|
WO2008058035A1
(en)
*
|
2006-11-03 |
2008-05-15 |
Alphavax, Inc. |
Alphavirus and alphavirus replicon particle formulations and methods
|
|
US20090111099A1
(en)
*
|
2007-10-27 |
2009-04-30 |
Yongsheng Ma |
Promoter Detection and Analysis
|
|
US8067241B2
(en)
*
|
2009-08-26 |
2011-11-29 |
General Electric Company |
Method and apparatus for antigen retrieval process
|
|
ES2680915T3
(es)
|
2010-01-28 |
2018-09-11 |
The Children's Hospital Of Philadelphia |
Plataforma de fabricación escalable para la purificación de vectores virales y vectores virales purificados de este modo para su utilización en terapia génica
|
|
JP2013523175A
(ja)
|
2010-04-14 |
2013-06-17 |
イーエムディー・ミリポア・コーポレーション |
高力価、高純度のウイルスストックの作製方法及びその使用方法
|
|
WO2012018628A1
(en)
|
2010-07-26 |
2012-02-09 |
Board Of Regents, The University Of Texas System |
Methods for inducing an immune response via buccal and/or sublingual administration of a vaccine
|
|
US9879229B2
(en)
*
|
2011-03-14 |
2018-01-30 |
National Research Council Of Canada |
Method of viral production in cells
|
|
HK1202434A1
(en)
|
2011-11-22 |
2015-10-02 |
The Children's Hospital Of Philadelphia |
Virus vectors for highly efficient transgene delivery
|
|
PT2790737T
(pt)
|
2011-12-12 |
2019-02-28 |
Childrens Hospital Philadelphia |
Sistema de produção de vetores lentivirais a grande escala comercial e vetores produzidos pelo mesmo
|
|
US9974850B2
(en)
|
2013-01-25 |
2018-05-22 |
Board Of Regents, The University Of Texas System |
Immunogenic compositions and uses thereof
|
|
KR102219672B1
(ko)
*
|
2013-06-17 |
2021-02-25 |
드 슈타트 데르 네덜란덴, 베르테겐부어디그트 두어 드 미니스터 반 베이웨이에스, 미니스테리 반 폭스겐트존하이트, 벨지인 엔 스포츠 |
바이러스 성분의 어그리게이션을 저해하는 방법
|
|
CN105765066B
(zh)
*
|
2013-11-29 |
2018-12-14 |
宝生物工程株式会社 |
用于定量腺伴随病毒的方法
|
|
JP6730193B2
(ja)
|
2014-04-25 |
2020-07-29 |
ジェネトン |
高ビリルビン血症の処置
|
|
EP3151866B1
(en)
|
2014-06-09 |
2023-03-08 |
Voyager Therapeutics, Inc. |
Chimeric capsids
|
|
US10526583B2
(en)
|
2014-07-02 |
2020-01-07 |
University Of Florida Research Foundation, Incorporated |
Compositions and methods for purifying recombinant adeno-associated virus
|
|
CN107106689A
(zh)
|
2014-11-05 |
2017-08-29 |
沃雅戈治疗公司 |
用于治疗帕金森病的aadc多核苷酸
|
|
MX2017006217A
(es)
|
2014-11-14 |
2018-05-02 |
Voyager Therapeutics Inc |
Polinucleotidos moduladores.
|
|
IL292999A
(en)
|
2014-11-14 |
2022-07-01 |
Voyager Therapeutics Inc |
Compositions and methods of treating amyotrophic lateral sclerosis (als)
|
|
US11697825B2
(en)
|
2014-12-12 |
2023-07-11 |
Voyager Therapeutics, Inc. |
Compositions and methods for the production of scAAV
|
|
SG11201704919SA
(en)
|
2015-01-13 |
2017-07-28 |
Alfa Wassermann Inc |
Methods of purifying adeno-associated virus (aav) and/or recombinant adeno-associated virus (raav)
|
|
EP3054007A1
(en)
|
2015-02-09 |
2016-08-10 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Recombinant adeno-associated virus particle purification comprising an immuno-affinity purification step
|
|
US20180230489A1
(en)
|
2015-10-28 |
2018-08-16 |
Voyager Therapeutics, Inc. |
Regulatable expression using adeno-associated virus (aav)
|
|
JP7418957B2
(ja)
|
2015-11-16 |
2024-01-22 |
リサーチ インスティチュート アット ネイションワイド チルドレンズ ホスピタル |
タイチン系ミオパチー及び他のタイチノパチーの治療のための材料及び方法
|
|
ES2934848T3
(es)
*
|
2015-12-11 |
2023-02-27 |
Univ Pennsylvania |
Método de purificación escalable para AAV8
|
|
PT3436593T
(pt)
*
|
2016-03-28 |
2023-01-31 |
Ultragenyx Pharmaceutical Inc |
Métodos de inativação pelo calor de adenovírus
|
|
EP3448987A4
(en)
|
2016-04-29 |
2020-05-27 |
Voyager Therapeutics, Inc. |
COMPOSITIONS FOR TREATING A DISEASE
|
|
US11326182B2
(en)
|
2016-04-29 |
2022-05-10 |
Voyager Therapeutics, Inc. |
Compositions for the treatment of disease
|
|
MX2018014154A
(es)
|
2016-05-18 |
2019-05-06 |
Voyager Therapeutics Inc |
Polinucleotidos moduladores.
|
|
EP3458589A4
(en)
|
2016-05-18 |
2020-01-01 |
Voyager Therapeutics, Inc. |
COMPOSITIONS AND METHODS FOR TREATING MORBUS HUNTINGTON
|
|
AU2017299779B2
(en)
*
|
2016-07-21 |
2021-12-02 |
Spark Therapeutics, Inc. |
Scalable high recovery methods for producing high yield recombinant adeno-associated viral (rAAV) vector and recombinant adeno-associated viral (rAAV) vectors produced thereby
|
|
US20190185864A1
(en)
|
2016-08-23 |
2019-06-20 |
Akouos, Inc. |
Compositions and methods for treating non-age-associated hearing impairment in a human subject
|
|
JP2019531787A
(ja)
|
2016-08-30 |
2019-11-07 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
生物医学的ターゲティング及びデリバリーの方法並びにそれを実行するための装置及びシステム
|
|
EP3293203A1
(en)
|
2016-09-12 |
2018-03-14 |
Genethon |
Acid-alpha glucosidase variants and uses thereof
|
|
EP3293260A1
(en)
|
2016-09-12 |
2018-03-14 |
Genethon |
Acid-alpha glucosidase variants and uses thereof
|
|
EP3293259A1
(en)
|
2016-09-12 |
2018-03-14 |
Genethon |
Acid-alpha glucosidase variants and uses thereof
|
|
SG11201901494UA
(en)
|
2016-09-12 |
2019-03-28 |
Genethon |
Acid-alpha glucosidase variants and uses thereof
|
|
CN109952372A
(zh)
|
2016-09-16 |
2019-06-28 |
白血球保健股份有限公司 |
获得有效用于疫苗接种或基因治疗的基于病毒载体的组合物的新方法
|
|
JP7545210B2
(ja)
*
|
2016-11-04 |
2024-09-04 |
武田薬品工業株式会社 |
アデノ随伴ウイルス製剤
|
|
US10626376B2
(en)
|
2016-11-14 |
2020-04-21 |
St. Jude Children's Research Hospital |
Method for isolating and purifying adeno-associated virus particles using salt
|
|
US10294452B2
(en)
*
|
2016-11-22 |
2019-05-21 |
Dao-Yao He |
Lysis, extraction and purification of adeno-associated virus and adenovirus from host cells
|
|
EP3576796A1
(en)
|
2017-02-01 |
2019-12-11 |
Centre National De La Recherche Scientifique |
Particles and compositions comprising the same for transfection
|
|
US11541131B2
(en)
|
2017-03-10 |
2023-01-03 |
Genethon |
Treatment of glycogen storage disease III
|
|
CN119491003A
(zh)
|
2017-05-05 |
2025-02-21 |
沃雅戈治疗公司 |
治疗亨廷顿病的组合物和方法
|
|
EP3618839A4
(en)
|
2017-05-05 |
2021-06-09 |
Voyager Therapeutics, Inc. |
Compositions and methods of treating amyotrophic lateral sclerosis (als)
|
|
JOP20190269A1
(ar)
|
2017-06-15 |
2019-11-20 |
Voyager Therapeutics Inc |
بولي نوكليوتيدات aadc لعلاج مرض باركنسون
|
|
CA3070087A1
(en)
|
2017-07-17 |
2019-01-24 |
Voyager Therapeutics, Inc. |
Trajectory array guide system
|
|
EP3662060A2
(en)
|
2017-08-03 |
2020-06-10 |
Voyager Therapeutics, Inc. |
Compositions and methods for delivery of aav
|
|
EP3687582A4
(en)
|
2017-09-29 |
2021-07-14 |
Voyager Therapeutics, Inc. |
RESCUE OF CENTRAL AND PERIPHERAL NEUROLOGICAL PHENOTYPE OF FRIEDREICH ATAXIA BY INTRAVENOUS ADMINISTRATION
|
|
CN111479924B
(zh)
|
2017-10-16 |
2024-06-14 |
沃雅戈治疗公司 |
肌萎缩性侧索硬化症(als)的治疗
|
|
EP4454654A3
(en)
|
2017-10-16 |
2025-02-19 |
Voyager Therapeutics, Inc. |
Treatment of amyotrophic lateral sclerosis (als)
|
|
MX2020004830A
(es)
|
2017-11-08 |
2020-11-11 |
Avexis Inc |
Medios y metodo para preparar vectores virales y usos de los mismos.
|
|
EP3720500A4
(en)
*
|
2017-12-05 |
2021-08-25 |
Applied Genetic Technologies Corporation |
FORMULATION OPTIMIZATION FOR VIRAL PARTICLES
|
|
IL275880B2
(en)
|
2018-01-31 |
2025-10-01 |
Res Inst Nationwide Childrens Hospital |
Gene therapy for brachioradial muscular dystrophy type 2C
|
|
WO2019154939A1
(en)
|
2018-02-07 |
2019-08-15 |
Genethon |
Hybrid regulatory elements
|
|
WO2019173434A1
(en)
|
2018-03-06 |
2019-09-12 |
Voyager Therapeutics, Inc. |
Insect cell manufactured partial self-complementary aav genomes
|
|
WO2019210137A1
(en)
|
2018-04-27 |
2019-10-31 |
Voyager Therapeutics, Inc. |
Methods for measuring the potency of aadc viral vectors
|
|
JP2021523914A
(ja)
|
2018-05-15 |
2021-09-09 |
ボイジャー セラピューティクス インコーポレイテッドVoyager Therapeutics,Inc. |
パーキンソン病を治療するための組成物および方法
|
|
WO2019222444A2
(en)
|
2018-05-16 |
2019-11-21 |
Voyager Therapeutics, Inc. |
Directed evolution
|
|
US20210207167A1
(en)
|
2018-05-16 |
2021-07-08 |
Voyager Therapeutics, Inc. |
Aav serotypes for brain specific payload delivery
|
|
CN120718958A
(zh)
|
2018-06-08 |
2025-09-30 |
诺华股份有限公司 |
用于测量药物产品效力的基于细胞的测定
|
|
BR112020026853A2
(pt)
|
2018-06-29 |
2021-04-20 |
Research Institute At Nationwide Children's Hospital |
produtos de vírus adeno-associados recombinantes e métodos para tratar a distrofia muscular de cinturas tipo 2a
|
|
BR112020026361A2
(pt)
*
|
2018-06-29 |
2021-03-30 |
Wuhan Neurophth Biotechnology Limited Company |
Composições e métodos para tratar neuropatia óptica hereditária de leber
|
|
WO2020010042A1
(en)
|
2018-07-02 |
2020-01-09 |
Voyager Therapeutics, Inc. |
Treatment of amyotrophic lateral sclerosis and disorders associated with the spinal cord
|
|
US20210163990A1
(en)
*
|
2018-07-11 |
2021-06-03 |
Baxalta Incorporated |
Aav compositions
|
|
AU2019310459A1
(en)
|
2018-07-24 |
2021-02-18 |
Voyager Therapeutics, Inc. |
Systems and methods for producing gene therapy formulations
|
|
ES2946415T3
(es)
|
2018-08-08 |
2023-07-18 |
Genethon |
Mini-GDE para el tratamiento de la enfermedad de almacenamiento de glucógeno III
|
|
EP3833745A1
(en)
*
|
2018-08-10 |
2021-06-16 |
REGENXBIO Inc. |
Scalable method for recombinant aav production
|
|
EP3840785A4
(en)
|
2018-08-20 |
2022-07-13 |
Wuhan Neurophth Biotechnology Limited Company |
COMPOSITIONS AND METHODS FOR THE TREATMENT OF LEBERIAN OPTIC ATROPHY
|
|
JP7528066B2
(ja)
|
2018-09-28 |
2024-08-05 |
ボイジャー セラピューティクス インコーポレイテッド |
操作されたプロモータを有するフラタキシン発現コンストラクトおよびその使用方法
|
|
US20210348242A1
(en)
|
2018-10-04 |
2021-11-11 |
Voyager Therapeutics, Inc. |
Methods for measuring the titer and potency of viral vector particles
|
|
SG11202107645RA
(en)
|
2019-01-18 |
2021-08-30 |
Voyager Therapeutics Inc |
Methods and systems for producing aav particles
|
|
JP2022521776A
(ja)
|
2019-02-26 |
2022-04-12 |
リサーチ インスティチュート アット ネイションワイド チルドレンズ ホスピタル |
Β-サルコグリカンのアデノ随伴ウイルスベクター送達および筋ジストロフィーの治療
|
|
JP7541027B2
(ja)
|
2019-04-08 |
2024-08-27 |
ジェネトン |
筋肉発現のためのハイブリッドプロモーター
|
|
CN113993552A
(zh)
*
|
2019-04-19 |
2022-01-28 |
再生生物股份有限公司 |
腺相关病毒载体制剂和方法
|
|
CN113692411A
(zh)
|
2019-04-19 |
2021-11-23 |
吉尼松公司 |
成纤维细胞生长因子23相关的低磷酸盐血症的基因治疗
|
|
TW202106879A
(zh)
|
2019-04-29 |
2021-02-16 |
美商航海家醫療公司 |
於生物反應器中生產經桿狀病毒感染之昆蟲細胞(biic)之系統及方法
|
|
CN120137971A
(zh)
|
2019-07-25 |
2025-06-13 |
诺华股份有限公司 |
可调节的表达系统
|
|
EP4010465A1
(en)
|
2019-08-09 |
2022-06-15 |
Voyager Therapeutics, Inc. |
Cell culture medium for use in producing gene therapy products in bioreactors
|
|
WO2021028559A1
(en)
|
2019-08-14 |
2021-02-18 |
Leukocare Ag |
Method for obtaining efficient compositions comprising viral vectors for vaccination or gene therapy
|
|
US11155835B2
(en)
|
2019-08-19 |
2021-10-26 |
The Catholic University Of America |
Prokaryotic-eukaryotic hybrid viral vector for delivery of large cargos of genes and proteins into human cells
|
|
US11401530B2
(en)
|
2019-08-19 |
2022-08-02 |
The Catholic University Of America |
Bacteriophage-based artificial viruses for human genome remodeling
|
|
AU2020331987B2
(en)
|
2019-08-21 |
2025-10-16 |
Research Institute At Nationwide Children's Hospital |
Adeno-associated virus vector delivery of alpha-sarcoglycan and the treatment of muscular dystrophy
|
|
TW202122582A
(zh)
|
2019-08-26 |
2021-06-16 |
美商航海家醫療公司 |
病毒蛋白之控制表現
|
|
CA3156984A1
(en)
|
2019-10-07 |
2021-04-15 |
Regenxbio Inc. |
Adeno-associated virus vector pharmaceutical composition and methods
|
|
WO2021078834A1
(en)
|
2019-10-22 |
2021-04-29 |
Genethon |
Chimeric acid-alpha glucosidase polypeptides and uses thereof
|
|
CN114555808A
(zh)
|
2019-10-22 |
2022-05-27 |
吉尼松公司 |
嵌合多肽及其用途
|
|
CN113025633B
(zh)
|
2019-12-09 |
2024-08-27 |
武汉纽福斯生物科技有限公司 |
编码人nadh脱氢酶亚单位1蛋白的核酸及其应用
|
|
KR102167829B1
(ko)
*
|
2020-02-10 |
2020-10-20 |
주식회사 이노테라피 |
아데노연관바이러스용 안정화제 및 이를 이용한 아데노연관바이러스의 안정화 방법
|
|
CN116096905A
(zh)
|
2020-02-21 |
2023-05-09 |
阿库斯股份有限公司 |
用于治疗人受试者的非年龄相关性听力损伤的组合物和方法
|
|
WO2021236908A2
(en)
|
2020-05-20 |
2021-11-25 |
Biomarin Pharmaceutical Inc. |
Use of regulatory proteins for the production of adeno-associated virus
|
|
EP3913060A1
(en)
|
2020-05-22 |
2021-11-24 |
Genethon |
Vectors encoding a glucose-6-phosphatase (g6pase-a) for gene therapy
|
|
JP2023528406A
(ja)
*
|
2020-06-02 |
2023-07-04 |
ヤンセン バイオテツク,インコーポレーテツド |
ウイルス精製のための材料及び方法
|
|
WO2022032153A1
(en)
|
2020-08-06 |
2022-02-10 |
Voyager Therapeutics, Inc. |
Cell culture medium for use in producing gene therapy products in bioreactors
|
|
US20220040305A1
(en)
*
|
2020-08-07 |
2022-02-10 |
Janssen Biotech, Inc. |
Formulations for highly purified viral particles
|
|
EP4200410A1
(en)
|
2020-08-24 |
2023-06-28 |
Genethon |
C-terminal truncated gde for the treatment of glycogen storage disease iii
|
|
IL302128A
(en)
|
2020-11-02 |
2023-06-01 |
Biomarin Pharm Inc |
A process for the enrichment of adeno-associated virus
|
|
WO2022122883A1
(en)
|
2020-12-09 |
2022-06-16 |
Genethon |
Lysosomal acid lipase variants and uses thereof
|
|
US20240141378A1
(en)
|
2021-03-03 |
2024-05-02 |
Voyager Therapeutics, Inc. |
Controlled expression of viral proteins
|
|
WO2022187473A2
(en)
|
2021-03-03 |
2022-09-09 |
Voyager Therapeutics, Inc. |
Controlled expression of viral proteins
|
|
WO2022236008A1
(en)
*
|
2021-05-07 |
2022-11-10 |
Board Of Regents, The University Of Texas System |
Methods and compositions for transport, storage, and delivery of adeno-associated viral vector and other molecules
|
|
US20240350670A1
(en)
|
2021-08-04 |
2024-10-24 |
Genethon |
Hybrid promoters for gene expression in muscles and in the cns
|
|
CN117980484A
(zh)
|
2021-09-16 |
2024-05-03 |
诺华股份有限公司 |
新颖的转录因子
|
|
US12285497B2
(en)
|
2021-10-15 |
2025-04-29 |
Research Institute At Nationwide Children's Hospital |
Self-complementary adeno-associated virus vector and its use in treatment of muscular dystrophy
|
|
JP2024539123A
(ja)
|
2021-10-25 |
2024-10-28 |
ノバルティス アーゲー |
アデノ随伴ウイルス(aav)送達を改善する方法
|
|
EP4511392A1
(en)
|
2022-03-17 |
2025-02-26 |
Innoskel |
Polynucleotides encoding the alpha-1 chain of human type ii collagen and methods of their use
|
|
WO2023175585A1
(en)
|
2022-03-17 |
2023-09-21 |
Innoskel |
Hybrid promoters and their use in osteolysis syndrome
|
|
WO2023214346A1
(en)
|
2022-05-06 |
2023-11-09 |
Novartis Ag |
Novel recombinant aav vp2 fusion polypeptides
|
|
EP4536816A1
(en)
|
2022-06-09 |
2025-04-16 |
Genethon |
N-terminal truncated gde for the treatment of glycogen storage disease iii
|
|
WO2024054983A1
(en)
|
2022-09-08 |
2024-03-14 |
Voyager Therapeutics, Inc. |
Controlled expression of viral proteins
|
|
TW202426017A
(zh)
*
|
2022-11-24 |
2024-07-01 |
俄羅斯聯邦商拜奧卡德聯合股份公司 |
非包膜病毒的藥物組合物
|
|
CN121420060A
(zh)
|
2023-06-29 |
2026-01-27 |
吉尼松公司 |
用于治疗糖原贮积病iii的n-端截短的糖原脱支酶
|
|
EP4606892A1
(en)
|
2024-02-23 |
2025-08-27 |
Merck Patent GmbH |
Methods for the production of viral particles
|