ES2647477T3 - Composiciones y métodos para prevenir la agregación del vector AAV - Google Patents

Composiciones y métodos para prevenir la agregación del vector AAV Download PDF

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Publication number
ES2647477T3
ES2647477T3 ES05755269.7T ES05755269T ES2647477T3 ES 2647477 T3 ES2647477 T3 ES 2647477T3 ES 05755269 T ES05755269 T ES 05755269T ES 2647477 T3 ES2647477 T3 ES 2647477T3
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Prior art keywords
vector
aggregation
aav2
virions
excipients
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Expired - Lifetime
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ES05755269.7T
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English (en)
Spanish (es)
Inventor
John Fraser Wright
Guang Qu
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Genzyme Corp
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Genzyme Corp
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14151—Methods of production or purification of viral material

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Curing Cements, Concrete, And Artificial Stone (AREA)
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ES05755269.7T 2004-06-01 2005-06-01 Composiciones y métodos para prevenir la agregación del vector AAV Expired - Lifetime ES2647477T3 (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US57599704P 2004-06-01 2004-06-01
US575997P 2004-06-01
US63922204P 2004-12-22 2004-12-22
US639222P 2004-12-22
PCT/US2005/019235 WO2005118792A1 (en) 2004-06-01 2005-06-01 Compositions and methods to prevent aav vector aggregation

Publications (1)

Publication Number Publication Date
ES2647477T3 true ES2647477T3 (es) 2017-12-21

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ES05755269.7T Expired - Lifetime ES2647477T3 (es) 2004-06-01 2005-06-01 Composiciones y métodos para prevenir la agregación del vector AAV
ES17186206T Expired - Lifetime ES2932278T3 (es) 2004-06-01 2005-06-01 Composiciones y métodos para prevenir la agregación del vector AAV

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ES17186206T Expired - Lifetime ES2932278T3 (es) 2004-06-01 2005-06-01 Composiciones y métodos para prevenir la agregación del vector AAV

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US (4) US7704721B2 (enExample)
EP (3) EP1751275B1 (enExample)
JP (5) JP2008501339A (enExample)
BR (1) BRPI0511764B8 (enExample)
CA (1) CA2569244C (enExample)
DK (2) DK1751275T3 (enExample)
ES (2) ES2647477T3 (enExample)
HU (2) HUE060433T2 (enExample)
MX (3) MXPA06014030A (enExample)
WO (1) WO2005118792A1 (enExample)

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Publication number Publication date
MXPA06014030A (es) 2007-10-08
BRPI0511764B1 (pt) 2017-10-24
MX2019006353A (es) 2022-06-27
US7704721B2 (en) 2010-04-27
ES2932278T3 (es) 2023-01-17
WO2005118792A1 (en) 2005-12-15
EP3290513B1 (en) 2022-09-07
US20060035364A1 (en) 2006-02-16
EP4170024A1 (en) 2023-04-26
DK3290513T3 (da) 2022-12-12
JP2019058177A (ja) 2019-04-18
HUE060433T2 (hu) 2023-03-28
CA2569244C (en) 2017-02-14
MX360727B (es) 2018-11-14
BRPI0511764B8 (pt) 2021-05-25
JP2014111625A (ja) 2014-06-19
JP2012143233A (ja) 2012-08-02
US20160083694A1 (en) 2016-03-24
CA2569244A1 (en) 2005-12-15
JP2016195587A (ja) 2016-11-24
EP3290513A1 (en) 2018-03-07
US9051542B2 (en) 2015-06-09
EP1751275B1 (en) 2017-08-16
DK1751275T3 (da) 2017-11-27
US20170247664A1 (en) 2017-08-31
HUE035418T2 (en) 2018-05-02
JP5769650B2 (ja) 2015-08-26
BRPI0511764A (pt) 2008-01-08
EP1751275A4 (en) 2008-01-23
JP2008501339A (ja) 2008-01-24
EP1751275A1 (en) 2007-02-14
US20110076744A1 (en) 2011-03-31

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