JP2014506259A5 - - Google Patents

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Publication number
JP2014506259A5
JP2014506259A5 JP2013548861A JP2013548861A JP2014506259A5 JP 2014506259 A5 JP2014506259 A5 JP 2014506259A5 JP 2013548861 A JP2013548861 A JP 2013548861A JP 2013548861 A JP2013548861 A JP 2013548861A JP 2014506259 A5 JP2014506259 A5 JP 2014506259A5
Authority
JP
Japan
Prior art keywords
seq
cdr
ligand
antibody
binds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2013548861A
Other languages
English (en)
Japanese (ja)
Other versions
JP2014506259A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2012/050633 external-priority patent/WO2012098113A1/en
Publication of JP2014506259A publication Critical patent/JP2014506259A/ja
Publication of JP2014506259A5 publication Critical patent/JP2014506259A5/ja
Withdrawn legal-status Critical Current

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JP2013548861A 2011-01-17 2012-01-17 Il−21リガンド Withdrawn JP2014506259A (ja)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
EP11151073 2011-01-17
EP11151073.1 2011-01-17
US201161434989P 2011-01-21 2011-01-21
US61/434,989 2011-01-21
EP11168328.0 2011-05-31
EP11168328 2011-05-31
US201161493002P 2011-06-03 2011-06-03
US61/493,002 2011-06-03
EP11187212.3 2011-10-31
EP11187212 2011-10-31
PCT/EP2012/050633 WO2012098113A1 (en) 2011-01-17 2012-01-17 Il-21 ligands

Publications (2)

Publication Number Publication Date
JP2014506259A JP2014506259A (ja) 2014-03-13
JP2014506259A5 true JP2014506259A5 (enExample) 2015-03-05

Family

ID=46515179

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013548861A Withdrawn JP2014506259A (ja) 2011-01-17 2012-01-17 Il−21リガンド

Country Status (5)

Country Link
US (1) US20130323259A1 (enExample)
EP (1) EP2665750A1 (enExample)
JP (1) JP2014506259A (enExample)
CN (1) CN103443124A (enExample)
WO (1) WO2012098113A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2006340750B2 (en) 2005-11-28 2013-03-07 Zymogenetics, Inc. IL-21 antagonists
EP2746293A1 (en) 2012-12-21 2014-06-25 Novo Nordisk A/S Anti-IL21 antibodies for use in the treatment of cardiovascular diseases
US20140178395A1 (en) 2012-12-21 2014-06-26 Novo Nordisk A/S Treatment of nephropathy
WO2015118119A1 (en) * 2014-02-07 2015-08-13 Novo Nordisk A/S Antibody process
AR099625A1 (es) 2014-03-21 2016-08-03 Lilly Co Eli Anticuerpos de il-21
WO2015169789A1 (en) 2014-05-07 2015-11-12 Novo Nordisk A/S Treatment of diabetes type 1 using glp-1 and anti-il-21
JP6449338B2 (ja) 2014-06-06 2019-01-09 ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company グルココルチコイド誘導腫瘍壊死因子受容体(gitr)に対する抗体およびその使用
JP6812364B2 (ja) 2015-06-03 2021-01-13 ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company 癌診断用抗gitr抗体
CN108738324B (zh) 2015-11-19 2022-06-21 百时美施贵宝公司 抗糖皮质激素诱导的肿瘤坏死因子受体(gitr)抗体及其用途
KR20200006115A (ko) 2017-05-16 2020-01-17 브리스톨-마이어스 스큅 컴퍼니 항-gitr 효능제 항체에 의한 암의 치료
WO2021119482A1 (en) 2019-12-13 2021-06-17 Progenity, Inc. Ingestible device for delivery of therapeutic agent to the gastrointestinal tract
US12012441B2 (en) 2020-10-26 2024-06-18 Neptune Biosciences Llc Engineered human IL-21 cytokines and methods for using the same

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2506665T3 (es) 1999-12-23 2014-10-13 Genentech, Inc. Polipéptidos homólogos IL-17 e IL-17R y usos terapéuticos de los mismos
SG177012A1 (en) * 2002-05-20 2012-01-30 Abmaxis Inc Generation and selection of protein library in silico
CN102746399B (zh) * 2002-12-24 2016-03-02 里纳特神经系统学公司 抗ngf抗体及其使用方法
ITRM20040586A1 (it) * 2004-11-29 2005-02-28 Giuliani Spa Epitopi antigenici dell'interleuchina-21, anticorpi relativi e loro uso in campo medico.
AU2006340750B2 (en) * 2005-11-28 2013-03-07 Zymogenetics, Inc. IL-21 antagonists
JP2009520468A (ja) * 2005-12-23 2009-05-28 ヴィヴェンティア バイオテック インコーポレーティッド 融合タンパク質ライブラリーの作製法およびスクリーニング法、ならびにそれらの使用
WO2009047360A1 (en) * 2007-10-11 2009-04-16 Novo Nordisk A/S Il-21 antibodies
EP2217268B1 (en) * 2007-12-07 2016-05-04 ZymoGenetics, Inc. Anti-human il-21 monoclonal antibodies
WO2009132821A1 (en) * 2008-04-28 2009-11-05 Giuliani International Limited Interleukin (il-21) binding proteins and methods of making and using same
US8193321B2 (en) * 2008-09-03 2012-06-05 Genentech, Inc. Multispecific antibodies
CA2760525A1 (en) * 2009-04-29 2010-11-04 Mark Cunningham Toll-like receptor 3 antagonists

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