 | 2018-10-18 | タリックス ファーマシューティカルズ リミテッド | 表皮水疱症の処置のための方法及び組成物 |
| WO2017218623A1 (en) * | 2016-06-14 | 2017-12-21 | Tarix Orphan Llc | Methods and compositions for the treatment of epidermolysis bullosa |
| US11331368B2 (en) | 2017-07-17 | 2022-05-17 | Monash University | Angiotensin receptor agonists and uses thereof |
| GB201913603D0 (en) | 2019-09-20 | 2019-11-06 | Vicore Pharma Ab | New compounds |
| WO2021164723A1 (en) * | 2020-02-20 | 2021-08-26 | Lee Sheau Long | Ginsenoside m1 as a modulator of angiotensin regulating enzymes and its use for treating diseases or conditions including symptoms caused by coronavirus |
| US20210315851A1 (en) | 2020-04-03 | 2021-10-14 | Afimmune Limited | Compositions comprising 15-hepe and methods of treating or preventing hematologic disorders, and/or related diseases |
| EP4085921A1 (en) * | 2021-05-04 | 2022-11-09 | CU-Pharmaceuticals UG | Angiotensin-(1-7) in the treatment of sars-cov related diseases |
| GB202201723D0 (en) | 2022-02-10 | 2022-03-30 | Vicore Pharma Ab | New use |
| WO2023152503A1 (en) | 2022-02-10 | 2023-08-17 | Vicore Pharma Ab | Use of buloxibutid for the treatment of idiopathic pulmonary fibrosis |
| WO2025050228A1 (es) * | 2023-09-08 | 2025-03-13 | Pontificia Universidad Católica De Chile | Composición farmacéutica que comprende un péptido o una combinación de péptidos agonistas de los receptores mas, at1 y at2 |
| KR102743940B1 (ko) | 2023-10-06 | 2024-12-19 | 엠브릭스 주식회사 | 안지오텐신 전환효소 2 및 Fc 절편을 포함하는 나노디스크 및 이의 용도 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU755225B2 (en) * | 1997-12-12 | 2002-12-05 | University Of Southern California | Wound healing compositions |
| YU78601A (sh) * | 1999-05-05 | 2005-07-19 | Aventis Pharma Deutschland Gmbh. | 1-(p-tienilbenzil)-imidazoli kao agonisti angiotenzin-(1-7)- receptora, postupak za njihovu proizvodnju, njihova primena i farmaceutski preparati koji ih sadrže |
| US7064127B2 (en) * | 2003-12-19 | 2006-06-20 | Mount Sinai School Of Medicine Of New York University | Treatment of hepatic fibrosis with imatinib mesylate |
| EP2163259B1 (en) * | 2008-09-12 | 2012-06-13 | Charité-Universitätsmedizin Berlin (Charité) | Use of an Ang-(1-7) receptor agonist in acute lung injury |
-
2012
- 2012-12-14 CA CA2859573A patent/CA2859573A1/en not_active Abandoned
- 2012-12-14 JP JP2014547526A patent/JP2015504870A/ja active Pending
- 2012-12-14 AU AU2012351939A patent/AU2012351939A1/en not_active Abandoned
- 2012-12-14 EP EP12857486.0A patent/EP2790716A4/en not_active Withdrawn
- 2012-12-14 US US14/365,565 patent/US20150057216A1/en not_active Abandoned
- 2012-12-14 WO PCT/US2012/069930 patent/WO2013090833A1/en not_active Ceased
- 2012-12-14 BR BR112014014674A patent/BR112014014674A2/pt not_active Application Discontinuation
- 2012-12-14 KR KR20147019878A patent/KR20150028761A/ko not_active Withdrawn
- 2012-12-14 CN CN201280069856.3A patent/CN104302305A/zh active Pending
-
2015
- 2015-11-23 US US14/948,985 patent/US20160074466A1/en not_active Abandoned
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