JP2014509860A5 - - Google Patents
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- Publication number
- JP2014509860A5 JP2014509860A5 JP2013558453A JP2013558453A JP2014509860A5 JP 2014509860 A5 JP2014509860 A5 JP 2014509860A5 JP 2013558453 A JP2013558453 A JP 2013558453A JP 2013558453 A JP2013558453 A JP 2013558453A JP 2014509860 A5 JP2014509860 A5 JP 2014509860A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- antibody according
- seq
- amino acid
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161453449P | 2011-03-16 | 2011-03-16 | |
| US61/453,449 | 2011-03-16 | ||
| PCT/EP2012/054629 WO2012123562A1 (en) | 2011-03-16 | 2012-03-16 | Diagnostic antibody assay |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014509860A JP2014509860A (ja) | 2014-04-24 |
| JP2014509860A5 true JP2014509860A5 (enExample) | 2015-04-23 |
| JP6220675B2 JP6220675B2 (ja) | 2017-11-01 |
Family
ID=45833428
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013558453A Expired - Fee Related JP6220675B2 (ja) | 2011-03-16 | 2012-03-16 | 診断用抗体アッセイ |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US8809508B2 (enExample) |
| EP (1) | EP2686346B1 (enExample) |
| JP (1) | JP6220675B2 (enExample) |
| KR (1) | KR102020072B1 (enExample) |
| CN (1) | CN103459421B (enExample) |
| AU (1) | AU2012228236B2 (enExample) |
| BR (1) | BR112013023211B1 (enExample) |
| CA (1) | CA2828433C (enExample) |
| DK (1) | DK2686346T3 (enExample) |
| EA (1) | EA032054B1 (enExample) |
| IL (1) | IL227847A0 (enExample) |
| MX (1) | MX343873B (enExample) |
| SG (1) | SG192805A1 (enExample) |
| WO (1) | WO2012123562A1 (enExample) |
| ZA (1) | ZA201305946B (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ712352A (en) | 2013-03-15 | 2016-07-29 | Probiodrug Ag | Novel inhibitors of glutaminyl cyclase |
| EP3234611A1 (en) | 2014-12-19 | 2017-10-25 | Probiodrug AG | Novel method for the detection of pglu-abeta peptides |
| US10494425B2 (en) * | 2015-02-24 | 2019-12-03 | Rpeptide, Llc | Anti-amyloid-beta antibodies |
| CN108699139B (zh) * | 2015-07-16 | 2022-06-24 | 维沃永治疗公众有限公司 | 人源化抗体 |
| GB201910697D0 (en) * | 2019-07-26 | 2019-09-11 | Binding Site Group Ltd | Lonisation control |
| CN114585883A (zh) * | 2019-10-01 | 2022-06-03 | 瑞普利金公司 | 流体中蛋白质浓度的测定 |
| KR102790945B1 (ko) * | 2022-09-23 | 2025-04-04 | 경성대학교 산학협력단 | 베타-아밀로이드 42를 이용한 치매 진단 방법 및 이를 이용한 치매 진단 키트 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4737456A (en) | 1985-05-09 | 1988-04-12 | Syntex (U.S.A.) Inc. | Reducing interference in ligand-receptor binding assays |
| DE60031792T2 (de) * | 1999-12-08 | 2007-02-22 | Intellect Neurosciences, Inc. | Schimärische amyloid-beta peptide |
| US7117096B2 (en) * | 2001-04-17 | 2006-10-03 | Abmaxis, Inc. | Structure-based selection and affinity maturation of antibody library |
| CA2487528A1 (en) | 2002-07-24 | 2004-02-12 | Innogenetics N.V. | Prevention, treatment and diagnosis of diseases associated with beta-amyloid formation and/or aggregation |
| WO2004029629A1 (en) * | 2002-09-27 | 2004-04-08 | Janssen Pharmaceutica N.V. | N-11 truncated amyloid-beta nomoclonal antibodies, compositions, methods and uses |
| JP4996926B2 (ja) | 2004-02-05 | 2012-08-08 | プロビオドルグ エージー | グルタミニルシクラーゼの新規の阻害剤 |
| ES2259270B1 (es) | 2005-03-09 | 2007-11-01 | Consejo Superior De Investigaciones Cientificas | Metodo de diagnostico in vitro de la enfermedad de alzheimer mediante un anticuerpo monoclonal. |
| US20100028351A1 (en) | 2006-06-29 | 2010-02-04 | Marc Mercken | Anti-amyloid antibodies, compositions, methods and uses |
| EP2091945B1 (en) | 2006-11-09 | 2014-01-15 | Probiodrug AG | Novel inhibitors of glutaminyl cyclase |
| JP5379692B2 (ja) | 2006-11-09 | 2013-12-25 | プロビオドルグ エージー | 潰瘍、癌及び他の疾患の治療のためのグルタミニルシクラーゼの阻害薬としての３−ヒドロキシ−１，５−ジヒドロ−ピロール−２−オン誘導体 |
| WO2008055950A1 (en) | 2006-11-09 | 2008-05-15 | Probiodrug Ag | Novel inhibitors of glutaminyl cyclase |
| EP2091948B1 (en) | 2006-11-30 | 2012-04-18 | Probiodrug AG | Novel inhibitors of glutaminyl cyclase |
| US7803810B2 (en) | 2007-03-09 | 2010-09-28 | Probiodrug Ag | Inhibitors |
| JP5667440B2 (ja) | 2007-04-18 | 2015-02-12 | プロビオドルグ エージー | グルタミニルシクラーゼ阻害剤としてのチオ尿素誘導体 |
| DK2142513T3 (da) | 2007-04-18 | 2014-06-10 | Probiodrug Ag | Nitrovinyl-diamin-derivater som glutaminyl-cyclase-inhibitorer |
| JP5675343B2 (ja) | 2007-04-18 | 2015-02-25 | プロビオドルグ エージー | グルタミニルシクラーゼ阻害剤としての尿素誘導体 |
| ES2478673T3 (es) | 2007-04-18 | 2014-07-22 | Probiodrug Ag | Derivados de tioxoquinazolinona como inhibidores de la glutaminil ciclasa |
| ES2474693T3 (es) | 2007-04-18 | 2014-07-09 | Probiodrug Ag | Derivados de ciano-guanidina como inhibidores de glutaminil ciclasa |
| US8188094B2 (en) | 2007-04-20 | 2012-05-29 | Probiodrug Ag | Inhibitors of glutaminyl cyclase |
| CA2703050A1 (en) * | 2007-10-15 | 2009-04-23 | Janssen Pharmaceutica Nv | Anti-amyloid antibodies, compositions, methods and uses |
| AT509611B1 (de) | 2008-06-12 | 2012-04-15 | Affiris Forschungs-Und Entwicklungs Gmbh | Vakzin |
| US8058405B2 (en) * | 2008-07-21 | 2011-11-15 | Probiodrug (AG) | Antibodies specific for N-terminal truncated and pyroglutamate modified amyloid-beta peptides |
| WO2010128139A1 (en) | 2009-05-08 | 2010-11-11 | Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin | Biomarkers and methods for diagnosing alzheimer's disease and/ or mild cognitive impairment |
| DK2448968T3 (da) * | 2009-06-29 | 2021-04-12 | Bioarctic Ab | ANTISTOFFER SOM ER SELEKTIVE FOR N-TERMINAL-TRUNKEREDE AMYLOID-ß PROTOFIBRILLER/OLIGOMERER |
-
2012
- 2012-03-16 MX MX2013010571A patent/MX343873B/es active IP Right Grant
- 2012-03-16 CN CN201280013607.2A patent/CN103459421B/zh not_active Expired - Fee Related
- 2012-03-16 AU AU2012228236A patent/AU2012228236B2/en not_active Ceased
- 2012-03-16 EP EP12708855.7A patent/EP2686346B1/en active Active
- 2012-03-16 EA EA201301029A patent/EA032054B1/ru not_active IP Right Cessation
- 2012-03-16 DK DK12708855.7T patent/DK2686346T3/en active
- 2012-03-16 WO PCT/EP2012/054629 patent/WO2012123562A1/en not_active Ceased
- 2012-03-16 SG SG2013062286A patent/SG192805A1/en unknown
- 2012-03-16 BR BR112013023211-0A patent/BR112013023211B1/pt not_active IP Right Cessation
- 2012-03-16 US US13/422,583 patent/US8809508B2/en active Active
- 2012-03-16 CA CA2828433A patent/CA2828433C/en active Active
- 2012-03-16 KR KR1020137023118A patent/KR102020072B1/ko not_active Expired - Fee Related
- 2012-03-16 JP JP2013558453A patent/JP6220675B2/ja not_active Expired - Fee Related
-
2013
- 2013-08-07 ZA ZA2013/05946A patent/ZA201305946B/en unknown
- 2013-08-07 IL IL227847A patent/IL227847A0/en active IP Right Grant
-
2014
- 2014-05-19 US US14/280,919 patent/US9657089B2/en not_active Expired - Fee Related
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