JP2015535820A5 - - Google Patents

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Publication number
JP2015535820A5
JP2015535820A5 JP2015532387A JP2015532387A JP2015535820A5 JP 2015535820 A5 JP2015535820 A5 JP 2015535820A5 JP 2015532387 A JP2015532387 A JP 2015532387A JP 2015532387 A JP2015532387 A JP 2015532387A JP 2015535820 A5 JP2015535820 A5 JP 2015535820A5
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JP
Japan
Prior art keywords
seq
antibody
hcdr1
hcdr3
hcdr2
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JP2015532387A
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English (en)
Japanese (ja)
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JP6507097B2 (ja
JP2015535820A (ja
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Priority claimed from PCT/EP2013/069302 external-priority patent/WO2014044686A1/en
Publication of JP2015535820A publication Critical patent/JP2015535820A/ja
Publication of JP2015535820A5 publication Critical patent/JP2015535820A5/ja
Application granted granted Critical
Publication of JP6507097B2 publication Critical patent/JP6507097B2/ja
Active legal-status Critical Current
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JP2015532387A 2012-09-19 2013-09-17 Kir3dl2結合剤 Active JP6507097B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261702834P 2012-09-19 2012-09-19
US61/702,834 2012-09-19
PCT/EP2013/069302 WO2014044686A1 (en) 2012-09-19 2013-09-17 Kir3dl2 binding agents

Publications (3)

Publication Number Publication Date
JP2015535820A JP2015535820A (ja) 2015-12-17
JP2015535820A5 true JP2015535820A5 (enExample) 2016-10-27
JP6507097B2 JP6507097B2 (ja) 2019-04-24

Family

ID=49226157

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015532387A Active JP6507097B2 (ja) 2012-09-19 2013-09-17 Kir3dl2結合剤

Country Status (13)

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US (3) US10577419B2 (enExample)
EP (1) EP2897980B1 (enExample)
JP (1) JP6507097B2 (enExample)
CN (1) CN104640880B (enExample)
AU (1) AU2013320360B2 (enExample)
BR (1) BR112015006060B1 (enExample)
CA (1) CA2881765C (enExample)
DK (1) DK2897980T3 (enExample)
ES (1) ES2770399T3 (enExample)
IL (1) IL237220B (enExample)
MX (1) MX369148B (enExample)
RU (1) RU2682449C2 (enExample)
WO (1) WO2014044686A1 (enExample)

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RU2682449C2 (ru) 2012-09-19 2019-03-19 Иннейт Фарма Связывающие kir3dl2 агенты
DK3896088T3 (da) 2013-02-20 2025-09-29 Innate Pharma Behandling af perifert t-cellelymfom
EP3116908B1 (en) 2014-03-14 2019-06-26 Innate Pharma Humanized kir3dl2 antibodies
AU2015279321B2 (en) 2014-06-27 2021-03-04 Innate Pharma, S.A. Multispecific antigen binding proteins
JP6822849B2 (ja) 2014-06-27 2021-01-27 イナート・ファルマ・ソシエテ・アノニムInnate Pharma Pharma S.A. 多重特異的NKp46結合タンパク質
WO2016030488A1 (en) * 2014-08-27 2016-03-03 Innate Pharma Treatment of celiac disease
US10487153B2 (en) 2015-06-10 2019-11-26 National Research Council Of Canada Carbonic anhydrase IX-specific antibodies and uses thereof
JP6840682B2 (ja) 2015-06-23 2021-03-10 イナート・ファルマ・ソシエテ・アノニムInnate Pharma Pharma S.A. 多重特異的抗原結合タンパク質
AU2016284871B2 (en) 2015-06-23 2022-09-29 Innate Pharma Multispecific NK engager proteins
WO2017156423A2 (en) * 2016-03-11 2017-09-14 Integrated Biotherapeutics, Inc. Broadly protective antibody cocktails for treatment of filovirus hemorrhagic fever
US10858431B2 (en) * 2016-06-30 2020-12-08 Trellis Bioscience, Llc Monoclonal antibodies targeting killer immunoglobulin-like receptor (KIR) family signaling
WO2018073363A1 (en) 2016-10-21 2018-04-26 Innate Pharma Treatment with anti-kir3dl2 agents
EP3559032A1 (en) 2016-12-23 2019-10-30 Innate Pharma Heterodimeric antigen binding proteins
WO2018148223A1 (en) * 2017-02-09 2018-08-16 Memorial Sloan Kettering Cancer Center Anti-kir3dl1 antibodies
US10781265B2 (en) * 2017-05-24 2020-09-22 Development Center For Biotechnology Humanized antibodies against Globo H and uses thereof in cancer treatments
EP3638306A4 (en) * 2017-06-15 2020-07-01 Development Center for Biotechnology ANTIBODY DRUG CONJUGATES CONTAINING ANTI-GLOBO H ANTIBODIES AND USES THEREOF
US20180371089A1 (en) * 2017-06-22 2018-12-27 Development Center For Biotechnology Asymmetric heterodimeric fc-scfv fusion anti-globo h and anti-cd3 bispecific antibody and uses thereof in caner therapy
EP3713959A1 (en) 2017-11-21 2020-09-30 Innate Pharma Multispecific antigen binding proteins
WO2019156223A1 (ja) * 2018-02-09 2019-08-15 国立大学法人大阪大学 チクングニアウイルスに対する抗体またはその抗原結合断片、およびその用途
WO2020035345A1 (en) 2018-08-14 2020-02-20 Innate Pharma Treatment of colorectal cancer by a combination of an anti-mica antibody and an anti-nkg2a antibody
BR112021014236A2 (pt) 2019-01-22 2021-09-28 Innate Pharma Anticorpo, composição farmacêutica, kit e método para predizer ou avaliar a eficácia
EP4037712A4 (en) 2019-10-04 2023-11-01 Albert Einstein College of Medicine KIR3DL3 IS AN IMMUNE SYSTEM INHIBITANT RECEPTOR AND USES THEREOF
CN110950960B (zh) * 2019-11-26 2021-05-14 中国农业大学 基于高通量测序和杂合杂交瘤技术的小分子化合物抗体的制备方法
AU2021244200A1 (en) * 2020-03-23 2022-11-24 Bristol-Myers Squibb Company Anti-CCR8 antibodies for treating cancer
CN113817052A (zh) * 2020-06-19 2021-12-21 南京金斯瑞生物科技有限公司 抗SARS-CoV-2核衣壳蛋白单克隆抗体及其制备方法和用途
AU2022218137A1 (en) 2021-02-03 2023-08-24 Mozart Therapeutics, Inc. Binding agents and methods of using the same
CN117321087A (zh) 2021-03-26 2023-12-29 先天制药公司 包含与细胞因子融合用于nk细胞衔接的nkp46结合位点、癌抗原结合位点的多特异性蛋白质
WO2022214432A1 (en) 2021-04-05 2022-10-13 Innate Pharma Immunohistochemistry methods and kir3dl2-specific reagents
WO2022258691A1 (en) 2021-06-09 2022-12-15 Innate Pharma Multispecific proteins binding to nkg2d, a cytokine receptor, a tumour antigen and cd16a
CN117616050A (zh) 2021-06-09 2024-02-27 先天制药公司 与nkp46、细胞因子受体、肿瘤抗原和cd16a结合的多特异性蛋白质
WO2022258678A1 (en) 2021-06-09 2022-12-15 Innate Pharma Multispecific proteins binding to nkp30, a cytokine receptor, a tumour antigen and cd16a
KR20240019786A (ko) 2021-06-09 2024-02-14 이나뜨 파르마 에스.에이. Cd20, nkp46, cd16에 결합하고 il-2에 접합된 다중특이적 항체
CN113248609B (zh) * 2021-07-14 2021-09-10 深圳市盛波尔生命科学技术有限责任公司 针对再生胰岛衍生蛋白1α的抗体组合以及包含其的检测试剂盒
KR20240040098A (ko) * 2021-07-30 2024-03-27 알.피.쉐러 테크놀러지즈 엘엘씨 넥틴-4에 특이적인 항체 및 항체 접합체 및 이의 사용방법
WO2023076876A1 (en) 2021-10-26 2023-05-04 Mozart Therapeutics, Inc. Modulation of immune responses to viral vectors
EP4587122A1 (en) 2022-09-15 2025-07-23 Avidicure IP B.V. Multispecific antigen binding proteins for stimulating nk cells and use thereof
WO2024251884A1 (en) 2023-06-09 2024-12-12 Innate Pharma Nk cell engager proteins comprising anti-cd20 and ant-nkp46 antibody, linked to il-2 in treatment of r/r b-nhl
CN117801108B (zh) * 2023-12-06 2024-06-07 无锡傲锐东源生物科技有限公司 抗人mdm2蛋白单克隆抗体及其杂交瘤细胞株和应用
WO2025191133A1 (en) 2024-03-15 2025-09-18 Avidicure Ip B.V. Il-21 muteins, fusion proteins comprising the same and uses thereof
WO2025191136A1 (en) 2024-03-15 2025-09-18 Avidicure Ip B.V. Muteins of 4-1bb ligand extracellular domain, fusion proteins comprising the same and uses thereof
WO2025191139A1 (en) 2024-03-15 2025-09-18 Avidicure Ip B.V. Conjugates of her2-specific antigen binding proteins and cytokines
WO2025245386A1 (en) * 2024-05-23 2025-11-27 La Jolla Institute For Immunology Kir3dl2 as an anti-cancer target
WO2026087748A1 (en) 2024-10-24 2026-04-30 Avidicure Ip B.V. Multispecific antigen binding proteins for the expansion of γδ t cells and use thereof

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AU1922902A (en) * 2000-12-18 2002-07-01 Inst Nat Sante Rech Med Novel means for the diagnosis and therapy of CTCL
HRP20120845T1 (hr) * 2003-07-02 2012-11-30 Innate Pharma Protutijela za pan-kir2dl nk-receptor i njihova uporaba u dijagnostici i lijeäśenju
EP2379598B1 (en) 2009-01-19 2015-03-11 Innate Pharma Anti-kir3d antibodies
WO2011027310A1 (en) * 2009-09-03 2011-03-10 Koninklijke Philips Electronics N.V. Novel tumor markers
WO2012047294A2 (en) * 2010-10-06 2012-04-12 Ludwig Institute For Cancer Research Ltd Antibodies directed against hla-b27 homodimers and methods and uses thereof in diagnosis and therapy
RU2682449C2 (ru) 2012-09-19 2019-03-19 Иннейт Фарма Связывающие kir3dl2 агенты
CA2881764C (en) 2012-09-19 2022-08-16 Innate Pharma Kir3dl2 binding agents
DK3896088T3 (da) 2013-02-20 2025-09-29 Innate Pharma Behandling af perifert t-cellelymfom
US20160130346A1 (en) * 2013-05-29 2016-05-12 Institut National De La Sante Et De La Recherche Medicale Kir3dl2 is a biomarker and a therapeutic target useful for respectively preventing and treating a subset of cutaneous and non-cutaneous peripheral t-cell lymphomas
EP3116908B1 (en) 2014-03-14 2019-06-26 Innate Pharma Humanized kir3dl2 antibodies
WO2018073363A1 (en) 2016-10-21 2018-04-26 Innate Pharma Treatment with anti-kir3dl2 agents

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