JP2014511366A5 - - Google Patents

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Publication number
JP2014511366A5
JP2014511366A5 JP2013551335A JP2013551335A JP2014511366A5 JP 2014511366 A5 JP2014511366 A5 JP 2014511366A5 JP 2013551335 A JP2013551335 A JP 2013551335A JP 2013551335 A JP2013551335 A JP 2013551335A JP 2014511366 A5 JP2014511366 A5 JP 2014511366A5
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JP
Japan
Prior art keywords
substituted
unsubstituted
pharmaceutical composition
independently selected
composition according
Prior art date
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Application number
JP2013551335A
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English (en)
Japanese (ja)
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JP2014511366A (ja
JP6010548B2 (ja
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Priority claimed from PCT/US2012/022724 external-priority patent/WO2012103336A1/en
Publication of JP2014511366A publication Critical patent/JP2014511366A/ja
Publication of JP2014511366A5 publication Critical patent/JP2014511366A5/ja
Application granted granted Critical
Publication of JP6010548B2 publication Critical patent/JP6010548B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2013551335A 2011-01-26 2012-01-26 小分子RNase阻害剤および使用方法 Expired - Fee Related JP6010548B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161436342P 2011-01-26 2011-01-26
US61/436,342 2011-01-26
PCT/US2012/022724 WO2012103336A1 (en) 2011-01-26 2012-01-26 Small molecule rnase inhibitors and methods of use

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016150928A Division JP6248151B2 (ja) 2011-01-26 2016-08-01 小分子RNase阻害剤および使用方法

Publications (3)

Publication Number Publication Date
JP2014511366A JP2014511366A (ja) 2014-05-15
JP2014511366A5 true JP2014511366A5 (enExample) 2015-03-05
JP6010548B2 JP6010548B2 (ja) 2016-10-19

Family

ID=46581163

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2013551321A Pending JP2014510717A (ja) 2011-01-26 2012-01-26 小分子RNase阻害剤および使用方法
JP2013551335A Expired - Fee Related JP6010548B2 (ja) 2011-01-26 2012-01-26 小分子RNase阻害剤および使用方法
JP2016150928A Expired - Fee Related JP6248151B2 (ja) 2011-01-26 2016-08-01 小分子RNase阻害剤および使用方法

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2013551321A Pending JP2014510717A (ja) 2011-01-26 2012-01-26 小分子RNase阻害剤および使用方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2016150928A Expired - Fee Related JP6248151B2 (ja) 2011-01-26 2016-08-01 小分子RNase阻害剤および使用方法

Country Status (7)

Country Link
US (4) US9089545B2 (enExample)
EP (3) EP2667872B1 (enExample)
JP (3) JP2014510717A (enExample)
CN (2) CN103635193B (enExample)
AU (2) AU2012211253B2 (enExample)
CA (2) CA2825907C (enExample)
WO (2) WO2012103336A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2012211253B2 (en) 2011-01-26 2016-11-10 Board Of Regents Of The University Of Nebraska Small molecule RNase inhibitors and methods of use
SG11201700777VA (en) 2014-08-04 2017-02-27 Nuevolution As Optionally fused heterocyclyl-substituted derivatives of pyrimidine useful for the treatment of inflammatory, metabolic, oncologic and autoimmune diseases
AU2015339039B2 (en) * 2014-10-31 2019-11-28 Temple University -- Of The Commonwealth System Of Higher Education Synergistic compositions for treating microbial infections
US10351890B2 (en) 2014-12-09 2019-07-16 Medicosbiotech, Inc. Method for preparing recombinant proteins through reduction of rnpA gene expression
WO2016093606A1 (ko) * 2014-12-09 2016-06-16 한국과학기술원 rnpA 유전자 발현감소를 통한 재조합단백질의 제조방법
EP3697777A1 (en) 2017-10-19 2020-08-26 eFFECTOR Therapeutics, Inc. Benzimidazole-indole inhibitors of mnk1 and mnk2
US11447479B2 (en) 2019-12-20 2022-09-20 Nuevolution A/S Compounds active towards nuclear receptors
TWI872177B (zh) 2019-12-20 2025-02-11 丹麥商紐韋盧森公司 對核受體具有活性之化合物
JP7713953B2 (ja) 2020-03-31 2025-07-28 ヌエヴォリューション・アクティーゼルスカブ 核内受容体に対して活性な化合物
CA3174176A1 (en) 2020-03-31 2021-10-07 Sanne Schroder Glad Compounds active towards nuclear receptors

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD264918A1 (de) * 1987-11-26 1989-02-15 Paedagogische Hochschule Lisel Verfahren zur herstellung von 1,4-diacyl-thiosemicarbaziden
JPH03182742A (ja) * 1989-12-12 1991-08-08 Fuji Photo Film Co Ltd ハロゲン化銀写真感光材料
US6936432B2 (en) 2000-03-01 2005-08-30 Message Pharmaceuticals Bacterial RNase P proteins and their use in identifying antibacterial compounds
US20020123077A1 (en) 2000-09-29 2002-09-05 O'toole George A. Novel compounds capable of modulating biofilms
US20020052396A1 (en) * 2001-04-23 2002-05-02 Bailey Thomas R. Compounds, compositions and methods for treating or preventing viral infections and associated diseases
US7001924B2 (en) * 2001-09-21 2006-02-21 Message Pharmaceuticals Inhibitors of RNase P proteins as antibacterial compounds
US20050042674A9 (en) 2002-02-21 2005-02-24 Lin Yu Common ligand mimics: thiazolidinediones and rhodanines
WO2003073999A2 (en) * 2002-03-01 2003-09-12 Pintex Pharmaceuticals, Inc. Pini-modulating compounds and methods of use thereof
GB2386892A (en) * 2002-03-28 2003-10-01 Pantherix Ltd Carboxy containing (phenyl-/heterocyclyl-)methylene substituted azole & azine derivatives and their therapeutic use as antibacterials
US20040176277A1 (en) * 2003-03-03 2004-09-09 Pintex Pharmaceuticals, Inc. Methods of treating Pin1 associated disorders
FR2858324A1 (fr) * 2003-07-30 2005-02-04 Centre Nat Rech Scient Nouveaux composes antibiotiques, compositions pharmaceutiques les contenant et leurs utilisations
WO2005039494A2 (en) * 2003-10-21 2005-05-06 Message Pharmaceuticals, Inc. Inhibitors of rnase p proteins as antibacterial compounds
US7718680B2 (en) * 2004-09-23 2010-05-18 Burnham Institute For Medical Research Inhibition of lethal factor protease activity from anthrax toxin
JP4122049B2 (ja) 2005-09-22 2008-07-23 明治製菓株式会社 メタロ−β−ラクタマーゼ阻害剤
AU2008345225A1 (en) * 2007-12-21 2009-07-09 University Of Rochester Method for altering the lifespan of eukaryotic organisms
CA2727651C (en) * 2008-06-17 2016-04-05 Priscille Brodin Anti-infective compounds
AU2012211253B2 (en) 2011-01-26 2016-11-10 Board Of Regents Of The University Of Nebraska Small molecule RNase inhibitors and methods of use

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