|
CA2668417A1
(en)
*
|
2006-11-03 |
2008-05-15 |
Alphavax, Inc. |
Alphavirus and alphavirus replicon particle formulations and methods
|
|
US20090111099A1
(en)
*
|
2007-10-27 |
2009-04-30 |
Yongsheng Ma |
Promoter Detection and Analysis
|
|
US8067241B2
(en)
*
|
2009-08-26 |
2011-11-29 |
General Electric Company |
Method and apparatus for antigen retrieval process
|
|
ES2680915T3
(es)
*
|
2010-01-28 |
2018-09-11 |
The Children's Hospital Of Philadelphia |
Plataforma de fabricación escalable para la purificación de vectores virales y vectores virales purificados de este modo para su utilización en terapia génica
|
|
JP2013523175A
(ja)
|
2010-04-14 |
2013-06-17 |
イーエムディー・ミリポア・コーポレーション |
高力価、高純度のウイルスストックの作製方法及びその使用方法
|
|
WO2012018628A1
(en)
|
2010-07-26 |
2012-02-09 |
Board Of Regents, The University Of Texas System |
Methods for inducing an immune response via buccal and/or sublingual administration of a vaccine
|
|
WO2012122625A1
(en)
*
|
2011-03-14 |
2012-09-20 |
National Research Council Of Canada |
Method of viral production in cells
|
|
CA2856137A1
(en)
|
2011-11-22 |
2013-05-30 |
The Children's Hospital Of Philadelphia |
Virus vectors for highly efficient transgene delivery
|
|
WO2013090409A1
(en)
|
2011-12-12 |
2013-06-20 |
The Children's Hospital Of Philadelphia |
Large commercial scale lentiviral vector production system and vectors produced thereby
|
|
US9974850B2
(en)
|
2013-01-25 |
2018-05-22 |
Board Of Regents, The University Of Texas System |
Immunogenic compositions and uses thereof
|
|
PT3010537T
(pt)
*
|
2013-06-17 |
2019-12-03 |
De Staat Der Nederlanden Vert Door De Mini Van Vws Miniie Van Volksgezondheid Welzijn En Sport |
Métodos para a prevenção da agregação de componentes virais
|
|
CN105765066B
(zh)
*
|
2013-11-29 |
2018-12-14 |
宝生物工程株式会社 |
用于定量腺伴随病毒的方法
|
|
CA3205555A1
(en)
|
2014-04-25 |
2015-10-29 |
Genethon |
Treatment of hyperbilirubinemia
|
|
US10577627B2
(en)
|
2014-06-09 |
2020-03-03 |
Voyager Therapeutics, Inc. |
Chimeric capsids
|
|
WO2016004319A1
(en)
*
|
2014-07-02 |
2016-01-07 |
University Of Florida Research Foundation, Inc. |
Compositions and methods for purifying recombinant adeno-associated virus
|
|
CN107106689A
(zh)
|
2014-11-05 |
2017-08-29 |
沃雅戈治疗公司 |
用于治疗帕金森病的aadc多核苷酸
|
|
CN112410338A
(zh)
|
2014-11-14 |
2021-02-26 |
沃雅戈治疗公司 |
调节性多核苷酸
|
|
IL292999A
(en)
|
2014-11-14 |
2022-07-01 |
Voyager Therapeutics Inc |
Compositions and methods of treating amyotrophic lateral sclerosis (als)
|
|
WO2016094783A1
(en)
|
2014-12-12 |
2016-06-16 |
Voyager Therapeutics, Inc. |
Compositions and methods for the production of scaav
|
|
CN107428799A
(zh)
*
|
2015-01-13 |
2017-12-01 |
阿尔法韦士曼公司 |
纯化腺相关病毒(AAV)及/或重组腺相关病毒(rAAV)之方法及其梯度和流通式缓冲液
|
|
EP3054007A1
(en)
|
2015-02-09 |
2016-08-10 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Recombinant adeno-associated virus particle purification comprising an immuno-affinity purification step
|
|
EP3368054A4
(en)
|
2015-10-28 |
2019-07-03 |
Voyager Therapeutics, Inc. |
REGULATORY EXPRESSION USING THE ADENO-ASSOCIATED VIRUS (AAV)
|
|
EP3377042A4
(en)
|
2015-11-16 |
2019-05-29 |
The Research Institute at Nationwide Children's Hospital |
MATERIALS AND METHOD FOR THE TREATMENT OF TITIN-BASED MYOPATHIES AND OTHER TITINOPATHIES
|
|
WO2017100676A1
(en)
*
|
2015-12-11 |
2017-06-15 |
The Trustees Of The University Of Pennsylvania |
Scalable purification method for aav8
|
|
LT3436593T
(lt)
|
2016-03-28 |
2023-03-10 |
Ultragenyx Pharmaceutical Inc. |
Adenoviruso šiluminio inaktyvavimo būdai
|
|
WO2017189964A2
(en)
|
2016-04-29 |
2017-11-02 |
Voyager Therapeutics, Inc. |
Compositions for the treatment of disease
|
|
US11326182B2
(en)
|
2016-04-29 |
2022-05-10 |
Voyager Therapeutics, Inc. |
Compositions for the treatment of disease
|
|
KR20220108216A
(ko)
|
2016-05-18 |
2022-08-02 |
보이저 테라퓨틱스, 인크. |
헌팅톤 질환을 치료하기 위한 조성물 및 방법
|
|
SG11201809699XA
(en)
|
2016-05-18 |
2018-12-28 |
Voyager Therapeutics Inc |
Modulatory polynucleotides
|
|
KR20190045174A
(ko)
*
|
2016-07-21 |
2019-05-02 |
스파크 테라퓨틱스, 인코포레이티드 |
재조합 아데노신 관련 바이러스(rAAV) 벡터를 고수율로 생산하기 위한 확장 가능한 고회수 방법 및 이에 의해 생산된 재조합 아데노-관련 바이러스(rAAV) 벡터
|
|
EP3510161A4
(en)
|
2016-08-23 |
2020-04-22 |
Akouos, Inc. |
COMPOSITIONS AND METHODS FOR TREATING PERSONAL HEARING LOSS IN A PERSON
|
|
CN110650673B
(zh)
|
2016-08-30 |
2024-04-09 |
加利福尼亚大学董事会 |
用于生物医学靶向和递送的方法以及用于实践该方法的装置和系统
|
|
EP3293259A1
(en)
|
2016-09-12 |
2018-03-14 |
Genethon |
Acid-alpha glucosidase variants and uses thereof
|
|
PE20191203A1
(es)
|
2016-09-12 |
2019-09-10 |
Genethon |
Variantes de alfa-glucosidasa acida y usos de las mismas
|
|
EP3293260A1
(en)
|
2016-09-12 |
2018-03-14 |
Genethon |
Acid-alpha glucosidase variants and uses thereof
|
|
EP3293203A1
(en)
|
2016-09-12 |
2018-03-14 |
Genethon |
Acid-alpha glucosidase variants and uses thereof
|
|
US11166915B2
(en)
|
2016-09-16 |
2021-11-09 |
Leukocare Ag |
Method for obtaining efficient viral vector-based compositions for vaccination or gene therapy
|
|
PT3534922T
(pt)
|
2016-11-04 |
2024-06-07 |
Takeda Pharmaceuticals Co |
Formulações de vírus adenoassociado
|
|
US10626376B2
(en)
|
2016-11-14 |
2020-04-21 |
St. Jude Children's Research Hospital |
Method for isolating and purifying adeno-associated virus particles using salt
|
|
US10294452B2
(en)
*
|
2016-11-22 |
2019-05-21 |
Dao-Yao He |
Lysis, extraction and purification of adeno-associated virus and adenovirus from host cells
|
|
EP3576796A1
(en)
|
2017-02-01 |
2019-12-11 |
Centre National De La Recherche Scientifique |
Particles and compositions comprising the same for transfection
|
|
WO2018162748A1
(en)
|
2017-03-10 |
2018-09-13 |
Genethon |
Treatment of glycogen storage disease iii
|
|
JP2020518259A
(ja)
|
2017-05-05 |
2020-06-25 |
ボイジャー セラピューティクス インコーポレイテッドＶｏｙａｇｅｒ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． |
ハンチントン病治療組成物および方法
|
|
SG11201909870SA
(en)
|
2017-05-05 |
2019-11-28 |
Voyager Therapeutics Inc |
Compositions and methods of treating amyotrophic lateral sclerosis (als)
|
|
JOP20190269A1
(ar)
|
2017-06-15 |
2019-11-20 |
Voyager Therapeutics Inc |
بولي نوكليوتيدات aadc لعلاج مرض باركنسون
|
|
JP7229989B2
(ja)
|
2017-07-17 |
2023-02-28 |
ボイジャー セラピューティクス インコーポレイテッド |
軌道アレイガイドシステム
|
|
TWI832036B
(zh)
|
2017-08-03 |
2024-02-11 |
美商航海家醫療公司 |
用於aav之遞送之組合物及方法
|
|
MX2020003042A
(es)
|
2017-09-29 |
2020-11-18 |
Voyager Therapeutics Inc |
Rescate del fenotipo neurológico central y periférico de la ataxia de friedreich mediante administración intravenosa.
|
|
EP4454654A3
(en)
|
2017-10-16 |
2025-02-19 |
Voyager Therapeutics, Inc. |
Treatment of amyotrophic lateral sclerosis (als)
|
|
US11434502B2
(en)
|
2017-10-16 |
2022-09-06 |
Voyager Therapeutics, Inc. |
Treatment of amyotrophic lateral sclerosis (ALS)
|
|
CN120505370A
(zh)
*
|
2017-11-08 |
2025-08-19 |
诺华股份有限公司 |
制备病毒载体的手段和方法及其用途
|
|
AU2018378590A1
(en)
*
|
2017-12-05 |
2020-06-25 |
Beacon Therapeutics Limited |
Formulation optimization for viral particles
|
|
AR114350A1
(es)
|
2018-01-31 |
2020-08-26 |
Res Institute At Nationwide ChildrenS Hospital |
Terapia genética para la distrofia muscular de cinturas del tipo 2c
|
|
CN120665951A
(zh)
|
2018-02-07 |
2025-09-19 |
吉尼松公司 |
杂合调控元件
|
|
US20210010028A1
(en)
|
2018-03-06 |
2021-01-14 |
Voyager Therapeutics, Inc. |
Insect cell manufactured partial self-complementary aav genomes
|
|
US12129476B2
(en)
|
2018-04-27 |
2024-10-29 |
Voyager Therapeutics, Inc. |
Methods for measuring the potency of AADC viral vectors
|
|
EP3794126A1
(en)
|
2018-05-15 |
2021-03-24 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of parkinson's disease
|
|
EP3793686A1
(en)
|
2018-05-16 |
2021-03-24 |
Voyager Therapeutics, Inc. |
Aav serotypes for brain specific payload delivery
|
|
EP3793615A2
(en)
|
2018-05-16 |
2021-03-24 |
Voyager Therapeutics, Inc. |
Directed evolution of aav to improve tropism for cns
|
|
US12228571B2
(en)
|
2018-06-08 |
2025-02-18 |
Novartis Ag |
Cell-based assay for measuring drug product potency
|
|
CN113528510A
(zh)
|
2018-06-29 |
2021-10-22 |
武汉纽福斯生物科技有限公司 |
治疗遗传性视神经病变的组合物和方法
|
|
WO2020006458A1
(en)
|
2018-06-29 |
2020-01-02 |
Research Institute At Nationwide Children's Hospital |
Recombinant adeno-associated virus products and methods for treating limb girdle muscular dystrophy 2a
|
|
CA3103963A1
(en)
|
2018-07-02 |
2020-01-09 |
Voyager Therapeutics, Inc. |
Treatment of amyotrophic lateral sclerosis and disorders associated with the spinal cord
|
|
AU2019299964A1
(en)
*
|
2018-07-11 |
2021-01-21 |
Takeda Pharmaceutical Company Limited |
AAV compositions
|
|
JP2021530548A
(ja)
|
2018-07-24 |
2021-11-11 |
ボイジャー セラピューティクス インコーポレイテッドVoyager Therapeutics, Inc. |
遺伝子治療製剤を生産するための系および方法
|
|
CA3107572A1
(en)
|
2018-08-08 |
2020-02-13 |
Genethon |
Mini-gde for the treatment of glycogen storage disease iii
|
|
US12612644B2
(en)
*
|
2018-08-10 |
2026-04-28 |
Regenxbio Inc. |
Scalable method for recombinant AAV production
|
|
CA3109432A1
(en)
|
2018-08-20 |
2020-02-27 |
Wuhan Neurophth Biotechnology Limited Company |
Compositions and methods for treating leber's hereditary optic neuropathy
|
|
CN113383010B
(zh)
|
2018-09-28 |
2025-09-09 |
沃雅戈治疗公司 |
具有经工程化改造的启动子的共济蛋白表达构建体及其使用方法
|
|
TW202035689A
(zh)
|
2018-10-04 |
2020-10-01 |
美商航海家醫療公司 |
測量病毒載體粒子的效價及強度之方法
|
|
MX2021008542A
(es)
|
2019-01-18 |
2021-11-12 |
Voyager Therapeutics Inc |
Métodos y sistemas para la producción de partículas de aav.
|
|
CA3131390A1
(en)
|
2019-02-26 |
2020-09-03 |
Research Institute Of Nationwide Children's Hospital |
Adeno-associated virus vector delivery of b-sarcoglycan and the treatment of muscular dystrophy
|
|
US20220162640A1
(en)
|
2019-04-08 |
2022-05-26 |
Genethon |
Hybrid promoters for muscle expression
|
|
KR20210153069A
(ko)
|
2019-04-19 |
2021-12-16 |
제네똥 |
섬유아세포 성장 인자 23 관련 저인산혈증성 질환의 유전자 요법
|
|
WO2020214929A1
(en)
*
|
2019-04-19 |
2020-10-22 |
Regenxbio Inc. |
Adeno-associated virus vector formulations and methods
|
|
WO2020223274A1
(en)
|
2019-04-29 |
2020-11-05 |
Voyager Therapeutics, Inc. |
SYSTEMS AND METHODS FOR PRODUCING BACULOVIRAL INFECTED INSECT CELLS (BIICs) IN BIOREACTORS
|
|
AU2020319168B2
(en)
|
2019-07-25 |
2024-02-29 |
Novartis Ag |
Regulatable expression systems
|
|
US20220290182A1
(en)
|
2019-08-09 |
2022-09-15 |
Voyager Therapeutics, Inc. |
Cell culture medium for use in producing gene therapy products in bioreactors
|
|
US20220325250A1
(en)
|
2019-08-14 |
2022-10-13 |
Leukocare Ag |
Method for obtaining efficient compositions comprising viral vectors for vaccination or gene therapy
|
|
US11401530B2
(en)
|
2019-08-19 |
2022-08-02 |
The Catholic University Of America |
Bacteriophage-based artificial viruses for human genome remodeling
|
|
US11155835B2
(en)
*
|
2019-08-19 |
2021-10-26 |
The Catholic University Of America |
Prokaryotic-eukaryotic hybrid viral vector for delivery of large cargos of genes and proteins into human cells
|
|
EP4488287A3
(en)
|
2019-08-21 |
2025-03-05 |
Research Institute at Nationwide Children's Hospital |
Adeno-associated virus vector delivery of alpha-sarcoglycan and the treatment of muscular dystrophy
|
|
WO2021041485A1
(en)
|
2019-08-26 |
2021-03-04 |
Voyager Therapeutics, Inc. |
Controlled expression of viral proteins
|
|
CN114728049A
(zh)
|
2019-10-07 |
2022-07-08 |
再生生物股份有限公司 |
腺相关病毒载体药物组合物和方法
|
|
CN114555808A
(zh)
|
2019-10-22 |
2022-05-27 |
吉尼松公司 |
嵌合多肽及其用途
|
|
WO2021078834A1
(en)
|
2019-10-22 |
2021-04-29 |
Genethon |
Chimeric acid-alpha glucosidase polypeptides and uses thereof
|
|
CN113025633B
(zh)
|
2019-12-09 |
2024-08-27 |
武汉纽福斯生物科技有限公司 |
编码人nadh脱氢酶亚单位1蛋白的核酸及其应用
|
|
KR102167829B1
(ko)
*
|
2020-02-10 |
2020-10-20 |
주식회사 이노테라피 |
아데노연관바이러스용 안정화제 및 이를 이용한 아데노연관바이러스의 안정화 방법
|
|
CN116096905A
(zh)
|
2020-02-21 |
2023-05-09 |
阿库斯股份有限公司 |
用于治疗人受试者的非年龄相关性听力损伤的组合物和方法
|
|
WO2021236908A2
(en)
|
2020-05-20 |
2021-11-25 |
Biomarin Pharmaceutical Inc. |
Use of regulatory proteins for the production of adeno-associated virus
|
|
EP3913060A1
(en)
|
2020-05-22 |
2021-11-24 |
Genethon |
Vectors encoding a glucose-6-phosphatase (g6pase-a) for gene therapy
|
|
CN116096867A
(zh)
*
|
2020-06-02 |
2023-05-09 |
詹森生物科技公司 |
用于病毒纯化的材料和方法
|
|
WO2022032153A1
(en)
|
2020-08-06 |
2022-02-10 |
Voyager Therapeutics, Inc. |
Cell culture medium for use in producing gene therapy products in bioreactors
|
|
US20220040305A1
(en)
*
|
2020-08-07 |
2022-02-10 |
Janssen Biotech, Inc. |
Formulations for highly purified viral particles
|
|
EP4200410A1
(en)
|
2020-08-24 |
2023-06-28 |
Genethon |
C-terminal truncated gde for the treatment of glycogen storage disease iii
|
|
US20230407328A1
(en)
|
2020-11-02 |
2023-12-21 |
Biomarin Pharmaceutical Inc. |
Process for enriching adeno-associated virus
|
|
EP4259790A1
(en)
|
2020-12-09 |
2023-10-18 |
Genethon |
Lysosomal acid lipase variants and uses thereof
|
|
EP4301768A2
(en)
|
2021-03-03 |
2024-01-10 |
Voyager Therapeutics, Inc. |
Controlled expression of viral proteins
|
|
US20240141378A1
(en)
|
2021-03-03 |
2024-05-02 |
Voyager Therapeutics, Inc. |
Controlled expression of viral proteins
|
|
WO2022208342A1
(en)
*
|
2021-04-01 |
2022-10-06 |
Pfizer Inc. |
Pharmaceutical compositions containing adeno-associated viral vector
|
|
EP4333896A4
(en)
*
|
2021-05-07 |
2025-03-19 |
Board of Regents, The University of Texas System |
Methods and compositions for transport, storage, and delivery of adeno-associated viral vectors and other molecules
|
|
CN117897492A
(zh)
|
2021-08-04 |
2024-04-16 |
吉尼松公司 |
用于肌肉和cns中的基因表达的杂合启动子
|
|
US20240398985A1
(en)
|
2021-09-16 |
2024-12-05 |
Novartis Ag |
Novel transcription factors
|
|
US12285497B2
(en)
|
2021-10-15 |
2025-04-29 |
Research Institute At Nationwide Children's Hospital |
Self-complementary adeno-associated virus vector and its use in treatment of muscular dystrophy
|
|
US20250235554A1
(en)
|
2021-10-25 |
2025-07-24 |
Novartis Ag |
Methods for improving adeno-associated virus (aav) delivery
|
|
EP4511392A1
(en)
|
2022-03-17 |
2025-02-26 |
Innoskel |
Polynucleotides encoding the alpha-1 chain of human type ii collagen and methods of their use
|
|
WO2023175585A1
(en)
|
2022-03-17 |
2023-09-21 |
Innoskel |
Hybrid promoters and their use in osteolysis syndrome
|
|
JP2025517628A
(ja)
|
2022-05-06 |
2025-06-10 |
ノバルティス アーゲー |
新規の組換えａａｖ ｖｐ２融合ポリペプチド
|
|
CA3252764A1
(en)
|
2022-06-09 |
2023-12-14 |
Institut National de la Santé et de la Recherche Médicale |
GDE truncated at the N-terminal level for the treatment of type III glycogen storage disease
|
|
US20260085328A1
(en)
|
2022-09-08 |
2026-03-26 |
Voyager Therapeutics, Inc. |
Controlled expression of viral proteins
|
|
TW202426017A
(zh)
*
|
2022-11-24 |
2024-07-01 |
俄羅斯聯邦商拜奧卡德聯合股份公司 |
非包膜病毒的藥物組合物
|
|
CN121420060A
(zh)
|
2023-06-29 |
2026-01-27 |
吉尼松公司 |
用于治疗糖原贮积病iii的n-端截短的糖原脱支酶
|
|
EP4606892A1
(en)
|
2024-02-23 |
2025-08-27 |
Merck Patent GmbH |
Methods for the production of viral particles
|