JP2014111664A5 - - Google Patents
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- Publication number
- JP2014111664A5 JP2014111664A5 JP2014052426A JP2014052426A JP2014111664A5 JP 2014111664 A5 JP2014111664 A5 JP 2014111664A5 JP 2014052426 A JP2014052426 A JP 2014052426A JP 2014052426 A JP2014052426 A JP 2014052426A JP 2014111664 A5 JP2014111664 A5 JP 2014111664A5
- Authority
- JP
- Japan
- Prior art keywords
- weight
- citrus
- nobiletin
- plant tissue
- pharmaceutical product
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- VYFYYTLLBUKUHU-UHFFFAOYSA-N dopamine Chemical compound NCCC1=CC=C(O)C(O)=C1 VYFYYTLLBUKUHU-UHFFFAOYSA-N 0.000 claims 12
- OBIOZWXPDBWYHB-UHFFFAOYSA-N Nobiletin Natural products C1=CC(OC)=CC=C1C1=C(OC)C(=O)C2=C(OC)C(OC)=C(OC)C(OC)=C2O1 OBIOZWXPDBWYHB-UHFFFAOYSA-N 0.000 claims 6
- 235000020971 citrus fruits Nutrition 0.000 claims 6
- 229960003638 dopamine Drugs 0.000 claims 6
- MRIAQLRQZPPODS-UHFFFAOYSA-N nobiletin Chemical compound C1=C(OC)C(OC)=CC=C1C1=CC(=O)C2=C(OC)C(OC)=C(OC)C(OC)=C2O1 MRIAQLRQZPPODS-UHFFFAOYSA-N 0.000 claims 6
- 239000000825 pharmaceutical preparation Substances 0.000 claims 6
- 229940127557 pharmaceutical product Drugs 0.000 claims 6
- ULSUXBXHSYSGDT-UHFFFAOYSA-N tangeretin Chemical compound C1=CC(OC)=CC=C1C1=CC(=O)C2=C(OC)C(OC)=C(OC)C(OC)=C2O1 ULSUXBXHSYSGDT-UHFFFAOYSA-N 0.000 claims 6
- 241000196324 Embryophyta Species 0.000 claims 5
- 239000000284 extract Substances 0.000 claims 5
- 235000013305 food Nutrition 0.000 claims 4
- 230000001737 promoting effect Effects 0.000 claims 4
- 239000001100 (2S)-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chroman-4-one Substances 0.000 claims 3
- 241001672694 Citrus reticulata Species 0.000 claims 3
- QUQPHWDTPGMPEX-UHFFFAOYSA-N Hesperidine Natural products C1=C(O)C(OC)=CC=C1C1OC2=CC(OC3C(C(O)C(O)C(COC4C(C(O)C(O)C(C)O4)O)O3)O)=CC(O)=C2C(=O)C1 QUQPHWDTPGMPEX-UHFFFAOYSA-N 0.000 claims 3
- IECRXMSGDFIOEY-UHFFFAOYSA-N Tangeretin Natural products COC=1C(OC)=C(OC)C(OC)=C(C(C=2)=O)C=1OC=2C1=CC=C(O)C=C1 IECRXMSGDFIOEY-UHFFFAOYSA-N 0.000 claims 3
- QUQPHWDTPGMPEX-UTWYECKDSA-N aurantiamarin Natural products COc1ccc(cc1O)[C@H]1CC(=O)c2c(O)cc(O[C@@H]3O[C@H](CO[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4O)[C@@H](O)[C@H](O)[C@H]3O)cc2O1 QUQPHWDTPGMPEX-UTWYECKDSA-N 0.000 claims 3
- APSNPMVGBGZYAJ-GLOOOPAXSA-N clematine Natural products COc1cc(ccc1O)[C@@H]2CC(=O)c3c(O)cc(O[C@@H]4O[C@H](CO[C@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)cc3O2 APSNPMVGBGZYAJ-GLOOOPAXSA-N 0.000 claims 3
- VUYDGVRIQRPHFX-UHFFFAOYSA-N hesperidin Natural products COc1cc(ccc1O)C2CC(=O)c3c(O)cc(OC4OC(COC5OC(O)C(O)C(O)C5O)C(O)C(O)C4O)cc3O2 VUYDGVRIQRPHFX-UHFFFAOYSA-N 0.000 claims 3
- QUQPHWDTPGMPEX-QJBIFVCTSA-N hesperidin Chemical compound C1=C(O)C(OC)=CC=C1[C@H]1OC2=CC(O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@@H](CO[C@H]4[C@@H]([C@H](O)[C@@H](O)[C@H](C)O4)O)O3)O)=CC(O)=C2C(=O)C1 QUQPHWDTPGMPEX-QJBIFVCTSA-N 0.000 claims 3
- 229940025878 hesperidin Drugs 0.000 claims 3
- 239000004615 ingredient Substances 0.000 claims 3
- ARGKVCXINMKCAZ-UHFFFAOYSA-N neohesperidine Natural products C1=C(O)C(OC)=CC=C1C1OC2=CC(OC3C(C(O)C(O)C(CO)O3)OC3C(C(O)C(O)C(C)O3)O)=CC(O)=C2C(=O)C1 ARGKVCXINMKCAZ-UHFFFAOYSA-N 0.000 claims 3
- 241000207199 Citrus Species 0.000 claims 2
- 240000000513 Santalum album Species 0.000 claims 2
- 235000008632 Santalum album Nutrition 0.000 claims 2
- 244000273928 Zingiber officinale Species 0.000 claims 2
- 235000006886 Zingiber officinale Nutrition 0.000 claims 2
- 230000002708 enhancing effect Effects 0.000 claims 2
- 235000008397 ginger Nutrition 0.000 claims 2
- 241000411851 herbal medicine Species 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 230000028327 secretion Effects 0.000 claims 2
- 238000003809 water extraction Methods 0.000 claims 2
- 241000143060 Americamysis bahia Species 0.000 claims 1
- 244000248539 Asparagus cochinchinensis Species 0.000 claims 1
- 235000009292 Asparagus cochinchinensis Nutrition 0.000 claims 1
- 240000005220 Bischofia javanica Species 0.000 claims 1
- 235000010893 Bischofia javanica Nutrition 0.000 claims 1
- 241000544061 Cuculus canorus Species 0.000 claims 1
- 240000008067 Cucumis sativus Species 0.000 claims 1
- 235000010799 Cucumis sativus var sativus Nutrition 0.000 claims 1
- 244000000626 Daucus carota Species 0.000 claims 1
- 235000002767 Daucus carota Nutrition 0.000 claims 1
- 241000222336 Ganoderma Species 0.000 claims 1
- 235000011201 Ginkgo Nutrition 0.000 claims 1
- 244000194101 Ginkgo biloba Species 0.000 claims 1
- 235000008100 Ginkgo biloba Nutrition 0.000 claims 1
- 240000004670 Glycyrrhiza echinata Species 0.000 claims 1
- 235000001453 Glycyrrhiza echinata Nutrition 0.000 claims 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 claims 1
- 235000017382 Glycyrrhiza lepidota Nutrition 0.000 claims 1
- 208000020358 Learning disease Diseases 0.000 claims 1
- 208000026139 Memory disease Diseases 0.000 claims 1
- 241000736199 Paeonia Species 0.000 claims 1
- 235000006484 Paeonia officinalis Nutrition 0.000 claims 1
- 208000018737 Parkinson disease Diseases 0.000 claims 1
- 240000008154 Piper betle Species 0.000 claims 1
- 235000008180 Piper betle Nutrition 0.000 claims 1
- 244000007853 Sarothamnus scoparius Species 0.000 claims 1
- 244000269722 Thea sinensis Species 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000004503 fine granule Substances 0.000 claims 1
- 239000008187 granular material Substances 0.000 claims 1
- 229910052602 gypsum Inorganic materials 0.000 claims 1
- 239000010440 gypsum Substances 0.000 claims 1
- 235000015110 jellies Nutrition 0.000 claims 1
- 239000008274 jelly Substances 0.000 claims 1
- 201000003723 learning disability Diseases 0.000 claims 1
- 229940010454 licorice Drugs 0.000 claims 1
- 229940126601 medicinal product Drugs 0.000 claims 1
- 238000002156 mixing Methods 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
- 238000003786 synthesis reaction Methods 0.000 claims 1
- 239000006188 syrup Substances 0.000 claims 1
- 235000020357 syrup Nutrition 0.000 claims 1
- 239000003826 tablet Substances 0.000 claims 1
- 108010021724 tonin Proteins 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2014052426A JP5906267B2 (ja) | 2010-02-26 | 2014-03-14 | 学習・記憶障害および運動障害などを伴う中枢神経変性疾患を改善する乾燥植物組織および植物組織抽出物ならびにこれらを含有する医薬品および食品 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010042819 | 2010-02-26 | ||
| JP2010042819 | 2010-02-26 | ||
| JP2010126717 | 2010-06-02 | ||
| JP2010126717 | 2010-06-02 | ||
| JP2010270578 | 2010-12-03 | ||
| JP2010270578 | 2010-12-03 | ||
| JP2014052426A JP5906267B2 (ja) | 2010-02-26 | 2014-03-14 | 学習・記憶障害および運動障害などを伴う中枢神経変性疾患を改善する乾燥植物組織および植物組織抽出物ならびにこれらを含有する医薬品および食品 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012501889A Division JP5503726B2 (ja) | 2010-02-26 | 2011-02-25 | 学習・記憶障害および運動障害などを伴う中枢神経変性疾患を改善する乾燥植物組織および植物組織抽出物ならびにこれらを含有する医薬品および食品 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014111664A JP2014111664A (ja) | 2014-06-19 |
| JP2014111664A5 true JP2014111664A5 (enExample) | 2014-08-07 |
| JP5906267B2 JP5906267B2 (ja) | 2016-04-20 |
Family
ID=44506965
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012501889A Active JP5503726B2 (ja) | 2010-02-26 | 2011-02-25 | 学習・記憶障害および運動障害などを伴う中枢神経変性疾患を改善する乾燥植物組織および植物組織抽出物ならびにこれらを含有する医薬品および食品 |
| JP2014052426A Active JP5906267B2 (ja) | 2010-02-26 | 2014-03-14 | 学習・記憶障害および運動障害などを伴う中枢神経変性疾患を改善する乾燥植物組織および植物組織抽出物ならびにこれらを含有する医薬品および食品 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012501889A Active JP5503726B2 (ja) | 2010-02-26 | 2011-02-25 | 学習・記憶障害および運動障害などを伴う中枢神経変性疾患を改善する乾燥植物組織および植物組織抽出物ならびにこれらを含有する医薬品および食品 |
Country Status (3)
| Country | Link |
|---|---|
| JP (2) | JP5503726B2 (enExample) |
| CN (1) | CN102883716B (enExample) |
| WO (1) | WO2011105568A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103930106A (zh) * | 2012-06-21 | 2014-07-16 | 小太郎汉方制药株式会社 | 中枢神经变性疾病的改善和/或治疗用组合物 |
| CN103479743B (zh) * | 2013-01-28 | 2015-07-08 | 钱昌美 | 治疗老年痴呆的药物组合物及其制备方法 |
| JP6179891B2 (ja) * | 2013-05-29 | 2017-08-16 | 要 有持 | 生産方法、加工方法、加工品及び茶 |
| JP2015053939A (ja) * | 2013-09-10 | 2015-03-23 | 久子 松野 | みかんの果皮の加工食品 |
| WO2015199118A1 (ja) * | 2014-06-26 | 2015-12-30 | 日本ゼオン株式会社 | 培養細胞内のerkまたはaktのリン酸化亢進方法、細胞の培養方法、およびリン酸化亢進剤 |
| JP2016056149A (ja) * | 2014-09-11 | 2016-04-21 | 日油株式会社 | 皮膚化粧料 |
| KR20190084143A (ko) * | 2014-11-12 | 2019-07-15 | 주식회사 파마코렉스 | 배뇨장애를 예방 또는 개선시키는 의약조성물, 배뇨장애 관련 수용체에 관한 길항제 또는 그 의약조성물 또는 길항제를 이용한 배뇨장애를 예방 또는 개선시키는 방법 |
| JP6238089B1 (ja) * | 2016-06-01 | 2017-11-29 | 株式会社三協ホールディングス | 医薬組成物および食品 |
| JP6898628B2 (ja) * | 2016-06-15 | 2021-07-07 | 国立大学法人広島大学 | 神経変性疾患治療剤 |
| CN107648349A (zh) * | 2017-10-30 | 2018-02-02 | 江西中医药大学 | 代代花在制备改善睡眠障碍或改善记忆力减退或治疗阿尔茨海默病药物或保健食品中的应用 |
| WO2019102602A1 (ja) * | 2017-11-27 | 2019-05-31 | 康 大泉 | スクリーニング方法 |
| KR101894491B1 (ko) * | 2018-04-30 | 2018-09-04 | 주식회사 뉴트라팜텍 | 지각 초임계 추출물을 유효성분으로 함유하는 기억력 또는 인지 기능 개선용 조성물 |
| CN112402409A (zh) * | 2020-12-11 | 2021-02-26 | 江汉大学 | 橘皮素在制备抑制β分泌酶活性药物中的应用 |
| CN115886258B (zh) * | 2022-12-30 | 2024-07-05 | 上海交大昂立股份有限公司 | 一种改善生理性记忆力衰减的复合益生菌组合物 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002053152A1 (en) * | 2001-01-08 | 2002-07-11 | Imperial College Of Science, Technology & Medicine | Composition containing flavonoids for treatment brain disorders |
| JP2008127325A (ja) * | 2006-11-20 | 2008-06-05 | Tokyoto Koreisha Kenkyu Fukushi Shinko Zaidan | リン酸化mbp産生促進剤 |
-
2011
- 2011-02-25 JP JP2012501889A patent/JP5503726B2/ja active Active
- 2011-02-25 CN CN201180011122.5A patent/CN102883716B/zh active Active
- 2011-02-25 WO PCT/JP2011/054358 patent/WO2011105568A1/ja not_active Ceased
-
2014
- 2014-03-14 JP JP2014052426A patent/JP5906267B2/ja active Active
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