JP2014507123A - 心臓病状に対する薬効のサロゲートマーカーとしての血中miRNA - Google Patents

心臓病状に対する薬効のサロゲートマーカーとしての血中miRNA Download PDF

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JP2014507123A
JP2014507123A JP2013544771A JP2013544771A JP2014507123A JP 2014507123 A JP2014507123 A JP 2014507123A JP 2013544771 A JP2013544771 A JP 2013544771A JP 2013544771 A JP2013544771 A JP 2013544771A JP 2014507123 A JP2014507123 A JP 2014507123A
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mir
hsa
mirna
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heart failure
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JP2014507123A5 (enExample
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ヴァン ローイ,エヴァ
ディッキンソン,ブレント
セト,アニタ
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ミラゲン セラピューティクス
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JP2013544771A 2010-12-15 2011-12-15 心臓病状に対する薬効のサロゲートマーカーとしての血中miRNA Pending JP2014507123A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US42345610P 2010-12-15 2010-12-15
US61/423,456 2010-12-15
US201161495220P 2011-06-09 2011-06-09
US61/495,220 2011-06-09
US201161538585P 2011-09-23 2011-09-23
US61/538,585 2011-09-23
PCT/US2011/065120 WO2012083004A2 (en) 2010-12-15 2011-12-15 Blood-borne mirnas as surrogate markers of drug efficacy for cardiac conditions

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JP2014507123A true JP2014507123A (ja) 2014-03-27
JP2014507123A5 JP2014507123A5 (enExample) 2015-02-05

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US (1) US20140024700A1 (enExample)
EP (1) EP2652146A2 (enExample)
JP (1) JP2014507123A (enExample)
CN (1) CN103370424A (enExample)
AU (1) AU2011343719A1 (enExample)
CA (1) CA2818174A1 (enExample)
WO (1) WO2012083004A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021097669A (ja) * 2015-05-08 2021-07-01 エージェンシー フォー サイエンス,テクノロジー アンド リサーチ 慢性心不全の診断と予後予測の方法
WO2021250969A1 (ja) * 2020-06-08 2021-12-16 国立大学法人東海国立大学機構 マイクロrnaの慢性期心機能改善治療への利用

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ITRM20110685A1 (it) 2011-12-23 2013-06-24 Internat Ct For Genetic En Gineering And Microrna per la rigenerazione cardiaca attraverso l induzione della proliferazione dei miociti cardiaci
EP2925884B1 (en) * 2012-11-27 2018-01-31 Luxembourg Institute of Health Compositions and methods for evaluating heart failure
CN103290116B (zh) * 2013-05-16 2016-09-07 南京市妇幼保健院 一种与胎儿先天性心脏病相关的母体血清/血浆miRNA标志物及其应用
US20160251720A1 (en) * 2013-11-01 2016-09-01 The Trustees Of Columbia University In The City New York MicroRNA PROFILES IN HEART FAILURE: METHODS AND SYSTEMS FOR DETECTION AND USE
CN103667459A (zh) * 2013-11-26 2014-03-26 上海中医药大学附属岳阳中西医结合医院 微小核苷酸在高血压诊断和制备降血压药物中的应用
CN104740648B (zh) 2013-12-27 2020-02-14 江苏命码生物科技有限公司 miRNA-214抑制剂在抑制调节性T细胞中的应用
CN104031987B (zh) * 2014-05-12 2016-08-31 贵州省人民医院 miRNA在心肌纤维化疾病治疗中的应用
US10131952B2 (en) 2014-05-14 2018-11-20 Ohio State Innovation Foundation MIRNA biomarkers for monitoring bone marrow reconstitution
EP3034623A1 (en) * 2014-12-18 2016-06-22 Centro de Investigación Biomédica en Red (CIBER) Method for predicting response to continuous positive air pressure treatment
EP3292213A1 (en) * 2015-05-04 2018-03-14 Academisch Medisch Centrum Biomarkers for the detection of aspirin insensitivity
CN105999302A (zh) * 2016-06-13 2016-10-12 上海市东方医院 一种miRNA-21a抑制剂及在制备延缓心肌梗死的药物中的用途
CN107557464B (zh) * 2016-07-02 2021-06-04 上海市公共卫生临床中心 用于干扰素治疗慢性乙型肝炎早期病毒学反应的预测模型及检测试剂盒
CN106399473B (zh) * 2016-08-23 2019-12-06 南京大学 检测和评价力量训练效果的miRNA标志物或其组合及其应用
US20180193270A1 (en) 2016-11-29 2018-07-12 PureTech Health LLC Exosomes for delivery of therapeutic agents
CN106729757A (zh) * 2017-03-08 2017-05-31 复旦大学附属中山医院 miR‑378抑制心肌肥厚和心肌纤维化并诊断心力衰竭的用途
CN107858419A (zh) * 2017-11-10 2018-03-30 青岛大学 miRNA的应用、应用其的产品及检测方法
CN107881173A (zh) * 2017-11-16 2018-04-06 上海市东方医院 一种miRNA‑21小分子及其用途
CN108004316A (zh) * 2018-01-09 2018-05-08 青岛大学 用于预测急性心肌梗死风险的试剂盒
CN108866177B (zh) * 2018-05-31 2021-05-28 李继承 hsa-miRNA-423-5p和hsa-miRNA-423-5p抑制剂的用途
CN110055322A (zh) * 2019-05-12 2019-07-26 青岛大学 用于急性心肌梗死诊断的循环miRNA标志物及其应用
CN112410414B (zh) * 2020-10-09 2022-07-08 嘉兴市妇幼保健院 孕妇血清外泌体miRNA标志物在制备胎儿先心病早期诊断产品中的应用及试剂盒
CN113943792A (zh) * 2021-11-02 2022-01-18 石河子大学 检测miRNA表达量的试剂在制备诊断或预后哈萨克族高血压的试剂或试剂盒中的应用
CN116726038A (zh) * 2022-03-04 2023-09-12 南京大学 来源于棕榈炭的microRNA或其组合在制备止血药物中的应用

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021097669A (ja) * 2015-05-08 2021-07-01 エージェンシー フォー サイエンス,テクノロジー アンド リサーチ 慢性心不全の診断と予後予測の方法
JP7336792B2 (ja) 2015-05-08 2023-09-01 エージェンシー フォー サイエンス,テクノロジー アンド リサーチ 慢性心不全の診断と予後予測の方法
WO2021250969A1 (ja) * 2020-06-08 2021-12-16 国立大学法人東海国立大学機構 マイクロrnaの慢性期心機能改善治療への利用

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EP2652146A2 (en) 2013-10-23
WO2012083004A2 (en) 2012-06-21
CA2818174A1 (en) 2012-06-21
CN103370424A (zh) 2013-10-23
AU2011343719A1 (en) 2013-04-11
US20140024700A1 (en) 2014-01-23

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