JP2015535820A5 - - Google Patents
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- JP2015535820A5 JP2015535820A5 JP2015532387A JP2015532387A JP2015535820A5 JP 2015535820 A5 JP2015535820 A5 JP 2015535820A5 JP 2015532387 A JP2015532387 A JP 2015532387A JP 2015532387 A JP2015532387 A JP 2015532387A JP 2015535820 A5 JP2015535820 A5 JP 2015535820A5
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- Prior art keywords
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- hcdr3
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- Prior art date
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261702834P | 2012-09-19 | 2012-09-19 | |
| US61/702,834 | 2012-09-19 | ||
| PCT/EP2013/069302 WO2014044686A1 (en) | 2012-09-19 | 2013-09-17 | Kir3dl2 binding agents |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015535820A JP2015535820A (ja) | 2015-12-17 |
| JP2015535820A5 true JP2015535820A5 (enExample) | 2016-10-27 |
| JP6507097B2 JP6507097B2 (ja) | 2019-04-24 |
Family
ID=49226157
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015532387A Active JP6507097B2 (ja) | 2012-09-19 | 2013-09-17 | Ｋｉｒ３ｄｌ２結合剤 |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US10577419B2 (enExample) |
| EP (1) | EP2897980B1 (enExample) |
| JP (1) | JP6507097B2 (enExample) |
| CN (1) | CN104640880B (enExample) |
| AU (1) | AU2013320360B2 (enExample) |
| BR (1) | BR112015006060B1 (enExample) |
| CA (1) | CA2881765C (enExample) |
| DK (1) | DK2897980T3 (enExample) |
| ES (1) | ES2770399T3 (enExample) |
| IL (1) | IL237220B (enExample) |
| MX (1) | MX369148B (enExample) |
| RU (1) | RU2682449C2 (enExample) |
| WO (1) | WO2014044686A1 (enExample) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2379598B1 (en) * | 2009-01-19 | 2015-03-11 | Innate Pharma | Anti-kir3d antibodies |
| CA2881765C (en) | 2012-09-19 | 2024-02-13 | Innate Pharma | Kir3dl2 binding agents |
| ES2878749T3 (es) * | 2013-02-20 | 2021-11-19 | Innate Pharma | Un compuesto que se une específicamente a KIR3DL2 para el uso en el tratamiento de linfoma de células T periférico |
| CN106132989B (zh) | 2014-03-14 | 2020-06-19 | 先天制药公司 | 具有增加的稳定性的人源化抗体 |
| US10519234B2 (en) | 2014-06-27 | 2019-12-31 | Innate Pharma | NKp46 binding proteins |
| DK3160994T3 (da) | 2014-06-27 | 2025-05-05 | Innate Pharma | Multispecifikke antigenbindende proteiner |
| WO2016030488A1 (en) * | 2014-08-27 | 2016-03-03 | Innate Pharma | Treatment of celiac disease |
| WO2016199097A1 (en) * | 2015-06-10 | 2016-12-15 | National Research Council Of Canada | Carbonic anhydrase ix-specific antibodies and uses thereof |
| CA2990518A1 (en) | 2015-06-23 | 2016-12-29 | Innate Pharma | Multispecific nk engager proteins |
| US20200048345A1 (en) | 2015-12-28 | 2020-02-13 | Innate Pharma | Multispecific antigen binding proteins |
| WO2017156423A2 (en) * | 2016-03-11 | 2017-09-14 | Integrated Biotherapeutics, Inc. | Broadly protective antibody cocktails for treatment of filovirus hemorrhagic fever |
| US10858431B2 (en) * | 2016-06-30 | 2020-12-08 | Trellis Bioscience, Llc | Monoclonal antibodies targeting killer immunoglobulin-like receptor (KIR) family signaling |
| KR20190068602A (ko) | 2016-10-21 | 2019-06-18 | 이나뜨 파르마 | 항-kir3dl2 작용제에 의한 치료 |
| US20190322767A1 (en) | 2016-12-23 | 2019-10-24 | Innate Pharma | Heterodimeric antigen binding proteins |
| EP3579879A4 (en) * | 2017-02-09 | 2020-12-16 | Memorial Sloan Kettering Cancer Center | ANTI-BODY ANTI-KIR3DL1 |
| CA3064443A1 (en) * | 2017-05-24 | 2018-11-29 | Development Center For Biotechnology | Humanized antibodies against globo h and uses thereof in cancer treatments |
| US10947316B2 (en) * | 2017-06-15 | 2021-03-16 | Development Center For Biotechnology | Antibody-drug conjugates containing anti-Globo H antibodies and uses thereof |
| CA3068056A1 (en) * | 2017-06-22 | 2018-12-27 | Development Center For Biotechnology | Asymmetric heterodimeric fc-scfv fusion anti-globo h and anti-cd3 bispecifc antibody and uses thereof in cancer therapy |
| EP3713959A1 (en) | 2017-11-21 | 2020-09-30 | Innate Pharma | Multispecific antigen binding proteins |
| JP7359390B2 (ja) * | 2018-02-09 | 2023-10-11 | 国立大学法人大阪大学 | チクングニアウイルスに対する抗体またはその抗原結合断片、およびその用途 |
| WO2020035345A1 (en) | 2018-08-14 | 2020-02-20 | Innate Pharma | Treatment of colorectal cancer by a combination of an anti-mica antibody and an anti-nkg2a antibody |
| BR112021014236A2 (pt) | 2019-01-22 | 2021-09-28 | Innate Pharma | Anticorpo, composição farmacêutica, kit e método para predizer ou avaliar a eficácia |
| CN110950960B (zh) * | 2019-11-26 | 2021-05-14 | 中国农业大学 | 基于高通量测序和杂合杂交瘤技术的小分子化合物抗体的制备方法 |
| CA3172697A1 (en) * | 2020-03-23 | 2021-09-30 | Ruth Yin-Zong LAN | Anti-ccr8 antibodies for treating cancer |
| MX2023009100A (es) | 2021-02-03 | 2023-09-25 | Mozart Therapeutics Inc | Agentes aglutinantes y métodos para usar los mismos. |
| US20240199750A1 (en) | 2021-03-26 | 2024-06-20 | Innate Pharma | Multispecific proteins comprising an nkp46-binding site, a cancer antgienge binding site fused to a cytokine for nk cell engaging |
| WO2022214432A1 (en) | 2021-04-05 | 2022-10-13 | Innate Pharma | Immunohistochemistry methods and kir3dl2-specific reagents |
| WO2022258691A1 (en) | 2021-06-09 | 2022-12-15 | Innate Pharma | Multispecific proteins binding to nkg2d, a cytokine receptor, a tumour antigen and cd16a |
| EP4351733A1 (en) | 2021-06-09 | 2024-04-17 | Innate Pharma | Multispecific antibodies binding to cd20, nkp46, cd16 and conjugated to il-2 |
| WO2022258678A1 (en) | 2021-06-09 | 2022-12-15 | Innate Pharma | Multispecific proteins binding to nkp30, a cytokine receptor, a tumour antigen and cd16a |
| KR20240019297A (ko) | 2021-06-09 | 2024-02-14 | 이나뜨 파르마 에스.에이. | Nkp46, 사이토카인 수용체, 종양 항원 및 cd16a 에 결합하는 다중특이적 단백질 |
| CN113248609B (zh) * | 2021-07-14 | 2021-09-10 | 深圳市盛波尔生命科学技术有限责任公司 | 针对再生胰岛衍生蛋白1α的抗体组合以及包含其的检测试剂盒 |
| KR20240040098A (ko) * | 2021-07-30 | 2024-03-27 | 알.피.쉐러 테크놀러지즈 엘엘씨 | 넥틴-4에 특이적인 항체 및 항체 접합체 및 이의 사용방법 |
| WO2023076876A1 (en) | 2021-10-26 | 2023-05-04 | Mozart Therapeutics, Inc. | Modulation of immune responses to viral vectors |
| JP2025532464A (ja) | 2022-09-15 | 2025-10-01 | アビディキュア アイピー ビー．ブイ． | Ｎｋ細胞の腫瘍標的化のための多重特異性抗原結合タンパク質及びその使用 |
| WO2024251884A1 (en) | 2023-06-09 | 2024-12-12 | Innate Pharma | Nk cell engager proteins comprising anti-cd20 and ant-nkp46 antibody, linked to il-2 in treatment of r/r b-nhl |
| CN117801108B (zh) * | 2023-12-06 | 2024-06-07 | 无锡傲锐东源生物科技有限公司 | 抗人mdm2蛋白单克隆抗体及其杂交瘤细胞株和应用 |
| WO2025191133A1 (en) | 2024-03-15 | 2025-09-18 | Avidicure Ip B.V. | Il-21 muteins, fusion proteins comprising the same and uses thereof |
| WO2025191136A1 (en) | 2024-03-15 | 2025-09-18 | Avidicure Ip B.V. | Muteins of 4-1bb ligand extracellular domain, fusion proteins comprising the same and uses thereof |
| WO2025191139A1 (en) | 2024-03-15 | 2025-09-18 | Avidicure Ip B.V. | Conjugates of her2-specific antigen binding proteins and cytokines |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004528824A (ja) | 2000-12-18 | 2004-09-24 | アーンスティテュ ナシオナール ド ラ サント エ ド ラ ルシェルシェ メディカル（イー．エンヌ．エス．ウー．エール．エンム．） | 皮膚ｔ細胞リンパ腫（ｃｔｃｌ）の新規な診断及び治療法 |
| KR20060079180A (ko) * | 2003-07-02 | 2006-07-05 | 노보 노르디스크 에이/에스 | Ｎｋ 세포 활성을 조절하기 위한 조성물 및 방법 |
| EP2379598B1 (en) * | 2009-01-19 | 2015-03-11 | Innate Pharma | Anti-kir3d antibodies |
| WO2011027310A1 (en) * | 2009-09-03 | 2011-03-10 | Koninklijke Philips Electronics N.V. | Novel tumor markers |
| WO2012047294A2 (en) * | 2010-10-06 | 2012-04-12 | Ludwig Institute For Cancer Research Ltd | Antibodies directed against hla-b27 homodimers and methods and uses thereof in diagnosis and therapy |
| CA2881765C (en) | 2012-09-19 | 2024-02-13 | Innate Pharma | Kir3dl2 binding agents |
| EP2897979B1 (en) * | 2012-09-19 | 2019-02-13 | Innate Pharma | Kir3dl2 binding agents |
| ES2878749T3 (es) | 2013-02-20 | 2021-11-19 | Innate Pharma | Un compuesto que se une específicamente a KIR3DL2 para el uso en el tratamiento de linfoma de células T periférico |
| US20160130346A1 (en) * | 2013-05-29 | 2016-05-12 | Institut National De La Sante Et De La Recherche Medicale | Kir3dl2 is a biomarker and a therapeutic target useful for respectively preventing and treating a subset of cutaneous and non-cutaneous peripheral t-cell lymphomas |
| CN106132989B (zh) | 2014-03-14 | 2020-06-19 | 先天制药公司 | 具有增加的稳定性的人源化抗体 |
| KR20190068602A (ko) | 2016-10-21 | 2019-06-18 | 이나뜨 파르마 | 항-kir3dl2 작용제에 의한 치료 |
-
2013
- 2013-09-17 CA CA2881765A patent/CA2881765C/en active Active
- 2013-09-17 MX MX2015003476A patent/MX369148B/es active IP Right Grant
- 2013-09-17 CN CN201380048468.1A patent/CN104640880B/zh active Active
- 2013-09-17 EP EP13765703.7A patent/EP2897980B1/en active Active
- 2013-09-17 RU RU2015104760A patent/RU2682449C2/ru active
- 2013-09-17 DK DK13765703.7T patent/DK2897980T3/da active
- 2013-09-17 ES ES13765703T patent/ES2770399T3/es active Active
- 2013-09-17 AU AU2013320360A patent/AU2013320360B2/en active Active
- 2013-09-17 WO PCT/EP2013/069302 patent/WO2014044686A1/en not_active Ceased
- 2013-09-17 JP JP2015532387A patent/JP6507097B2/ja active Active
- 2013-09-17 BR BR112015006060-9A patent/BR112015006060B1/pt active IP Right Grant
-
2015
- 2015-02-12 IL IL237220A patent/IL237220B/en active IP Right Grant
- 2015-03-19 US US14/662,349 patent/US10577419B2/en active Active
-
2020
- 2020-02-28 US US16/804,018 patent/US11858990B2/en active Active
-
2023
- 2023-12-27 US US18/396,776 patent/US20240124579A1/en active Pending
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