JP2014507123A - 心臓病状に対する薬効のサロゲートマーカーとしての血中miRNA - Google Patents
心臓病状に対する薬効のサロゲートマーカーとしての血中miRNA Download PDFInfo
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| PCT/US2011/065120 WO2012083004A2 (en) | 2010-12-15 | 2011-12-15 | Blood-borne mirnas as surrogate markers of drug efficacy for cardiac conditions |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2021097669A (ja) * | 2015-05-08 | 2021-07-01 | エージェンシー フォー サイエンス,テクノロジー アンド リサーチ | 慢性心不全の診断と予後予測の方法 |
| WO2021250969A1 (ja) * | 2020-06-08 | 2021-12-16 | 国立大学法人東海国立大学機構 | マイクロrnaの慢性期心機能改善治療への利用 |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITRM20110685A1 (it) | 2011-12-23 | 2013-06-24 | Internat Ct For Genetic En Gineering And | Microrna per la rigenerazione cardiaca attraverso l induzione della proliferazione dei miociti cardiaci |
| EP2925884B1 (en) * | 2012-11-27 | 2018-01-31 | Luxembourg Institute of Health | Compositions and methods for evaluating heart failure |
| CN103290116B (zh) * | 2013-05-16 | 2016-09-07 | 南京市妇幼保健院 | 一种与胎儿先天性心脏病相关的母体血清/血浆miRNA标志物及其应用 |
| US20160251720A1 (en) * | 2013-11-01 | 2016-09-01 | The Trustees Of Columbia University In The City New York | MicroRNA PROFILES IN HEART FAILURE: METHODS AND SYSTEMS FOR DETECTION AND USE |
| CN103667459A (zh) * | 2013-11-26 | 2014-03-26 | 上海中医药大学附属岳阳中西医结合医院 | 微小核苷酸在高血压诊断和制备降血压药物中的应用 |
| CN104740648B (zh) | 2013-12-27 | 2020-02-14 | 江苏命码生物科技有限公司 | miRNA-214抑制剂在抑制调节性T细胞中的应用 |
| CN104031987B (zh) * | 2014-05-12 | 2016-08-31 | 贵州省人民医院 | miRNA在心肌纤维化疾病治疗中的应用 |
| US10131952B2 (en) | 2014-05-14 | 2018-11-20 | Ohio State Innovation Foundation | MIRNA biomarkers for monitoring bone marrow reconstitution |
| EP3034623A1 (en) * | 2014-12-18 | 2016-06-22 | Centro de Investigación Biomédica en Red (CIBER) | Method for predicting response to continuous positive air pressure treatment |
| EP3292213A1 (en) * | 2015-05-04 | 2018-03-14 | Academisch Medisch Centrum | Biomarkers for the detection of aspirin insensitivity |
| CN105999302A (zh) * | 2016-06-13 | 2016-10-12 | 上海市东方医院 | 一种miRNA-21a抑制剂及在制备延缓心肌梗死的药物中的用途 |
| CN107557464B (zh) * | 2016-07-02 | 2021-06-04 | 上海市公共卫生临床中心 | 用于干扰素治疗慢性乙型肝炎早期病毒学反应的预测模型及检测试剂盒 |
| CN106399473B (zh) * | 2016-08-23 | 2019-12-06 | 南京大学 | 检测和评价力量训练效果的miRNA标志物或其组合及其应用 |
| US20180193270A1 (en) | 2016-11-29 | 2018-07-12 | PureTech Health LLC | Exosomes for delivery of therapeutic agents |
| CN106729757A (zh) * | 2017-03-08 | 2017-05-31 | 复旦大学附属中山医院 | miR‑378抑制心肌肥厚和心肌纤维化并诊断心力衰竭的用途 |
| CN107858419A (zh) * | 2017-11-10 | 2018-03-30 | 青岛大学 | miRNA的应用、应用其的产品及检测方法 |
| CN107881173A (zh) * | 2017-11-16 | 2018-04-06 | 上海市东方医院 | 一种miRNA‑21小分子及其用途 |
| CN108004316A (zh) * | 2018-01-09 | 2018-05-08 | 青岛大学 | 用于预测急性心肌梗死风险的试剂盒 |
| CN108866177B (zh) * | 2018-05-31 | 2021-05-28 | 李继承 | hsa-miRNA-423-5p和hsa-miRNA-423-5p抑制剂的用途 |
| CN110055322A (zh) * | 2019-05-12 | 2019-07-26 | 青岛大学 | 用于急性心肌梗死诊断的循环miRNA标志物及其应用 |
| CN112410414B (zh) * | 2020-10-09 | 2022-07-08 | 嘉兴市妇幼保健院 | 孕妇血清外泌体miRNA标志物在制备胎儿先心病早期诊断产品中的应用及试剂盒 |
| CN113943792A (zh) * | 2021-11-02 | 2022-01-18 | 石河子大学 | 检测miRNA表达量的试剂在制备诊断或预后哈萨克族高血压的试剂或试剂盒中的应用 |
| CN116726038A (zh) * | 2022-03-04 | 2023-09-12 | 南京大学 | 来源于棕榈炭的microRNA或其组合在制备止血药物中的应用 |
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| WO2010091204A1 (en) * | 2009-02-04 | 2010-08-12 | Board Of Regents, The University Of Texas System | Dual targeting of mir-208 and mir-499 in the treatment of cardiac disorders |
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| US20090306181A1 (en) * | 2006-09-29 | 2009-12-10 | Children's Medical Center Corporation | Compositions and methods for evaluating and treating heart failure |
| US20090105174A1 (en) * | 2007-04-20 | 2009-04-23 | Amgen Inc. | Nucleic acids hybridizable to micro rna and precursors thereof |
| CN101802227B (zh) * | 2007-07-18 | 2014-12-10 | 科罗拉多大学董事会法人团体 | 非衰竭与衰竭的人心脏中微小rna的差异表达 |
| JP2010154843A (ja) * | 2008-06-27 | 2010-07-15 | Keio Gijuku | バイオマーカーとしてのマイクロrnaを用いた婦人科がんの診断・治療選択 |
| WO2010130351A1 (en) * | 2009-05-15 | 2010-11-18 | Bayer Schering Pharma Ag | Micrornas as biomarkers and therapeutic targets for heart failure |
| CN101643791A (zh) * | 2009-09-04 | 2010-02-10 | 哈尔滨医科大学 | microRNA-328及其反义核苷酸在诊断、防治心脏疾病中的用途 |
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2011
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- 2011-12-15 WO PCT/US2011/065120 patent/WO2012083004A2/en not_active Ceased
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- 2011-12-15 AU AU2011343719A patent/AU2011343719A1/en not_active Abandoned
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- 2011-12-15 US US13/994,622 patent/US20140024700A1/en not_active Abandoned
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010091204A1 (en) * | 2009-02-04 | 2010-08-12 | Board Of Regents, The University Of Texas System | Dual targeting of mir-208 and mir-499 in the treatment of cardiac disorders |
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| JPN6015051104; Circ. Cardiovasc. Genet., 2010, Vol. 3, pp. 426-435 * |
| JPN6015051105; Clin. Chem., 2010, Vol. 56, No. 7, pp. 1183-1185 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2021097669A (ja) * | 2015-05-08 | 2021-07-01 | エージェンシー フォー サイエンス,テクノロジー アンド リサーチ | 慢性心不全の診断と予後予測の方法 |
| JP7336792B2 (ja) | 2015-05-08 | 2023-09-01 | エージェンシー フォー サイエンス,テクノロジー アンド リサーチ | 慢性心不全の診断と予後予測の方法 |
| WO2021250969A1 (ja) * | 2020-06-08 | 2021-12-16 | 国立大学法人東海国立大学機構 | マイクロrnaの慢性期心機能改善治療への利用 |
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| Publication number | Publication date |
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| WO2012083004A3 (en) | 2012-11-29 |
| EP2652146A2 (en) | 2013-10-23 |
| WO2012083004A2 (en) | 2012-06-21 |
| CA2818174A1 (en) | 2012-06-21 |
| CN103370424A (zh) | 2013-10-23 |
| AU2011343719A1 (en) | 2013-04-11 |
| US20140024700A1 (en) | 2014-01-23 |
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