MX343873B - Ensayo de diagnostico de anticuerpo. - Google Patents
Ensayo de diagnostico de anticuerpo.Info
- Publication number
- MX343873B MX343873B MX2013010571A MX2013010571A MX343873B MX 343873 B MX343873 B MX 343873B MX 2013010571 A MX2013010571 A MX 2013010571A MX 2013010571 A MX2013010571 A MX 2013010571A MX 343873 B MX343873 B MX 343873B
- Authority
- MX
- Mexico
- Prior art keywords
- antibody assay
- diagnostic antibody
- diagnostic
- amyloidosis
- diagnosis
- Prior art date
Links
- 238000003556 assay Methods 0.000 title abstract 3
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 206010002022 amyloidosis Diseases 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4709—Amyloid plaque core protein
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2821—Alzheimer
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Genetics & Genomics (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161453449P | 2011-03-16 | 2011-03-16 | |
| PCT/EP2012/054629 WO2012123562A1 (en) | 2011-03-16 | 2012-03-16 | Diagnostic antibody assay |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2013010571A MX2013010571A (es) | 2013-12-02 |
| MX343873B true MX343873B (es) | 2016-11-25 |
Family
ID=45833428
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2013010571A MX343873B (es) | 2011-03-16 | 2012-03-16 | Ensayo de diagnostico de anticuerpo. |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US8809508B2 (enExample) |
| EP (1) | EP2686346B1 (enExample) |
| JP (1) | JP6220675B2 (enExample) |
| KR (1) | KR102020072B1 (enExample) |
| CN (1) | CN103459421B (enExample) |
| AU (1) | AU2012228236B2 (enExample) |
| BR (1) | BR112013023211B1 (enExample) |
| CA (1) | CA2828433C (enExample) |
| DK (1) | DK2686346T3 (enExample) |
| EA (1) | EA032054B1 (enExample) |
| IL (1) | IL227847A0 (enExample) |
| MX (1) | MX343873B (enExample) |
| SG (1) | SG192805A1 (enExample) |
| WO (1) | WO2012123562A1 (enExample) |
| ZA (1) | ZA201305946B (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014140279A1 (en) | 2013-03-15 | 2014-09-18 | Probiodrug Ag | Novel inhibitors |
| EP3234611A1 (en) | 2014-12-19 | 2017-10-25 | Probiodrug AG | Novel method for the detection of pglu-abeta peptides |
| EP3262070A4 (en) * | 2015-02-24 | 2018-07-25 | Rpeptide, LLC | Anti-amyloid-beta antibodies |
| KR102786380B1 (ko) * | 2015-07-16 | 2025-03-26 | 비보리온 테라퓨틱스 엔.브이. | 항-피로글루타메이트화된 아밀로이드 베타 인간화 항체 |
| GB201910697D0 (en) * | 2019-07-26 | 2019-09-11 | Binding Site Group Ltd | Lonisation control |
| JP2022550017A (ja) * | 2019-10-01 | 2022-11-30 | レプリゲン・コーポレーション | 流体におけるタンパク質濃度の決定 |
| KR102790945B1 (ko) * | 2022-09-23 | 2025-04-04 | 경성대학교 산학협력단 | 베타-아밀로이드 42를 이용한 치매 진단 방법 및 이를 이용한 치매 진단 키트 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4737456A (en) | 1985-05-09 | 1988-04-12 | Syntex (U.S.A.) Inc. | Reducing interference in ligand-receptor binding assays |
| JP4804690B2 (ja) * | 1999-12-08 | 2011-11-02 | インテレクト・ニューロサイエンシズ・インコーポレーテッド | 免疫原としてのキメラペプチド、それに対する抗体、およびキメラペプチドまたは抗体を用いた免疫法 |
| US7117096B2 (en) * | 2001-04-17 | 2006-10-03 | Abmaxis, Inc. | Structure-based selection and affinity maturation of antibody library |
| CA2487528A1 (en) | 2002-07-24 | 2004-02-12 | Innogenetics N.V. | Prevention, treatment and diagnosis of diseases associated with beta-amyloid formation and/or aggregation |
| WO2004029629A1 (en) | 2002-09-27 | 2004-04-08 | Janssen Pharmaceutica N.V. | N-11 truncated amyloid-beta nomoclonal antibodies, compositions, methods and uses |
| KR101099206B1 (ko) | 2004-02-05 | 2011-12-27 | 프로비오드룩 아게 | 신규한 글루타미닐 시클라제 저해제 |
| ES2259270B1 (es) | 2005-03-09 | 2007-11-01 | Consejo Superior De Investigaciones Cientificas | Metodo de diagnostico in vitro de la enfermedad de alzheimer mediante un anticuerpo monoclonal. |
| EP2043687A4 (en) | 2006-06-29 | 2010-03-17 | Centocor Ortho Biotech Inc | ANTI-AMYLOID ANTIBODIES, COMPOSITIONS, METHODS AND USES |
| JP5456479B2 (ja) | 2006-11-09 | 2014-03-26 | プロビオドルグ エージー | グルタミニルシクラーゼの新規阻害剤 |
| WO2008055945A1 (en) | 2006-11-09 | 2008-05-15 | Probiodrug Ag | 3-hydr0xy-1,5-dihydr0-pyrr0l-2-one derivatives as inhibitors of glutaminyl cyclase for the treatment of ulcer, cancer and other diseases |
| US7741354B2 (en) | 2006-11-09 | 2010-06-22 | Probiodrug Ag | Inhibitors of glutaminyl cyclase |
| EP2091948B1 (en) | 2006-11-30 | 2012-04-18 | Probiodrug AG | Novel inhibitors of glutaminyl cyclase |
| US7803810B2 (en) | 2007-03-09 | 2010-09-28 | Probiodrug Ag | Inhibitors |
| WO2008128982A1 (en) | 2007-04-18 | 2008-10-30 | Probiodrug Ag | Thioxoquinazolinone derivatives as glutaminyl cyclase inhibitors |
| US9512082B2 (en) | 2007-04-18 | 2016-12-06 | Probiodrug Ag | Inhibitors of glutaminyl cyclase |
| US8772508B2 (en) | 2007-04-18 | 2014-07-08 | Probiodrug Ag | Inhibitors of glutaminyl cyclase |
| DK2160380T3 (da) | 2007-04-18 | 2014-06-30 | Probiodrug Ag | Cyano-guanidin derivater som glutaminyl cyclase inhibitorer |
| US9656991B2 (en) | 2007-04-18 | 2017-05-23 | Probiodrug Ag | Inhibitors of glutaminyl cyclase |
| JP5676249B2 (ja) | 2007-04-20 | 2015-02-25 | プロビオドルグ エージー | グルタミニルシクラーゼ阻害剤としてのアミノピリジン誘導体 |
| EP2211886A4 (en) * | 2007-10-15 | 2011-07-27 | Centocor Ortho Biotech Inc | HUMAN ANTI-AMYLOID ANTIBODIES, COMPOSITIONS, PROCESSES AND APPLICATIONS |
| AT506820B1 (de) | 2008-06-12 | 2011-07-15 | Affiris Forschungs Und Entwicklungs Gmbh | Vakzine gegen alzheimer-krankheit |
| JP5828762B2 (ja) * | 2008-07-21 | 2015-12-09 | プロビオドルグ エージー | 診断用抗体アッセイ |
| WO2010128139A1 (en) * | 2009-05-08 | 2010-11-11 | Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin | Biomarkers and methods for diagnosing alzheimer's disease and/ or mild cognitive impairment |
| PT2448968T (pt) * | 2009-06-29 | 2021-04-30 | Bioarctic Ab | ANTICORPOS SELETIVOS PARA PROTOFIBRILAS/OLIGÓMEROS DE ß- AMILOIDE TRUNCADA EM N-TERMINAL |
-
2012
- 2012-03-16 BR BR112013023211-0A patent/BR112013023211B1/pt not_active IP Right Cessation
- 2012-03-16 CA CA2828433A patent/CA2828433C/en active Active
- 2012-03-16 US US13/422,583 patent/US8809508B2/en active Active
- 2012-03-16 WO PCT/EP2012/054629 patent/WO2012123562A1/en not_active Ceased
- 2012-03-16 AU AU2012228236A patent/AU2012228236B2/en not_active Ceased
- 2012-03-16 DK DK12708855.7T patent/DK2686346T3/en active
- 2012-03-16 JP JP2013558453A patent/JP6220675B2/ja not_active Expired - Fee Related
- 2012-03-16 SG SG2013062286A patent/SG192805A1/en unknown
- 2012-03-16 CN CN201280013607.2A patent/CN103459421B/zh not_active Expired - Fee Related
- 2012-03-16 MX MX2013010571A patent/MX343873B/es active IP Right Grant
- 2012-03-16 KR KR1020137023118A patent/KR102020072B1/ko not_active Expired - Fee Related
- 2012-03-16 EA EA201301029A patent/EA032054B1/ru not_active IP Right Cessation
- 2012-03-16 EP EP12708855.7A patent/EP2686346B1/en active Active
-
2013
- 2013-08-07 IL IL227847A patent/IL227847A0/en active IP Right Grant
- 2013-08-07 ZA ZA2013/05946A patent/ZA201305946B/en unknown
-
2014
- 2014-05-19 US US14/280,919 patent/US9657089B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| IL227847A0 (en) | 2013-09-30 |
| EA201301029A1 (ru) | 2014-05-30 |
| CN103459421A (zh) | 2013-12-18 |
| EP2686346B1 (en) | 2016-12-14 |
| CA2828433C (en) | 2020-08-04 |
| US9657089B2 (en) | 2017-05-23 |
| AU2012228236B2 (en) | 2016-10-27 |
| BR112013023211A2 (pt) | 2016-11-22 |
| KR102020072B1 (ko) | 2019-11-04 |
| JP2014509860A (ja) | 2014-04-24 |
| SG192805A1 (en) | 2013-09-30 |
| US20120237529A1 (en) | 2012-09-20 |
| WO2012123562A1 (en) | 2012-09-20 |
| BR112013023211B1 (pt) | 2022-11-08 |
| CN103459421B (zh) | 2017-07-14 |
| EP2686346A1 (en) | 2014-01-22 |
| KR20140006019A (ko) | 2014-01-15 |
| EA032054B1 (ru) | 2019-04-30 |
| JP6220675B2 (ja) | 2017-11-01 |
| CA2828433A1 (en) | 2012-09-20 |
| AU2012228236A1 (en) | 2013-10-03 |
| MX2013010571A (es) | 2013-12-02 |
| DK2686346T3 (en) | 2017-03-27 |
| NZ614217A (en) | 2015-12-24 |
| US8809508B2 (en) | 2014-08-19 |
| US20140255414A1 (en) | 2014-09-11 |
| ZA201305946B (en) | 2014-10-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |