|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US4737456A
(en)
|
1985-05-09 |
1988-04-12 |
Syntex (U.S.A.) Inc. |
Reducing interference in ligand-receptor binding assays
|
|
US4676980A
(en)
|
1985-09-23 |
1987-06-30 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Target specific cross-linked heteroantibodies
|
|
US6548640B1
(en)
|
1986-03-27 |
2003-04-15 |
Btg International Limited |
Altered antibodies
|
|
IL85035A0
(en)
|
1987-01-08 |
1988-06-30 |
Int Genetic Eng |
Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
|
|
WO1988007089A1
(en)
|
1987-03-18 |
1988-09-22 |
Medical Research Council |
Altered antibodies
|
|
US5606040A
(en)
|
1987-10-30 |
1997-02-25 |
American Cyanamid Company |
Antitumor and antibacterial substituted disulfide derivatives prepared from compounds possessing a methyl-trithio group
|
|
US5770701A
(en)
|
1987-10-30 |
1998-06-23 |
American Cyanamid Company |
Process for preparing targeted forms of methyltrithio antitumor agents
|
|
EP0368684B2
(en)
|
1988-11-11 |
2004-09-29 |
Medical Research Council |
Cloning immunoglobulin variable domain sequences.
|
|
DE3920358A1
(de)
|
1989-06-22 |
1991-01-17 |
Behringwerke Ag |
Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
|
|
US5208020A
(en)
|
1989-10-25 |
1993-05-04 |
Immunogen Inc. |
Cytotoxic agents comprising maytansinoids and their therapeutic use
|
|
CA2026147C
(en)
|
1989-10-25 |
2006-02-07 |
Ravi J. Chari |
Cytotoxic agents comprising maytansinoids and their therapeutic use
|
|
US5959177A
(en)
|
1989-10-27 |
1999-09-28 |
The Scripps Research Institute |
Transgenic plants expressing assembled secretory antibodies
|
|
US6075181A
(en)
|
1990-01-12 |
2000-06-13 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US6150584A
(en)
|
1990-01-12 |
2000-11-21 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US5112596A
(en)
|
1990-04-23 |
1992-05-12 |
Alkermes, Inc. |
Method for increasing blood-brain barrier permeability by administering a bradykinin agonist of blood-brain barrier permeability
|
|
US5268164A
(en)
|
1990-04-23 |
1993-12-07 |
Alkermes, Inc. |
Increasing blood-brain barrier permeability with permeabilizer peptides
|
|
US5200339A
(en)
|
1990-08-17 |
1993-04-06 |
Abraham Carmela R |
Proteases causing abnormal degradation of amyloid β-protein precursor
|
|
WO1992003542A1
(en)
|
1990-08-17 |
1992-03-05 |
Boston University |
PROTEASES CAUSING ABNORMAL DEGRADATION OF AMYLOID β-PROTEIN PRECURSOR
|
|
US5770429A
(en)
|
1990-08-29 |
1998-06-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
CA2405246A1
(en)
|
1990-12-03 |
1992-06-11 |
Genentech, Inc. |
Enrichment method for variant proteins with alterred binding properties
|
|
US5571894A
(en)
|
1991-02-05 |
1996-11-05 |
Ciba-Geigy Corporation |
Recombinant antibodies specific for a growth factor receptor
|
|
EP1400536A1
(en)
|
1991-06-14 |
2004-03-24 |
Genentech Inc. |
Method for making humanized antibodies
|
|
GB9114948D0
(en)
|
1991-07-11 |
1991-08-28 |
Pfizer Ltd |
Process for preparing sertraline intermediates
|
|
WO1993006217A1
(en)
|
1991-09-19 |
1993-04-01 |
Genentech, Inc. |
EXPRESSION IN E. COLI OF ANTIBODY FRAGMENTS HAVING AT LEAST A CYSTEINE PRESENT AS A FREE THIOL, USE FOR THE PRODUCTION OF BIFUNCTIONAL F(ab')2 ANTIBODIES
|
|
FI941572L
(fi)
|
1991-10-07 |
1994-05-27 |
Oncologix Inc |
Anti-erbB-2-monoklonaalisten vasta-aineiden yhdistelmä ja käyttömenetelmä
|
|
WO1993008829A1
(en)
|
1991-11-04 |
1993-05-13 |
The Regents Of The University Of California |
Compositions that mediate killing of hiv-infected cells
|
|
AU675929B2
(en)
|
1992-02-06 |
1997-02-27 |
Curis, Inc. |
Biosynthetic binding protein for cancer marker
|
|
ATE191853T1
(de)
|
1992-07-27 |
2000-05-15 |
Us Health |
Zielgerichte liposome zur blut-hirne schranke
|
|
MD1367C2
(ro)
|
1992-11-13 |
2000-11-30 |
Idec Pharmaceuticals Corporation |
Metode de tratament al limfomului celulelor B, anticorpi anti-CD20, hibridom.
|
|
US5635483A
(en)
|
1992-12-03 |
1997-06-03 |
Arizona Board Of Regents Acting On Behalf Of Arizona State University |
Tumor inhibiting tetrapeptide bearing modified phenethyl amides
|
|
US5780588A
(en)
|
1993-01-26 |
1998-07-14 |
Arizona Board Of Regents |
Elucidation and synthesis of selected pentapeptides
|
|
AU691811B2
(en)
|
1993-06-16 |
1998-05-28 |
Celltech Therapeutics Limited |
Antibodies
|
|
US5773001A
(en)
|
1994-06-03 |
1998-06-30 |
American Cyanamid Company |
Conjugates of methyltrithio antitumor agents and intermediates for their synthesis
|
|
US5789199A
(en)
|
1994-11-03 |
1998-08-04 |
Genentech, Inc. |
Process for bacterial production of polypeptides
|
|
US5840523A
(en)
|
1995-03-01 |
1998-11-24 |
Genetech, Inc. |
Methods and compositions for secretion of heterologous polypeptides
|
|
US5731168A
(en)
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
|
US5869046A
(en)
|
1995-04-14 |
1999-02-09 |
Genentech, Inc. |
Altered polypeptides with increased half-life
|
|
US5712374A
(en)
|
1995-06-07 |
1998-01-27 |
American Cyanamid Company |
Method for the preparation of substantiallly monomeric calicheamicin derivative/carrier conjugates
|
|
US5942400A
(en)
|
1995-06-07 |
1999-08-24 |
Elan Pharmaceuticals, Inc. |
Assays for detecting β-secretase
|
|
US6221645B1
(en)
|
1995-06-07 |
2001-04-24 |
Elan Pharmaceuticals, Inc. |
β-secretase antibody
|
|
US5714586A
(en)
|
1995-06-07 |
1998-02-03 |
American Cyanamid Company |
Methods for the preparation of monomeric calicheamicin derivative/carrier conjugates
|
|
US6329163B1
(en)
|
1995-06-07 |
2001-12-11 |
Elan Pharmaceuticals, Inc. |
Assays for detecting β-secretase inhibition
|
|
US5744346A
(en)
|
1995-06-07 |
1998-04-28 |
Athena Neurosciences, Inc. |
β-secretase
|
|
US6267958B1
(en)
|
1995-07-27 |
2001-07-31 |
Genentech, Inc. |
Protein formulation
|
|
GB9603256D0
(en)
|
1996-02-16 |
1996-04-17 |
Wellcome Found |
Antibodies
|
|
AU1684097A
(en)
|
1996-12-11 |
1998-07-03 |
Athena Neurosciences, Inc. |
Beta-secretase isolated from human 293 cells
|
|
GB9701684D0
(en)
|
1997-01-28 |
1997-03-19 |
Smithkline Beecham Plc |
Novel compounds
|
|
US6171586B1
(en)
|
1997-06-13 |
2001-01-09 |
Genentech, Inc. |
Antibody formulation
|
|
ATE296315T1
(de)
|
1997-06-24 |
2005-06-15 |
Genentech Inc |
Galactosylierte glykoproteine enthaltende zusammensetzungen und verfahren zur deren herstellung
|
|
US6040498A
(en)
|
1998-08-11 |
2000-03-21 |
North Caroline State University |
Genetically engineered duckweed
|
|
WO1999022764A1
(en)
|
1997-10-31 |
1999-05-14 |
Genentech, Inc. |
Methods and compositions comprising glycoprotein glycoforms
|
|
US6610833B1
(en)
|
1997-11-24 |
2003-08-26 |
The Institute For Human Genetics And Biochemistry |
Monoclonal human natural antibodies
|
|
ES2375931T3
(es)
|
1997-12-05 |
2012-03-07 |
The Scripps Research Institute |
Humanización de anticuerpo murino.
|
|
US6194551B1
(en)
|
1998-04-02 |
2001-02-27 |
Genentech, Inc. |
Polypeptide variants
|
|
ES2292236T3
(es)
|
1998-04-02 |
2008-03-01 |
Genentech, Inc. |
Variantes de anticuerpos y sus fragmentos.
|
|
ES2434961T5
(es)
|
1998-04-20 |
2018-01-18 |
Roche Glycart Ag |
Ingeniería de glicosilación de anticuerpos para mejorar la citotoxicidad celular dependiente del anticuerpo
|
|
US6699671B1
(en)
|
1998-09-24 |
2004-03-02 |
Pharmacia & Upjohn Company |
Alzheimer's disease secretase, APP substrates therefor, and uses therefor
|
|
US7456007B1
(en)
|
1998-12-31 |
2008-11-25 |
Elan Pharmaceuticals, Inc. |
β-secretase enzyme compositions and methods
|
|
US7115410B1
(en)
|
1999-02-10 |
2006-10-03 |
Elan Pharmaceuticals, Inc. |
β-secretase enzyme compositions and methods
|
|
HU230769B1
(hu)
|
1999-01-15 |
2018-03-28 |
Genentech Inc. |
Módosított effektor-funkciójú polipeptid-változatok
|
|
US6737056B1
(en)
|
1999-01-15 |
2004-05-18 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
|
CN1390232A
(zh)
|
1999-02-10 |
2003-01-08 |
艾兰制药公司 |
人β分泌酶、抑制剂、其组合物和用途
|
|
WO2000058479A1
(en)
|
1999-03-26 |
2000-10-05 |
Amgen Inc. |
Beta secretase genes and polypeptides
|
|
EP1176195B1
(en)
|
1999-04-09 |
2013-05-22 |
Kyowa Hakko Kirin Co., Ltd. |
Method for controlling the activity of immunologically functional molecule
|
|
EP1196609A2
(en)
|
1999-06-28 |
2002-04-17 |
Oklahoma Medical Research Foundation |
Catalytically active recombinant memapsin and methods of use thereof
|
|
CN100427603C
(zh)
|
1999-10-04 |
2008-10-22 |
麦迪卡格公司 |
调控外源基因转录的方法
|
|
US7125978B1
(en)
|
1999-10-04 |
2006-10-24 |
Medicago Inc. |
Promoter for regulating expression of foreign genes
|
|
CA2388245C
(en)
|
1999-10-19 |
2012-01-10 |
Kyowa Kirin Co., Ltd. |
The use of serum-free adapted rat cells for producing heterologous polypeptides
|
|
GB9924957D0
(en)
|
1999-10-21 |
1999-12-22 |
Smithkline Beecham Plc |
Novel treatment
|
|
US7514408B1
(en)
|
1999-12-02 |
2009-04-07 |
Elan Pharmaceuticals, Inc. |
β-secretase enzyme compositions and methods
|
|
AU784983B2
(en)
|
1999-12-15 |
2006-08-17 |
Genentech Inc. |
Shotgun scanning, a combinatorial method for mapping functional protein epitopes
|
|
ATE344801T1
(de)
|
1999-12-29 |
2006-11-15 |
Immunogen Inc |
Doxorubicin- und daunorubicin-enthaltende, zytotoxische mittel und deren therapeutische anwendung
|
|
CN101289511A
(zh)
|
2000-04-11 |
2008-10-22 |
杰南技术公司 |
多价抗体及其应用
|
|
US7205120B2
(en)
|
2000-07-19 |
2007-04-17 |
Pharmacia & Upjohn Company |
Substrates and assays for β-secretase activity
|
|
US6514221B2
(en)
|
2000-07-27 |
2003-02-04 |
Brigham And Women's Hospital, Inc. |
Blood-brain barrier opening
|
|
US7630838B2
(en)
*
|
2000-09-22 |
2009-12-08 |
American Home Products Corporation |
Method for identifying agents that interact with beta-site APP cleaving enzyme (BACE)
|
|
US7064191B2
(en)
|
2000-10-06 |
2006-06-20 |
Kyowa Hakko Kogyo Co., Ltd. |
Process for purifying antibody
|
|
US6946292B2
(en)
|
2000-10-06 |
2005-09-20 |
Kyowa Hakko Kogyo Co., Ltd. |
Cells producing antibody compositions with increased antibody dependent cytotoxic activity
|
|
ES2639222T5
(es)
|
2000-10-06 |
2023-11-24 |
Kyowa Kirin Co Ltd |
Células que producen unas composiciones de anticuerpo
|
|
AU2002243391A1
(en)
*
|
2000-10-27 |
2002-06-24 |
The Johns Hopkins University School Of Medicine |
Beta-secretase transgenic organisms, anti-beta-secretase antibodies, and methods of use thereof
|
|
US6596541B2
(en)
|
2000-10-31 |
2003-07-22 |
Regeneron Pharmaceuticals, Inc. |
Methods of modifying eukaryotic cells
|
|
US20030083299A1
(en)
|
2000-11-04 |
2003-05-01 |
Ferguson Ian A. |
Non-invasive delivery of polypeptides through the blood-brain barrier
|
|
CN1487996B
(zh)
|
2000-11-30 |
2010-06-16 |
米德列斯公司 |
用于生产人类抗体的转基因转染色体啮齿动物
|
|
US7217556B1
(en)
|
2000-12-23 |
2007-05-15 |
Pfizer Inc |
Crystallization and structure determination of glycosylated human beta secretase, an enzyme implicated in Alzheimer's disease
|
|
US7601528B1
(en)
|
2000-12-23 |
2009-10-13 |
Elan Pharmaceuticals, Inc. |
Crystallization and structure determination of glycosylated human beta secretase, an enzyme implicated in alzheimer's disease
|
|
AU2002239727C1
(en)
|
2000-12-28 |
2005-12-22 |
Oklahoma Medical Research Foundation |
Inhibitors of memapsin 2 and use thereof
|
|
DE10121982B4
(de)
|
2001-05-05 |
2008-01-24 |
Lts Lohmann Therapie-Systeme Ag |
Nanopartikel aus Protein mit gekoppeltem Apolipoprotein E zur Überwindung der Blut-Hirn-Schranke und Verfahren zu ihrer Herstellung
|
|
US7384773B1
(en)
|
2001-05-10 |
2008-06-10 |
Pfizer Inc |
Crystal of HIV protease-cleaved human beta secretase and method for crystallization thereof
|
|
DE60229846D1
(de)
|
2001-05-22 |
2008-12-24 |
Merck & Co Inc |
Beta-secretase-substrat und seine verwendung
|
|
EP2180044A1
(en)
|
2001-08-03 |
2010-04-28 |
GlycArt Biotechnology AG |
Antibody glycosylation variants having increased anti-body-dependent cellular cytotoxicity
|
|
CA2464736A1
(en)
|
2001-10-23 |
2003-05-15 |
Oklahoma Medical Research Foundation |
Beta-secretase inhibitors and methods of use
|
|
HUP0600342A3
(en)
|
2001-10-25 |
2011-03-28 |
Genentech Inc |
Glycoprotein compositions
|
|
US20040093621A1
(en)
|
2001-12-25 |
2004-05-13 |
Kyowa Hakko Kogyo Co., Ltd |
Antibody composition which specifically binds to CD20
|
|
US20030224512A1
(en)
|
2002-05-31 |
2003-12-04 |
Isis Pharmaceuticals Inc. |
Antisense modulation of beta-site APP-cleaving enzyme expression
|
|
EA200401325A1
(ru)
|
2002-04-09 |
2005-04-28 |
Киова Хакко Когио Ко., Лтд. |
Клетки с модифицированным геномом
|
|
JP4832719B2
(ja)
|
2002-04-09 |
2011-12-07 |
協和発酵キリン株式会社 |
ＦｃγＲＩＩＩａ多型患者に適応する抗体組成物含有医薬
|
|
US20040259150A1
(en)
|
2002-04-09 |
2004-12-23 |
Kyowa Hakko Kogyo Co., Ltd. |
Method of enhancing of binding activity of antibody composition to Fcgamma receptor IIIa
|
|
US20040132140A1
(en)
|
2002-04-09 |
2004-07-08 |
Kyowa Hakko Kogyo Co., Ltd. |
Production process for antibody composition
|
|
CA2481920A1
(en)
|
2002-04-09 |
2003-10-16 |
Kyowa Hakko Kogyo Co., Ltd. |
Antibody composition-containing medicament
|
|
ATE503829T1
(de)
|
2002-04-09 |
2011-04-15 |
Kyowa Hakko Kirin Co Ltd |
Zelle mit erniedrigter oder deletierter aktivität eines am gdp-fucosetransport beteiligten proteins
|
|
US7166454B1
(en)
|
2002-05-24 |
2007-01-23 |
Schering Corporation |
Codon-optimized β-secretase and methods of refolding and processing
|
|
EP1513879B1
(en)
|
2002-06-03 |
2018-08-22 |
Genentech, Inc. |
Synthetic antibody phage libraries
|
|
EP2305710A3
(en)
*
|
2002-06-03 |
2013-05-29 |
Genentech, Inc. |
Synthetic antibody phage libraries
|
|
US7361740B2
(en)
|
2002-10-15 |
2008-04-22 |
Pdl Biopharma, Inc. |
Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
|
|
AU2003285892A1
(en)
|
2002-10-15 |
2004-05-04 |
Bristol-Myers Squibb Company |
Bace binding peptides and uses thereof
|
|
CN101284136A
(zh)
|
2002-12-03 |
2008-10-15 |
布朗歇特洛克菲勒神经科学研究所 |
传输物质穿过血脑屏障的人工低密度脂蛋白载体
|
|
EP3263596A1
(en)
|
2002-12-16 |
2018-01-03 |
Genentech, Inc. |
Immunoglobulin variants and uses thereof
|
|
CA2510003A1
(en)
|
2003-01-16 |
2004-08-05 |
Genentech, Inc. |
Synthetic antibody phage libraries
|
|
US7871607B2
(en)
|
2003-03-05 |
2011-01-18 |
Halozyme, Inc. |
Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases
|
|
US20060104968A1
(en)
|
2003-03-05 |
2006-05-18 |
Halozyme, Inc. |
Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminogly ycanases
|
|
EP1473362A1
(en)
|
2003-05-02 |
2004-11-03 |
Elan Pharmaceuticals, Inc. |
Glycosylation variants of BACE
|
|
CA2531684C
(en)
*
|
2003-07-22 |
2014-03-11 |
Crucell Holland B.V. |
Binding molecules against sars-coronavirus and uses thereof
|
|
US20050106667A1
(en)
*
|
2003-08-01 |
2005-05-19 |
Genentech, Inc |
Binding polypeptides with restricted diversity sequences
|
|
US7758859B2
(en)
*
|
2003-08-01 |
2010-07-20 |
Genentech, Inc. |
Anti-VEGF antibodies
|
|
WO2005014815A1
(en)
|
2003-08-08 |
2005-02-17 |
President And Fellows Of Harvard College |
siRNA BASED METHODS FOR TREATING ALZHEIMER’S DISEASE
|
|
US20080241884A1
(en)
|
2003-10-08 |
2008-10-02 |
Kenya Shitara |
Fused Protein Composition
|
|
JPWO2005035778A1
(ja)
|
2003-10-09 |
2006-12-21 |
協和醗酵工業株式会社 |
α１，６−フコシルトランスフェラーゼの機能を抑制するＲＮＡを用いた抗体組成物の製造法
|
|
US20070149763A1
(en)
|
2003-10-15 |
2007-06-28 |
Bristol-Myers Squibb Company |
Beta secretase exosite binding peptides and methods for identifying beta secretase modulators
|
|
ES2672640T3
(es)
|
2003-11-05 |
2018-06-15 |
Roche Glycart Ag |
Moléculas de unión a antígeno con afinidad de unión a receptores Fc y función efectora incrementadas
|
|
US7498298B2
(en)
|
2003-11-06 |
2009-03-03 |
Seattle Genetics, Inc. |
Monomethylvaline compounds capable of conjugation to ligands
|
|
JP2007510425A
(ja)
*
|
2003-11-06 |
2007-04-26 |
エグゾニ・テラピューティック・ソシエテ・アノニム |
ＢＡＣＥ４５５、ヒトβ−セクレターゼの選択的スプライシング変異体
|
|
US7413737B2
(en)
*
|
2003-11-14 |
2008-08-19 |
Massachusetts Institute Of Technology |
Anti-hydroxylase antibodies and uses thereof
|
|
WO2005053742A1
(ja)
|
2003-12-04 |
2005-06-16 |
Kyowa Hakko Kogyo Co., Ltd. |
抗体組成物を含有する医薬
|
|
CN1961003B
(zh)
|
2004-03-31 |
2013-03-27 |
健泰科生物技术公司 |
人源化抗TGF-β抗体
|
|
US7785903B2
(en)
|
2004-04-09 |
2010-08-31 |
Genentech, Inc. |
Variable domain library and uses
|
|
KR100891620B1
(ko)
|
2004-04-13 |
2009-04-02 |
에프. 호프만-라 로슈 아게 |
항-ｐ-셀렉틴 항체
|
|
TWI309240B
(en)
|
2004-09-17 |
2009-05-01 |
Hoffmann La Roche |
Anti-ox40l antibodies
|
|
KR101270829B1
(ko)
|
2004-09-23 |
2013-06-07 |
제넨테크, 인크. |
시스테인 유전자조작 항체 및 접합체
|
|
US20080220445A1
(en)
|
2004-10-01 |
2008-09-11 |
Takeda Pharmaceutical Company Limited |
Method of Screening Transmembrane Enzyme Inhibitory Substance
|
|
BRPI0515670A
(pt)
*
|
2004-10-04 |
2008-07-29 |
Genentech Inc |
anticorpos isolados e método de tratamento de uma doença associada com descontrole da sinalização do hgf/c-met
|
|
JO3000B1
(ar)
|
2004-10-20 |
2016-09-05 |
Genentech Inc |
مركبات أجسام مضادة .
|
|
AU2006279896A1
(en)
|
2005-08-10 |
2007-02-22 |
Oklahoma Medical Research Foundation |
Truncated memapsin 2 for use for treating Alzheimer's disease
|
|
EP1957531B1
(en)
|
2005-11-07 |
2016-04-13 |
Genentech, Inc. |
Binding polypeptides with diversified and consensus vh/vl hypervariable sequences
|
|
UA96139C2
(uk)
*
|
2005-11-08 |
2011-10-10 |
Дженентек, Інк. |
Антитіло до нейропіліну-1 (nrp1)
|
|
WO2007064919A2
(en)
|
2005-12-02 |
2007-06-07 |
Genentech, Inc. |
Binding polypeptides with restricted diversity sequences
|
|
AU2007248444B2
(en)
*
|
2006-01-05 |
2012-10-25 |
Genentech, Inc. |
Anti-EphB4 antibodies and methods using same
|
|
AR059096A1
(es)
*
|
2006-01-20 |
2008-03-12 |
Genentech Inc |
Anticuerpos anti- efrina -b2 y metodos que usan estos
|
|
JP2009536527A
(ja)
|
2006-05-09 |
2009-10-15 |
ジェネンテック・インコーポレーテッド |
最適化されたスキャフォールドを備えた結合ポリペプチド
|
|
ES2567402T3
(es)
*
|
2006-05-30 |
2016-04-22 |
Genentech, Inc. |
Anticuerpos anti CD22, sus inmunoconjugados y usos de los mismos
|
|
WO2008027236A2
(en)
|
2006-08-30 |
2008-03-06 |
Genentech, Inc. |
Multispecific antibodies
|
|
KR20140116546A
(ko)
|
2006-10-27 |
2014-10-02 |
제넨테크, 인크. |
항체 및 면역접합체 및 이들의 용도
|
|
US20100047232A1
(en)
*
|
2006-11-14 |
2010-02-25 |
Jasvinder Atwal |
Modulators of neuronal regeneration
|
|
US20080226635A1
(en)
|
2006-12-22 |
2008-09-18 |
Hans Koll |
Antibodies against insulin-like growth factor I receptor and uses thereof
|
|
AR065271A1
(es)
*
|
2007-02-09 |
2009-05-27 |
Genentech Inc |
Anticuerpos anti-robo4 y sus usos
|
|
JP5394246B2
(ja)
*
|
2007-03-30 |
2014-01-22 |
ジェネンテック， インコーポレイテッド |
抗体及びイムノコンジュゲートとこれらの使用方法
|
|
AU2008240673A1
(en)
|
2007-04-19 |
2008-10-30 |
Katholieke Universiteit Leuven, K.U. Leuven R & D |
Oligonucleotide compositions for the treatment of Alzheimer's disease
|
|
CN100592373C
(zh)
|
2007-05-25 |
2010-02-24 |
群康科技(深圳)有限公司 |
液晶显示面板驱动装置及其驱动方法
|
|
ES2563027T3
(es)
|
2008-01-07 |
2016-03-10 |
Amgen Inc. |
Método para fabricación de moléculas heterodímeras Fc de anticuerpos utilizando efectos de conducción electrostática
|
|
ES2447844T3
(es)
*
|
2008-04-03 |
2014-03-13 |
Vib Vzw |
Anticuerpos de dominio individual capaces de modular la actividad BACE1
|
|
WO2009155609A1
(en)
*
|
2008-06-20 |
2009-12-23 |
Oklahoma Medical Research Foundation |
IMMUNOGENIC MEMAPSIN 2 β-SECRETASE PEPTIDES AND METHODS OF USE
|
|
TW201019959A
(en)
*
|
2008-08-19 |
2010-06-01 |
Regeneron Pharma |
Human antibodies to human RANKL
|
|
US8790642B2
(en)
*
|
2008-08-29 |
2014-07-29 |
Genentech, Inc. |
Cross-reactive and bispecific anti-IL-17A/F antibodies
|
|
US20100233156A1
(en)
|
2009-03-09 |
2010-09-16 |
Georgetown University |
Treating Central Nervous System Injury with Beta and Gamma Secretase Inhibitors
|
|
WO2010146058A1
(en)
|
2009-06-15 |
2010-12-23 |
Vib Vzw |
Bace1 inhibitory antibodies
|
|
MX346500B
(es)
|
2010-11-10 |
2017-03-22 |
Genentech Inc * |
Metodos y composiciones para inmunoterapia para enfermedad neural.
|
|
AR084020A1
(es)
|
2010-11-30 |
2013-04-17 |
Genentech Inc |
Anticuerpos para el receptor de la barrera hematoencefalica de baja afinidad y sus usos
|
|
US20120282176A1
(en)
|
2011-04-20 |
2012-11-08 |
Roche Glycart Ag |
Method and Constructs for the pH Dependent Passage of the Blood-brain-barrier
|
|
AU2013266611B2
(en)
|
2012-05-21 |
2016-08-11 |
Genentech, Inc. |
Methods for improving safety of blood-brain barrier transport
|