JP2014005265A5 - - Google Patents

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Publication number
JP2014005265A5
JP2014005265A5 JP2012195912A JP2012195912A JP2014005265A5 JP 2014005265 A5 JP2014005265 A5 JP 2014005265A5 JP 2012195912 A JP2012195912 A JP 2012195912A JP 2012195912 A JP2012195912 A JP 2012195912A JP 2014005265 A5 JP2014005265 A5 JP 2014005265A5
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JP
Japan
Prior art keywords
cancer
deuterium
hydrogen
compound
composition
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Pending
Application number
JP2012195912A
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English (en)
Japanese (ja)
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JP2014005265A (ja
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Publication date
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Publication of JP2014005265A publication Critical patent/JP2014005265A/ja
Publication of JP2014005265A5 publication Critical patent/JP2014005265A5/ja
Pending legal-status Critical Current

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JP2012195912A 2012-06-22 2012-09-06 ピラゾール置換アミノ−ヘテロアリール化合物の誘導体 Pending JP2014005265A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261663221P 2012-06-22 2012-06-22
US61/663,221 2012-06-22
US201261680885P 2012-08-08 2012-08-08
US61/680,885 2012-08-08

Publications (2)

Publication Number Publication Date
JP2014005265A JP2014005265A (ja) 2014-01-16
JP2014005265A5 true JP2014005265A5 (enrdf_load_stackoverflow) 2015-10-01

Family

ID=49892488

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012195912A Pending JP2014005265A (ja) 2012-06-22 2012-09-06 ピラゾール置換アミノ−ヘテロアリール化合物の誘導体

Country Status (2)

Country Link
JP (1) JP2014005265A (enrdf_load_stackoverflow)
CN (1) CN103509008A (enrdf_load_stackoverflow)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103304552B (zh) * 2012-03-09 2016-12-28 广东东阳光药业有限公司 取代的吡啶化合物及其使用方法和用途
CN104650049B (zh) * 2013-08-28 2018-06-08 广东东阳光药业有限公司 取代的吡啶化合物及其使用方法和用途
CN108350006B (zh) * 2015-11-27 2020-01-03 正大天晴药业集团股份有限公司 氘修饰的Brigatinib衍生物、含有该化合物的药物组合物及其用途
JP6802850B2 (ja) * 2016-03-03 2020-12-23 深▲セン▼市塔吉瑞生物医▲薬▼有限公司Ｓｈｅｎｚｈｅｎ ＴａｒｇｅｔＲｘ，Ｉｎｃ． 大環状化合物および該化合物を含む組成物
CN114437058A (zh) * 2020-10-30 2022-05-06 珠海宇繁生物科技有限责任公司 氘代hpk1激酶抑制剂及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602005020465D1 (de) * 2004-08-26 2010-05-20 Pfizer Enantiomerenreine aminoheteroaryl-verbindungen als proteinkinasehemmer
ATE488237T1 (de) * 2005-12-05 2010-12-15 Pfizer Prod Inc Verfahren zur behandlung von abnormalem zellwachstum
CN101967140A (zh) * 2010-09-14 2011-02-09 郑州泰基鸿诺药物科技有限公司 氘代克里唑蒂尼及其衍生物、制备方法和应用

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