JP2015504870A - 線維症を処置するためのアンジオテンシン - Google Patents

線維症を処置するためのアンジオテンシン Download PDF

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Publication number
JP2015504870A
JP2015504870A JP2014547526A JP2014547526A JP2015504870A JP 2015504870 A JP2015504870 A JP 2015504870A JP 2014547526 A JP2014547526 A JP 2014547526A JP 2014547526 A JP2014547526 A JP 2014547526A JP 2015504870 A JP2015504870 A JP 2015504870A
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angiotensin
analog
derivative
fibrosis
peptide
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JP2014547526A
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Japanese (ja)
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JP2015504870A5 (enExample
Inventor
リチャード フランクリン,
リチャード フランクリン,
ポール ベリンガー,
ポール ベリンガー,
Original Assignee
タリックス ファーマシューティカルズ リミテッド
タリックス ファーマシューティカルズ リミテッド
ユニバーシティ オブ サザン カリフォルニア
ユニバーシティ オブ サザン カリフォルニア
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Publication of JP2015504870A publication Critical patent/JP2015504870A/ja
Publication of JP2015504870A5 publication Critical patent/JP2015504870A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/085—Angiotensins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Reinforced Plastic Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2014547526A 2011-12-16 2012-12-14 線維症を処置するためのアンジオテンシン Pending JP2015504870A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161576673P 2011-12-16 2011-12-16
US61/576,673 2011-12-16
US201161579936P 2011-12-23 2011-12-23
US61/579,936 2011-12-23
PCT/US2012/069930 WO2013090833A1 (en) 2011-12-16 2012-12-14 Angiotensins for treatment of fibrosis

Publications (2)

Publication Number Publication Date
JP2015504870A true JP2015504870A (ja) 2015-02-16
JP2015504870A5 JP2015504870A5 (enExample) 2016-02-12

Family

ID=48613248

Family Applications (1)

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JP2014547526A Pending JP2015504870A (ja) 2011-12-16 2012-12-14 線維症を処置するためのアンジオテンシン

Country Status (9)

Country Link
US (2) US20150057216A1 (enExample)
EP (1) EP2790716A4 (enExample)
JP (1) JP2015504870A (enExample)
KR (1) KR20150028761A (enExample)
CN (1) CN104302305A (enExample)
AU (1) AU2012351939A1 (enExample)
BR (1) BR112014014674A2 (enExample)
CA (1) CA2859573A1 (enExample)
WO (1) WO2013090833A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022549086A (ja) * 2019-09-20 2022-11-24 ヴィコール ファルマ アーベー 新化合物
JP2023515084A (ja) * 2020-02-20 2023-04-12 リー・シュー-ロン アンジオテンシン調節酵素のモジュレーターとしてのジンセノサイドm1、およびコロナウイルスによって引き起こされる症状を含む疾患または病気の治療のためのその使用

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LT1993360T (lt) 2005-12-28 2017-06-12 Vertex Pharmaceuticals Incorporated N-[2,4-bis(1,1-dimetiletil)-5-hidroksifenil]-1,4-dihidro-4-oksochinolin-3-karboksamido kieta forma
JP2016520592A (ja) * 2013-05-24 2016-07-14 タリックス ファーマシューティカルズ リミテッド マルファン症候群および関連障害の処置におけるアンジオテンシンペプチド
AU2014284496A1 (en) * 2013-07-03 2016-01-21 The Arizona Board Of Regents On Behalf Of The University Of Arizona Method for treating cognitive dysfunction
US20170080120A1 (en) * 2014-05-16 2017-03-23 Ulstrast, Inc. Phase-shifting formulations
US10183055B2 (en) 2014-07-21 2019-01-22 Arizona Board Of Regents On Behalf Of The University Of Arizona Ang-(1-7) derivative oligopeptides for the treatment of pain and other indications
CN106535920B (zh) 2014-07-21 2020-10-30 代表亚利桑那大学的亚利桑那校董会 Ang-(1-7)衍生物寡肽及其使用和生产方法
CA2963945C (en) 2014-10-07 2023-01-10 Vertex Pharmaceuticals Incorporated Co-crystals of modulators of cystic fibrosis transmembrane conductance regulator
MA41120A (fr) * 2014-12-02 2017-10-10 Afimmune Ltd Compositions comprenant le 15-hepe et méthodes de traitement ou de prévention de la fibrose à l'aide de celles-ci
WO2017015720A1 (en) 2015-07-30 2017-02-02 Monash University Fibrotic treatment
US10960045B2 (en) * 2015-10-14 2021-03-30 Constant Therapeutics Llc Methods and compositions for the treatment of epidermolysis bullosa
WO2017218623A1 (en) * 2016-06-14 2017-12-21 Tarix Orphan Llc Methods and compositions for the treatment of epidermolysis bullosa
CN111163793A (zh) * 2017-07-17 2020-05-15 莫纳什大学 血管紧张素受体激动剂及其用途
US20210315851A1 (en) 2020-04-03 2021-10-14 Afimmune Limited Compositions comprising 15-hepe and methods of treating or preventing hematologic disorders, and/or related diseases
EP4085896A1 (en) * 2021-05-04 2022-11-09 CU-Pharmaceuticals UG Pharmaceutical angiotensin-(1-7) compositions in the treatment of (sars)-cov- or (sars)-cov-2-infection related diseases
EP4085921A1 (en) * 2021-05-04 2022-11-09 CU-Pharmaceuticals UG Angiotensin-(1-7) in the treatment of sars-cov related diseases
KR20240148359A (ko) 2022-02-10 2024-10-11 바이코어 파마 아베 특발성 폐섬유증 치료를 위한 불록시부티드의 용도
GB202201723D0 (en) 2022-02-10 2022-03-30 Vicore Pharma Ab New use
EP4775589A1 (en) * 2023-09-08 2026-07-15 Pontificia Universidad Católica de Chile Pharmaceutical composition comprising a peptide or a combination of peptides agonistic to the mas, at1 and at2 receptors
KR102743940B1 (ko) 2023-10-06 2024-12-19 엠브릭스 주식회사 안지오텐신 전환효소 2 및 Fc 절편을 포함하는 나노디스크 및 이의 용도

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ATE268782T1 (de) * 1997-12-12 2004-06-15 Univ Southern California Zusammensetzungen zur wundheilung
YU78601A (sh) * 1999-05-05 2005-07-19 Aventis Pharma Deutschland Gmbh. 1-(p-tienilbenzil)-imidazoli kao agonisti angiotenzin-(1-7)- receptora, postupak za njihovu proizvodnju, njihova primena i farmaceutski preparati koji ih sadrže
US7064127B2 (en) * 2003-12-19 2006-06-20 Mount Sinai School Of Medicine Of New York University Treatment of hepatic fibrosis with imatinib mesylate
ES2393455T3 (es) * 2008-09-12 2012-12-21 Charité-Universitátsmedizin Berlin (Charité) Uso de un agonista del receptor Ang-(1-7) en lesiones pulmonares agudas

Non-Patent Citations (4)

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Title
JPN6016018990; Clinical Science Vol.117,No.11, 2009, p375-386 *
JPN6016018991; Regulatory Peptides Vol.162,No.1-3, 2010, p73-78 *
JPN6016018992; Cancer Research Vol.70,No.21, 2010, p8319-8328 *
JPN6016018993; Journal of Hepatology Vol.46,No.4, 2006, p674-681 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022549086A (ja) * 2019-09-20 2022-11-24 ヴィコール ファルマ アーベー 新化合物
JP7771049B2 (ja) 2019-09-20 2025-11-17 ヴィコール ファルマ アーベー 新化合物
JP2023515084A (ja) * 2020-02-20 2023-04-12 リー・シュー-ロン アンジオテンシン調節酵素のモジュレーターとしてのジンセノサイドm1、およびコロナウイルスによって引き起こされる症状を含む疾患または病気の治療のためのその使用
JP7814312B2 (ja) 2020-02-20 2026-02-16 リー・シュー-ロン アンジオテンシン調節酵素のモジュレーターとしてのジンセノサイドm1、およびコロナウイルスによって引き起こされる症状を含む疾患または病気の治療のためのその使用

Also Published As

Publication number Publication date
WO2013090833A1 (en) 2013-06-20
US20150057216A1 (en) 2015-02-26
WO2013090833A8 (en) 2014-07-17
AU2012351939A1 (en) 2014-07-10
US20160074466A1 (en) 2016-03-17
KR20150028761A (ko) 2015-03-16
BR112014014674A2 (pt) 2017-06-13
CN104302305A (zh) 2015-01-21
CA2859573A1 (en) 2013-06-20
EP2790716A4 (en) 2015-06-10
EP2790716A1 (en) 2014-10-22

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